Gene description for MRPS18B
Gene name mitochondrial ribosomal protein S18B
Gene symbol MRPS18B
Other names/aliases C6orf14
HSPC183
HumanS18a
MRP-S18-2
MRPS18-2
PTD017
S18amt
Species Homo sapiens
 Database cross references - MRPS18B
ExoCarta ExoCarta_28973
Vesiclepedia VP_28973
Entrez Gene 28973
HGNC 14516
MIM 611982
UniProt Q9Y676  
 MRPS18B identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for MRPS18B
Molecular Function
    structural constituent of ribosome GO:0003735 ISS
    structural constituent of ribosome GO:0003735 NAS
    protein binding GO:0005515 IPI
Biological Process
    translation GO:0006412 NAS
    mitochondrial translation GO:0032543 ISS
    mitochondrial translation GO:0032543 NAS
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 IDA
    mitochondrial inner membrane GO:0005743 NAS
    mitochondrial inner membrane GO:0005743 TAS
    mitochondrial small ribosomal subunit GO:0005763 IDA
    mitochondrial small ribosomal subunit GO:0005763 ISS
    mitochondrial small ribosomal subunit GO:0005763 NAS
    cell junction GO:0030054 IDA
 Experiment description of studies that identified MRPS18B in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for MRPS18B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SEC22B 9554
Two-hybrid Homo sapiens
2 UBE2H 7328
Affinity Capture-MS Homo sapiens
3 PDHA1 5160
Proximity Label-MS Homo sapiens
4 MRPS27 23107
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 SLIRP 81892
Proximity Label-MS Homo sapiens
6 H1FNT  
Affinity Capture-MS Homo sapiens
7 SLC35A1 10559
Two-hybrid Homo sapiens
8 QARS 5859
Co-fractionation Homo sapiens
9 BHLHA15  
Affinity Capture-MS Homo sapiens
10 TUSC5  
Two-hybrid Homo sapiens
11 Ybx1 22608
Affinity Capture-MS Mus musculus
12 KLF8  
Proximity Label-MS Homo sapiens
13 MTG2  
Proximity Label-MS Homo sapiens
14 NGRN  
Proximity Label-MS Homo sapiens
15 RPL10 6134
Affinity Capture-MS Homo sapiens
16 CHCHD1  
Proximity Label-MS Homo sapiens
17 UBC 7316
Affinity Capture-MS Homo sapiens
18 KARS 3735
Co-fractionation Homo sapiens
19 CAND1 55832
Affinity Capture-MS Homo sapiens
20 RPUSD4 84881
Proximity Label-MS Homo sapiens
21 PARK7 11315
Affinity Capture-MS Homo sapiens
22 DNAJC15  
Proximity Label-MS Homo sapiens
23 MTRF1  
Proximity Label-MS Homo sapiens
24 GFM2 84340
Proximity Label-MS Homo sapiens
25 LRP10 26020
Two-hybrid Homo sapiens
26 CCDC90B  
Proximity Label-MS Homo sapiens
27 LRPPRC 10128
Proximity Label-MS Homo sapiens
28 RPS9 6203
Affinity Capture-MS Homo sapiens
29 KIF20A 10112
Affinity Capture-MS Homo sapiens
30 TRUB2  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 HNRNPAB 3182
Co-fractionation Homo sapiens
32 ZBTB2 57621
Affinity Capture-MS Homo sapiens
33 MCU 90550
Proximity Label-MS Homo sapiens
34 CRYZ 1429
Proximity Label-MS Homo sapiens
35 TFAM 7019
Proximity Label-MS Homo sapiens
36 RBM3 5935
Affinity Capture-MS Homo sapiens
37 PMPCA 23203
Proximity Label-MS Homo sapiens
38 PCK1 5105
Affinity Capture-MS Homo sapiens
39 C8orf82  
Proximity Label-MS Homo sapiens
40 PHB2 11331
Reconstituted Complex Homo sapiens
41 NFKBIL1  
