Gene description for POLR2H
Gene name polymerase (RNA) II (DNA directed) polypeptide H
Gene symbol POLR2H
Other names/aliases RPABC3
RPB17
RPB8
Species Homo sapiens
 Database cross references - POLR2H
ExoCarta ExoCarta_5437
Vesiclepedia VP_5437
Entrez Gene 5437
HGNC 9195
MIM 606023
UniProt P52434  
 POLR2H identified in exosomes derived from the following tissue/cell type
Endothelial cells 26027894    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocytes 26054723    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Thymus 23844026    
 Gene ontology annotations for POLR2H
Molecular Function
    RNA polymerase I activity GO:0001054 IBA
    RNA polymerase II activity GO:0001055 IBA
    RNA polymerase III activity GO:0001056 IBA
    single-stranded DNA binding GO:0003697 IDA
Biological Process
    transcription by RNA polymerase I GO:0006360 IEA
    transcription by RNA polymerase II GO:0006366 IDA
    transcription by RNA polymerase III GO:0006383 IEA
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 TAS
    RNA polymerase II, core complex GO:0005665 IBA
    RNA polymerase II, core complex GO:0005665 IDA
    RNA polymerase III complex GO:0005666 IBA
    RNA polymerase III complex GO:0005666 IDA
    RNA polymerase I complex GO:0005736 IBA
    RNA polymerase I complex GO:0005736 IDA
    cytosol GO:0005829 TAS
    protein-DNA complex GO:0032993 IDA
 Experiment description of studies that identified POLR2H in exosomes
1
Experiment ID 226
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD9|FLOT1
Enriched markers
✔
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
✘ Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
2
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
3
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
4
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
5
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
6
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
8
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for POLR2H
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CD3EAP  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 POLR2G 5436
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 RIT1 6016
Negative Genetic Homo sapiens
4 GTF2F1 2962
Co-fractionation Homo sapiens
5 RNGTT 8732
Affinity Capture-MS Homo sapiens
6 RASSF8 11228
Affinity Capture-MS Homo sapiens
7 MED17  
Affinity Capture-MS Homo sapiens
8 MED20 9477
Affinity Capture-MS Homo sapiens
9 NFKB1 4790
Co-fractionation Homo sapiens
10 MED6  
Affinity Capture-MS Homo sapiens
11 Atf7ip  
Reconstituted Complex Mus musculus
12 MED29  
Affinity Capture-MS Homo sapiens
13 INTS10  
Affinity Capture-MS Homo sapiens
14 BRCA1 672
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
15 MED13L 23389
Affinity Capture-MS Homo sapiens
16 RECQL5  
Affinity Capture-MS Homo sapiens
17 CSNK2A1 1457
Affinity Capture-MS Homo sapiens
18 KPNA2 3838
Affinity Capture-MS Homo sapiens
19 SCAF4 57466
Affinity Capture-MS Homo sapiens
20 INTS1 26173
Affinity Capture-MS Homo sapiens
21 CDK8 1024
Affinity Capture-MS Homo sapiens
22 URI1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 INTS9 55756
Affinity Capture-MS Homo sapiens
24 LRPPRC 10128
Co-fractionation Homo sapiens
25 TCEB3 6924
Co-localization Homo sapiens
Co-localization Homo sapiens
26 LMO2  
Affinity Capture-MS Homo sapiens
27 MED12L  
Affinity Capture-MS Homo sapiens
28 MED13 9969
Affinity Capture-MS Homo sapiens
29 RUVBL1 8607
Affinity Capture-MS Homo sapiens
30 TRMT1L 81627
Affinity Capture-MS Homo sapiens
31 GTF2F2 2963
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
32 POLR2I 5438
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
33 FBXW7  
Affinity Capture-MS Homo sapiens
34 SRC 6714
Co-localization Homo sapiens
Co-localization Homo sapiens
35 NPM1 4869
Co-fractionation Homo sapiens
36 POLR1E  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 CRCP  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 MED22  
Affinity Capture-MS Homo sapiens
39 INTS6 26512
Affinity Capture-MS Homo sapiens
40 PSMB9 5698
Co-localization Homo sapiens
Co-localization Homo sapiens
41 POLR2C 5432
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
42 NME2 4831
Affinity Capture-MS Homo sapiens
