Gene description for CALM1
Gene name calmodulin 1 (phosphorylase kinase, delta)
Gene symbol CALM1
Other names/aliases CALML2
CAMI
CPVT4
DD132
LQT14
PHKD
caM
Species Homo sapiens
 Database cross references - CALM1
ExoCarta ExoCarta_801
Entrez Gene 801
HGNC 1442
MIM 114180
UniProt P62158  
 CALM1 identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells 17956143    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Hepatocellular carcinoma cells 26054723    
Neuroblastoma cells 25944692    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Saliva 19199708    
Squamous carcinoma cells 20124223    
Thymus 23844026    
Tracheobronchial cells 19190083    
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for CALM1
Molecular Function
    nitric-oxide synthase regulator activity GO:0030235 IEA
    protein phosphatase activator activity GO:0072542 IDA
    phospholipase binding GO:0043274 IPI
    thioesterase binding GO:0031996 IPI
    protein domain specific binding GO:0019904 IPI
    N-terminal myristoylation domain binding GO:0031997 IPI
    ion channel binding GO:0044325 IPI
    adenylate cyclase binding GO:0008179 IEA
    calcium ion binding GO:0005509 ISS
    protein serine/threonine kinase activator activity GO:0043539 TAS
    nitric-oxide synthase binding GO:0050998 IEA
    titin binding GO:0031432 IPI
    type 3 metabotropic glutamate receptor binding GO:0031800 IEA
    phosphatidylinositol 3-kinase binding GO:0043548 IEA
    calcium-dependent protein binding GO:0048306 IEA
    protein binding GO:0005515 IPI
    protein kinase binding GO:0019901 IPI
Biological Process
    small molecule metabolic process GO:0044281 TAS
    regulation of heart rate GO:0002027 IMP
    membrane organization GO:0061024 TAS
    activation of adenylate cyclase activity GO:0007190 IEA
    Fc-epsilon receptor signaling pathway GO:0038095 TAS
    nitric oxide metabolic process GO:0046209 TAS
    muscle contraction GO:0006936 TAS
    positive regulation of cyclic-nucleotide phosphodiesterase activity GO:0051343 IDA
    positive regulation of protein dephosphorylation GO:0035307 IDA
    vascular endothelial growth factor receptor signaling pathway GO:0048010 TAS
    innate immune response GO:0045087 TAS
    activation of phospholipase C activity GO:0007202 TAS
    regulation of cell communication by electrical coupling involved in cardiac conduction GO:1901844 IC
    positive regulation of cyclic nucleotide metabolic process GO:0030801 IDA
    platelet degranulation GO:0002576 TAS
    glucose metabolic process GO:0006006 TAS
    carbohydrate metabolic process GO:0005975 TAS
    substantia nigra development GO:0021762 IEP
    detection of calcium ion GO:0005513 IMP
    G-protein coupled receptor signaling pathway GO:0007186 TAS
    regulation of cardiac muscle contraction GO:0055117 IMP
    regulation of cytokinesis GO:0032465 IMP
    rhodopsin mediated signaling pathway GO:0016056 TAS
    positive regulation of ryanodine-sensitive calcium-release channel activity GO:0060316 IDA
    neurotrophin TRK receptor signaling pathway GO:0048011 TAS
    negative regulation of peptidyl-threonine phosphorylation GO:0010801 TAS
    signal transduction GO:0007165 TAS
    small GTPase mediated signal transduction GO:0007264 TAS
    platelet activation GO:0030168 TAS
    phototransduction, visible light GO:0007603 TAS
    stimulatory C-type lectin receptor signaling pathway GO:0002223 TAS
    epidermal growth factor receptor signaling pathway GO:0007173 TAS
    synaptic transmission GO:0007268 TAS
    inositol phosphate metabolic process GO:0043647 TAS
    glycogen catabolic process GO:0005980 TAS
    positive regulation of nitric-oxide synthase activity GO:0051000 IEA
    response to amphetamine GO:0001975 IEA
    regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 IDA
    regulation of nitric-oxide synthase activity GO:0050999 TAS
    regulation of high voltage-gated calcium channel activity GO:1901841 IEA
    fibroblast growth factor receptor signaling pathway GO:0008543 TAS
    response to corticosterone GO:0051412 IEA
    positive regulation of protein autophosphorylation GO:0031954 TAS
    positive regulation of peptidyl-threonine phosphorylation GO:0010800 TAS
    regulation of rhodopsin mediated signaling pathway GO:0022400 TAS
    negative regulation of ryanodine-sensitive calcium-release channel activity GO:0060315 ISS
    response to calcium ion GO:0051592 IDA
    blood coagulation GO:0007596 TAS
    positive regulation of protein serine/threonine kinase activity GO:0071902 TAS
    regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion GO:0010881 IC
    positive regulation of phosphoprotein phosphatase activity GO:0032516 IDA
Subcellular Localization
    extracellular region GO:0005576 TAS
    cytosol GO:0005829 TAS
    sarcomere GO:0030017 IDA
    calcium channel complex GO:0034704 IDA
    cytoplasm GO:0005737 TAS
    plasma membrane GO:0005886 TAS
    spindle microtubule GO:0005876 IDA
    nucleus GO:0005634 IDA
    centrosome GO:0005813 IDA
    vesicle GO:0031982 IDA
    spindle pole GO:0000922 IDA
    nucleoplasm GO:0005654 TAS
    extracellular exosome GO:0070062 IDA
    growth cone GO:0030426 IEA
 Experiment description of studies that identified CALM1 in exosomes
1
Experiment ID 20
ISEV standards
EM
EV Biophysical techniques
HSP90
EV Cytosolic markers
CD63|CD81|LAMP1
EV Membrane markers
GOLGA2|cytochrome c
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
2
Experiment ID 207
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP70
EV Cytosolic markers
FLOT1
EV Membrane markers
VDAC
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ.
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 208
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP70
EV Cytosolic markers
FLOT1
EV Membrane markers
VDAC
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ.
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
4
Experiment ID 209
ISEV standards
EV Biophysical techniques
TSG101|HSP70
EV Cytosolic markers
FLOT1
EV Membrane markers
VDAC
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ.
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
5
Experiment ID 282
ISEV standards
CEM
EV Biophysical techniques
Alix|TSG101
EV Cytosolic markers
CD63|CD81|EpCAM
EV Membrane markers
EV Negative markers
DLS
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors Xu R, Greening DW, Rai A, Ji H, Simpson RJ.
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
6
Experiment ID 283
ISEV standards
CEM
EV Biophysical techniques
Alix|TSG101
EV Cytosolic markers
CD63|CD81|EpCAM
EV Membrane markers
EV Negative markers
DLS
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors Xu R, Greening DW, Rai A, Ji H, Simpson RJ.
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
7
Experiment ID 286
ISEV standards
CEM
EV Biophysical techniques
Alix|TSG101
EV Cytosolic markers
CD63|CD81|EpCAM
EV Membrane markers
EV Negative markers
DLS
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors Xu R, Greening DW, Rai A, Ji H, Simpson RJ.
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
8
Experiment ID 236
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
9
Experiment ID 224
ISEV standards
EM|AFM
EV Biophysical techniques
Alix|TSG101
EV Cytosolic markers
CD63|CD81
EV Membrane markers
GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
10
Experiment ID 211
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
cytochrome c|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 212
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
Cytochrome C|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 66
ISEV standards
IEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
CD63|CD81
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
13
Experiment ID 191
ISEV standards
EV Biophysical techniques
Alix
EV Cytosolic markers
CD81|CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 34
ISEV standards
EM|IEM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD63|MHCI|MHCII
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19190083    
Organism Homo sapiens
Experiment description Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense.
Authors Kesimer M, Scull M, Brighton B, Demaria G, Burns K, O'Neal W, Pickles RJ, Sheehan JK
Journal name FASEB
Publication year 2009
Sample Tracheobronchial cells
Sample name Tracheobronchial epithelial cells
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density 1.16 -1.18 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study Mass spectrometry [QTOF]
Western blotting
Immunoelectron Microscopy
FACS
16
Experiment ID 196
ISEV standards
EM
EV Biophysical techniques
Alix|TSG101|HSP70
EV Cytosolic markers
CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors Raj DA, Fiume I, Capasso G, Pocsfalvi G.
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 197
ISEV standards
EM
EV Biophysical techniques
Alix|TSG101|HSP70
EV Cytosolic markers
CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors Raj DA, Fiume I, Capasso G, Pocsfalvi G.
