Gene description for DDX6
Gene name DEAD (Asp-Glu-Ala-Asp) box helicase 6
Gene symbol DDX6
Other names/aliases HLR2
P54
RCK
Species Homo sapiens
 Database cross references - DDX6
ExoCarta ExoCarta_1656
Vesiclepedia VP_1656
Entrez Gene 1656
HGNC 2747
MIM 600326
UniProt P26196  
 DDX6 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Endothelial cells 26027894    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for DDX6
Molecular Function
    DNA clamp loader activity GO:0003689 IEA
    RNA binding GO:0003723 HDA
    RNA helicase activity GO:0003724 IEA
    mRNA binding GO:0003729 IBA
    helicase activity GO:0004386 TAS
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    ATP hydrolysis activity GO:0016887 IEA
    protein domain specific binding GO:0019904 IPI
    cadherin binding GO:0045296 HDA
    cohesin loader activity GO:0061775 IEA
    chromatin extrusion motor activity GO:0140584 IEA
    ATP-dependent H3-H4 histone complex chaperone activity GO:0140665 IEA
    ATP-dependent H2AZ histone chaperone activity GO:0140849 IEA
Biological Process
    chromatin remodeling GO:0006338 IEA
    negative regulation of translation GO:0017148 IBA
    negative regulation of translation GO:0017148 IDA
    viral RNA genome packaging GO:0019074 IMP
    stem cell population maintenance GO:0019827 IEA
    neuron differentiation GO:0030182 IEA
    P-body assembly GO:0033962 IBA
    P-body assembly GO:0033962 IDA
    P-body assembly GO:0033962 IDA
    P-body assembly GO:0033962 IMP
    stress granule assembly GO:0034063 IBA
    miRNA-mediated gene silencing by inhibition of translation GO:0035278 IDA
    negative regulation of neuron differentiation GO:0045665 IEA
    chromatin looping GO:0140588 IEA
Subcellular Localization
    P-body GO:0000932 IBA
    P-body GO:0000932 IDA
    P-body GO:0000932 IMP
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 IDA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    cytoplasmic stress granule GO:0010494 IBA
    cytoplasmic stress granule GO:0010494 IDA
    membrane GO:0016020 HDA
    RISC complex GO:0016442 IDA
    cytoplasmic ribonucleoprotein granule GO:0036464 IDA
 Experiment description of studies that identified DDX6 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
15
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
20
Experiment ID 226
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD9|FLOT1
Enriched markers
✔
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
✘ Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
21
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
25
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
28
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
31
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
33
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
34
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
37
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
38
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
39
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
40
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
41
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
42
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
43
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for DDX6
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EIF3A 8661
Affinity Capture-MS Homo sapiens
2 HDAC4  
Affinity Capture-MS Homo sapiens
3 NUF2  
Affinity Capture-MS Homo sapiens
4 ZNF24  
Two-hybrid Homo sapiens
5 USH1G  
Two-hybrid Homo sapiens
6 UBE2A  
Affinity Capture-MS Homo sapiens
7 SRPK2 6733
Biochemical Activity Homo sapiens
8 AES 166
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
9 CRK 1398
Affinity Capture-MS Homo sapiens