Affinity Capture-MS Homo sapiens
42 MRPS5 64969
Affinity Capture-MS Homo sapiens
43 HINT2 84681
Proximity Label-MS Homo sapiens
44 MRPS23 51649
Affinity Capture-MS Homo sapiens
45 MRPS24 64951
Affinity Capture-MS Homo sapiens
46 ZNF460  
Affinity Capture-MS Homo sapiens
47 DDRGK1 65992
Affinity Capture-MS Homo sapiens
48 KLF15  
Affinity Capture-MS Homo sapiens
49 EWSR1 2130
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
50 YBX1 4904
Affinity Capture-MS Homo sapiens
51 MRPS26 64949
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
52 SURF1  
Proximity Label-MS Homo sapiens
53 SRSF3 6428
Affinity Capture-MS Homo sapiens
54 PTCD1 26024
Affinity Capture-MS Homo sapiens
55 EXD2  
Proximity Label-MS Homo sapiens
56 TULP3 7289
Affinity Capture-MS Homo sapiens
57 ERAL1  
Affinity Capture-MS Homo sapiens
58 KLF4  
Affinity Capture-MS Homo sapiens
59 E4F1  
Affinity Capture-MS Homo sapiens
60 EXOSC6 118460
Two-hybrid Homo sapiens
61 TLX3  
Proximity Label-MS Homo sapiens
62 PMPCB 9512
Proximity Label-MS Homo sapiens
63 TACO1  
Proximity Label-MS Homo sapiens
64 FASTKD2  
Proximity Label-MS Homo sapiens
65 MTIF2 4528
Proximity Label-MS Homo sapiens
66 FAM120A 23196
Affinity Capture-MS Homo sapiens
67 MTERF3  
Proximity Label-MS Homo sapiens
68 LIN28A  
Affinity Capture-MS Homo sapiens
69 MDH2 4191
Proximity Label-MS Homo sapiens
70 KLF16  
Affinity Capture-MS Homo sapiens
71 MRPS25 64432
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
72 DLD 1738
Affinity Capture-MS Homo sapiens
73 C6orf203  
Proximity Label-MS Homo sapiens
74 ZNF133  
Affinity Capture-MS Homo sapiens
75 COX15 1355
Proximity Label-MS Homo sapiens
76 FASTKD5  
Proximity Label-MS Homo sapiens
77 METTL15  
Proximity Label-MS Homo sapiens
78 IGFBP5 3488
Two-hybrid Homo sapiens
79 PARK2  
Affinity Capture-MS Homo sapiens
80 MRPS34 65993
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 SIRT3  
Affinity Capture-MS Homo sapiens
82 ERBB3 2065
Affinity Capture-MS Homo sapiens
83 PTCD3 55037
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
84 TRA2A 29896
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
85 YBX2 51087
Affinity Capture-MS Homo sapiens
86 TUBGCP4 27229
Affinity Capture-MS Homo sapiens
87 USP36  
Affinity Capture-MS Homo sapiens
88 TUFM 7284
Proximity Label-MS Homo sapiens
89 ZBTB48  
Affinity Capture-MS Homo sapiens
90 Pabpc1 18458
Affinity Capture-MS Mus musculus
91 HSCB 150274
Proximity Label-MS Homo sapiens
92 HIST1H2AM 8336
Affinity Capture-MS Homo sapiens
93 UBR5 51366
Co-fractionation Homo sapiens
94 MYH9 4627
Co-fractionation Homo sapiens
95 VCP 7415
Affinity Capture-MS Homo sapiens
96 MRPS6  
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
97 CCDC109B 55013
Proximity Label-MS Homo sapiens
98 DDX55  
Affinity Capture-MS Homo sapiens
99 MOV10 4343
Affinity Capture-RNA Homo sapiens
100 CD81 975
Two-hybrid Homo sapiens
101 FBXL6  
Affinity Capture-MS Homo sapiens
102 TNFRSF10C  
Two-hybrid Homo sapiens
103 NOA1  
Affinity Capture-MS Homo sapiens
104 MTFMT  
Proximity Label-MS Homo sapiens
105 MRPL11 65003
Proximity Label-MS Homo sapiens
106 MTRF1L  