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CALM1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PDE1A  
Invitro Homo sapiens
2 CALD1  
Affinity Capture-MS Homo sapiens
3 SNCA 6622
Reconstituted Complex Homo sapiens
4 CNN1 1264
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
5 MYLK 4638
Reconstituted Complex Homo sapiens
6 CCNA2 890
Reconstituted Complex Homo sapiens
7 PPEF1  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
8 OPRM1 4988
Reconstituted Complex Homo sapiens
9 PCNT2  
Reconstituted Complex Homo sapiens
10 YWHAE 7531
Invitro Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
11 AKAP9 10142
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
12 GRK5 2869
Reconstituted Complex Homo sapiens
13 GAP43  
Affinity Capture-MS Homo sapiens
14 KCNQ3  
Invivo Homo sapiens
Invitro Homo sapiens
Two-hybrid Homo sapiens
15 KCNQ5  
Invivo Homo sapiens
Invitro Homo sapiens
Two-hybrid Homo sapiens
16 GRK4  
Reconstituted Complex Homo sapiens
17 PPEF2  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
18 HSP90AA1 3320
Affinity Capture-MS Homo sapiens
19 RALB 5899
Affinity Capture-MS Homo sapiens
20 RYR1 6261
Invitro Homo sapiens
21 GRM7 2917
Invivo Homo sapiens
Invitro Homo sapiens
22 ESR2  
Affinity Capture-MS Homo sapiens
23 SNTA1 6640
Invivo Homo sapiens
24 ADD2 119
Invivo Homo sapiens
25 TCF4  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
26 TRPV1  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
27 RIT2  
Reconstituted Complex Homo sapiens
28 MAPT  
Reconstituted Complex Homo sapiens
29 TTN 7273
Invitro Homo sapiens
30 AKAP5  
Invitro Homo sapiens
31 SLC9A1 6548
Far Western Homo sapiens
32 KCNQ2  
Invivo Homo sapiens
Invitro Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
33 TCF3  
Reconstituted Complex Homo sapiens
34 MYO9B 4650
Affinity Capture-Western Homo sapiens
35 IQGAP1 8826
Reconstituted Complex Homo sapiens
36 RAB3B 5865
Affinity Capture-MS Homo sapiens
37 EMP3  
Invivo Homo sapiens
Invitro Homo sapiens
Two-hybrid Homo sapiens
38 NEUROD1  
Affinity Capture-MS Homo sapiens
39 EDF1 8721
Invivo Homo sapiens
Invitro Homo sapiens
Affinity Capture-MS Homo sapiens
40 KCNN2  
Co-crystal Structure Homo sapiens
41 AR 367
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
42 ADD1 118
Invivo Homo sapiens
Affinity Capture-MS Homo sapiens
Phenotypic Suppression Homo sapiens
43 PHKG1  
Invitro Homo sapiens
Invivo Homo sapiens
44 LYST 1130
Invivo Homo sapiens
Two-hybrid Homo sapiens
45 CCND1 595
Invivo Homo sapiens
46 CAMK2G 818
Reconstituted Complex Homo sapiens
47 SYT1 6857
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which CALM1 is involved
PathwayEvidenceSource
Activation of Ca-permeable Kainate Receptor TAS Reactome
Activation of CaMK IV TAS Reactome
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers TAS Reactome
Ca2+ pathway TAS Reactome
Calmodulin induced events TAS Reactome
Calmodulin induced events TAS Reactome
CaM pathway TAS Reactome
CaM pathway TAS Reactome
Cam-PDE 1 activation TAS Reactome
Cam-PDE 1 activation TAS Reactome
CaMK IV-mediated phosphorylation of CREB TAS Reactome
CaMK IV-mediated phosphorylation of CREB TAS Reactome
CLEC7A (Dectin-1) induces NFAT activation TAS Reactome
CREB phosphorylation through the activation of CaMKII TAS Reactome
CREB phosphorylation through the activation of CaMKK TAS Reactome
DARPP-32 events TAS Reactome
eNOS activation TAS Reactome
FCERI mediated Ca+2 mobilization TAS Reactome
Glycogen breakdown (glycogenolysis) TAS Reactome
Inactivation, recovery and regulation of the phototransduction cascade TAS Reactome
Platelet degranulation TAS Reactome
Ras activation uopn Ca2+ infux through NMDA receptor TAS Reactome
RHO GTPases activate IQGAPs TAS Reactome
RHO GTPases activate PAKs TAS Reactome
Smooth Muscle Contraction TAS Reactome
Synthesis of IP3 and IP4 in the cytosol TAS Reactome
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation TAS Reactome
Translocation of GLUT4 to the plasma membrane TAS Reactome
VEGFR2 mediated cell proliferation TAS Reactome
VEGFR2 mediated vascular permeability TAS Reactome





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