10 CAP1 10487
Co-fractionation Homo sapiens
11 EIF1 10209
Affinity Capture-MS Homo sapiens
12 PRPF40A 55660
Affinity Capture-MS Homo sapiens
13 NARFL 64428
Co-fractionation Homo sapiens
14 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
15 METAP2 10988
Affinity Capture-MS Homo sapiens
16 ETFA 2108
Co-fractionation Homo sapiens
17 EIF3E 3646
Affinity Capture-MS Homo sapiens
18 ZBTB14  
Two-hybrid Homo sapiens
19 MECP2 4204
Affinity Capture-MS Homo sapiens
20 RPS11 6205
Affinity Capture-MS Homo sapiens
21 LSM1 27257
Affinity Capture-MS Homo sapiens
22 RBM14 10432
Two-hybrid Homo sapiens
23 KIF14 9928
Affinity Capture-MS Homo sapiens
24 EMC9  
Affinity Capture-MS Homo sapiens
25 AGO2 27161
Co-fractionation Homo sapiens
26 HEXIM1 10614
Affinity Capture-MS Homo sapiens
27 MEPCE 56257
Affinity Capture-MS Homo sapiens
28 SHMT1 6470
Two-hybrid Homo sapiens
29 TUFM 7284
Co-fractionation Homo sapiens
30 PNMA5 114824
Two-hybrid Homo sapiens
31 MAGT1 84061
Affinity Capture-MS Homo sapiens
32 UBASH3B 84959
Affinity Capture-MS Homo sapiens
33 PABPC1 26986
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 CDH1 999
Proximity Label-MS Homo sapiens
35 YAP1 10413
Affinity Capture-MS Homo sapiens
36 OGT 8473
Co-fractionation Homo sapiens
37 RPL31 6160
Affinity Capture-MS Homo sapiens
38 SYNCRIP 10492
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
39 ASCC2 84164
Affinity Capture-MS Homo sapiens
40 YWHAQ 10971
Affinity Capture-MS Homo sapiens
41 RUNDC3A  
Two-hybrid Homo sapiens
42 HECTD1 25831
Affinity Capture-MS Homo sapiens
43 PAK7  
Two-hybrid Homo sapiens
44 ZBTB43  
Two-hybrid Homo sapiens
45 SP100 6672
Affinity Capture-MS Homo sapiens
46 EIF3G 8666
Affinity Capture-MS Homo sapiens
47 PITRM1 10531
Co-fractionation Homo sapiens
48 CUL3 8452
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
49 YWHAZ 7534
Affinity Capture-MS Homo sapiens
50 SH3RF2  
Affinity Capture-MS Homo sapiens
51 EIF4E 1977
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
52 EIF2S2 8894
Affinity Capture-MS Homo sapiens
53 CNKSR3 154043
Two-hybrid Homo sapiens
54 FN1 2335
Affinity Capture-MS Homo sapiens
55 ZNF823  
Affinity Capture-MS Homo sapiens
56 EIF3CL 728689
Affinity Capture-MS Homo sapiens
57 PCBP1 5093
Affinity Capture-MS Homo sapiens
58 STAT1 6772
Reconstituted Complex Homo sapiens
59 STXBP2 6813
Co-fractionation Homo sapiens
60 RPA3 6119
Proximity Label-MS Homo sapiens
61 TIMM8B 26521
Co-fractionation Homo sapiens
62 NDC80 10403
Affinity Capture-MS Homo sapiens
63 SORBS3 10174
Two-hybrid Homo sapiens
64 GNL3 26354
Affinity Capture-MS Homo sapiens
65 RPS16 6217
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 YBX1 4904
Affinity Capture-MS Homo sapiens
67 TP53BP2  
Two-hybrid Homo sapiens
68 LRRC6  
Two-hybrid Homo sapiens
69 PLEC 5339
Co-fractionation Homo sapiens
70 RBM25 58517
Affinity Capture-MS Homo sapiens
71 EIF3I 8668
Affinity Capture-MS Homo sapiens
72 WWOX 51741
Affinity Capture-MS Homo sapiens
73 GIGYF1  
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
74 LRPPRC 10128
Co-fractionation Homo sapiens
75 LSM14A 26065
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
76 EIF4G3 8672
Affinity Capture-MS Homo sapiens
77 G3BP2 9908
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
78 IK 3550
Two-hybrid Homo sapiens
79 TCF4  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
80 RPS24 6229
Affinity Capture-MS Homo sapiens
81 PSMA5 5686
Affinity Capture-MS Homo sapiens
82 CLTA 1211
Affinity Capture-MS Homo sapiens
83 LIMD1 8994
Co-fractionation Homo sapiens
84 RPL23A 6147
Affinity Capture-MS Homo sapiens
85 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
86 ORC2  
Affinity Capture-MS Homo sapiens
87 FAM98A 25940
