Gene description for COX4I1
Gene name cytochrome c oxidase subunit IV isoform 1
Gene symbol COX4I1
Other names/aliases COX4
COX4-1
COXIV
Species Homo sapiens
 Database cross references - COX4I1
ExoCarta ExoCarta_1327
Vesiclepedia VP_1327
Entrez Gene 1327
HGNC 2265
MIM 123864
UniProt P13073  
 COX4I1 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Colorectal cancer cells 17956143    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
T lymphocytes 34108659    
 Gene ontology annotations for COX4I1
Molecular Function
    cytochrome-c oxidase activity GO:0004129 TAS
    protein binding GO:0005515 IPI
Biological Process
    generation of precursor metabolites and energy GO:0006091 TAS
    mitochondrial electron transport, cytochrome c to oxygen GO:0006123 IBA
    mitochondrial electron transport, cytochrome c to oxygen GO:0006123 NAS
    cellular respiration GO:0045333 NAS
    proton transmembrane transport GO:1902600 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    mitochondrion GO:0005739 HDA
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IDA
    mitochondrial inner membrane GO:0005743 ISS
    mitochondrial inner membrane GO:0005743 TAS
    mitochondrial intermembrane space GO:0005758 TAS
    cytosol GO:0005829 IEA
    membrane GO:0016020 HDA
    mitochondrial membrane GO:0031966 IDA
    respiratory chain complex IV GO:0045277 IBA
    respiratory chain complex IV GO:0045277 IMP
 Experiment description of studies that identified COX4I1 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
10
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 234
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
17
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
18
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
19
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
20
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
28
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
33
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
34
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for COX4I1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SLC25A13 10165
Proximity Label-MS Homo sapiens
2 UQCRFS1 7386
Proximity Label-MS Homo sapiens
3 DNAJC11 55735
Proximity Label-MS Homo sapiens
4 TPM2 7169
Co-fractionation Homo sapiens
5 CCDC90B  
Proximity Label-MS Homo sapiens
6 MCU 90550
Proximity Label-MS Homo sapiens
7 TIMM8A 1678
Proximity Label-MS Homo sapiens
8 PMPCA 23203
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
9 COX7A2L 9167
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 ETFA 2108
Proximity Label-MS Homo sapiens
11 FXN  
Co-fractionation Homo sapiens
12 POLRMT 5442
Proximity Label-MS Homo sapiens
13 MTX2 10651
Proximity Label-MS Homo sapiens
14 TBCA 6902
Co-fractionation Homo sapiens
15 BET1 10282
Affinity Capture-MS Homo sapiens
16 SLC30A9 10463
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 PREPL 9581
Proximity Label-MS Homo sapiens
18 VWA8 23078
Proximity Label-MS Homo sapiens
19 KIF14 9928
Affinity Capture-MS Homo sapiens
20 EMC1 23065
Proximity Label-MS Homo sapiens
21 KLF16  
Affinity Capture-MS Homo sapiens
22 PPM1B 5495
Affinity Capture-MS Homo sapiens
23 MTCH2 23788
Co-fractionation Homo sapiens
24 MTMR11  
Affinity Capture-MS Homo sapiens
25 PGAM5 192111
Proximity Label-MS Homo sapiens
26 MICU2 221154
Proximity Label-MS Homo sapiens
27 TUFM 7284
Proximity Label-MS Homo sapiens
28 UBAC2 337867
Proximity Label-MS Homo sapiens
29 TTC19  
Proximity Label-MS Homo sapiens
30 CYBA 1535
Co-fractionation Homo sapiens
31 SPR 6697
Co-fractionation Homo sapiens
32 CCDC109B 55013
Proximity Label-MS Homo sapiens
33 CYC1 1537
Co-fractionation Homo sapiens
34 PIGS 94005
Affinity Capture-MS Homo sapiens
35 DBT 1629
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 MTRF1L  
Proximity Label-MS Homo sapiens
37 MICU1 10367
Proximity Label-MS Homo sapiens
