Gene description for LONP1
Gene name lon peptidase 1, mitochondrial
Gene symbol LONP1
Other names/aliases CODASS
LON
LONP
LonHS
PIM1
PRSS15
hLON
Species Homo sapiens
 Database cross references - LONP1
ExoCarta ExoCarta_9361
Vesiclepedia VP_9361
Entrez Gene 9361
HGNC 9479
MIM 605490
UniProt P36776  
 LONP1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
 Gene ontology annotations for LONP1
Molecular Function
    mitochondrial promoter sequence-specific DNA binding GO:0001018 IDA
    single-stranded DNA binding GO:0003697 IBA
    single-stranded RNA binding GO:0003727 IDA
    ATP-dependent peptidase activity GO:0004176 IBA
    ATP-dependent peptidase activity GO:0004176 IDA
    ATP-dependent peptidase activity GO:0004176 IMP
    ATP-dependent peptidase activity GO:0004176 TAS
    serine-type endopeptidase activity GO:0004252 IEA
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IDA
    ATP hydrolysis activity GO:0016887 IEA
    PH domain binding GO:0042731 IEA
    identical protein binding GO:0042802 IPI
    ADP binding GO:0043531 IDA
    insulin receptor substrate binding GO:0043560 IEA
    sequence-specific DNA binding GO:0043565 IDA
    G-quadruplex DNA binding GO:0051880 IDA
    DNA polymerase binding GO:0070182 IPI
Biological Process
    mitochondrial genome maintenance GO:0000002 NAS
    response to hypoxia GO:0001666 IEP
    protein quality control for misfolded or incompletely synthesized proteins GO:0006515 IBA
    mitochondrion organization GO:0007005 IBA
    mitochondrion organization GO:0007005 IMP
    response to hormone GO:0009725 IEA
    response to aluminum ion GO:0010044 IEA
    protein catabolic process GO:0030163 IDA
    mitochondrial DNA metabolic process GO:0032042 NAS
    cellular response to oxidative stress GO:0034599 IC
    cellular response to oxidative stress GO:0034599 IDA
    mitochondrial protein catabolic process GO:0035694 TAS
    negative regulation of insulin receptor signaling pathway GO:0046627 IEA
    chaperone-mediated protein complex assembly GO:0051131 IBA
    proteolysis involved in protein catabolic process GO:0051603 IDA
    oxidation-dependent protein catabolic process GO:0070407 IMP
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IDA
    mitochondrion GO:0005739 IDA
    mitochondrial matrix GO:0005759 IBA
    mitochondrial matrix GO:0005759 IMP
    mitochondrial matrix GO:0005759 TAS
    cytosol GO:0005829 IDA
    membrane GO:0016020 HDA
    mitochondrial nucleoid GO:0042645 IDA
 Experiment description of studies that identified LONP1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
12
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
18
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
20
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
26
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
27
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
31
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for LONP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HIST2H2BE 8349
Affinity Capture-MS Homo sapiens
2 HDAC4  
Affinity Capture-MS Homo sapiens
3 GIGYF1  
Affinity Capture-MS Homo sapiens
4 MTG2  
Proximity Label-MS Homo sapiens
5 MRPL45 84311
Proximity Label-MS Homo sapiens
6 APOE 348
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
7 LOXL4 84171
Two-hybrid Homo sapiens
8 UQCRFS1 7386
Affinity Capture-MS Homo sapiens
9 CCDC90B  
Proximity Label-MS Homo sapiens
10 WDR76  