Affinity Capture-MS Homo sapiens
88 EIF3K 27335
Affinity Capture-MS Homo sapiens
89 ARL6IP5 10550
Affinity Capture-MS Homo sapiens
90 TARDBP 23435
Affinity Capture-MS Homo sapiens
91 BTF3 689
Affinity Capture-MS Homo sapiens
92 ZFR 51663
Affinity Capture-MS Homo sapiens
93 EIF4A1 1973
Affinity Capture-MS Homo sapiens
94 CAND1 55832
Affinity Capture-MS Homo sapiens
95 ARHGEF16 27237
Co-fractionation Homo sapiens
96 RPS3 6188
Affinity Capture-MS Homo sapiens
97 RPS18 6222
Affinity Capture-MS Homo sapiens
98 RPL32 6161
Affinity Capture-MS Homo sapiens
99 JAKMIP1 152789
Two-hybrid Homo sapiens
100 DPYSL2 1808
Co-fractionation Homo sapiens
101 TCF12  
Two-hybrid Homo sapiens
102 H1FX 8971
Affinity Capture-MS Homo sapiens
103 CCDC14  
Two-hybrid Homo sapiens
104 MAGOHB 55110
Affinity Capture-MS Homo sapiens
105 OBSL1 23363
Affinity Capture-MS Homo sapiens
106 YWHAH 7533
Affinity Capture-MS Homo sapiens
107 VCAM1 7412
Affinity Capture-MS Homo sapiens
108 TRIM25 7706
Co-fractionation Homo sapiens
109 CALCOCO2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
110 YWHAB 7529
Affinity Capture-MS Homo sapiens
111 GTF2I 2969
Co-fractionation Homo sapiens
112 HNRNPA0 10949
Affinity Capture-MS Homo sapiens
113 DDX21 9188
Affinity Capture-MS Homo sapiens
114 RPL4 6124
Affinity Capture-MS Homo sapiens
115 KLC4 89953
Two-hybrid Homo sapiens
116 RPL35 11224
Affinity Capture-MS Homo sapiens
117 SIPA1L2  
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
118 BEND7 222389
Two-hybrid Homo sapiens
119 PATL1 219988
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
120 BCL6  
Affinity Capture-MS Homo sapiens
121 Rrbp1  
Affinity Capture-MS Mus musculus
122 RPLP0 6175
Affinity Capture-MS Homo sapiens
123 FAM76B  
Affinity Capture-MS Homo sapiens
124 USP4 7375
Affinity Capture-MS Homo sapiens
125 RPS2 6187
Affinity Capture-MS Homo sapiens
126 PAN3 255967
Affinity Capture-MS Homo sapiens
127 XPO1 7514
Affinity Capture-MS Homo sapiens
128 SAP30L  
Affinity Capture-MS Homo sapiens
129 KRTAP10-8  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
130 TXNRD1 7296
Co-fractionation Homo sapiens
131 EGFR 1956
Negative Genetic Homo sapiens
132 IKZF1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
133 FAM195A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
134 LARS 51520
Co-fractionation Homo sapiens
135 RPS27 6232
Affinity Capture-MS Homo sapiens
136 MYC  
Affinity Capture-MS Homo sapiens
137 HNRNPAB 3182
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
138 CUL7 9820
Affinity Capture-MS Homo sapiens
139 DDRGK1 65992
Affinity Capture-MS Homo sapiens
140 HUWE1 10075
Affinity Capture-MS Homo sapiens
141 EIF3H 8667
Affinity Capture-MS Homo sapiens
142 DSP 1832
Co-fractionation Homo sapiens
143 RPL19 6143
Affinity Capture-MS Homo sapiens
144 RPL13 6137
Affinity Capture-MS Homo sapiens
145 SPOP  
Affinity Capture-MS Homo sapiens
146 PRRC2A 7916
Affinity Capture-MS Homo sapiens
147 TRAF2 7186
Two-hybrid Homo sapiens
148 PARP1 142
Proximity Label-MS Homo sapiens
149 ILF3 3609
Affinity Capture-MS Homo sapiens
150 BHLHB9 80823
Two-hybrid Homo sapiens
151 ZBTB8A  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
152 FXR1 8087
Two-hybrid Homo sapiens
153 THOP1 7064
Co-fractionation Homo sapiens
154 RPS12 6206
Affinity Capture-MS Homo sapiens
155 RPS4X 6191
Affinity Capture-MS Homo sapiens
156 RPS5 6193
Affinity Capture-MS Homo sapiens
157 RPS26 6231
Affinity Capture-MS Homo sapiens
158 EIF3M 10480
Affinity Capture-MS Homo sapiens
159 RPSA 3921
Affinity Capture-MS Homo sapiens
160 NAB2 4665
Two-hybrid Homo sapiens
161 RPL7A 6130
Affinity Capture-MS Homo sapiens
162 C1QBP 708
Affinity Capture-MS Homo sapiens
163 PRMT1 3276
Affinity Capture-MS Homo sapiens
164 TIMM13 26517
