ExoCarta: Gene summary

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Gene description for MRPL4
Gene name	mitochondrial ribosomal protein L4
Gene symbol	MRPL4
Other names/aliases	CGI-28 L4mt
Species	Homo sapiens
Database cross references - MRPL4
ExoCarta	ExoCarta_51073
Vesiclepedia	VP_51073
Entrez Gene	51073
HGNC	14276
MIM	611823
UniProt	Q9BYD3
MRPL4 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells	36408942
Bone marrow mesenchymal stem cells	36408942
Bone marrow mesenchymal stem cells	36408942
Bone marrow mesenchymal stem cells	36408942

Gene ontology annotations for MRPL4

Molecular Function
	RNA binding	GO:0003723	HDA
	structural constituent of ribosome	GO:0003735	IBA
	protein binding	GO:0005515	IPI
Biological Process
	mitochondrial translation	GO:0032543	NAS
Subcellular Localization
	mitochondrion	GO:0005739	HTP
	mitochondrion	GO:0005739	IDA
	mitochondrial inner membrane	GO:0005743	NAS
	mitochondrial inner membrane	GO:0005743	TAS
	mitochondrial large ribosomal subunit	GO:0005762	IDA
	mitochondrial large ribosomal subunit	GO:0005762	NAS

Experiment description of studies that identified MRPL4 in exosomes

Experiment ID

489

MISEV standards
✔ EM	Biophysical techniques
✔ Cd9\|Cd81\|Cd63\|Gapdh\|Sdcbp\|Lamp1\|Aqp1\|Rab5a\|Icam1\|Cd82\|Itga2b\|Tsg101\|Lamp2\|Rab35\|Flot1\|Flot2\|Cd151\|Rab5b\|Tfrc\|Uchl1	Enriched markers
✔ Canx	Negative markers
✔ NTA	Particle analysis

Identified molecule

Protein

Identification method

Mass spectrometry

PubMed ID

36408942

Organism

Rattus norvegicus

Experiment description

Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells

Authors

"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."

Journal name

Proteomics

Publication year

2023

Sample

Bone marrow mesenchymal stem cells

Sample name

BMSC - Passage 6

Isolation/purification methods

Differential centrifugation
Filtration
Ultracentrifugation

Flotation density

Molecules identified in the study

Protein

Methods used in the study

Western blotting
Mass spectometry

Experiment ID

490

MISEV standards
✔ EM	Biophysical techniques
✔ Cd9\|Cd81\|Cd63\|Gapdh\|Sdcbp\|Lamp1\|Aqp1\|Rab5a\|Icam1\|Cd82\|Itga2b\|Tsg101\|Lamp2\|Rab35\|Flot1\|Flot2\|Cd151\|Rab5b\|Tfrc\|Uchl1	Enriched markers
✔ Canx	Negative markers
✔ NTA	Particle analysis

Identified molecule

Protein

Identification method

Mass spectrometry

PubMed ID

36408942

Organism

Rattus norvegicus

Experiment description

Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells

Authors

"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."

Journal name

Proteomics

Publication year

2023

Sample

Bone marrow mesenchymal stem cells

Sample name

BMSC - Passage 7

Isolation/purification methods

Differential centrifugation
Filtration
Ultracentrifugation

Flotation density

Molecules identified in the study

Protein

Methods used in the study

Western blotting
Mass spectometry

Experiment ID

491

MISEV standards
✔ EM	Biophysical techniques
✔ Cd9\|Cd81\|Cd63\|Gapdh\|Sdcbp\|Lamp1\|Aqp1\|Rab5a\|Icam1\|Cd82\|Itga2b\|Tsg101\|Lamp2\|Rab35\|Flot1\|Flot2\|Cd151\|Rab5b\|Tfrc\|Uchl1	Enriched markers
✔ Canx	Negative markers
✔ NTA	Particle analysis

Identified molecule

Protein

Identification method

Mass spectrometry

PubMed ID

36408942

Organism

Rattus norvegicus

Experiment description

Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells

Authors

"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."

Journal name

Proteomics

Publication year

2023

Sample

Bone marrow mesenchymal stem cells

Sample name

BMSC - Passage 8

Isolation/purification methods

Differential centrifugation
Filtration
Ultracentrifugation

Flotation density

Molecules identified in the study

Protein

Methods used in the study

Western blotting
Mass spectometry

Experiment ID

492

MISEV standards
✔ EM	Biophysical techniques
✔ Cd9\|Cd81\|Cd63\|Gapdh\|Sdcbp\|Lamp1\|Aqp1\|Rab5a\|Icam1\|Cd82\|Itga2b\|Tsg101\|Lamp2\|Rab35\|Flot1\|Flot2\|Cd151\|Rab5b\|Tfrc\|Uchl1	Enriched markers
✔ Canx	Negative markers
✔ NTA	Particle analysis

Identified molecule

Protein

Identification method

Mass spectrometry

PubMed ID

36408942

Organism

Rattus norvegicus

Experiment description

Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells

Authors

"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."

