Gene description for PLEKHG3
Gene name pleckstrin homology domain containing, family G (with RhoGef domain) member 3
Gene symbol PLEKHG3
Other names/aliases ARHGEF43
KIAA0599
Species Homo sapiens
 Database cross references - PLEKHG3
ExoCarta ExoCarta_26030
Entrez Gene 26030
HGNC 20364
UniProt A1L390  
 PLEKHG3 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for PLEKHG3
Molecular Function
    Rho guanyl-nucleotide exchange factor activity GO:0005089 IEA
Biological Process
    positive regulation of GTPase activity GO:0043547 IEA
 Experiment description of studies that identified PLEKHG3 in exosomes
1
Experiment ID 126
ISEV standards
EV Biophysical techniques
GAPDH
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for PLEKHG3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PLEKHG3 is involved
No pathways found





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