ExoCarta: Gene summary

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Gene description for MTIF2
Gene name	mitochondrial translational initiation factor 2
Gene symbol	MTIF2
Other names/aliases	-
Species	Homo sapiens
Database cross references - MTIF2
ExoCarta	ExoCarta_4528
Vesiclepedia	VP_4528
Entrez Gene	4528
HGNC	7441
MIM	603766
UniProt	P46199
MTIF2 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells	36408942
Bone marrow mesenchymal stem cells	36408942
Bone marrow mesenchymal stem cells	36408942
Bone marrow mesenchymal stem cells	36408942

Gene ontology annotations for MTIF2

Molecular Function
	RNA binding	GO:0003723	HDA
	translation initiation factor activity	GO:0003743	IBA
	GTPase activity	GO:0003924	IEA
	GTP binding	GO:0005525	IEA
	translation factor activity, RNA binding	GO:0008135	ISS
	ribosomal small subunit binding	GO:0043024	ISS
Biological Process
	regulation of translational initiation	GO:0006446	TAS
	ribosome disassembly	GO:0032790	ISS
	mitochondrial translational initiation	GO:0070124	IBA
	mitochondrial translational initiation	GO:0070124	ISS
Subcellular Localization
	nucleoplasm	GO:0005654	IDA
	cytoplasm	GO:0005737	IBA
	mitochondrion	GO:0005739	HTP
	mitochondrion	GO:0005739	IBA
	mitochondrion	GO:0005739	IDA

Experiment description of studies that identified MTIF2 in exosomes

Experiment ID

489

MISEV standards
✔ EM	Biophysical techniques
✔ Cd9\|Cd81\|Cd63\|Gapdh\|Sdcbp\|Lamp1\|Aqp1\|Rab5a\|Icam1\|Cd82\|Itga2b\|Tsg101\|Lamp2\|Rab35\|Flot1\|Flot2\|Cd151\|Rab5b\|Tfrc\|Uchl1	Enriched markers
✔ Canx	Negative markers
✔ NTA	Particle analysis

Identified molecule

Protein

Identification method

Mass spectrometry

PubMed ID

36408942

Organism

Rattus norvegicus

Experiment description

Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells

Authors

"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."

Journal name

Proteomics

Publication year

2023

Sample

Bone marrow mesenchymal stem cells

Sample name

BMSC - Passage 6

Isolation/purification methods

Differential centrifugation
Filtration
Ultracentrifugation

Flotation density

Molecules identified in the study

Protein

Methods used in the study

Western blotting
Mass spectometry

Experiment ID

490

MISEV standards
✔ EM	Biophysical techniques
✔ Cd9\|Cd81\|Cd63\|Gapdh\|Sdcbp\|Lamp1\|Aqp1\|Rab5a\|Icam1\|Cd82\|Itga2b\|Tsg101\|Lamp2\|Rab35\|Flot1\|Flot2\|Cd151\|Rab5b\|Tfrc\|Uchl1	Enriched markers
✔ Canx	Negative markers
✔ NTA	Particle analysis

Identified molecule

Protein

Identification method

Mass spectrometry

PubMed ID

36408942

Organism

Rattus norvegicus

Experiment description

Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells

Authors

"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."

Journal name

Proteomics

Publication year

2023

Sample

Bone marrow mesenchymal stem cells

Sample name

BMSC - Passage 7

Isolation/purification methods

Differential centrifugation
Filtration
Ultracentrifugation

Flotation density

Molecules identified in the study

Protein

Methods used in the study

Western blotting
Mass spectometry

Experiment ID

491

MISEV standards
✔ EM	Biophysical techniques
✔ Cd9\|Cd81\|Cd63\|Gapdh\|Sdcbp\|Lamp1\|Aqp1\|Rab5a\|Icam1\|Cd82\|Itga2b\|Tsg101\|Lamp2\|Rab35\|Flot1\|Flot2\|Cd151\|Rab5b\|Tfrc\|Uchl1	Enriched markers
✔ Canx	Negative markers
✔ NTA	Particle analysis

Identified molecule

Protein

Identification method

Mass spectrometry

PubMed ID

36408942

Organism

Rattus norvegicus

Experiment description

Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells

Authors

"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."