38 VDAC2 7417
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
39 TRIM63  
Two-hybrid Homo sapiens
40 MRPL41 64975
Proximity Label-MS Homo sapiens
41 SSR4 6748
Co-fractionation Homo sapiens
42 DST 667
Cross-Linking-MS (XL-MS) Homo sapiens
43 CISD1 55847
Co-fractionation Homo sapiens
44 HSPA5 3309
Co-fractionation Homo sapiens
45 EARS2  
Proximity Label-MS Homo sapiens
46 HADHB 3032
Co-fractionation Homo sapiens
47 HADHA 3030
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
48 MTIF2 4528
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
49 CDCA3 83461
Proximity Label-MS Homo sapiens
50 GOLT1B 51026
Affinity Capture-MS Homo sapiens
51 BCAP31 10134
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
52 CUL3 8452
Affinity Capture-MS Homo sapiens
53 GPD2 2820
Proximity Label-MS Homo sapiens
54 VARS2  
Proximity Label-MS Homo sapiens
55 ZNF782  
Co-fractionation Homo sapiens
56 SOAT1 6646
Affinity Capture-MS Homo sapiens
57 RPA3 6119
Proximity Label-MS Homo sapiens
58 COX6C 1345
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 DLST 1743
Proximity Label-MS Homo sapiens
60 NCLN 56926
Proximity Label-MS Homo sapiens
61 AUH 549
Proximity Label-MS Homo sapiens
62 DUSP21  
Affinity Capture-MS Homo sapiens
63 NDUFA10 4705
Co-fractionation Homo sapiens
64 PARL  
Proximity Label-MS Homo sapiens
65 COX2 4513
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 PLGRKT 55848
Proximity Label-MS Homo sapiens
67 DLAT 1737
Proximity Label-MS Homo sapiens
68 TPM4 7171
Co-fractionation Homo sapiens
69 SCCPDH 51097
Co-fractionation Homo sapiens
70 GBAS 2631
Co-fractionation Homo sapiens
71 COX7A1  
Affinity Capture-MS Homo sapiens
72 DUSP19  
Affinity Capture-MS Homo sapiens
73 DNAJC28  
Proximity Label-MS Homo sapiens
74 GLS 2744
Proximity Label-MS Homo sapiens
75 CCDC58 131076
Proximity Label-MS Homo sapiens
76 CLPX 10845
Proximity Label-MS Homo sapiens
77 MTPN 136319
Co-fractionation Homo sapiens
78 TIMM13 26517
Proximity Label-MS Homo sapiens
79 SUCLG2 8801
Proximity Label-MS Homo sapiens
80 LARS2 23395
Proximity Label-MS Homo sapiens
81 C7orf55  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
82 COX5A 9377
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
83 SSBP1 6742
Proximity Label-MS Homo sapiens
84 ATAD3A 55210
Proximity Label-MS Homo sapiens
85 NDUFAF3 25915
Proximity Label-MS Homo sapiens
86 ISCA2 122961
Co-fractionation Homo sapiens
87 ACOT1 641371
Proximity Label-MS Homo sapiens
88 SLC25A51  
Proximity Label-MS Homo sapiens
89 CISD2 493856
Co-fractionation Homo sapiens
90 TMBIM4  
Affinity Capture-MS Homo sapiens
91 SMIM20  
Proximity Label-MS Homo sapiens
92 POLG  
Proximity Label-MS Homo sapiens
93 SP7  
Proximity Label-MS Homo sapiens
94 GSTP1 2950
Co-fractionation Homo sapiens
95 AFG3L2 10939
Proximity Label-MS Homo sapiens
96 IARS2 55699
Proximity Label-MS Homo sapiens
97 ALDH2 217
Proximity Label-MS Homo sapiens
98 NDUFA4 4697
Co-fractionation Homo sapiens
99 FFAR1  
Affinity Capture-MS Homo sapiens
100 NDUFS2 4720
Proximity Label-MS Homo sapiens
101 HCCS 3052
Proximity Label-MS Homo sapiens
102 TIMM17B  
Proximity Label-MS Homo sapiens
103 PRC1 9055
Affinity Capture-MS Homo sapiens
104 NDUFA5 4698
Proximity Label-MS Homo sapiens
105 VAPB 9217
Co-fractionation Homo sapiens
106 LACTB 114294
Proximity Label-MS Homo sapiens
107 PHB 5245
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
108 TOMM40 10452
Co-fractionation Homo sapiens
109 NDUFV3 4731
Proximity Label-MS Homo sapiens
110 PMPCB 9512
Proximity Label-MS Homo sapiens
111 TACO1  
Proximity Label-MS Homo sapiens
112 SDCBP 6386
Two-hybrid Homo sapiens
113 PDPR 55066
Proximity Label-MS Homo sapiens
114 NDUFB1 4707
Co-fractionation Homo sapiens
115 PPM1E  
Affinity Capture-MS Homo sapiens
116 C6orf203  
Proximity Label-MS Homo sapiens
117 AASS  
Proximity Label-MS Homo sapiens
118 NDUFA8 4702
