Gene description for PMPCB
Gene name peptidase (mitochondrial processing) beta
Gene symbol PMPCB
Other names/aliases Beta-MPP
MPP11
MPPB
MPPP52
P-52
Species Homo sapiens
 Database cross references - PMPCB
ExoCarta ExoCarta_9512
Vesiclepedia VP_9512
Entrez Gene 9512
HGNC 9119
MIM 603131
UniProt O75439  
 PMPCB identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
 Gene ontology annotations for PMPCB
Molecular Function
    metalloendopeptidase activity GO:0004222 IBA
    metalloendopeptidase activity GO:0004222 IDA
    metalloendopeptidase activity GO:0004222 TAS
    metal ion binding GO:0046872 IEA
Biological Process
    protein processing involved in protein targeting to mitochondrion GO:0006627 IBA
    protein processing involved in protein targeting to mitochondrion GO:0006627 IDA
    protein processing involved in protein targeting to mitochondrion GO:0006627 NAS
    mitochondrial calcium ion transmembrane transport GO:0006851 TAS
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 IDA
    mitochondrion GO:0005739 NAS
    mitochondrial matrix GO:0005759 TAS
    mitochondrial processing peptidase complex GO:0017087 NAS
 Experiment description of studies that identified PMPCB in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
15
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
18
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
24
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for PMPCB
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 COX5A 9377
Proximity Label-MS Homo sapiens
3 RIT1 6016
Negative Genetic Homo sapiens
4 AFG3L2 10939
Proximity Label-MS Homo sapiens
5 LYRM2  
Affinity Capture-MS Homo sapiens
6 MRPL27 51264
Proximity Label-MS Homo sapiens
7 IARS2 55699
Proximity Label-MS Homo sapiens
8 GLUD1 2746
Proximity Label-MS Homo sapiens
9 MRPL48  
Proximity Label-MS Homo sapiens
10 THEM4  
Proximity Label-MS Homo sapiens
11 ATP5J2-PTCD1  
Proximity Label-MS Homo sapiens
12 PDHX 8050
Proximity Label-MS Homo sapiens
13 DNAJC8 22826
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 NDUFS6  
Proximity Label-MS Homo sapiens
15 ADCK3  
Affinity Capture-MS Homo sapiens
16 NDUFS1 4719
Proximity Label-MS Homo sapiens
17 MRPL30  
Proximity Label-MS Homo sapiens
18 MRPL17  
Proximity Label-MS Homo sapiens
19 PHYHIPL  
Affinity Capture-MS Homo sapiens
20 SPRYD4 283377
Affinity Capture-MS Homo sapiens
21 GTPBP10  
Proximity Label-MS Homo sapiens
22 RPA2 6118
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
23 PDK3 5165
Proximity Label-MS Homo sapiens
24 TRUB2  
Affinity Capture-MS Homo sapiens
25 POLG  
Proximity Label-MS Homo sapiens
26 HCRT  
Affinity Capture-MS Homo sapiens
27 NUBPL 80224
Proximity Label-MS Homo sapiens
28 MRPL24  
Proximity Label-MS Homo sapiens
29 CDK5RAP1  
Proximity Label-MS Homo sapiens
30 ETFB 2109
Proximity Label-MS Homo sapiens
31 C4orf26  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 MRPL50 54534
Proximity Label-MS Homo sapiens
33 HARS2 23438