Affinity Capture-MS Homo sapiens
11 TRMU  
Affinity Capture-MS Homo sapiens
12 PMPCA 23203
Proximity Label-MS Homo sapiens
13 SF3B1 23451
Co-fractionation Homo sapiens
14 FTSJ2 29960
Affinity Capture-MS Homo sapiens
15 KLHL33  
Affinity Capture-MS Homo sapiens
16 CLPB 81570
Proximity Label-MS Homo sapiens
17 SLC25A46 91137
Proximity Label-MS Homo sapiens
18 SLC30A9 10463
Proximity Label-MS Homo sapiens
19 BCS1L 617
Proximity Label-MS Homo sapiens
20 VWA8 23078
Proximity Label-MS Homo sapiens
21 RBM14 10432
Affinity Capture-MS Homo sapiens
22 KIF14 9928
Affinity Capture-MS Homo sapiens
23 NFKBID  
Affinity Capture-MS Homo sapiens
24 TCP1 6950
Co-fractionation Homo sapiens
25 MTMR11  
Affinity Capture-MS Homo sapiens
26 ANKRD17 26057
Affinity Capture-MS Homo sapiens
27 IFIT5 24138
Two-hybrid Homo sapiens
28 UBAC2 337867
Proximity Label-MS Homo sapiens
29 PABPC1 26986
Cross-Linking-MS (XL-MS) Homo sapiens
30 TAF6 6878
Co-fractionation Homo sapiens
31 MRPS6  
Proximity Label-MS Homo sapiens
32 CYC1 1537
Co-fractionation Homo sapiens
33 C1orf158  
Affinity Capture-MS Homo sapiens
34 MTRF1L  
Proximity Label-MS Homo sapiens
35 RASL10B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 VCP 7415
Co-fractionation Homo sapiens
37 SQRDL 58472
Co-fractionation Homo sapiens
38 ANLN 54443
Affinity Capture-MS Homo sapiens
39 SLC2A1 6513
Proximity Label-MS Homo sapiens
40 PNPLA4  
Affinity Capture-MS Homo sapiens
41 MTIF2 4528
Proximity Label-MS Homo sapiens
42 C9orf78 51759
Affinity Capture-MS Homo sapiens
43 SIRT7  
Affinity Capture-MS Homo sapiens
44 PON2 5445
Co-fractionation Homo sapiens
45 NEU4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 HEXA 3073
Co-fractionation Homo sapiens
47 MTG1  
Proximity Label-MS Homo sapiens
48 RPA3 6119
Proximity Label-MS Homo sapiens
49 ESD 2098
Affinity Capture-MS Homo sapiens
50 DLST 1743
Proximity Label-MS Homo sapiens
51 AUH 549
Proximity Label-MS Homo sapiens
52 PSMC5 5705
Co-fractionation Homo sapiens
53 ILK 3611
Affinity Capture-MS Homo sapiens
54 COX2 4513
Proximity Label-MS Homo sapiens
55 PEX3 8504
Proximity Label-MS Homo sapiens
56 GBAS 2631
Affinity Capture-MS Homo sapiens
57 HSPE1 3336
Proximity Label-MS Homo sapiens
58 GLS 2744
Proximity Label-MS Homo sapiens
59 ATP5J 522
Proximity Label-MS Homo sapiens
60 CLPX 10845
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
61 NME4 4833
Proximity Label-MS Homo sapiens
62 CDC37 11140
Two-hybrid Homo sapiens
63 EMC4 51234
Co-fractionation Homo sapiens
64 NGEF  
Affinity Capture-MS Homo sapiens
65 YARS 8565
Proximity Label-MS Homo sapiens
66 DCAF4L2 138009
Affinity Capture-MS Homo sapiens
67 SSBP1 6742
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
68 ATAD3A 55210
Proximity Label-MS Homo sapiens
69 NDUFAF3 25915
Proximity Label-MS Homo sapiens
70 KLHDC8A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 ACOT1 641371
Proximity Label-MS Homo sapiens
72 RAB13 5872
Proximity Label-MS Homo sapiens
73 CLTA 1211
Proximity Label-MS Homo sapiens
74 ACSF3 197322
Affinity Capture-MS Homo sapiens
75 CUL7 9820
Affinity Capture-MS Homo sapiens
76 NFIC 4782
Co-fractionation Homo sapiens
77 PSMC4 5704
Co-fractionation Homo sapiens
78 MAST1  
Two-hybrid Homo sapiens
79 NDUFS6  
Proximity Label-MS Homo sapiens
80 CYP2C8  
Two-hybrid Homo sapiens
81 HNRNPH1 3187
Affinity Capture-MS Homo sapiens
82 COX5A 9377
Proximity Label-MS Homo sapiens
83 AFG3L2 10939
Proximity Label-MS Homo sapiens