43 METTL18  
Affinity Capture-MS Homo sapiens
44 MED27  
Affinity Capture-MS Homo sapiens
45 POLR2M  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 MYCN  
Affinity Capture-MS Homo sapiens
47 ASNSD1  
Affinity Capture-MS Homo sapiens
48 PFDN6 10471
Affinity Capture-MS Homo sapiens
49 MTIF2 4528
Co-fractionation Homo sapiens
50 USP37  
Proximity Label-MS Homo sapiens
51 MED4 29079
Affinity Capture-MS Homo sapiens
52 GPN3  
Affinity Capture-MS Homo sapiens
53 POLR2K  
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
54 MED1 5469
Affinity Capture-MS Homo sapiens
55 UNK  
Affinity Capture-RNA Homo sapiens
56 DLD 1738
Affinity Capture-MS Homo sapiens
57 MAF1  
Affinity Capture-MS Homo sapiens
58 SCAF1  
Affinity Capture-MS Homo sapiens
59 FOXA1  
Affinity Capture-MS Homo sapiens
60 MED7  
Affinity Capture-MS Homo sapiens
61 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
62 UXT 8409
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 CTDP1 9150
Affinity Capture-MS Homo sapiens
64 POLR3K  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
65 SUPT5H 6829
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
66 MED18  
Affinity Capture-MS Homo sapiens
67 DNMT3A 1788
Affinity Capture-MS Homo sapiens
68 POLR3F  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
69 SNRNP200 23020
Co-fractionation Homo sapiens
70 BDP1  
Affinity Capture-MS Homo sapiens
71 PFDN2 5202
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 BARD1 580
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
73 MED12  
Affinity Capture-MS Homo sapiens
74 SERPINB8 5271
Affinity Capture-MS Homo sapiens
75 CTNNB1 1499
Co-fractionation Homo sapiens
76 MED31  
Affinity Capture-MS Homo sapiens
77 SUPT6H 6830
Affinity Capture-MS Homo sapiens
78 POLR3GL  
Affinity Capture-MS Homo sapiens
79 MED9  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 POLR2B 5431
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 BAG3 9531
Affinity Capture-Luminescence Homo sapiens
82 CD40 958
Affinity Capture-MS Homo sapiens
83 BRF1  
Affinity Capture-MS Homo sapiens
84 CEP57  
Affinity Capture-MS Homo sapiens
85 FANCD2  
Affinity Capture-MS Homo sapiens
86 POLR3A 11128
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
87 POLR2H 5437
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
88 OTUD1 220213
Affinity Capture-MS Homo sapiens
89 UBE2H 7328
Affinity Capture-MS Homo sapiens
90 EPAS1  
Affinity Capture-MS Homo sapiens
91 UBE2W  
Co-crystal Structure Homo sapiens
92 POLR2E 5434
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
93 MED26  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
94 RPRD2  
Affinity Capture-MS Homo sapiens
95 CDK19 23097
Affinity Capture-MS Homo sapiens
96 CUL3 8452
Affinity Capture-MS Homo sapiens
97 MECP2 4204
Affinity Capture-MS Homo sapiens
98 RPRD1A  
Affinity Capture-MS Homo sapiens
99 HSD17B10 3028
Affinity Capture-MS Homo sapiens
100 POLR2D  
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
101 POLR2A 5430
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
102 POLR3E 55718
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
103 RPRD1B 58490
Affinity Capture-MS Homo sapiens
104 UVRAG  
Affinity Capture-MS Homo sapiens
105 MAPK6  
Affinity Capture-MS Homo sapiens
106 MED10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
107 DNMT3B  
Affinity Capture-MS Homo sapiens
108 MYC  
Affinity Capture-MS Homo sapiens
109 PIH1D1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
110 POLR3G  
Affinity Capture-MS Homo sapiens
111 INTS3 65123
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
112 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
113 TOP1 7150
Co-fractionation Homo sapiens
114 RPAP3 79657
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
115 POLR1A  
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
116 SART3 9733
Co-fractionation Homo sapiens
117 DDRGK1 65992
Affinity Capture-MS Homo sapiens
118 RNF2  
Affinity Capture-MS Homo sapiens
119 NFYA 4800
Co-fractionation Homo sapiens
120 NELFB 25920
Affinity Capture-MS Homo sapiens
121 INTS5 80789
Affinity Capture-MS Homo sapiens
122 C9orf72  
Affinity Capture-MS Homo sapiens
123 MED14  
Affinity Capture-MS Homo sapiens
124 XRCC5 7520