Proximity Label-MS Homo sapiens
34 GATB  
Proximity Label-MS Homo sapiens
35 PDHB 5162
Proximity Label-MS Homo sapiens
36 MRPL49 740
Proximity Label-MS Homo sapiens
37 MRPL23 6150
Proximity Label-MS Homo sapiens
38 KRTAP13-2  
Affinity Capture-MS Homo sapiens
39 PNPLA8 50640
Proximity Label-MS Homo sapiens
40 NDUFS2 4720
Proximity Label-MS Homo sapiens
41 NIPSNAP1 8508
Proximity Label-MS Homo sapiens
42 CARS2 79587
Proximity Label-MS Homo sapiens
43 C7orf55  
Affinity Capture-MS Homo sapiens
44 MRPS35 60488
Proximity Label-MS Homo sapiens
45 WTAP 9589
Co-fractionation Homo sapiens
46 PARK2  
Affinity Capture-MS Homo sapiens
47 ATP5D 513
Proximity Label-MS Homo sapiens
48 MEI1  
Affinity Capture-MS Homo sapiens
49 NDUFS3 4722
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
50 CCDC69 26112
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 ECI2 10455
Proximity Label-MS Homo sapiens
52 PRDX3 10935
Proximity Label-MS Homo sapiens
53 MRPS31  
Proximity Label-MS Homo sapiens
54 PMPCA 23203
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
55 COQ9  
Affinity Capture-MS Homo sapiens
56 CCS 9973
Co-fractionation Homo sapiens
57 PTPMT1 114971
Affinity Capture-MS Homo sapiens
58 CHCHD2  
Affinity Capture-MS Homo sapiens
59 NIT1 4817
Affinity Capture-MS Homo sapiens
60 MRPS23 51649
Proximity Label-MS Homo sapiens
61 PPM1K  
Affinity Capture-MS Homo sapiens
62 MRPS5 64969
Proximity Label-MS Homo sapiens
63 RPRD1A  
Co-fractionation Homo sapiens
64 HINT2 84681
Proximity Label-MS Homo sapiens
65 COQ3  
Affinity Capture-MS Homo sapiens
66 MRPS24 64951
Proximity Label-MS Homo sapiens
67 MRPL12 6182
Proximity Label-MS Homo sapiens
68 MRPS27 23107
Proximity Label-MS Homo sapiens
69 ETFA 2108
Proximity Label-MS Homo sapiens
70 FXN  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
71 SOST  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 LACE1  
Affinity Capture-MS Homo sapiens
73 POLRMT 5442
Proximity Label-MS Homo sapiens
74 ATP5O 539
Proximity Label-MS Homo sapiens
75 FDX1L  
Co-fractionation Homo sapiens
76 NNT 23530
Proximity Label-MS Homo sapiens
77 SMEK1 55671
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
78 ERAL1  
Proximity Label-MS Homo sapiens
79 MRPL39 54148
Proximity Label-MS Homo sapiens
80 NDUFAF1  
Proximity Label-MS Homo sapiens
81 IVD 3712
Affinity Capture-MS Homo sapiens
82 NDUFAB1 4706
Proximity Label-MS Homo sapiens
83 SERF2 10169
Affinity Capture-MS Homo sapiens
84 ATP5H 10476
Proximity Label-MS Homo sapiens
85 SLC30A9 10463
Proximity Label-MS Homo sapiens
86 COQ10A  
Affinity Capture-MS Homo sapiens
87 BCS1L 617
Proximity Label-MS Homo sapiens
88 MRPL44  
Proximity Label-MS Homo sapiens
89 GSTO1 9446
Co-fractionation Homo sapiens
90 MRPL4 51073
Proximity Label-MS Homo sapiens
91 ACSF2 80221
Co-fractionation Homo sapiens
92 PREPL 9581
Proximity Label-MS Homo sapiens
93 NDUFA6  
Proximity Label-MS Homo sapiens
94 ADCK4 79934
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
95 MRPL47 57129
Proximity Label-MS Homo sapiens