84 KIF23 9493
Affinity Capture-MS Homo sapiens
85 MAGEA3  
Affinity Capture-MS Homo sapiens
86 ADRB2  
Affinity Capture-MS Homo sapiens
87 RNMT 8731
Co-fractionation Homo sapiens
88 NDUFA12 55967
Proximity Label-MS Homo sapiens
89 MRPL50 54534
Proximity Label-MS Homo sapiens
90 NDUFS2 4720
Proximity Label-MS Homo sapiens
91 ATP5L 10632
Proximity Label-MS Homo sapiens
92 OGDH 4967
Proximity Label-MS Homo sapiens
93 TLN1 7094
Co-fractionation Homo sapiens
94 PRC1 9055
Affinity Capture-MS Homo sapiens
95 MRPS23 51649
Proximity Label-MS Homo sapiens
96 NDUFA5 4698
Proximity Label-MS Homo sapiens
97 GCAT  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
98 TULP2  
Affinity Capture-MS Homo sapiens
99 GCM1  
Affinity Capture-MS Homo sapiens
100 FBXO11  
Affinity Capture-MS Homo sapiens
101 LACTB 114294
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
102 PHB 5245
Proximity Label-MS Homo sapiens
103 NDUFV3 4731
Proximity Label-MS Homo sapiens
104 MRPS7 51081
Proximity Label-MS Homo sapiens
105 CUL1 8454
Affinity Capture-MS Homo sapiens
106 TACO1  
Proximity Label-MS Homo sapiens
107 PLCB3 5331
Co-fractionation Homo sapiens
108 ARMCX3 51566
Co-fractionation Homo sapiens
109 DYNC1H1 1778
Co-fractionation Homo sapiens
110 CCT2 10576
Co-fractionation Homo sapiens
111 NNT 23530
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
112 KRTAP15-1  
Affinity Capture-MS Homo sapiens
113 RNF32  
Two-hybrid Homo sapiens
114 ATPAF1  
Proximity Label-MS Homo sapiens
115 UQCRC2 7385
Co-fractionation Homo sapiens
116 TEPP  
Affinity Capture-MS Homo sapiens
117 POLDIP2 26073
Proximity Label-MS Homo sapiens
118 TBRG4 9238
Proximity Label-MS Homo sapiens
119 MRPL3  
Proximity Label-MS Homo sapiens
120 AGPS 8540
Co-fractionation Homo sapiens
121 NDUFAF7  
Proximity Label-MS Homo sapiens
122 ATP6V1E1 529
Co-fractionation Homo sapiens
123 ABCB7 22
Proximity Label-MS Homo sapiens
124 FOXF2  
Affinity Capture-MS Homo sapiens
125 MRPL44  
Proximity Label-MS Homo sapiens
126 PSMA3 5684
Affinity Capture-MS Homo sapiens
127 MAP7 9053
Affinity Capture-MS Homo sapiens
128 IBA57  
Proximity Label-MS Homo sapiens
129 NKX2-5  
Affinity Capture-MS Homo sapiens
130 CANX 821
Co-fractionation Homo sapiens
131 ATL3 25923
Affinity Capture-MS Homo sapiens
132 EMC8 10328
Co-fractionation Homo sapiens
133 MRPS35 60488
Proximity Label-MS Homo sapiens
134 RC3H2  
Affinity Capture-MS Homo sapiens
135 RTN4IP1  
Proximity Label-MS Homo sapiens
136 WBSCR16  
Affinity Capture-MS Homo sapiens
137 ATP5F1 515
Proximity Label-MS Homo sapiens
138 EGFR 1956
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
139 HSD17B10 3028
Proximity Label-MS Homo sapiens
140 UPF3A  
Affinity Capture-MS Homo sapiens
141 RPRD1B 58490
Co-fractionation Homo sapiens
142 MYC  
Affinity Capture-MS Homo sapiens
143 ACAD9 28976
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
144 RCN2 5955
Co-fractionation Homo sapiens
145 MRPS17 51373
Proximity Label-MS Homo sapiens
146 NDUFV2 4729
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
147 LMNA 4000
Proximity Label-MS Homo sapiens
148 MCUR1 63933
Proximity Label-MS Homo sapiens
149 NIPSNAP3A  
Affinity Capture-MS Homo sapiens
150 DALRD3  
Affinity Capture-MS Homo sapiens
151 CLPP 8192
Proximity Label-MS Homo sapiens
152 FBXL15  
Affinity Capture-MS Homo sapiens
153 CS 1431
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
154 C17orf80 55028
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