Journal name

Proteomics

Publication year

2023

Sample

Bone marrow mesenchymal stem cells

Sample name

BMSC - Passage 9

Isolation/purification methods

Differential centrifugation
Filtration
Ultracentrifugation

Flotation density

Molecules identified in the study

Protein

Methods used in the study

Western blotting
Mass spectometry

Protein-protein interactions for MRPL4

Protein Interactor

ExoCarta ID

Identification method

PubMed

Species

CFAP20

29105

Affinity Capture-MS

Homo sapiens

UBE2H

7328

Affinity Capture-MS

Homo sapiens

RIT1

6016

Negative Genetic

Homo sapiens

ZMYND19

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

SLIRP

81892

Proximity Label-MS

Homo sapiens

H1FNT

Affinity Capture-MS

Homo sapiens

MRPL48

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

SPRTN

Affinity Capture-MS

Homo sapiens

ZNF346

Affinity Capture-MS

Homo sapiens

COX15

1355

Proximity Label-MS

Homo sapiens

MRPL33

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

TRUB2

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

POLG

Affinity Capture-MS

Homo sapiens

MTG2

Proximity Label-MS

Homo sapiens

NGRN

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

CHCHD1

Proximity Label-MS

Homo sapiens

MRPL10

124995

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

MRPL27

51264

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

CSNK2A1

1457

Biochemical Activity

Homo sapiens

XRN2

22803

Two-hybrid

Homo sapiens

CAND1

55832

Affinity Capture-MS

Homo sapiens

HNRNPR

10236

Co-fractionation

Homo sapiens

RPUSD4

84881

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

MRPL49

740

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

WDR26

80232

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

ZSWIM8

23053

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

DNAJC15

Proximity Label-MS

Homo sapiens

MTRF1

Proximity Label-MS

Homo sapiens

GFM2

84340

Proximity Label-MS

Homo sapiens

CCDC90B

Proximity Label-MS

Homo sapiens

APEX1

328

Affinity Capture-RNA

Homo sapiens

RPS18

6222

Co-fractionation

Homo sapiens

KRTAP4-12

Two-hybrid

Homo sapiens

MRPL20

55052

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

MCU

90550

Proximity Label-MS

Homo sapiens

TFAM

7019

Proximity Label-MS

Homo sapiens

PMPCA

23203

Proximity Label-MS

Homo sapiens

RANBP10

57610

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

MRPL23

6150

Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

Ints4

Affinity Capture-MS

Mus musculus

PRC1

9055

Affinity Capture-MS

Homo sapiens

HINT2

84681

Proximity Label-MS

Homo sapiens

DUSP11

Affinity Capture-MS

Homo sapiens

MRPL12

6182

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

SLC25A12

8604

Proximity Label-MS

Homo sapiens

KLF15

Affinity Capture-MS

Homo sapiens

MRPL57

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

AMER1

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

MRPS26

64949

Proximity Label-MS

Homo sapiens

SURF1

Proximity Label-MS

Homo sapiens

TRA2A

29896

Affinity Capture-MS

Homo sapiens

PTCD1

26024

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

EXD2

Proximity Label-MS

Homo sapiens

RC3H1

149041

Affinity Capture-MS

Homo sapiens

TEX19

Affinity Capture-MS

Homo sapiens

MRPL39

54148

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

KLF4

Affinity Capture-MS

Homo sapiens

EXOSC6

118460

Two-hybrid

Homo sapiens

SPATA5L1

79029

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

MECP2

4204

Affinity Capture-MS

Homo sapiens

BTRC

8945

Affinity Capture-MS

Homo sapiens

PMPCB

9512

Proximity Label-MS

Homo sapiens

TACO1

Proximity Label-MS

Homo sapiens

FASTKD2

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

VWA8

23078

Proximity Label-MS

Homo sapiens

MRPL47

57129

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

HSPD1

3329

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

MTERF3

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

KIF14

9928

Affinity Capture-MS

Homo sapiens

CINP

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

LIN28A

Affinity Capture-MS

Homo sapiens

MDH2

4191

Proximity Label-MS

Homo sapiens

KLF16

Affinity Capture-MS

Homo sapiens

L1TD1

Affinity Capture-MS

Homo sapiens

MRPL13

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

CLK2

1196

Two-hybrid

Homo sapiens

MRPL32

64983

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

C6orf203

Proximity Label-MS

Homo sapiens

MKLN1

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

MRPL17

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

RC3H2

Affinity Capture-MS

Homo sapiens

FASTKD5

Proximity Label-MS

Homo sapiens

MRPL45