Proximity Label-MS Homo sapiens
107 DNAJC30  
Proximity Label-MS Homo sapiens
108 NDUFAF7  
Affinity Capture-MS Homo sapiens
109 TMEM70  
Proximity Label-MS Homo sapiens
110 Ksr1  
Affinity Capture-MS Mus musculus
111 FGF13  
Affinity Capture-MS Homo sapiens
112 MRPS33  
Affinity Capture-MS Homo sapiens
113 GAPDHS 26330
Affinity Capture-MS Homo sapiens
114 COX4I1 1327
Proximity Label-MS Homo sapiens
115 TEFM  
Proximity Label-MS Homo sapiens
116 TLX2  
Proximity Label-MS Homo sapiens
117 LAT 27040
Two-hybrid Homo sapiens
118 OTC 5009
Proximity Label-MS Homo sapiens
119 RBM39 9584
Affinity Capture-MS Homo sapiens
120 BMP10  
Two-hybrid Homo sapiens
121 DNAJC21  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
122 MRRF  
Proximity Label-MS Homo sapiens
123 ABT1 29777
Affinity Capture-MS Homo sapiens
124 MRPS12  
Proximity Label-MS Homo sapiens
125 AURKAIP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
126 DAP3 7818
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
127 TLX1  
Affinity Capture-MS Homo sapiens
128 ZFPL1 7542
Two-hybrid Homo sapiens
129 MRPS35 60488
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
130 RC3H2  
Affinity Capture-MS Homo sapiens
131 Wdr5  
Affinity Capture-MS Mus musculus
132 MRPS11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
133 MTIF3  
Proximity Label-MS Homo sapiens
134 RPL35 11224
Affinity Capture-MS Homo sapiens
135 TMED8 283578
Two-hybrid Homo sapiens
136 MRPS7 51081
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
137 SRSF5 6430
Affinity Capture-MS Homo sapiens
138 MRPS14  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
139 NPM3 10360
Affinity Capture-MS Homo sapiens
140 TMEM128  
Two-hybrid Homo sapiens
141 CUL3 8452
Affinity Capture-MS Homo sapiens
142 RMND1 55005
Proximity Label-MS Homo sapiens
143 ZNF770 54989
Affinity Capture-MS Homo sapiens
144 TOP3A  
Affinity Capture-MS Homo sapiens
145 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
146 DHX30 22907
Proximity Label-MS Homo sapiens
147 MYC  
Affinity Capture-MS Homo sapiens
148 NPM1 4869
Affinity Capture-MS Homo sapiens
149 C17orf80 55028
Proximity Label-MS Homo sapiens
150 SOX15  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
151 Rnf2  
Reconstituted Complex Mus musculus
152 C12orf65  
Proximity Label-MS Homo sapiens
153 MYCN  
Affinity Capture-MS Homo sapiens
154 CEP250 11190
Affinity Capture-MS Homo sapiens
155 CBX6  
Affinity Capture-MS Homo sapiens
156 MTG1  
Proximity Label-MS Homo sapiens
157 PSPC1 55269
Affinity Capture-MS Homo sapiens
158 CLEC1A  
Two-hybrid Homo sapiens
159 FUS 2521
Co-fractionation Homo sapiens
160 KIAA0391  
Affinity Capture-MS Homo sapiens
161 TSFM 10102
Proximity Label-MS Homo sapiens
162 ACAD9 28976
Proximity Label-MS Homo sapiens
163 P3H3 10536
Affinity Capture-MS Homo sapiens
164 VWA8 23078
Proximity Label-MS Homo sapiens
165 SYS1  
Two-hybrid Homo sapiens
166 MRPS17 51373
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
167 ENTHD2  
Affinity Capture-MS Homo sapiens
168 ZC3H3  
Affinity Capture-MS Homo sapiens
169 MCUR1 63933
Proximity Label-MS Homo sapiens
170 RBMS2 5939