155 BCKDHA 593
Co-fractionation Homo sapiens
156 ATG101  
Affinity Capture-MS Homo sapiens
157 PPP2R2C 5522
Affinity Capture-MS Homo sapiens
158 COX8A  
Proximity Label-MS Homo sapiens
159 SHMT2 6472
Proximity Label-MS Homo sapiens
160 IARS2 55699
Proximity Label-MS Homo sapiens
161 COQ2  
Affinity Capture-MS Homo sapiens
162 GFM1 85476
Proximity Label-MS Homo sapiens
163 HOXC8  
Affinity Capture-MS Homo sapiens
164 KRT18 3875
Co-fractionation Homo sapiens
165 C1QBP 708
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
166 QRSL1  
Proximity Label-MS Homo sapiens
167 DCAF4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
168 NSUN2 54888
Co-fractionation Homo sapiens
169 RAB2A 5862
Proximity Label-MS Homo sapiens
170 NUDT5 11164
Co-fractionation Homo sapiens
171 MRPS9 64965
Proximity Label-MS Homo sapiens
172 GATA1  
Affinity Capture-MS Homo sapiens
173 MRPS27 23107
Proximity Label-MS Homo sapiens
174 SLIRP 81892
Proximity Label-MS Homo sapiens
175 NDUFS1 4719
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
176 TPP1 1200
Co-fractionation Homo sapiens
177 MME 4311
Affinity Capture-MS Homo sapiens
178 GATA2  
Affinity Capture-MS Homo sapiens
179 PYCR1 5831
Proximity Label-MS Homo sapiens
180 GATB  
Proximity Label-MS Homo sapiens
181 C1orf94  
Affinity Capture-MS Homo sapiens
182 CARS2 79587
Proximity Label-MS Homo sapiens
183 LRPPRC 10128
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
184 CAPZB 832
Affinity Capture-MS Homo sapiens
185 HEATR3 55027
Affinity Capture-MS Homo sapiens
186 NDUFS3 4722
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
187 DCAF12L2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
188 HOXB8  
Affinity Capture-MS Homo sapiens
189 HINT2 84681
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
190 ITGA4 3676
Affinity Capture-MS Homo sapiens
191 NDUFV1 4723
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
192 MRPL4 51073
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
193 C19orf45  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
194 MDH2 4191
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
195 PLA2G2D  
Affinity Capture-MS Homo sapiens
196 ALAS1  
Proximity Label-MS Homo sapiens
197 MRPS25 64432
Proximity Label-MS Homo sapiens
198 MRPS33  
Proximity Label-MS Homo sapiens
199 P4HA1 5033
Co-fractionation Homo sapiens
200 THEM4  
Proximity Label-MS Homo sapiens
201 SAMM50 25813
Proximity Label-MS Homo sapiens
202 FASTKD5  
Proximity Label-MS Homo sapiens
203 HMGCS1 3157
Co-fractionation Homo sapiens
204 PARK2  
Affinity Capture-MS Homo sapiens
205 MKRN2 23609
Co-fractionation Homo sapiens
206 CHMP4B 128866
Affinity Capture-MS Homo sapiens
207 NTRK1 4914
Affinity Capture-MS Homo sapiens
208 GLI3 2737
Affinity Capture-MS Homo sapiens
209 LRRC8E 80131
Affinity Capture-MS Homo sapiens
210 FBXL6  
Affinity Capture-MS Homo sapiens
211 DCAF4L1  
Affinity Capture-MS Homo sapiens
212 UQCRH 7388
Co-fractionation Homo sapiens
213 LATS2 26524
Affinity Capture-MS Homo sapiens
214 ACAT1 38
Proximity Label-MS Homo sapiens
215 SLC25A12 8604
Proximity Label-MS Homo sapiens
216 AURKAIP1  
Affinity Capture-MS Homo sapiens
217 TRMT10C 54931
Proximity Label-MS Homo sapiens
218 PNPT1 87178
Proximity Label-MS Homo sapiens
219 MRPL10 124995
Affinity Capture-MS Homo sapiens
220 EEF2 1938
Co-fractionation Homo sapiens
221 MRPS14  
Proximity Label-MS Homo sapiens
222 CORO1C 23603
Co-fractionation Homo sapiens