Co-fractionation Homo sapiens
125 HUWE1 10075
Affinity Capture-MS Homo sapiens
126 MED11  
Affinity Capture-MS Homo sapiens
127 SNCA 6622
Affinity Capture-MS Homo sapiens
128 MED19  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
129 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
130 POLR2F  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
131 PARP1 142
Co-fractionation Homo sapiens
132 JUP 3728
Co-fractionation Homo sapiens
133 POLR2J  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
134 POLR1B 84172
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
135 GPN1  
Affinity Capture-MS Homo sapiens
136 RUVBL2 10856
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
137 POLR2L 5441
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
138 POLR3C 10623
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
139 POLR1C 9533
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
140 WDR92 116143
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
141 POLR3H  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
142 MED8  
Affinity Capture-MS Homo sapiens
143 CCNC  
Affinity Capture-MS Homo sapiens
144 RPAP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
145 NELFA  
Affinity Capture-MS Homo sapiens
146 GTF2B 2959
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
147 ESR1  
Co-localization Homo sapiens
Co-localization Homo sapiens
148 MED30  
Affinity Capture-MS Homo sapiens
149 ERCC3  
Co-fractionation Homo sapiens
150 ERCC6  
Affinity Capture-MS Homo sapiens
151 MED21  
Affinity Capture-MS Homo sapiens
152 NFYB  
Co-fractionation Homo sapiens
153 ARSF 416
Affinity Capture-MS Homo sapiens
154 PHRF1  
Affinity Capture-MS Homo sapiens
155 POLR3D  
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
156 POLR3B 55703
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
157 GTF2E1 2960
Co-fractionation Homo sapiens
158 XRCC6 2547
Co-fractionation Homo sapiens
159 ZNRD1  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
160 KRAS 3845
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
161 POLR1D 51082
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
162 AR 367
Affinity Capture-MS Homo sapiens
163 IKBKB 3551
Co-fractionation Homo sapiens
164 PDRG1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
165 MED28  
Affinity Capture-MS Homo sapiens
166 GTF2E2  
Co-fractionation Homo sapiens
View the network image/svg+xml
 Pathways in which POLR2H is involved
PathwayEvidenceSource
Abortive elongation of HIV-1 transcript in the absence of Tat IEA Reactome
Activation of anterior HOX genes in hindbrain development during early embryogenesis IEA Reactome
Activation of HOX genes during differentiation IEA Reactome
B-WICH complex positively regulates rRNA expression TAS Reactome
Cell Cycle TAS Reactome
Chromosome Maintenance TAS Reactome
Cytosolic sensors of pathogen-associated DNA TAS Reactome
Developmental Biology IEA Reactome
Disease IEA Reactome
Disease TAS Reactome
Diseases of signal transduction by growth factor receptors and second messengers IEA Reactome
DNA Repair TAS Reactome
Dual incision in TC-NER TAS Reactome
Epigenetic regulation of gene expression IEA Reactome
Epigenetic regulation of gene expression TAS Reactome
ESR-mediated signaling TAS Reactome
Estrogen-dependent gene expression TAS Reactome
FGFR2 alternative splicing TAS Reactome
FGFR2 mutant receptor activation IEA Reactome
Formation of HIV elongation complex in the absence of HIV Tat IEA Reactome
Formation of HIV-1 elongation complex containing HIV-1 Tat TAS Reactome
Formation of HIV-1 elongation complex containing HIV-1 Tat IEA Reactome
Formation of RNA Pol II elongation complex TAS Reactome
Formation of TC-NER Pre-Incision Complex TAS Reactome
Formation of the Early Elongation Complex TAS Reactome
Formation of the HIV-1 Early Elongation Complex IEA Reactome
Gap-filling DNA repair synthesis and ligation in TC-NER TAS Reactome
Gene expression (Transcription) IEA Reactome
Gene expression (Transcription) TAS Reactome
Gene Silencing by RNA IEA Reactome
Gene Silencing by RNA TAS Reactome
Generic Transcription Pathway TAS Reactome
HIV elongation arrest and recovery IEA Reactome
HIV Infection IEA Reactome
HIV Infection TAS Reactome
HIV Life Cycle IEA Reactome