Journal name

Proteomics

Publication year

2023

Sample

Bone marrow mesenchymal stem cells

Sample name

BMSC - Passage 8

Isolation/purification methods

Differential centrifugation
Filtration
Ultracentrifugation

Flotation density

Molecules identified in the study

Protein

Methods used in the study

Western blotting
Mass spectometry

Experiment ID

492

MISEV standards
✔ EM	Biophysical techniques
✔ Cd9\|Cd81\|Cd63\|Gapdh\|Sdcbp\|Lamp1\|Aqp1\|Rab5a\|Icam1\|Cd82\|Itga2b\|Tsg101\|Lamp2\|Rab35\|Flot1\|Flot2\|Cd151\|Rab5b\|Tfrc\|Uchl1	Enriched markers
✔ Canx	Negative markers
✔ NTA	Particle analysis

Identified molecule

Protein

Identification method

Mass spectrometry

PubMed ID

36408942

Organism

Rattus norvegicus

Experiment description

Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells

Authors

"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."

Journal name

Proteomics

Publication year

2023

Sample

Bone marrow mesenchymal stem cells

Sample name

BMSC - Passage 9

Isolation/purification methods

Differential centrifugation
Filtration
Ultracentrifugation

Flotation density

Molecules identified in the study

Protein

Methods used in the study

Western blotting
Mass spectometry

Protein-protein interactions for MTIF2

Protein Interactor

ExoCarta ID

Identification method

PubMed

Species

GTPBP3

Proximity Label-MS

Homo sapiens

COX5A

9377

Proximity Label-MS

Homo sapiens

MRPS27

23107

Proximity Label-MS

Homo sapiens

AFG3L2

10939

Proximity Label-MS

Homo sapiens

PYCR2

29920

Proximity Label-MS

Homo sapiens

PRKAA1

5562

Affinity Capture-MS

Homo sapiens

C7orf55-LUC7L2

Proximity Label-MS

Homo sapiens

UQCRFS1

7386

Affinity Capture-MS

Homo sapiens

IARS2

55699

Proximity Label-MS

Homo sapiens

MRPL48

Proximity Label-MS

Homo sapiens

POLR2H

5437

Co-fractionation

Homo sapiens

THEM4

Proximity Label-MS

Homo sapiens

ATP5J2-PTCD1

Proximity Label-MS

Homo sapiens

SDHA

6389

Proximity Label-MS

Homo sapiens

NDUFS1

4719

Proximity Label-MS

Homo sapiens

MRPS30

10884

Proximity Label-MS

Homo sapiens

EIF2S3

1968

Co-fractionation

Homo sapiens

MRPL17

Proximity Label-MS

Homo sapiens

DLST

1743

Proximity Label-MS

Homo sapiens

ARHGEF26

26084

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

OXLD1

Affinity Capture-MS

Homo sapiens

GTPBP10

Proximity Label-MS

Homo sapiens

PDK3

5165

Proximity Label-MS

Homo sapiens

MTPAP

55149

Proximity Label-MS

Homo sapiens

TRUB2

Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

POLG

Proximity Label-MS

Homo sapiens

MTG2

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

NGRN

Proximity Label-MS

Homo sapiens

SLC2A1

6513

Proximity Label-MS

Homo sapiens

NUDT6

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

CDK5RAP1

Proximity Label-MS

Homo sapiens

ETFB

2109

Proximity Label-MS

Homo sapiens

CNP

1267

Proximity Label-MS

Homo sapiens

NDUFS7

374291

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

MRPL50

54534

Proximity Label-MS

Homo sapiens

BPNT1

10380

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

GATB

Proximity Label-MS

Homo sapiens

RPUSD4

84881

Proximity Label-MS

Homo sapiens

PDHB

5162

Proximity Label-MS

Homo sapiens

MRPL49

740

Proximity Label-MS

Homo sapiens

IQGAP2

10788

Co-fractionation

Homo sapiens

MRPL23

6150

Proximity Label-MS

Homo sapiens

MRPL44

Proximity Label-MS

Homo sapiens

MTRF1

Proximity Label-MS

Homo sapiens

CCDC90B

Proximity Label-MS

Homo sapiens

ATP5L

10632

Proximity Label-MS

Homo sapiens

CARS2

79587

Proximity Label-MS

Homo sapiens

LRPPRC

10128

Proximity Label-MS		Homo sapiens
Co-fractionation		Homo sapiens
Proximity Label-MS		Homo sapiens