Co-fractionation Homo sapiens
165 ATP13A1 57130
Affinity Capture-MS Homo sapiens
166 CNOT7 29883
Co-fractionation Homo sapiens
167 RPL26L1 51121
Affinity Capture-MS Homo sapiens
168 SCYL1 57410
Two-hybrid Homo sapiens
169 BEGAIN  
Two-hybrid Homo sapiens
170 YWHAE 7531
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
171 REL 5966
Two-hybrid Homo sapiens
172 FCHO1  
Two-hybrid Homo sapiens
173 RPS19 6223
Affinity Capture-MS Homo sapiens
174 SSB 6741
Affinity Capture-MS Homo sapiens
175 HNRNPR 10236
Affinity Capture-MS Homo sapiens
176 PPP1R10  
Affinity Capture-MS Homo sapiens
177 RPS6KB2  
Affinity Capture-MS Homo sapiens
178 TRIM54  
Two-hybrid Homo sapiens
179 ATG13 9776
Affinity Capture-MS Homo sapiens
180 CAPZB 832
Affinity Capture-MS Homo sapiens
181 RPL10A 4736
Affinity Capture-MS Homo sapiens
182 SRP19 6728
Affinity Capture-MS Homo sapiens
183 PAK4 10298
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
184 MCM2 4171
Affinity Capture-MS Homo sapiens
185 EIF3B 8662
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
186 KRT40  
Two-hybrid Homo sapiens
187 POLR1E  
Affinity Capture-MS Homo sapiens
188 SSR1 6745
Affinity Capture-MS Homo sapiens
189 NXT1  
Affinity Capture-MS Homo sapiens
190 RPL29 6159
Affinity Capture-MS Homo sapiens
191 YAF2  
Affinity Capture-MS Homo sapiens
192 PABPC4 8761
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
193 RBM8A 9939
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
194 RPL27 6155
Affinity Capture-MS Homo sapiens
195 KRT34  
Two-hybrid Homo sapiens
196 PRPH 5630
Two-hybrid Homo sapiens
197 LSM14B 149986
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
198 PARK2  
Affinity Capture-MS Homo sapiens
199 PNRC1 10957
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
200 PAN2  
Affinity Capture-MS Homo sapiens
201 PPIL4  
Affinity Capture-MS Homo sapiens
202 GOLGA2 2801
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
203 EPS8L2 64787
Co-fractionation Homo sapiens
204 ACACA 31
Positive Genetic Homo sapiens
205 RPL5 6125
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
206 POU6F2  
Two-hybrid Homo sapiens
207 RCCD1  
Affinity Capture-MS Homo sapiens
208 SLAIN1 122060
Two-hybrid Homo sapiens
209 CNOT1 23019
Co-crystal Structure Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
210 NTRK1 4914
Affinity Capture-MS Homo sapiens
211 DCP1A 55802
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
212 RPL36 25873
Affinity Capture-MS Homo sapiens
213 ACTB 60
Co-fractionation Homo sapiens
214 AAMDC  
Affinity Capture-MS Homo sapiens
215 DHX9 1660
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
216 HNRNPA3 220988
Affinity Capture-MS Homo sapiens
217 EIF4A2 1974
Affinity Capture-MS Homo sapiens
218 LARP1 23367
Affinity Capture-MS Homo sapiens
219 ARHGAP17 55114
Co-fractionation Homo sapiens
220 HNRNPDL 9987
Affinity Capture-MS Homo sapiens
221 DISC1 27185
Two-hybrid Homo sapiens
222 SPATA6  
Two-hybrid Homo sapiens
223 SIRPA 140885
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
224 DCAF13 25879
Affinity Capture-MS Homo sapiens
225 RPL21 6144
Affinity Capture-MS Homo sapiens
226 YY1 7528
Affinity Capture-MS Homo sapiens
227 FBXO6 26270
Affinity Capture-MS Homo sapiens
228 KRTAP10-3  
Two-hybrid Homo sapiens
229 FAM195B 348262
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
230 AP2M1 1173
Affinity Capture-MS Homo sapiens
231 NCAPH 23397
Affinity Capture-MS Homo sapiens
232 NSRP1  
Affinity Capture-MS Homo sapiens
233 PSPC1 55269
Affinity Capture-MS Homo sapiens
234 PPWD1 23398
Co-fractionation Homo sapiens
235 FDPS 2224
Co-fractionation Homo sapiens
236 RPS14 6208
Affinity Capture-MS Homo sapiens
237 RPL22 6146
Affinity Capture-MS Homo sapiens
238 RPLP1 6176
