Gene description for DGCR2
Gene name DiGeorge syndrome critical region gene 2
Gene symbol DGCR2
Other names/aliases DGS-C
IDD
LAN
SEZ-12
Species Homo sapiens
 Database cross references - DGCR2
ExoCarta ExoCarta_9993
Vesiclepedia VP_9993
Entrez Gene 9993
HGNC 2845
MIM 600594
UniProt P98153  
 DGCR2 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for DGCR2
Molecular Function
    carbohydrate binding GO:0030246 IEA
Biological Process
    cell adhesion GO:0007155 IEA
    animal organ morphogenesis GO:0009887 TAS
    cognition GO:0050890 IMP
Subcellular Localization
    membrane GO:0016020 IBA
 Experiment description of studies that identified DGCR2 in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for DGCR2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DEPDC1  
Affinity Capture-MS Homo sapiens
2 SLIRP 81892
Affinity Capture-MS Homo sapiens
3 UTP15 84135
Affinity Capture-MS Homo sapiens
4 DNAJC11 55735
Proximity Label-MS Homo sapiens
5 RINT1 60561
Affinity Capture-MS Homo sapiens
6 DOCK4 9732
Affinity Capture-MS Homo sapiens
7 WWP1 11059
Affinity Capture-MS Homo sapiens
8 NOP9 161424
Affinity Capture-MS Homo sapiens
9 CFC1  
Affinity Capture-MS Homo sapiens
10 ATP12A 479
Affinity Capture-MS Homo sapiens
11 ECEL1  
Affinity Capture-MS Homo sapiens
12 FAM168A  
Affinity Capture-MS Homo sapiens
13 URB2  
Affinity Capture-MS Homo sapiens
14 ST3GAL2 6483
Affinity Capture-MS Homo sapiens
15 INTS1 26173
Affinity Capture-MS Homo sapiens
16 LTN1 26046
Affinity Capture-MS Homo sapiens
17 PRKDC 5591
Affinity Capture-MS Homo sapiens
18 DNAJB9 4189
Affinity Capture-MS Homo sapiens
19 PI4KA 5297
Affinity Capture-MS Homo sapiens
20 FAM126A 84668
Affinity Capture-MS Homo sapiens
21 RPS6KA3 6197
Affinity Capture-MS Homo sapiens
22 HLA-DRB3 3125
Affinity Capture-MS Homo sapiens
23 SLC39A10 57181
Affinity Capture-MS Homo sapiens
24 PPP2R5D 5528
Affinity Capture-MS Homo sapiens
25 MDN1 23195
Affinity Capture-MS Homo sapiens
26 HTR3C  
Affinity Capture-MS Homo sapiens
27 VEGFB  
Affinity Capture-MS Homo sapiens
28 CLEC2B  
Affinity Capture-MS Homo sapiens
29 KLRC1  
Affinity Capture-MS Homo sapiens
30 TBC1D15 64786
Affinity Capture-MS Homo sapiens
31 LIPG 9388
Affinity Capture-MS Homo sapiens
32 UTP20 27340
Affinity Capture-MS Homo sapiens
33 SMAD5 4090
Affinity Capture-MS Homo sapiens
34 RPS6KA2  
Affinity Capture-MS Homo sapiens
35 BTNL2  
Affinity Capture-MS Homo sapiens
36 TMEM106A  
Affinity Capture-MS Homo sapiens
37 NEDD4 4734
Affinity Capture-MS Homo sapiens
38 HLA-G 3135
Affinity Capture-MS Homo sapiens
39 TSC2 7249
Affinity Capture-MS Homo sapiens
40 ZDHHC17 23390
Affinity Capture-MS Homo sapiens
41 IL9R  
Affinity Capture-MS Homo sapiens
42 SC5D 6309
Affinity Capture-MS Homo sapiens
43 CENPH  
Affinity Capture-MS Homo sapiens
44 ATP8B2 57198
Affinity Capture-MS Homo sapiens
45 CNOT11 55571
Affinity Capture-MS Homo sapiens
46 WWP2 11060
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 SAV1  
Affinity Capture-MS Homo sapiens
48 NLRX1 79671
Affinity Capture-MS Homo sapiens
49 XPO5 57510