96 CGB2  
Affinity Capture-MS Homo sapiens
97 MTERF3  
Proximity Label-MS Homo sapiens
98 TRMT10C 54931
Proximity Label-MS Homo sapiens
99 ACP6 51205
Affinity Capture-MS Homo sapiens
100 QRSL1  
Proximity Label-MS Homo sapiens
101 PNPT1 87178
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
102 MDH2 4191
Proximity Label-MS Homo sapiens
103 STOML2 30968
Proximity Label-MS Homo sapiens
104 MRPL38  
Proximity Label-MS Homo sapiens
105 ALAS1  
Proximity Label-MS Homo sapiens
106 TRMT61B  
Proximity Label-MS Homo sapiens
107 MRPL57  
Proximity Label-MS Homo sapiens
108 MRPL32 64983
Proximity Label-MS Homo sapiens
109 ATP5A1 498
Affinity Capture-MS Homo sapiens
110 MRPS33  
Proximity Label-MS Homo sapiens
111 PRDX5 25824
Co-fractionation Homo sapiens
112 NDUFS4 4724
Proximity Label-MS Homo sapiens
113 PCK2 5106
Co-fractionation Homo sapiens
114 SUCLG1 8802
Co-fractionation Homo sapiens
115 MRPL45 84311
Proximity Label-MS Homo sapiens
116 MRPS26 64949
Proximity Label-MS Homo sapiens
117 SBF2 81846
Proximity Label-MS Homo sapiens
118 MRPS34 65993
Proximity Label-MS Homo sapiens
119 NDUFS8 4728
Proximity Label-MS Homo sapiens
120 ANGEL2 90806
Proximity Label-MS Homo sapiens
121 PTCD3 55037
Proximity Label-MS Homo sapiens
122 ACOT2 10965
Proximity Label-MS Homo sapiens
123 CDRT15  
Affinity Capture-MS Homo sapiens
124 NT5DC2 64943
Proximity Label-MS Homo sapiens
125 ATPAF1  
Proximity Label-MS Homo sapiens
126 PAM16  
Proximity Label-MS Homo sapiens
127 ACOT1 641371
Proximity Label-MS Homo sapiens
128 SLIRP 81892
Proximity Label-MS Homo sapiens
129 ACACA 31
Positive Genetic Homo sapiens
130 MRPS14  
Proximity Label-MS Homo sapiens
131 KDELC2 143888
Co-fractionation Homo sapiens
132 MMAB 326625
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
133 TAMM41  
Affinity Capture-MS Homo sapiens
134 UQCRC2 7385
Proximity Label-MS Homo sapiens
135 MYH9 4627
Affinity Capture-MS Homo sapiens
136 MRPS18B 28973
Proximity Label-MS Homo sapiens
137 OGT 8473
Co-fractionation Homo sapiens
138 RTN4IP1  
Proximity Label-MS Homo sapiens
139 MRPS6  
Proximity Label-MS Homo sapiens
140 TPI1 7167
Co-fractionation Homo sapiens
141 KRT75 9119
Affinity Capture-MS Homo sapiens
142 HNRNPAB 3182
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
143 C9orf170  
Affinity Capture-MS Homo sapiens
144 POLDIP2 26073
Proximity Label-MS Homo sapiens
145 GFM1 85476
Proximity Label-MS Homo sapiens
146 PDHA1 5160
Proximity Label-MS Homo sapiens
147 MRPL3  
Proximity Label-MS Homo sapiens
148 ENO1 2023
Affinity Capture-RNA Homo sapiens
149 LYRM4 57128
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
150 DBT 1629
Proximity Label-MS Homo sapiens
151 PDE12 201626
Proximity Label-MS Homo sapiens
152 SLC11A2 4891
Affinity Capture-MS Homo sapiens
153 PAK7  
Affinity Capture-MS Homo sapiens
154 MTRF1L  
Proximity Label-MS Homo sapiens
155 GMPS 8833
Co-fractionation Homo sapiens
156 MRPL42  
Proximity Label-MS Homo sapiens
157 HNRNPA3 220988