Affinity Capture-MS Homo sapiens
239 RPL18 6141
Affinity Capture-MS Homo sapiens
240 KTN1 3895
Affinity Capture-MS Homo sapiens
241 HSPA9 3313
Co-fractionation Homo sapiens
242 AKAP1 8165
Affinity Capture-MS Homo sapiens
243 RBMS2 5939
Co-fractionation Homo sapiens
244 CBX4  
Affinity Capture-MS Homo sapiens
245 SUGT1 10910
Co-fractionation Homo sapiens
246 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
247 RPS25 6230
Affinity Capture-MS Homo sapiens
248 JUP 3728
Two-hybrid Homo sapiens
249 FBXL6  
Affinity Capture-MS Homo sapiens
250 RPL6 6128
Affinity Capture-MS Homo sapiens
251 RPS21 6227
Affinity Capture-MS Homo sapiens
252 PRRC2C 23215
Affinity Capture-MS Homo sapiens
253 ALDH1B1 219
Co-fractionation Homo sapiens
254 SEPHS2  
Co-fractionation Homo sapiens
255 PLOD1 5351
Co-fractionation Homo sapiens
256 EDC3 80153
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
257 RPL34 6164
Affinity Capture-MS Homo sapiens
258 UFL1 23376
Affinity Capture-MS Homo sapiens
259 TRIM37  
Two-hybrid Homo sapiens
260 SNIP1  
Affinity Capture-MS Homo sapiens
261 RPL38 6169
Affinity Capture-MS Homo sapiens
262 RPS7 6201
Affinity Capture-MS Homo sapiens
263 RPL8 6132
Affinity Capture-MS Homo sapiens
264 RPS27L 51065
Affinity Capture-MS Homo sapiens
265 SERBP1 26135
Affinity Capture-MS Homo sapiens
266 BIRC7  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
267 RC3H1 149041
Co-fractionation Homo sapiens
268 ATXN3 4287
Affinity Capture-MS Homo sapiens
269 EP300 2033
Affinity Capture-MS Homo sapiens
270 CASC3  
Affinity Capture-MS Homo sapiens
271 PBDC1 51260
Co-fractionation Homo sapiens
272 EIF3L 51386
Affinity Capture-MS Homo sapiens
273 UBE2H 7328
Affinity Capture-MS Homo sapiens
274 ADRBK1 156
Co-fractionation Homo sapiens
275 SLFN11 91607
Affinity Capture-MS Homo sapiens
276 IGF2BP1 10642
Affinity Capture-MS Homo sapiens
277 Edc4  
Affinity Capture-MS Mus musculus
278 RPS3A 6189
Affinity Capture-MS Homo sapiens
279 VAPA 9218
Affinity Capture-MS Homo sapiens
280 DCP1B  
Affinity Capture-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
281 RPL30 6156
Affinity Capture-MS Homo sapiens
282 PPIE 10450
Affinity Capture-MS Homo sapiens
283 RPL13A 23521
Affinity Capture-MS Homo sapiens
284 RPL37A 6168
Affinity Capture-MS Homo sapiens
285 TSG101 7251
Affinity Capture-MS Homo sapiens
286 RPL10 6134
Affinity Capture-MS Homo sapiens
287 PPIA 5478
Co-fractionation Homo sapiens
288 AFF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
289 ILF2 3608
Affinity Capture-MS Homo sapiens
290 EIF4ENIF1 56478
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
291 RPS20 6224
Affinity Capture-MS Homo sapiens
292 CEP70  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
293 ATXN2L 11273
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
294 FAM212A  
Two-hybrid Homo sapiens
295 COPS5 10987
Affinity Capture-MS Homo sapiens
296 RPL24 6152
Affinity Capture-MS Homo sapiens
297 WDR12 55759
Co-fractionation Homo sapiens
298 YWHAG 7532
Affinity Capture-MS Homo sapiens
299 MTUS2 23281
Two-hybrid Homo sapiens
300 EED  
Affinity Capture-MS Homo sapiens
301 SRP68 6730
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
302 MYCN  
Affinity Capture-MS Homo sapiens
303 CSNK1D 1453
Affinity Capture-MS Homo sapiens
304 COMMD4 54939
Co-fractionation Homo sapiens
305 DVL2 1856
Affinity Capture-MS Homo sapiens
306 LSM12 124801
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
307 E2F4  
Affinity Capture-MS Homo sapiens
308 RPS23 6228
Affinity Capture-MS Homo sapiens
309 SRP9 6726
Affinity Capture-MS Homo sapiens
310 RB1CC1 9821
Affinity Capture-MS Homo sapiens
311 RPL39 6170
Affinity Capture-MS Homo sapiens
312 Lsm14a  
Affinity Capture-MS Mus musculus