84311

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

Cenpe

Affinity Capture-MS

Mus musculus

MRPL30

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

RBFOX2

23543

Two-hybrid

Homo sapiens

MALSU1

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

ARMC8

25852

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

MRPL14

64928

Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens

YBX2

51087

Affinity Capture-MS

Homo sapiens

RPL19

6143

Affinity Capture-MS

Homo sapiens

YPEL5

51646

Affinity Capture-MS

Homo sapiens

TUFM

7284

Co-fractionation		Homo sapiens
Proximity Label-MS		Homo sapiens

ARHGEF1

9138

Affinity Capture-MS

Homo sapiens

HSCB

150274

Proximity Label-MS

Homo sapiens

UBR5

51366

Affinity Capture-MS

Homo sapiens

MRPL37

51253

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

GID8

54994

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

MRPL51

51258

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

100

AARS2

Affinity Capture-MS

Homo sapiens

101

LOC100132735

Protein-RNA

Homo sapiens

102

CCDC109B

55013

Proximity Label-MS

Homo sapiens

103

TBRG4

9238

Proximity Label-MS

Homo sapiens

104

CYC1

1537

Co-fractionation

Homo sapiens

105

MRPL3

Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

106

CSNK1E

1454

Affinity Capture-MS

Homo sapiens

107

MTFMT

Proximity Label-MS

Homo sapiens

108

FAM83H

286077

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

109

MRPL11

65003

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

110

MTRF1L

Proximity Label-MS

Homo sapiens

111

TMEM70

Proximity Label-MS

Homo sapiens

112

CYLD

Affinity Capture-MS

Homo sapiens

113

RMND5A

64795

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

114

MRPL2

51069

Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

115

GNPNAT1

64841

Affinity Capture-MS

Homo sapiens

116

Pdlim5

56376

Affinity Capture-MS

Mus musculus

117

MRPL41

64975

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

118

Brwd3

Affinity Capture-MS

Mus musculus

119

OXA1L

Affinity Capture-MS

Homo sapiens

120

HNRNPD

3184

Affinity Capture-MS

Homo sapiens

121

MRPL44

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

122

MRPL40

64976

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

123

WBSCR16

Affinity Capture-MS

Homo sapiens

124

ACKR3

57007

Affinity Capture-MS

Homo sapiens

125

MRPL21

219927

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

126

MRRF

Proximity Label-MS

Homo sapiens

127

ABT1

29777

Affinity Capture-MS

Homo sapiens

128

MRPS12

Proximity Label-MS

Homo sapiens

129

MTIF2

4528

Proximity Label-MS

Homo sapiens

130

RPS2

6187

Co-fractionation

Homo sapiens

131

MRPL24

Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

132

MRPL35

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

133

YBX1

4904

Affinity Capture-MS

Homo sapiens

134

MTIF3

Proximity Label-MS

Homo sapiens

135

MRPL9

65005

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

136

MRPL16

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

137

RPL37

6167

Affinity Capture-MS

Homo sapiens

138

GLS

2744

Affinity Capture-MS

Homo sapiens

139

CUL3

8452

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

140

RPS8

6202

Affinity Capture-MS

Homo sapiens

141

SRSF5

6430

Affinity Capture-MS

Homo sapiens

142

GADD45GIP1

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

143

HNRNPA1

3178

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

144

MRPL50

54534

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

145

NHP2

55651

Affinity Capture-MS

Homo sapiens

146

C17orf80

55028

Proximity Label-MS

Homo sapiens

147

HTRA2

27429

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

148

MRPL15

29088

Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

149

C12orf65

Proximity Label-MS

Homo sapiens

150

MYCN

Affinity Capture-MS

Homo sapiens

151

PRR3

Affinity Capture-MS

Homo sapiens

152

MRPL52

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

153

PCBP1

5093

Affinity Capture-MS

Homo sapiens

154

MRPL19

9801

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

155

MTG1

Proximity Label-MS

Homo sapiens

156

MRPL38

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

157

MYC

Affinity Capture-MS

Homo sapiens

158

RPA3

6119

Proximity Label-MS

Homo sapiens

159

DHX30

22907

Proximity Label-MS

Homo sapiens

160

SAV1

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

161

TSFM

10102

Proximity Label-MS

Homo sapiens

162

RPL27A

6157

Affinity Capture-MS

Homo sapiens

163

ACAD9

28976

Proximity Label-MS

Homo sapiens

164

SRSF10

10772

Affinity Capture-MS

Homo sapiens