Proximity Label-MS Homo sapiens
119 NELFCD 51497
Affinity Capture-MS Homo sapiens
120 PMAIP1  
Affinity Capture-MS Homo sapiens
121 NDUFA2 4695
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
122 UQCRC1 7384
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
123 ATP6V1E1 529
Co-fractionation Homo sapiens
124 GTPBP3  
Proximity Label-MS Homo sapiens
125 ZCCHC8 55596
Proximity Label-MS Homo sapiens
126 MRPL44  
Proximity Label-MS Homo sapiens
127 IBA57  
Proximity Label-MS Homo sapiens
128 AIFM1 9131
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
129 CANX 821
Co-fractionation Homo sapiens
130 MRPS35 60488
Proximity Label-MS Homo sapiens
131 MTIF3  
Proximity Label-MS Homo sapiens
132 H2AFX 3014
Proximity Label-MS Homo sapiens
133 RMND1 55005
Proximity Label-MS Homo sapiens
134 HSD17B10 3028
Proximity Label-MS Homo sapiens
135 DUSP6 1848
Affinity Capture-MS Homo sapiens
136 TOMM70A 9868
Proximity Label-MS Homo sapiens
137 SMDT1  
Co-fractionation Homo sapiens
138 TPM1 7168
Co-fractionation Homo sapiens
139 CNR2  
Affinity Capture-MS Homo sapiens
140 ACAD9 28976
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
141 NDUFV2 4729
Proximity Label-MS Homo sapiens
142 MCUR1 63933
Proximity Label-MS Homo sapiens
143 PPIF 10105
Proximity Label-MS Homo sapiens
144 PIGP  
Affinity Capture-MS Homo sapiens
145 CS 1431
Proximity Label-MS Homo sapiens
146 C17orf80 55028
Proximity Label-MS Homo sapiens
147 PRKCSH 5589
Proximity Label-MS Homo sapiens
148 ALDH4A1 8659
Co-fractionation Homo sapiens
149 BCKDHA 593
Co-fractionation Homo sapiens
150 COX8A  
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
151 SHMT2 6472
Proximity Label-MS Homo sapiens
152 MMGT1 93380
Affinity Capture-MS Homo sapiens
153 ME2 4200
Proximity Label-MS Homo sapiens
154 JAK3 3718
Affinity Capture-MS Homo sapiens
155 GFM1 85476
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
156 TEFM  
Proximity Label-MS Homo sapiens
157 C1QBP 708
Proximity Label-MS Homo sapiens
158 ATP5C1 509
Co-fractionation Homo sapiens
159 CKAP4 10970
Proximity Label-MS Homo sapiens
160 Smn1 20595
Affinity Capture-MS Mus musculus
161 MRPS9 64965
Proximity Label-MS Homo sapiens
162 GLRX5 51218
Co-fractionation Homo sapiens
163 MRPS27 23107
Proximity Label-MS Homo sapiens
164 NDUFS1 4719
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
165 MARCKS 4082
Proximity Label-MS Homo sapiens
166 LAP3 51056
Co-fractionation Homo sapiens
167 UQCRB 7381
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
168 PYCR1 5831
Proximity Label-MS Homo sapiens
169 DEGS1  
Affinity Capture-MS Homo sapiens
170 LRPPRC 10128
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
171 CAPZB 832
Affinity Capture-MS Homo sapiens
172 NDUFB9 4715
Proximity Label-MS Homo sapiens
173 NDUFS3 4722
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
174 NDUFB8 4714
Proximity Label-MS Homo sapiens
175 SARS2 54938
Proximity Label-MS Homo sapiens
176 SDHB 6390
Co-fractionation Homo sapiens
177 TIMMDC1  
Proximity Label-MS Homo sapiens
178 HINT2 84681
Proximity Label-MS Homo sapiens
179 NUP210 23225
Proximity Label-MS Homo sapiens
180 PIGH  
Affinity Capture-MS Homo sapiens
181 COX7B2  
Affinity Capture-MS Homo sapiens
182 C20orf24  
Co-fractionation Homo sapiens
183 UBE2Q1 55585
Affinity Capture-MS Homo sapiens
184 BCAP29 55973
Co-fractionation Homo sapiens
185 NDUFV1 4723
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
186 CALR 811
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
187 CHCHD6 84303
Proximity Label-MS Homo sapiens
188 ESYT2 57488
Proximity Label-MS Homo sapiens
189 COX1 4512
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
190 CPOX 1371
Proximity Label-MS Homo sapiens
191 UQCRQ 27089
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
192 MDH2 4191
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
193 UBR4 23352
Proximity Label-MS Homo sapiens