HIV Life Cycle TAS Reactome
HIV Transcription Elongation TAS Reactome
HIV Transcription Elongation IEA Reactome
HIV Transcription Initiation IEA Reactome
Immune System TAS Reactome
Infectious disease IEA Reactome
Infectious disease TAS Reactome
Influenza Infection TAS Reactome
Influenza Viral RNA Transcription and Replication TAS Reactome
Inhibition of DNA recombination at telomere TAS Reactome
Innate Immune System TAS Reactome
Late Phase of HIV Life Cycle IEA Reactome
Late Phase of HIV Life Cycle TAS Reactome
Metabolism of RNA TAS Reactome
MicroRNA (miRNA) biogenesis TAS Reactome
mRNA Capping TAS Reactome
mRNA Splicing TAS Reactome
mRNA Splicing - Major Pathway TAS Reactome
mRNA Splicing - Minor Pathway TAS Reactome
Negative epigenetic regulation of rRNA expression IEA Reactome
NoRC negatively regulates rRNA expression IEA Reactome
Nucleotide Excision Repair TAS Reactome
Pausing and recovery of HIV elongation IEA Reactome
Pausing and recovery of Tat-mediated HIV elongation IEA Reactome
PIWI-interacting RNA (piRNA) biogenesis IEA Reactome
Positive epigenetic regulation of rRNA expression TAS Reactome
Processing of Capped Intron-Containing Pre-mRNA TAS Reactome
RNA Pol II CTD phosphorylation and interaction with CE TAS Reactome
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection IEA Reactome
RNA Polymerase I Promoter Clearance TAS Reactome
RNA Polymerase I Promoter Clearance IEA Reactome
RNA Polymerase I Promoter Escape TAS Reactome
RNA Polymerase I Transcription TAS Reactome
RNA Polymerase I Transcription IEA Reactome
RNA Polymerase I Transcription Initiation TAS Reactome
RNA Polymerase I Transcription Initiation IEA Reactome
RNA Polymerase I Transcription Termination TAS Reactome
RNA Polymerase II HIV Promoter Escape IEA Reactome
RNA Polymerase II Pre-transcription Events TAS Reactome
RNA Polymerase II Promoter Escape TAS Reactome
RNA polymerase II transcribes snRNA genes TAS Reactome
RNA polymerase II transcribes snRNA genes IEA Reactome
RNA Polymerase II Transcription TAS Reactome
RNA Polymerase II Transcription IEA Reactome
RNA Polymerase II Transcription Elongation TAS Reactome
RNA Polymerase II Transcription Initiation TAS Reactome
RNA Polymerase II Transcription Initiation And Promoter Clearance TAS Reactome
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening TAS Reactome
RNA Polymerase III Abortive And Retractive Initiation IEA Reactome
RNA Polymerase III Chain Elongation IEA Reactome
RNA Polymerase III Transcription IEA Reactome
RNA Polymerase III Transcription TAS Reactome
RNA Polymerase III Transcription Initiation IEA Reactome
RNA Polymerase III Transcription Initiation TAS Reactome
RNA Polymerase III Transcription Initiation From Type 1 Promoter IEA Reactome
RNA Polymerase III Transcription Initiation From Type 1 Promoter TAS Reactome
RNA Polymerase III Transcription Initiation From Type 2 Promoter IEA Reactome
RNA Polymerase III Transcription Initiation From Type 2 Promoter TAS Reactome
RNA Polymerase III Transcription Initiation From Type 3 Promoter IEA Reactome
RNA Polymerase III Transcription Initiation From Type 3 Promoter TAS Reactome
RNA Polymerase III Transcription Termination IEA Reactome
Signal Transduction TAS Reactome
Signaling by FGFR TAS Reactome
Signaling by FGFR in disease IEA Reactome
Signaling by FGFR2 TAS Reactome
Signaling by FGFR2 IIIa TM IEA Reactome
Signaling by FGFR2 in disease IEA Reactome
Signaling by Nuclear Receptors TAS Reactome
Signaling by Receptor Tyrosine Kinases TAS Reactome
Tat-mediated elongation of the HIV-1 transcript TAS Reactome
Tat-mediated elongation of the HIV-1 transcript IEA Reactome
Tat-mediated HIV elongation arrest and recovery IEA Reactome
Telomere Maintenance TAS Reactome
TP53 Regulates Transcription of DNA Repair Genes TAS Reactome
Transcription of the HIV genome IEA Reactome
Transcription of the HIV genome TAS Reactome
Transcription-Coupled Nucleotide Excision Repair (TC-NER) TAS Reactome
Transcriptional regulation by small RNAs TAS Reactome
Transcriptional Regulation by TP53 TAS Reactome
Viral Infection Pathways IEA Reactome
Viral Infection Pathways TAS Reactome
Viral Messenger RNA Synthesis TAS Reactome





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