223 OCIAD1 54940
Proximity Label-MS Homo sapiens
224 MRPS28  
Proximity Label-MS Homo sapiens
225 EMC2 9694
Co-fractionation Homo sapiens
226 HSDL2 84263
Proximity Label-MS Homo sapiens
227 CFL2 1073
Proximity Label-MS Homo sapiens
228 FOXRED1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
229 DNAJC3 5611
Co-fractionation Homo sapiens
230 MRPS36 92259
Proximity Label-MS Homo sapiens
231 SUCLG1 8802
Proximity Label-MS Homo sapiens
232 ARHGAP1 392
Co-fractionation Homo sapiens
233 IMMT 10989
Proximity Label-MS Homo sapiens
234 FGL1  
Affinity Capture-MS Homo sapiens
235 DEPDC1B 55789
Affinity Capture-MS Homo sapiens
236 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
237 PHB2 11331
Proximity Label-MS Homo sapiens
238 TSFM 10102
Proximity Label-MS Homo sapiens
239 PDK3 5165
Proximity Label-MS Homo sapiens
240 NDUFAF2  
Proximity Label-MS Homo sapiens
241 TUBG2  
Affinity Capture-MS Homo sapiens
242 ICT1 3396
Affinity Capture-MS Homo sapiens
243 PDHA1 5160
Proximity Label-MS Homo sapiens
244 LAMTOR2 28956
Co-fractionation Homo sapiens
245 MRPS10 55173
Proximity Label-MS Homo sapiens
246 C11orf52 91894
Proximity Label-MS Homo sapiens
247 MKI67  
Affinity Capture-MS Homo sapiens
248 CCT7 10574
Co-fractionation Homo sapiens
249 GUF1  
Proximity Label-MS Homo sapiens
250 NDUFS8 4728
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
251 MRPS18B 28973
Proximity Label-MS Homo sapiens
252 NDUFA2 4695
Proximity Label-MS Homo sapiens
253 AARS2  
Proximity Label-MS Homo sapiens
254 RPUSD3  
Affinity Capture-MS Homo sapiens
255 TAF1C  
Affinity Capture-MS Homo sapiens
256 FLNC 2318
Co-fractionation Homo sapiens
257 RPS27L 51065
Proximity Label-MS Homo sapiens
258 SERBP1 26135
Affinity Capture-MS Homo sapiens
259 MRPS22 56945
Proximity Label-MS Homo sapiens
260 DDX28  
Affinity Capture-MS Homo sapiens
261 TIMM44 10469
Proximity Label-MS Homo sapiens
262 UBE2H 7328
Affinity Capture-MS Homo sapiens
263 RIT1 6016
Negative Genetic Homo sapiens
264 PCED1A  
Affinity Capture-MS Homo sapiens
265 POR 5447
Co-fractionation Homo sapiens
266 CCT3 7203
Co-fractionation Homo sapiens
267 COIL  
Proximity Label-MS Homo sapiens
268 TRUB2  
Proximity Label-MS Homo sapiens
269 MRPL37 51253
Affinity Capture-MS Homo sapiens
270 ETFB 2109
Proximity Label-MS Homo sapiens
271 LYPLAL1 127018
Proximity Label-MS Homo sapiens
272 KRTAP13-2  
Affinity Capture-MS Homo sapiens
273 KIAA1429 25962
Affinity Capture-MS Homo sapiens
274 KIF20A 10112
Affinity Capture-MS Homo sapiens
275 MRPL20 55052
Proximity Label-MS Homo sapiens
276 CCDC69 26112
Affinity Capture-MS Homo sapiens
277 NDUFA7 4701
Proximity Label-MS Homo sapiens
278 MRPL23 6150
Affinity Capture-MS Homo sapiens
279 MRPS5 64969
Proximity Label-MS Homo sapiens
280 FBXW7  
Affinity Capture-MS Homo sapiens
281 MRPS24 64951
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
282 MRPL12 6182
Proximity Label-MS Homo sapiens
283 IFIT3 3437
Two-hybrid Homo sapiens
284 ATP2A2 488
Co-fractionation Homo sapiens
285 MKLN1  
Affinity Capture-MS Homo sapiens
286 MRPS26 64949
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
287 ATP5O 539
Proximity Label-MS Homo sapiens
288 EXD2  
Proximity Label-MS Homo sapiens
289 TATDN1 83940
Co-fractionation Homo sapiens
290 ATP5H 10476
Proximity Label-MS Homo sapiens
291 C6orf15  
Affinity Capture-MS Homo sapiens
292 USP2  
Affinity Capture-MS Homo sapiens
293 NDUFA6  
Proximity Label-MS Homo sapiens