194 ATAD3B 83858
Proximity Label-MS Homo sapiens
195 SAMM50 25813
Proximity Label-MS Homo sapiens
196 FASTKD5  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
197 NDUFB7 4713
Co-fractionation Homo sapiens
198 TMEM165 55858
Proximity Label-MS Homo sapiens
199 CHCHD3 54927
Proximity Label-MS Homo sapiens
200 DIABLO 56616
Proximity Label-MS Homo sapiens
201 RPA4  
Proximity Label-MS Homo sapiens
202 ACTB 60
Co-fractionation Homo sapiens
203 COA7  
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
204 COX7B 1349
Co-fractionation Homo sapiens
205 UQCRH 7388
Affinity Capture-MS Homo sapiens
206 MYL12A 10627
Co-fractionation Homo sapiens
207 TMEM70  
Proximity Label-MS Homo sapiens
208 DUSP1  
Affinity Capture-MS Homo sapiens
209 GPAA1 8733
Affinity Capture-MS Homo sapiens
210 SLC25A12 8604
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
211 MINOS1  
Co-fractionation Homo sapiens
212 CLPP 8192
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
213 COX6A1  
Affinity Capture-MS Homo sapiens
214 COX6B1 1340
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
215 CORO1C 23603
Co-fractionation Homo sapiens
216 OCIAD1 54940
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
217 GRAMD1A  
Proximity Label-MS Homo sapiens
218 CRAT 1384
Affinity Capture-MS Homo sapiens
219 P4HB 5034
Proximity Label-MS Homo sapiens
220 LACTB2 51110
Co-fractionation Homo sapiens
221 DNAJC10 54431
Proximity Label-MS Homo sapiens
222 CORO1A 11151
Affinity Capture-MS Homo sapiens
223 HYOU1 10525
Proximity Label-MS Homo sapiens
224 CLPB 81570
Proximity Label-MS Homo sapiens
225 HAX1  
Proximity Label-MS Homo sapiens
226 MAGT1 84061
Co-fractionation Homo sapiens
227 TPM3 7170
Co-fractionation Homo sapiens
228 IMMT 10989
Proximity Label-MS Homo sapiens
229 MBOAT7 79143
Affinity Capture-MS Homo sapiens
230 DNAJC4  
Proximity Label-MS Homo sapiens
231 PHB2 11331
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
232 TSFM 10102
Proximity Label-MS Homo sapiens
233 NDUFAF2  
Proximity Label-MS Homo sapiens
234 ICT1 3396
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
235 LONP1 9361
Proximity Label-MS Homo sapiens
236 PDHA1 5160
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
237 ADCK2  
Proximity Label-MS Homo sapiens
238 GNB1 2782
Co-fractionation Homo sapiens
239 DDX58 23586
Affinity Capture-RNA Homo sapiens
240 SMIM12  
Proximity Label-MS Homo sapiens
241 NDUFS8 4728
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
242 MRPS18B 28973
Proximity Label-MS Homo sapiens
243 TBRG4 9238
Proximity Label-MS Homo sapiens
244 AARS2  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
245 PRDX6 9588
Co-fractionation Homo sapiens
246 TMEM38B  
Affinity Capture-MS Homo sapiens
247 COX7C 1350
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
248 RAC1 5879
Affinity Capture-MS Homo sapiens
249 VDAC3 7419
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
250 MRPS22 56945
Proximity Label-MS Homo sapiens
251 MGST3 4259
Co-fractionation Homo sapiens
252 TIMM44 10469
Proximity Label-MS Homo sapiens
253 UBE2H 7328
Affinity Capture-MS Homo sapiens
254 RIT1 6016
Negative Genetic Homo sapiens
255 VAPA 9218
Co-fractionation Homo sapiens
256 TRUB2  
Proximity Label-MS Homo sapiens
257 MRPL37 51253
Proximity Label-MS Homo sapiens
258 ETFB 2109
Proximity Label-MS Homo sapiens
259 TRIM55  
Two-hybrid Homo sapiens
260 DNAJC15  
Proximity Label-MS Homo sapiens
261 APP 351
Reconstituted Complex Homo sapiens
262 TOMM22 56993
Co-fractionation Homo sapiens
263 HADH 3033
Co-fractionation Homo sapiens
264 KIAA1429 25962
Affinity Capture-MS Homo sapiens
265 ATP5D 513
Co-fractionation Homo sapiens
266 TFAM 7019
Co-fractionation Homo sapiens
267 KLF8  
Affinity Capture-MS Homo sapiens
268 CKMT1A 548596
Proximity Label-MS Homo sapiens
269 COA3 28958
Affinity Capture-Western Homo sapiens
270 DDOST 1650
Co-fractionation Homo sapiens