313 SDCCAG3  
Two-hybrid Homo sapiens
314 NONO 4841
Two-hybrid Homo sapiens
315 STAU1 6780
Affinity Capture-MS Homo sapiens
316 PRDM16 63976
Two-hybrid Homo sapiens
317 CRKL 1399
Affinity Capture-MS Homo sapiens
318 PNLIPRP2  
Affinity Capture-MS Homo sapiens
319 DICER1  
Co-fractionation Homo sapiens
320 RPL27A 6157
Affinity Capture-MS Homo sapiens
321 ELAVL1 1994
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
322 CEP76  
Two-hybrid Homo sapiens
323 RPS15A 6210
Affinity Capture-MS Homo sapiens
324 CEBPA  
Protein-peptide Homo sapiens
325 MESDC2 23184
Two-hybrid Homo sapiens
326 MAT2A 4144
Co-fractionation Homo sapiens
327 TRMT1 55621
Co-fractionation Homo sapiens
328 ASCC3 10973
Affinity Capture-MS Homo sapiens
329 PRPF4B 8899
Affinity Capture-MS Homo sapiens
330 RPLP2 6181
Affinity Capture-MS Homo sapiens
331 TRIM31  
Affinity Capture-MS Homo sapiens
332 OTUD1 220213
Affinity Capture-MS Homo sapiens
333 DES 1674
Two-hybrid Homo sapiens
334 EIF4G1 1981
Affinity Capture-MS Homo sapiens
335 TSPYL5  
Affinity Capture-MS Homo sapiens
336 HCFC1 3054
Co-fractionation Homo sapiens
337 RPS8 6202
Affinity Capture-MS Homo sapiens
338 CTTN 2017
Affinity Capture-MS Homo sapiens
339 RPL3 6122
Affinity Capture-MS Homo sapiens
340 LRRC16A 55604
Co-fractionation Homo sapiens
341 FKBP5 2289
Co-fractionation Homo sapiens
342 AGO4  
Affinity Capture-MS Homo sapiens
343 DDX42 11325
Affinity Capture-MS Homo sapiens
344 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
345 TRIM27  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
346 RPL11 6135
Affinity Capture-MS Homo sapiens
347 ZC2HC1C  
Two-hybrid Homo sapiens
348 C9orf72  
Affinity Capture-MS Homo sapiens
349 AP1S1 1174
Co-fractionation Homo sapiens
350 BAG4  
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
351 RBM11  
Two-hybrid Homo sapiens
352 EIF3D 8664
Affinity Capture-MS Homo sapiens
353 FAM120A 23196
Affinity Capture-MS Homo sapiens
354 PDLIM7 9260
Two-hybrid Homo sapiens
355 SIRT6  
Affinity Capture-MS Homo sapiens
356 RRBP1 6238
Co-fractionation Homo sapiens
357 EFHC2  
Two-hybrid Homo sapiens
358 SRP72 6731
Affinity Capture-MS Homo sapiens
359 VPS52 6293
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
360 INPPL1 3636
Affinity Capture-MS Homo sapiens
361 MNDA 4332
Affinity Capture-MS Homo sapiens
362 NUFIP2 57532
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
363 GNB2L1 10399
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
364 ATXN2 6311
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
365 PIM1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
366 ARHGAP18 93663
Affinity Capture-MS Homo sapiens
367 ZBTB10 65986
Two-hybrid Homo sapiens
368 TAF2  
Affinity Capture-MS Homo sapiens
369 IDE 3416
Co-fractionation Homo sapiens
370 RPS28 6234
Affinity Capture-MS Homo sapiens
371 EDC4 23644
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
372 MAGED1 9500
Two-hybrid Homo sapiens
373 TRIP4 9325
Affinity Capture-MS Homo sapiens
374 PYGB 5834
Co-fractionation Homo sapiens
375 UPF1 5976
Affinity Capture-MS Homo sapiens
376 PINK1  
Affinity Capture-MS Homo sapiens
377 RPS6 6194
Affinity Capture-MS Homo sapiens
378 HNRNPU 3192
Affinity Capture-MS Homo sapiens
379 CCDC136  
Two-hybrid Homo sapiens
380 METTL17  
Affinity Capture-MS Homo sapiens
381 RPL17 6139
Affinity Capture-MS Homo sapiens
382 CDC5L 988
Affinity Capture-MS Homo sapiens
383 CNDP2 55748
Co-fractionation Homo sapiens
384 RPS13 6207
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which DDX6 is involved
PathwayEvidenceSource
Deadenylation-dependent mRNA decay TAS Reactome
Metabolism of RNA TAS Reactome
mRNA decay by 5' to 3' exoribonuclease TAS Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here