NFKB1

4790

Co-fractionation

Homo sapiens

MRPS35

60488

Proximity Label-MS

Homo sapiens

NOA1

Proximity Label-MS

Homo sapiens

NNT

23530

Proximity Label-MS

Homo sapiens

ATP5D

513

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

MRPL20

55052

Proximity Label-MS

Homo sapiens

NDUFS3

4722

Proximity Label-MS

Homo sapiens

MRPS34

65993

Proximity Label-MS

Homo sapiens

CRYZ

1429

Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

TFAM

7019

Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

PDK1

5163

Proximity Label-MS

Homo sapiens

PMPCA

23203

Proximity Label-MS

Homo sapiens

SARS2

54938

Proximity Label-MS

Homo sapiens

SUPV3L1

6832

Proximity Label-MS

Homo sapiens

NDUFA7

4701

Proximity Label-MS

Homo sapiens

HARS2

23438

Proximity Label-MS

Homo sapiens

MRPS36

92259

Proximity Label-MS

Homo sapiens

MRPS5

64969

Proximity Label-MS

Homo sapiens

YARS2

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

HINT2

84681

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

MRPS23

51649

Proximity Label-MS

Homo sapiens

MRPS24

64951

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

MRPL12

6182

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

PDE12

201626

Proximity Label-MS

Homo sapiens

ETFA

2108

Proximity Label-MS

Homo sapiens

POLR1E

Co-fractionation

Homo sapiens

FTSJ2

29960

Affinity Capture-MS

Homo sapiens

C21orf33

Proximity Label-MS

Homo sapiens

MRPL57

Proximity Label-MS

Homo sapiens

BCKDK

10295

Proximity Label-MS

Homo sapiens

MRPS26

64949

Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

SURF1

Proximity Label-MS

Homo sapiens

POLRMT

5442

Proximity Label-MS

Homo sapiens

PTCD1

26024

Affinity Capture-MS

Homo sapiens

ALK

238

Affinity Capture-MS

Homo sapiens

EXD2

Proximity Label-MS

Homo sapiens

ERAL1

Proximity Label-MS

Homo sapiens

MRPL39

54148

Proximity Label-MS

Homo sapiens

NDUFAF1

Proximity Label-MS

Homo sapiens

NDUFAB1

4706

Proximity Label-MS

Homo sapiens

MRPS7

51081

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

NT5DC2

64943

Proximity Label-MS

Homo sapiens

BCS1L

617

Proximity Label-MS

Homo sapiens

CUL1

8454

Co-fractionation

Homo sapiens

PMPCB

9512

Proximity Label-MS

Homo sapiens

MRPL4

51073

Proximity Label-MS

Homo sapiens

FASTKD2

Proximity Label-MS

Homo sapiens

NME4

4833

Proximity Label-MS

Homo sapiens

NDUFA6

Proximity Label-MS

Homo sapiens

METTL2A

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

MRPL47

57129

Proximity Label-MS

Homo sapiens

100

HSPD1

3329

Proximity Label-MS

Homo sapiens

101

MTERF3

Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

102

MTO1

Proximity Label-MS

Homo sapiens

103

MRPS15

Proximity Label-MS

Homo sapiens

104

MDH2

4191

Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

105

AGO2

27161

Affinity Capture-MS

Homo sapiens

106

STOML2

30968

Proximity Label-MS

Homo sapiens

107

GARS

2617

Proximity Label-MS

Homo sapiens

108

ALAS1

Proximity Label-MS

Homo sapiens

109

MRPS25

64432

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

110

RELA

5970

Co-fractionation

Homo sapiens

111

MRPL32

64983

Proximity Label-MS

Homo sapiens

112

OGDH

4967

Proximity Label-MS

Homo sapiens

113

MRPS33

Proximity Label-MS

Homo sapiens

114

C6orf203

Proximity Label-MS

Homo sapiens

115

NDUFS4

4724

Proximity Label-MS

Homo sapiens

116

FASTKD5

Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

117

MRPL45

84311

Proximity Label-MS

Homo sapiens

118

FGA

2243

Proximity Label-MS

Homo sapiens

119

MALSU1

Affinity Capture-MS

Homo sapiens

120

ME2

4200

Proximity Label-MS

Homo sapiens

121

ACOT2

10965

Proximity Label-MS

Homo sapiens

122

TARS2

80222

Proximity Label-MS

Homo sapiens

123

AMACR

23600

Affinity Capture-MS

Homo sapiens

124

ATPAF1

Proximity Label-MS

Homo sapiens