294 DAP3 7818
Proximity Label-MS Homo sapiens
295 LAMTOR1 55004
Proximity Label-MS Homo sapiens
296 STOML2 30968
Proximity Label-MS Homo sapiens
297 E2F4  
Affinity Capture-MS Homo sapiens
298 PDK1 5163
Proximity Label-MS Homo sapiens
299 NDUFS4 4724
Proximity Label-MS Homo sapiens
300 PCK2 5106
Affinity Capture-MS Homo sapiens
301 EMD 2010
Proximity Label-MS Homo sapiens
302 MRPS34 65993
Proximity Label-MS Homo sapiens
303 ACOT2 10965
Proximity Label-MS Homo sapiens
304 A2M 2
Two-hybrid Homo sapiens
305 PTCD3 55037
Proximity Label-MS Homo sapiens
306 PFDN2 5202
Co-fractionation Homo sapiens
307 MMAB 326625
Proximity Label-MS Homo sapiens
308 GATA3  
Affinity Capture-MS Homo sapiens
309 C11orf1  
Affinity Capture-MS Homo sapiens
310 LYRM7  
Proximity Label-MS Homo sapiens
311 PML 5371
Affinity Capture-MS Homo sapiens
312 RPS15A 6210
Proximity Label-MS Homo sapiens
313 NIPSNAP1 8508
Proximity Label-MS Homo sapiens
314 ATP5B 506
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
315 DNAJB11 51726
Co-fractionation Homo sapiens
316 COX4I1 1327
Proximity Label-MS Homo sapiens
317 OXA1L  
Proximity Label-MS Homo sapiens
318 PDE12 201626
Affinity Capture-MS Homo sapiens
319 SFPQ 6421
Affinity Capture-MS Homo sapiens
320 MRPL21 219927
Proximity Label-MS Homo sapiens
321 MRRF  
Proximity Label-MS Homo sapiens
322 C9orf24  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
323 AMBRA1  
Affinity Capture-MS Homo sapiens
324 NDUFA9 4704
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
325 LETM1 3954
Proximity Label-MS Homo sapiens
326 ITLN2  
Affinity Capture-MS Homo sapiens
327 HMOX2 3163
Co-fractionation Homo sapiens
328 GCDH 2639
Proximity Label-MS Homo sapiens
329 NFS1 9054
Proximity Label-MS Homo sapiens
330 PRR27 401137
Affinity Capture-MS Homo sapiens
331 ARF6 382
Proximity Label-MS Homo sapiens
332 PYCR2 29920
Proximity Label-MS Homo sapiens
333 HDHD3 81932
Affinity Capture-MS Homo sapiens
334 ECHS1 1892
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
335 Espl1  
Affinity Capture-MS Mus musculus
336 MAPK6  
Affinity Capture-MS Homo sapiens
337 ODF3L1  
Affinity Capture-MS Homo sapiens
338 NIN 51199
Proximity Label-MS Homo sapiens
339 ATP6V1A 523
Co-fractionation Homo sapiens
340 ASPH 444
Co-fractionation Homo sapiens
341 KRAS 3845
Negative Genetic Homo sapiens
342 AK4 205
Proximity Label-MS Homo sapiens
343 ROCK1 6093
Co-fractionation Homo sapiens
344 MRPS2 51116
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
345 TUBG1 7283
Affinity Capture-MS Homo sapiens
346 TM9SF3 56889
Proximity Label-MS Homo sapiens
347 PNPLA8 50640
Proximity Label-MS Homo sapiens
348 ABHD10 55347
Affinity Capture-MS Homo sapiens
349 MRPS31  
Proximity Label-MS Homo sapiens
350 MRPL43 84545
Proximity Label-MS Homo sapiens
351 Ckap5 75786
Affinity Capture-MS Mus musculus
352 NDUFS7 374291
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
353 SUCLA2 8803
Proximity Label-MS Homo sapiens
354 C21orf33  
Proximity Label-MS Homo sapiens
355 SFXN1 94081
Proximity Label-MS Homo sapiens
356 C9orf173  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
357 SLC25A4 291
Proximity Label-MS Homo sapiens
358 GRSF1 2926
Proximity Label-MS Homo sapiens
359 NDUFAF4 29078
Proximity Label-MS Homo sapiens
360 METTL17  
Proximity Label-MS Homo sapiens
361 DCAF5  
Affinity Capture-MS Homo sapiens
362 ECSIT 51295
Two-hybrid Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here