Affinity Capture-MS Homo sapiens
171 ZNF263  
Affinity Capture-MS Homo sapiens
172 SOX2  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
173 HECTD1 25831
Affinity Capture-MS Homo sapiens
174 DNAJC4  
Proximity Label-MS Homo sapiens
175 DEPDC1B 55789
Affinity Capture-MS Homo sapiens
176 DNAJC28  
Proximity Label-MS Homo sapiens
177 CS 1431
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
178 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
179 Prkci  
Affinity Capture-MS Mus musculus
180 METTL17  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
181 AUH 549
Proximity Label-MS Homo sapiens
182 MRPS2 51116
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
183 MIP  
Two-hybrid Homo sapiens
184 TBRG4 9238
Proximity Label-MS Homo sapiens
185 POLG  
Affinity Capture-MS Homo sapiens
186 DNAJC19 131118
Proximity Label-MS Homo sapiens
187 MCAT 27349
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
188 TP53 7157
Affinity Capture-MS Homo sapiens
189 PRR3  
Affinity Capture-MS Homo sapiens
190 ICT1 3396
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
191 MRPS28  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
192 LONP1 9361
Proximity Label-MS Homo sapiens
193 SRP14 6727
Affinity Capture-MS Homo sapiens
194 MRPS18C  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
195 MRPS31  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
196 BYSL 705
Affinity Capture-MS Homo sapiens
197 TMEM120B  
Two-hybrid Homo sapiens
198 TUBGCP3 10426
Affinity Capture-MS Homo sapiens
199 DNAJA3 9093
Proximity Label-MS Homo sapiens
200 MRPS15  
Affinity Capture-MS Homo sapiens
201 MRPS10 55173
Affinity Capture-MS Homo sapiens
202 GLI4  
Affinity Capture-MS Homo sapiens
203 C21orf33  
Proximity Label-MS Homo sapiens
204 MRPS21  
Affinity Capture-MS Homo sapiens
205 SSBP1 6742
Proximity Label-MS Homo sapiens
206 KLF12  
Affinity Capture-MS Homo sapiens
207 KLF5  
Proximity Label-MS Homo sapiens
208 FASTKD3  
Proximity Label-MS Homo sapiens
209 NEIL1  
Affinity Capture-MS Homo sapiens
210 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
211 GFM1 85476
Proximity Label-MS Homo sapiens
212 NEDD1 121441
Affinity Capture-MS Homo sapiens
213 MRPS9 64965
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
214 C19orf52  
Proximity Label-MS Homo sapiens
215 RPUSD3  
Proximity Label-MS Homo sapiens
216 TRMT10B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
217 MRPS16  
Affinity Capture-MS Homo sapiens
218 GRSF1 2926
Proximity Label-MS Homo sapiens
219 C1QBP 708
Proximity Label-MS Homo sapiens
220 CUL7 9820
Affinity Capture-MS Homo sapiens
221 HNRNPU 3192
Affinity Capture-MS Homo sapiens
222 RC3H1 149041
Affinity Capture-MS Homo sapiens
223 MRPS22 56945
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
224 SRSF7 6432
Affinity Capture-MS Homo sapiens
225 STRBP 55342
Affinity Capture-MS Homo sapiens
226 SUPV3L1 6832
Affinity Capture-MS Homo sapiens
227 DDX28  
Proximity Label-MS Homo sapiens
228 RPL17 6139
Affinity Capture-MS Homo sapiens
229 ZNF17  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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