125

TUFM

7284

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

126

LETM1

3954

Proximity Label-MS

Homo sapiens

127

DHRS2

10202

Affinity Capture-MS

Homo sapiens

128

C22orf15

Affinity Capture-MS

Homo sapiens

129

PTCD3

55037

Proximity Label-MS

Homo sapiens

130

HSCB

150274

Proximity Label-MS

Homo sapiens

131

DHRS4L2

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

132

NDUFAF5

Proximity Label-MS

Homo sapiens

133

NDUFS8

4728

Proximity Label-MS

Homo sapiens

134

MMAB

326625

Proximity Label-MS

Homo sapiens

135

WARS2

Proximity Label-MS

Homo sapiens

136

DIRAS3

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

137

MRPS18B

28973

Proximity Label-MS

Homo sapiens

138

MRPS6

Proximity Label-MS

Homo sapiens

139

PDHX

8050

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

140

CCDC109B

55013

Proximity Label-MS

Homo sapiens

141

VWA8

23078

Proximity Label-MS

Homo sapiens

142

PAM16

Proximity Label-MS

Homo sapiens

143

POLDIP2

26073

Proximity Label-MS

Homo sapiens

144

GFM1

85476

Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

145

C10orf2

56652

Proximity Label-MS

Homo sapiens

146

KIAA0391

Proximity Label-MS

Homo sapiens

147

PPA2

27068

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

148

LYPLAL1

127018

Proximity Label-MS

Homo sapiens

149

LYRM4

57128

Proximity Label-MS

Homo sapiens

150

DBT

1629

Proximity Label-MS

Homo sapiens

151

AARS2

Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

152

MRPL11

65003

Proximity Label-MS

Homo sapiens

153

MTRF1L

Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

154

NFKB2

4791

Co-fractionation

Homo sapiens

155

RASL10B

Affinity Capture-MS

Homo sapiens

156

NDUFV3

4731

Proximity Label-MS

Homo sapiens

157

TMEM70

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

158

MRPS14

Proximity Label-MS

Homo sapiens

159

ATP5B

506

Proximity Label-MS

Homo sapiens

160

ABCB7

Proximity Label-MS

Homo sapiens

161

COX4I1

1327

Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

162

CD3EAP

Co-fractionation

Homo sapiens

163

NDUFV1

4723

Proximity Label-MS

Homo sapiens

164

OXA1L

Proximity Label-MS

Homo sapiens

165

HNRNPDL

9987

Proximity Label-MS

Homo sapiens

166

PPIF

10105

Proximity Label-MS

Homo sapiens

167

MRPL14

64928

Proximity Label-MS

Homo sapiens

168

MRM1

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

169

ACOT1

641371

Proximity Label-MS

Homo sapiens

170

ACAT1

Proximity Label-MS

Homo sapiens

171

OTC

5009

Proximity Label-MS

Homo sapiens

172

MRPL40

64976

Proximity Label-MS

Homo sapiens

173

OAT

4942

Proximity Label-MS

Homo sapiens

174

MRPL21

219927

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

175

MRRF

Proximity Label-MS

Homo sapiens

176

AIFM1

9131

Proximity Label-MS

Homo sapiens

177

MRPS12

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

178

MRPL10

124995

Proximity Label-MS

Homo sapiens

179

DAP3

7818

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

180

TRMT10C

54931

Proximity Label-MS

Homo sapiens

181

PNPT1

87178

Proximity Label-MS

Homo sapiens

182

MRPL24

Proximity Label-MS

Homo sapiens

183

AK4

205

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

184

EIF2S1

1965

Co-fractionation

Homo sapiens

185

MRPS11

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

186

MTIF3

Proximity Label-MS

Homo sapiens

187

HNRNPL

3191

Proximity Label-MS

Homo sapiens

188

RTN4IP1

Proximity Label-MS

Homo sapiens

189

ATP5H

10476

Proximity Label-MS

Homo sapiens

190

GCDH

2639

Proximity Label-MS

Homo sapiens

191

MRPL27

51264

Proximity Label-MS

Homo sapiens

192

MRPL9

65005

Proximity Label-MS

Homo sapiens

193

NUDT16

131870

Affinity Capture-MS

Homo sapiens

194

MRPL16

Proximity Label-MS

Homo sapiens

195

SLC30A9

10463