Proximity Label-MS Homo sapiens
158 MRPL14 64928
Proximity Label-MS Homo sapiens
159 ALDH2 217
Proximity Label-MS Homo sapiens
160 ADCK1  
Affinity Capture-MS Homo sapiens
161 ADCK5  
Affinity Capture-MS Homo sapiens
162 ABCB7 22
Proximity Label-MS Homo sapiens
163 COX4I1 1327
Proximity Label-MS Homo sapiens
164 GTPBP3  
Proximity Label-MS Homo sapiens
165 NDUFV1 4723
Proximity Label-MS Homo sapiens
166 PPP4R1 9989
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
167 CISD3 284106
Affinity Capture-MS Homo sapiens
168 OXA1L  
Proximity Label-MS Homo sapiens
169 HNRNPDL 9987
Proximity Label-MS Homo sapiens
170 PHB 5245
Proximity Label-MS Homo sapiens
171 ECH1 1891
Proximity Label-MS Homo sapiens
172 C15orf48  
Affinity Capture-MS Homo sapiens
173 SLX4  
Affinity Capture-MS Homo sapiens
174 ACAT1 38
Proximity Label-MS Homo sapiens
175 MRPL40 64976
Proximity Label-MS Homo sapiens
176 WBSCR16  
Affinity Capture-MS Homo sapiens
177 MRPL21 219927
Proximity Label-MS Homo sapiens
178 HADHA 3030
Proximity Label-MS Homo sapiens
179 PPP4R2  
Affinity Capture-MS Homo sapiens
180 THG1L 54974
Proximity Label-MS Homo sapiens
181 MRPL10 124995
Proximity Label-MS Homo sapiens
182 DAP3 7818
Proximity Label-MS Homo sapiens
183 MCCC2 64087
Affinity Capture-MS Homo sapiens
184 SMEK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
185 ATP5F1 515
Proximity Label-MS Homo sapiens
186 NDUFA9 4704
Proximity Label-MS Homo sapiens
187 KRT86  
Affinity Capture-MS Homo sapiens
188 LETM1 3954
Proximity Label-MS Homo sapiens
189 PPA1 5464
Co-fractionation Homo sapiens
190 HN1 51155
Co-fractionation Homo sapiens
191 MRPS7 51081
Proximity Label-MS Homo sapiens
192 GCDH 2639
Proximity Label-MS Homo sapiens
193 C2orf47  
Affinity Capture-MS Homo sapiens
194 MRPL9 65005
Proximity Label-MS Homo sapiens
195 ACADM 34
Proximity Label-MS Homo sapiens
196 MRPL16  
Proximity Label-MS Homo sapiens
197 OAT 4942
Proximity Label-MS Homo sapiens
198 NFS1 9054
Proximity Label-MS Homo sapiens
199 CUL3 8452
Affinity Capture-MS Homo sapiens
200 DES 1674
Affinity Capture-MS Homo sapiens
201 NPPA  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
202 PYCR1 5831
Proximity Label-MS Homo sapiens
203 THNSL1 79896
Proximity Label-MS Homo sapiens
204 HSD17B10 3028
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
205 ELAC2 60528
Proximity Label-MS Homo sapiens
206 GADD45GIP1  
Proximity Label-MS Homo sapiens
207 DHX30 22907
Proximity Label-MS Homo sapiens
208 BOLA1 51027
Affinity Capture-MS Homo sapiens
209 VARS2  
Proximity Label-MS Homo sapiens
210 PYCR2 29920
Proximity Label-MS Homo sapiens
211 MTIF2 4528
Proximity Label-MS Homo sapiens
212 NPSR1  
Two-hybrid Homo sapiens
213 ECHS1 1892
Proximity Label-MS Homo sapiens
214 OCIAD1 54940
Affinity Capture-MS Homo sapiens
215 NXF1 10482
Affinity Capture-RNA Homo sapiens
216 MRPL15 29088
Proximity Label-MS Homo sapiens
217 AMY1C 278
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
218 PTPN7 5778
Affinity Capture-MS Homo sapiens
219 MRPL1  