271 MRPS26 64949
Proximity Label-MS Homo sapiens
272 SURF1  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
273 ATP5O 539
Co-fractionation Homo sapiens
274 EXD2  
Proximity Label-MS Homo sapiens
275 SLC25A25  
Proximity Label-MS Homo sapiens
276 ATP5H 10476
Co-fractionation Homo sapiens
277 SSR3 6747
Co-fractionation Homo sapiens
278 FAF2 23197
Affinity Capture-MS Homo sapiens
279 DAP3 7818
Proximity Label-MS Homo sapiens
280 APOO 79135
Proximity Label-MS Homo sapiens
281 NDUFS4 4724
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
282 COX15 1355
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
283 TMEM126A 84233
Proximity Label-MS Homo sapiens
284 MRPS34 65993
Proximity Label-MS Homo sapiens
285 HSP90B1 7184
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
286 MRPS28  
Proximity Label-MS Homo sapiens
287 PTCD3 55037
Proximity Label-MS Homo sapiens
288 HSCB 150274
Proximity Label-MS Homo sapiens
289 VCP 7415
Co-fractionation Homo sapiens
290 OPA1 4976
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
291 TARS2 80222
Proximity Label-MS Homo sapiens
292 GANAB 23193
Proximity Label-MS Homo sapiens
293 ERAL1  
Proximity Label-MS Homo sapiens
294 DNAJC30  
Proximity Label-MS Homo sapiens
295 CLIC4 25932
Co-fractionation Homo sapiens
296 NIPSNAP1 8508
Co-fractionation Homo sapiens
297 ATP5B 506
Co-fractionation Homo sapiens
298 RHBDD1 84236
Affinity Capture-MS Homo sapiens
299 COX5B 1329
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
300 GFER  
Proximity Label-MS Homo sapiens
301 MRPL21 219927
Proximity Label-MS Homo sapiens
302 FANCD2  
Affinity Capture-MS Homo sapiens
303 NDUFB10 4716
Proximity Label-MS Homo sapiens
304 NDUFA9 4704
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
305 LETM1 3954
Proximity Label-MS Homo sapiens
306 UQCRC2 7385
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
307 CTNNB1 1499
Co-fractionation Homo sapiens
308 C2orf47  
Proximity Label-MS Homo sapiens
309 NFS1 9054
Proximity Label-MS Homo sapiens
310 PDIA3 2923
Proximity Label-MS Homo sapiens
311 ELAC2 60528
Proximity Label-MS Homo sapiens
312 PYCR2 29920
Proximity Label-MS Homo sapiens
313 ECHS1 1892
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
314 FKBP5 2289
Cross-Linking-MS (XL-MS) Homo sapiens
315 YME1L1 10730
Proximity Label-MS Homo sapiens
316 NDUFB3 4709
Co-fractionation Homo sapiens
317 APOOL 139322
Proximity Label-MS Homo sapiens
318 ATP6V1A 523
Co-fractionation Homo sapiens
319 NDUFA6  
Proximity Label-MS Homo sapiens
320 VDAC1 7416
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
321 KRAS 3845
Negative Genetic Homo sapiens
322 MTHFD1L 25902
Proximity Label-MS Homo sapiens
323 GLUD1 2746
Proximity Label-MS Homo sapiens
324 MRPS2 51116
Proximity Label-MS Homo sapiens
325 TUBG1 7283
Affinity Capture-MS Homo sapiens
326 PDIA4 9601
Proximity Label-MS Homo sapiens
327 PIGA  
Affinity Capture-MS Homo sapiens
328 GLDC 2731
Affinity Capture-MS Homo sapiens
329 MRPS31  
Proximity Label-MS Homo sapiens
330 MRPL43 84545
Proximity Label-MS Homo sapiens
331 DNAJA3 9093
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
332 NDUFS7 374291
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
333 PDHB 5162
Co-fractionation Homo sapiens
334 C21orf33  
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
335 SFXN1 94081
Proximity Label-MS Homo sapiens
336 LRPAP1 4043
Proximity Label-MS Homo sapiens
337 TOMM5  
Co-fractionation Homo sapiens
338 C19orf52  
Proximity Label-MS Homo sapiens
339 COX7A2 1347
Affinity Capture-MS Homo sapiens
340 NDUFAF4 29078
Proximity Label-MS Homo sapiens
341 NDUFB11 54539
Proximity Label-MS Homo sapiens
342 METTL17  
Proximity Label-MS Homo sapiens
343 COX3 4514
Affinity Capture-MS Homo sapiens
344 ALDOA 226
Co-fractionation Homo sapiens
345 ECSIT 51295
Proximity Label-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here