Affinity Capture-MS Homo sapiens
50 CHPT1  
Affinity Capture-MS Homo sapiens
51 NCAPD3 23310
Affinity Capture-MS Homo sapiens
52 TAMM41  
Affinity Capture-MS Homo sapiens
53 SDF2L1 23753
Affinity Capture-MS Homo sapiens
54 TYK2 7297
Affinity Capture-MS Homo sapiens
55 ATP9A 10079
Affinity Capture-MS Homo sapiens
56 TIGD5  
Affinity Capture-MS Homo sapiens
57 LEMD2 221496
Affinity Capture-MS Homo sapiens
58 SLC9A1 6548
Affinity Capture-MS Homo sapiens
59 INTS7  
Affinity Capture-MS Homo sapiens
60 ITM2C 81618
Affinity Capture-MS Homo sapiens
61 HLA-DRB5 3127
Affinity Capture-MS Homo sapiens
62 STXBP4 252983
Affinity Capture-MS Homo sapiens
63 ASCC2 84164
Affinity Capture-MS Homo sapiens
64 GML  
Affinity Capture-MS Homo sapiens
65 CELA2B  
Affinity Capture-MS Homo sapiens
66 ATP2B4 493
Affinity Capture-MS Homo sapiens
67 LMBR1  
Affinity Capture-MS Homo sapiens
68 YAP1 10413
Affinity Capture-MS Homo sapiens
69 LYPD4  
Affinity Capture-MS Homo sapiens
70 TIMELESS  
Affinity Capture-MS Homo sapiens
71 ZACN  
Affinity Capture-MS Homo sapiens
72 GNL3L 54552
Affinity Capture-MS Homo sapiens
73 CCDC85C  
Affinity Capture-MS Homo sapiens
74 UPK2 7379
Affinity Capture-MS Homo sapiens
75 SPPL3  
Affinity Capture-MS Homo sapiens
76 TPCN1 53373
Affinity Capture-MS Homo sapiens
77 HNRNPD 3184
Two-hybrid Homo sapiens
78 DNAJB14  
Proximity Label-MS Homo sapiens
79 LAPTM4B  
Affinity Capture-MS Homo sapiens
80 ASCC3 10973
Affinity Capture-MS Homo sapiens
81 SGPL1 8879
Affinity Capture-MS Homo sapiens
82 CANX 821
Affinity Capture-MS Homo sapiens
83 NDFIP2 54602
Affinity Capture-MS Homo sapiens
84 SLC39A6 25800
Affinity Capture-MS Homo sapiens
85 DNAJC2 27000
Affinity Capture-MS Homo sapiens
86 NCAPH2  
Affinity Capture-MS Homo sapiens
87 IQCB1  
Affinity Capture-MS Homo sapiens
88 ARFGEF1 10565
Affinity Capture-MS Homo sapiens
89 IFRD1 3475
Affinity Capture-MS Homo sapiens
90 MZT2B 80097
Affinity Capture-MS Homo sapiens
91 CERK 64781
Affinity Capture-MS Homo sapiens
92 SLC26A2 1836
Affinity Capture-MS Homo sapiens
93 POM121  
Affinity Capture-MS Homo sapiens
94 KLRD1  
Affinity Capture-MS Homo sapiens
95 EGFL7 51162
Affinity Capture-MS Homo sapiens
96 LYZL1  
Affinity Capture-MS Homo sapiens
97 MYO19  
Affinity Capture-MS Homo sapiens
98 SMAD1 4086
Affinity Capture-MS Homo sapiens
99 ZW10 9183
Affinity Capture-MS Homo sapiens
100 DNAJC18  
Affinity Capture-MS Homo sapiens
101 C4orf29 80167
Affinity Capture-MS Homo sapiens
102 KIF7 374654
Affinity Capture-MS Homo sapiens
103 CST11  
Affinity Capture-MS Homo sapiens
104 RBM14-RBM4 100526737
Affinity Capture-MS Homo sapiens
105 PSCA 8000
Affinity Capture-MS Homo sapiens
106 TRAPPC12 51112
Affinity Capture-MS Homo sapiens
107 DDRGK1 65992
Affinity Capture-MS Homo sapiens
108 DNASE1L1 1774
Affinity Capture-MS Homo sapiens
109 NCAPG2 54892
Affinity Capture-MS Homo sapiens
110 DYM  
Affinity Capture-MS Homo sapiens
111 KIDINS220 57498
Affinity Capture-MS Homo sapiens
112 HEATR1 55127
Affinity Capture-MS Homo sapiens
113 LEMD3  
Affinity Capture-MS Homo sapiens