Proximity Label-MS Homo sapiens
220 MRPL52  
Proximity Label-MS Homo sapiens
221 MRPL19 9801
Proximity Label-MS Homo sapiens
222 RPA3 6119
Proximity Label-MS Homo sapiens
223 NDUFA2 4695
Proximity Label-MS Homo sapiens
224 FASTKD2  
Proximity Label-MS Homo sapiens
225 TACO1  
Proximity Label-MS Homo sapiens
226 MRPL37 51253
Proximity Label-MS Homo sapiens
227 DLST 1743
Proximity Label-MS Homo sapiens
228 ATP5B 506
Proximity Label-MS Homo sapiens
229 HSDL2 84263
Proximity Label-MS Homo sapiens
230 TXNL1 9352
Co-fractionation Homo sapiens
231 PPA2 27068
Proximity Label-MS Homo sapiens
232 PABPN1L  
Affinity Capture-MS Homo sapiens
233 ACAD9 28976
Proximity Label-MS Homo sapiens
234 MRPS36 92259
Proximity Label-MS Homo sapiens
235 MTHFD2 10797
Proximity Label-MS Homo sapiens
236 PDPR 55066
Proximity Label-MS Homo sapiens
237 HSPE1 3336
Proximity Label-MS Homo sapiens
238 KRAS 3845
Negative Genetic Homo sapiens
239 NDUFA12 55967
Proximity Label-MS Homo sapiens
240 HSPD1 3329
Proximity Label-MS Homo sapiens
241 HSPA9 3313
Proximity Label-MS Homo sapiens
242 DLAT 1737
Proximity Label-MS Homo sapiens
243 PDP1 54704
Affinity Capture-MS Homo sapiens
244 NFATC2  
Affinity Capture-MS Homo sapiens
245 MRPL18 29074
Proximity Label-MS Homo sapiens
246 UQCRC1 7384
Proximity Label-MS Homo sapiens
247 C10orf2 56652
Proximity Label-MS Homo sapiens
248 PPIF 10105
Proximity Label-MS Homo sapiens
249 NDUFA5 4698
Proximity Label-MS Homo sapiens
250 NIT2 56954
Co-fractionation Homo sapiens
251 AK4 205
Proximity Label-MS Homo sapiens
252 MARK3 4140
Two-hybrid Homo sapiens
253 CLPP 8192
Proximity Label-MS Homo sapiens
254 APOA1BP 128240
Co-fractionation Homo sapiens
255 CS 1431
Proximity Label-MS Homo sapiens
256 GLS 2744
Proximity Label-MS Homo sapiens
257 CLPX 10845
Proximity Label-MS Homo sapiens
258 C17orf80 55028
Proximity Label-MS Homo sapiens
259 DHTKD1 55526
Proximity Label-MS Homo sapiens
260 NDUFA7 4701
Proximity Label-MS Homo sapiens
261 AARS2  
Proximity Label-MS Homo sapiens
262 NDUFAF2  
Proximity Label-MS Homo sapiens
263 LRPPRC 10128
Proximity Label-MS Homo sapiens
264 MRPS9 64965
Proximity Label-MS Homo sapiens
265 ALDH4A1 8659
Proximity Label-MS Homo sapiens
266 MRPL22  
Proximity Label-MS Homo sapiens
267 ATP5J 522
Proximity Label-MS Homo sapiens
268 MRPS2 51116
Proximity Label-MS Homo sapiens
269 COQ5  
Affinity Capture-MS Homo sapiens
270 COQ6 51004
Affinity Capture-MS Homo sapiens
271 WARS2  
Proximity Label-MS Homo sapiens
272 ICT1 3396
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
273 MRPS28  
Proximity Label-MS Homo sapiens
274 SUCLG2 8801
Co-fractionation Homo sapiens
275 NME4 4833
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
276 ABHD10 55347
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
277 SPINK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
278 HADH 3033
Proximity Label-MS Homo sapiens
279 MRPL53  
Proximity Label-MS Homo sapiens
280 BCKDHA 593
Proximity Label-MS Homo sapiens
281 CECR5 27440