165

PDPR

55066

Affinity Capture-MS

Homo sapiens

166

EIF2B1

1967

Two-hybrid

Homo sapiens

167

CD55

1604

Co-fractionation

Homo sapiens

168

MARS2

92935

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

169

MRPL34

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

170

HIST1H1T

3010

Affinity Capture-MS

Homo sapiens

171

METTL15

Proximity Label-MS

Homo sapiens

172

MCUR1

63933

Proximity Label-MS

Homo sapiens

173

RBMS2

5939

Affinity Capture-MS

Homo sapiens

174

SOX2

Affinity Capture-MS

Homo sapiens

175

TCF25

22980

Affinity Capture-MS

Homo sapiens

176

FAM120A

23196

Affinity Capture-MS

Homo sapiens

177

CLPP

8192

Proximity Label-MS

Homo sapiens

178

DNAJC28

Proximity Label-MS

Homo sapiens

179

1431

Proximity Label-MS

Homo sapiens

180

MRPL42

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

181

PLEKHA4

57664

Affinity Capture-MS

Homo sapiens

182

FBXW11

Affinity Capture-MS

Homo sapiens

183

MAGEF1

Affinity Capture-MS

Homo sapiens

184

AUH

549

Proximity Label-MS

Homo sapiens

185

ILF3

3609

Co-fractionation

Homo sapiens

186

MRPL22

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

187

DNAJC19

131118

Proximity Label-MS

Homo sapiens

188

MCAT

27349

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

189

RNPS1

10921

Affinity Capture-MS

Homo sapiens

190

GTPBP6

Affinity Capture-MS

Homo sapiens

191

ICT1

3396

Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens
Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

192

APOBEC3D

Affinity Capture-MS

Homo sapiens

193

LONP1

9361

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

194

SRSF9

8683

Affinity Capture-MS

Homo sapiens

195

LRPPRC

10128

Proximity Label-MS

Homo sapiens

196

MRPL53

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

197

MRPL43

84545

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

198

RMND5B

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

199

DNAJA3

9093

Proximity Label-MS

Homo sapiens

200

MRPL1

Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

201

MSI2

124540

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

202

TRA2B

6434

Affinity Capture-MS

Homo sapiens

203

C21orf33

Proximity Label-MS

Homo sapiens

204

MRPL18

29074

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

205

SSBP1

6742

Proximity Label-MS

Homo sapiens

206

YARS2

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

207

PCNA

5111

Affinity Capture-MS

Homo sapiens

208

MRPS30

10884

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

209

FASTKD3

Proximity Label-MS

Homo sapiens

210

GID4

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

211

NEIL1

Affinity Capture-MS

Homo sapiens

212

SRSF3

6428

Affinity Capture-MS

Homo sapiens

213

GFM1

85476

Proximity Label-MS

Homo sapiens

214

RANBP9

10048

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

215

RNMTL1

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

216

TRIM23

373

Two-hybrid

Homo sapiens

217

TEFM

Proximity Label-MS

Homo sapiens

218

MRPL46

Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

219

Samhd1

56045

Affinity Capture-MS

Mus musculus

220

TATDN2

Affinity Capture-MS

Homo sapiens

221

RPUSD3

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

222

RPL8

6132

Co-fractionation

Homo sapiens

223

GRSF1

2926

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

224

C1QBP

708

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

225

KRAS

3845

Negative Genetic

Homo sapiens

226

HNRNPU

3192

Affinity Capture-MS

Homo sapiens

227

C9orf72

Affinity Capture-MS

Homo sapiens

228

MRPL55

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

229

METTL17

Proximity Label-MS

Homo sapiens

230

NEFL

4747

Affinity Capture-MS

Homo sapiens

231

MRPL28

10573

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

232

MRPS18A

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

233

DDX28

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

234

RPL17

6139

Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens

235

MAEA

10296

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

View the network

Pathways in which MRPL4 is involved

Pathway	Evidence	Source
Metabolism of proteins	TAS	Reactome
Metabolism of proteins	IEA	Reactome
Mitochondrial translation	TAS	Reactome
Mitochondrial translation	IEA	Reactome
Mitochondrial translation elongation	TAS	Reactome
Mitochondrial translation elongation	IEA	Reactome
Mitochondrial translation initiation	IEA	Reactome
Mitochondrial translation termination	TAS	Reactome
Translation	TAS	Reactome
Translation	IEA	Reactome

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here