114 OSBPL8 114882
Affinity Capture-MS Homo sapiens
115 NEDD4L 23327
Affinity Capture-MS Homo sapiens
116 ATP2B3 492
Affinity Capture-MS Homo sapiens
117 LYZL2  
Affinity Capture-MS Homo sapiens
118 ADAM30 11085
Affinity Capture-MS Homo sapiens
119 DEPDC1B 55789
Affinity Capture-MS Homo sapiens
120 HMGCR  
Affinity Capture-MS Homo sapiens
121 ARV1  
Affinity Capture-MS Homo sapiens
122 SLC25A16  
Affinity Capture-MS Homo sapiens
123 MUL1  
Affinity Capture-MS Homo sapiens
124 NAAA  
Affinity Capture-MS Homo sapiens
125 PDS5B 23047
Affinity Capture-MS Homo sapiens
126 TMEM57  
Affinity Capture-MS Homo sapiens
127 TBRG4 9238
Affinity Capture-MS Homo sapiens
128 DNAJC19 131118
Proximity Label-MS Homo sapiens
129 RHOBTB3 22836
Affinity Capture-MS Homo sapiens
130 RGPD2  
Affinity Capture-MS Homo sapiens
131 GTPBP6  
Affinity Capture-MS Homo sapiens
132 WWOX 51741
Affinity Capture-MS Homo sapiens
133 PIGA  
Affinity Capture-MS Homo sapiens
134 KIAA1586  
Affinity Capture-MS Homo sapiens
135 ADAM33 80332
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
136 LRPPRC 10128
Affinity Capture-MS Homo sapiens
137 XPR1 9213
Affinity Capture-MS Homo sapiens
138 ATP5G3 518
Affinity Capture-MS Homo sapiens
139 HBA2 3040
Affinity Capture-MS Homo sapiens
140 TUBGCP3 10426
Affinity Capture-MS Homo sapiens
141 DNAJA3 9093
Proximity Label-MS Homo sapiens
142 ZDHHC13 54503
Affinity Capture-MS Homo sapiens
143 C19orf25  
Affinity Capture-MS Homo sapiens
144 NCR3  
Affinity Capture-MS Homo sapiens
145 KIAA1033 23325
Affinity Capture-MS Homo sapiens
146 ELMO2 63916
Affinity Capture-MS Homo sapiens
147 GORASP1 64689
Affinity Capture-MS Homo sapiens
148 KIRREL 55243
Affinity Capture-MS Homo sapiens
149 SFTPC  
Affinity Capture-MS Homo sapiens
150 HOXD13  
Affinity Capture-MS Homo sapiens
151 NF1 4763
Affinity Capture-MS Homo sapiens
152 OGFOD3 79701
Affinity Capture-MS Homo sapiens
153 DDIT3 1649
Two-hybrid Homo sapiens
154 DSTYK 25778
Affinity Capture-MS Homo sapiens
155 SIRPD  
Affinity Capture-MS Homo sapiens
156 BRICD5  
Affinity Capture-MS Homo sapiens
157 TTYH3 80727
Affinity Capture-MS Homo sapiens
158 DNAJC5B  
Proximity Label-MS Homo sapiens
159 UGT1A7 54577
Affinity Capture-MS Homo sapiens
160 ATP2B2 491
Affinity Capture-MS Homo sapiens
161 ACSL3 2181
Affinity Capture-MS Homo sapiens
162 MIPEP  
Affinity Capture-MS Homo sapiens
163 PTPRK 5796
Affinity Capture-MS Homo sapiens
164 ASIC4  
Affinity Capture-MS Homo sapiens
165 P2RX2  
Affinity Capture-MS Homo sapiens
166 SMURF2 64750
Two-hybrid Homo sapiens
167 HLA-DRB1 3123
Affinity Capture-MS Homo sapiens
168 PLD6  
Affinity Capture-MS Homo sapiens
169 HECW2  
Affinity Capture-MS Homo sapiens
170 TIMP3 7078
Affinity Capture-MS Homo sapiens
171 SPTLC2 9517
Affinity Capture-MS Homo sapiens
172 DDX28  
Affinity Capture-MS Homo sapiens
173 TTC7B 145567
Affinity Capture-MS Homo sapiens
174 UBA52 7311
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which DGCR2 is involved
No pathways found





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