Proximity Label-MS

Homo sapiens

196

NFS1

9054

Proximity Label-MS

Homo sapiens

197

ATP5F1

515

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

198

MRPL42

Proximity Label-MS

Homo sapiens

199

PYCR1

5831

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

200

FAHD1

81889

Affinity Capture-MS

Homo sapiens

201

HSD17B10

3028

Proximity Label-MS

Homo sapiens

202

ELAC2

60528

Proximity Label-MS

Homo sapiens

203

GADD45GIP1

Proximity Label-MS

Homo sapiens

204

DHX30

22907

Proximity Label-MS

Homo sapiens

205

VARS2

Proximity Label-MS

Homo sapiens

206

PUS1

80324

Proximity Label-MS

Homo sapiens

207

ECHS1

1892

Proximity Label-MS

Homo sapiens

208

GLUD1

2746

Proximity Label-MS

Homo sapiens

209

MRPL15

29088

Proximity Label-MS

Homo sapiens

210

ECI2

10455

Proximity Label-MS

Homo sapiens

211

HADHA

3030

Proximity Label-MS

Homo sapiens

212

MUT

4594

Proximity Label-MS

Homo sapiens

213

ATP5O

539

Proximity Label-MS

Homo sapiens

214

MRPL19

9801

Proximity Label-MS

Homo sapiens

215

MTG1

Proximity Label-MS

Homo sapiens

216

MRPL38

Proximity Label-MS

Homo sapiens

217

NDUFA2

4695

Proximity Label-MS

Homo sapiens

218

TACO1

Proximity Label-MS

Homo sapiens

219

MRPL37

51253

Proximity Label-MS

Homo sapiens

220

EGFR

1956

Negative Genetic

Homo sapiens

221

CBR4

Affinity Capture-MS

Homo sapiens

222

LDHAL6B

92483

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

223

HSDL2

84263

Proximity Label-MS

Homo sapiens

224

NUDT19

390916

Proximity Label-MS

Homo sapiens

225

MRPL3

Proximity Label-MS

Homo sapiens

226

POLR1A

Co-fractionation

Homo sapiens

227

ACAD9

28976

Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

228

TSC22D2

9819

Two-hybrid

Homo sapiens

229

FOXRED1

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

230

MTHFD2

10797

Proximity Label-MS

Homo sapiens

231

PDPR

55066

Proximity Label-MS

Homo sapiens

232

NDUFA9

4704

Proximity Label-MS

Homo sapiens

233

CLPB

81570

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

234

NDUFA10

4705

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

235

NDUFA12

55967

Proximity Label-MS

Homo sapiens

236

MRPS17

51373

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

237

HSPA9

3313

Proximity Label-MS

Homo sapiens

238

DLAT

1737

Proximity Label-MS

Homo sapiens

239

CLPX

10845

Proximity Label-MS

Homo sapiens

240

METTL15

Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

241

ZC3H3

Affinity Capture-MS

Homo sapiens

242

KPNA2

3838

Co-fractionation

Homo sapiens

243

PFDN5

5204

Affinity Capture-MS

Homo sapiens

244

MCUR1

63933

Proximity Label-MS

Homo sapiens

245

NUBPL

80224

Proximity Label-MS

Homo sapiens

246

NDUFS2

4720

Proximity Label-MS

Homo sapiens

247

MRPL55

Proximity Label-MS

Homo sapiens

248

MTHFD1L

25902

Proximity Label-MS

Homo sapiens

249

NDUFA5

4698

Proximity Label-MS

Homo sapiens

250

NDUFAF2

Proximity Label-MS

Homo sapiens

251

NIPSNAP3A

Affinity Capture-MS

Homo sapiens

252

CLPP

8192

Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

253

DNAJC28

Proximity Label-MS

Homo sapiens

254

1431

Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

255

GLS

2744

Proximity Label-MS

Homo sapiens

256

NFKBIB

Co-fractionation

Homo sapiens

257

C17orf80

55028

Proximity Label-MS

Homo sapiens

258

TSFM

10102

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

259

AUH

549

Proximity Label-MS

Homo sapiens

260

PARP1

142

Proximity Label-MS

Homo sapiens

261

MRPS9

64965

Proximity Label-MS

Homo sapiens

262

MRPL22

Proximity Label-MS

Homo sapiens

263

ATP5J

522

Proximity Label-MS

Homo sapiens

264

MRPS2

51116

Proximity Label-MS

Homo sapiens

265

COQ5

Proximity Label-MS

Homo sapiens

266

UQCC1

55245

Proximity Label-MS

Homo sapiens

267

GTPBP6