Affinity Capture-MS Homo sapiens
282 MRPS17 51373
Proximity Label-MS Homo sapiens
283 MRPL28 10573
Proximity Label-MS Homo sapiens
284 DNAJA3 9093
Proximity Label-MS Homo sapiens
285 ADCK2  
Affinity Capture-MS Homo sapiens
286 C17orf89  
Affinity Capture-MS Homo sapiens
287 COQ7  
Affinity Capture-MS Homo sapiens
288 LYPLAL1 127018
Proximity Label-MS Homo sapiens
289 GRPEL1 80273
Proximity Label-MS Homo sapiens
290 NDUFV3 4731
Proximity Label-MS Homo sapiens
291 MRPS10 55173
Proximity Label-MS Homo sapiens
292 SUCLA2 8803
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
293 SHMT2 6472
Affinity Capture-RNA Homo sapiens
Proximity Label-MS Homo sapiens
294 MRPS18C  
Proximity Label-MS Homo sapiens
295 SPATA20  
Affinity Capture-MS Homo sapiens
296 NPPB  
Affinity Capture-MS Homo sapiens
297 OGDHL  
Proximity Label-MS Homo sapiens
298 GATC  
Proximity Label-MS Homo sapiens
299 MAGIX 79917
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
300 ME2 4200
Proximity Label-MS Homo sapiens
301 MRPS30 10884
Proximity Label-MS Homo sapiens
302 NUP50 10762
Co-fractionation Homo sapiens
303 NDUFAF3 25915
Proximity Label-MS Homo sapiens
304 LARS2 23395
Proximity Label-MS Homo sapiens
305 MRPL41 64975
Proximity Label-MS Homo sapiens
306 MOV10 4343
Affinity Capture-RNA Homo sapiens
307 MINPP1 9562
Co-fractionation Homo sapiens
308 RNMTL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
309 MRPL13  
Proximity Label-MS Homo sapiens
310 VWA8 23078
Proximity Label-MS Homo sapiens
311 CREG1 8804
Co-fractionation Homo sapiens
312 DEFB1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
313 MRPL46  
Proximity Label-MS Homo sapiens
314 MRPL20 55052
Proximity Label-MS Homo sapiens
315 ANXA5 308
Co-fractionation Homo sapiens
316 DHRS4 10901
Affinity Capture-MS Homo sapiens
317 MRPS16  
Proximity Label-MS Homo sapiens
318 GRSF1 2926
Proximity Label-MS Homo sapiens
319 SERBP1 26135
Affinity Capture-MS Homo sapiens
320 TXNIP 10628
Affinity Capture-MS Homo sapiens
321 IBA57  
Proximity Label-MS Homo sapiens
322 NDUFAF4 29078
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
323 OXCT2  
Affinity Capture-MS Homo sapiens
324 MRPL2 51069
Proximity Label-MS Homo sapiens
325 MRPL55  
Proximity Label-MS Homo sapiens
326 MRPS25 64432
Proximity Label-MS Homo sapiens
327 NDUFV2 4729
Proximity Label-MS Homo sapiens
328 OGDH 4967
Proximity Label-MS Homo sapiens
329 MRPS22 56945
Proximity Label-MS Homo sapiens
330 FASTKD5  
Proximity Label-MS Homo sapiens
331 HNRNPL 3191
Proximity Label-MS Homo sapiens
332 MRPL51 51258
Proximity Label-MS Homo sapiens
333 PTGER4  
Two-hybrid Homo sapiens
334 NVL  
Affinity Capture-MS Homo sapiens
335 MRPS18A  
Proximity Label-MS Homo sapiens
336 MRPL43 84545
Proximity Label-MS Homo sapiens
337 DDX28  
Proximity Label-MS Homo sapiens
338 TIMM44 10469
Proximity Label-MS Homo sapiens
339 ECSIT 51295
Proximity Label-MS Homo sapiens
340 NDUFS7 374291
Proximity Label-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here