Proximity Label-MS

Homo sapiens

268

ICT1

3396

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

269

MRPS28

Proximity Label-MS

Homo sapiens

270

PNPLA8

50640

Proximity Label-MS

Homo sapiens

271

LARS2

23395

Proximity Label-MS

Homo sapiens

272

GRSF1

2926

Proximity Label-MS		Homo sapiens
Co-fractionation		Homo sapiens

273

HADH

3033

Proximity Label-MS

Homo sapiens

274

MRPL53

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

275

MRPL43

84545

Proximity Label-MS

Homo sapiens

276

ACAA2

10449

Affinity Capture-MS

Homo sapiens

277

PDHA1

5160

Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

278

SKP1

6500

Co-fractionation

Homo sapiens

279

MRPL28

10573

Proximity Label-MS

Homo sapiens

280

DNAJA3

9093

Proximity Label-MS

Homo sapiens

281

TRMT61B

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

282

MRPL1

Proximity Label-MS

Homo sapiens

283

HSPB1

3315

Two-hybrid

Homo sapiens

284

GRPEL1

80273

Proximity Label-MS

Homo sapiens

285

COX8A

Proximity Label-MS

Homo sapiens

286

MRPS10

55173

Proximity Label-MS

Homo sapiens

287

SUCLA2

8803

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

288

SHMT2

6472

Proximity Label-MS

Homo sapiens

289

MRPS18C

Proximity Label-MS

Homo sapiens

290

DDX58

23586

Affinity Capture-RNA

Homo sapiens

291

NIPSNAP3B

55335

Affinity Capture-MS

Homo sapiens

292

MRPS21

Proximity Label-MS

Homo sapiens

293

SSBP1

6742

Proximity Label-MS

Homo sapiens

294

GATC

Proximity Label-MS

Homo sapiens

295

HSD17B8

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

296

GUF1

Proximity Label-MS

Homo sapiens

297

FASTKD3

Proximity Label-MS

Homo sapiens

298

NIPSNAP1

8508

Proximity Label-MS

Homo sapiens

299

PREPL

9581

Proximity Label-MS

Homo sapiens

300

LONP1

9361

Proximity Label-MS

Homo sapiens

301

MRPL41

64975

Proximity Label-MS

Homo sapiens

302

TOP3A

Proximity Label-MS

Homo sapiens

303

TBRG4

9238

Proximity Label-MS

Homo sapiens

304

RNMTL1

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

305

MRPL13

Proximity Label-MS

Homo sapiens

306

TEFM

Proximity Label-MS

Homo sapiens

307

TTC39B

158219

Affinity Capture-MS

Homo sapiens

308

IBA57

Proximity Label-MS

Homo sapiens

309

MRPL46

Proximity Label-MS

Homo sapiens

310

RPUSD3

Proximity Label-MS

Homo sapiens

311

MRPS16

Proximity Label-MS

Homo sapiens

312

BRD1

23774

Affinity Capture-MS

Homo sapiens

313

C1QBP

708

Proximity Label-MS

Homo sapiens

314

NDUFAF4

29078

Proximity Label-MS

Homo sapiens

315

QRSL1

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

316

NDUFS6

Proximity Label-MS

Homo sapiens

317

HADHB

3032

Proximity Label-MS

Homo sapiens

318

MRPS31

Proximity Label-MS

Homo sapiens

319

NDUFV2

4729

Proximity Label-MS

Homo sapiens

320

METTL17

Proximity Label-MS

Homo sapiens

321

MRPS22

56945

Proximity Label-MS

Homo sapiens

322

YBEY

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

323

IKBKB

3551

Co-fractionation

Homo sapiens

324

PRDX3

10935

Proximity Label-MS

Homo sapiens

325

TRIM43

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

326

MRPS18A

Proximity Label-MS

Homo sapiens

327

DDX28

Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

328

TIMM44

10469

Proximity Label-MS

Homo sapiens

329

SLIRP

81892

Proximity Label-MS

Homo sapiens

330

ECSIT

51295

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

331

DARS2

55157

Proximity Label-MS

Homo sapiens

332

UGGT1

56886

Co-fractionation

Homo sapiens

333

SHC2

25759

Affinity Capture-MS

Homo sapiens

View the network

Pathways in which MTIF2 is involved

Pathway	Evidence	Source
Metabolism of proteins	IEA	Reactome
Mitochondrial translation	IEA	Reactome
Mitochondrial translation initiation	IEA	Reactome
Translation	IEA	Reactome

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here