Gene ontology annotations for EGFR
Experiment description of studies that identified EGFR in exosomes
1
Experiment ID
76
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|GAPDH|HSP90
EV Cytosolic markers
✔
CD81|CD9|CD63|LAMP1|MHCI
EV Membrane markers
✔
HSP90B1
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
20224111
Organism
Homo sapiens
Experiment description
Proteomics analysis of bladder cancer exosomes.
Authors
Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A.
Journal name
MCP
Publication year
2010
Sample
Bladder cancer cells
Sample name
HT1376
Isolation/purification methods
Differential centrifugation Sucrose density gradient
Flotation density
1.10-1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [MALDI TOF/TOF] Western blotting FACS
2
Experiment ID
21
ISEV standards
✔
EM|IEM
EV Biophysical techniques
✔
Alix|TSG101|HSP70
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
PubMed ID
19837982
Organism
Homo sapiens
Experiment description
Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors
Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson
Journal name
MCP
Publication year
2009
Sample
Colorectal cancer cells
Sample name
LIM1215
Isolation/purification methods
Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.10-1.12 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [Orbitrap] Western blotting
3
Experiment ID
201
ISEV standards
✔
EM
EV Biophysical techniques
✔
Alix|TSG101|HSP70
EV Cytosolic markers
✔
CD9
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
22740476
Organism
Homo sapiens
Experiment description
Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4.
Authors
Lim JW, Mathias RA, Kapp EA, Layton MJ, Faux MC, Burgess AW, Ji H, Simpson RJ.
Journal name
Electrophoresis
Publication year
2012
Sample
Colorectal cancer cells
Sample name
SW480
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
4
Experiment ID
189
ISEV standards
✔
EM
EV Biophysical techniques
✘
EV Cytosolic markers
✘
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
19530224
Organism
Homo sapiens
Experiment description
Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors
Chavez-Muñoz C, Kilani RT, Ghahary A.
Journal name
J Cell Physiol
Publication year
2009
Sample
Keratinocytes
Sample name
Keratinocytes - Differentiated
Isolation/purification methods
Differential centrifugation Filtration Sucrose cushion Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
5
Experiment ID
190
ISEV standards
✔
EM
EV Biophysical techniques
✔
HSC70
EV Cytosolic markers
✘
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
19530224
Organism
Homo sapiens
Experiment description
Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors
Chavez-Muñoz C, Kilani RT, Ghahary A.
Journal name
J Cell Physiol
Publication year
2009
Sample
Keratinocytes
Sample name
Keratinocytes - Undifferentiated
Isolation/purification methods
Differential centrifugation Filtration Sucrose cushion Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
6
Experiment ID
254
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
FLOT1|CD81
EV Membrane markers
✘
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Western blotting
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
MNT-1
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
7
Experiment ID
254
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
FLOT1|CD81
EV Membrane markers
✘
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Western blotting
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
MNT-1
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
8
Experiment ID
256
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
FLOT1
EV Membrane markers
✘
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Western blotting
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
501mel
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
9
Experiment ID
257
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
FLOT1
EV Membrane markers
✘
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Western blotting
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
Daju
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
10
Experiment ID
258
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
FLOT1|CD81
EV Membrane markers
✘
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Western blotting
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
SKMEL28
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
11
Experiment ID
259
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
FLOT1
EV Membrane markers
✘
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry Western blotting
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
A375M
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
12
Experiment ID
259
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
FLOT1
EV Membrane markers
✘
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Western blotting
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
A375M
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
13
Experiment ID
260
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
FLOT1|CD81
EV Membrane markers
✘
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry Western blotting
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
1205Lu
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
14
Experiment ID
125
ISEV standards
✘
EV Biophysical techniques
✔
HSC70|GAPDH
EV Cytosolic markers
✔
FLOT2
EV Membrane markers
✔
HSPA5
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Western blotting
PubMed ID
21059916
Organism
Homo sapiens
Experiment description
Human tumor virus utilizes exosomes for intercellular communication.
Authors
Meckes DG Jr, Shair KH, Marquitz AR, Kung CP, Edwards RH, Raab-Traub N.
Journal name
PNAS
Publication year
2010
Sample
Nasopharyngeal carcinoma cells
Sample name
C666
Isolation/purification methods
Differential centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting
15
Experiment ID
211
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
cytochrome c|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
16
Experiment ID
212
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
Cytochrome C|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
17
Experiment ID
104
ISEV standards
✘
EV Biophysical techniques
✔
SDCBP
EV Cytosolic markers
✘
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Western blotting
PubMed ID
21763319
Organism
Homo sapiens
Experiment description
Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells.
Authors
Adamczyk KA, Klein-Scory S, Tehrani MM, Warnken U, Schmiegel W, Schnolzer M, Schwarte-Waldhoff I.
Journal name
LS
Publication year
2011
Sample
Pancreatic cancer cells
Sample name
BxPC3
Isolation/purification methods
Differential centrifugation Filtration Ultrafiltration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting
18
Experiment ID
105
ISEV standards
✘
EV Biophysical techniques
✔
SDCBP
EV Cytosolic markers
✘
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Western blotting
PubMed ID
21763319
Organism
Homo sapiens
Experiment description
Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells.
Authors
Adamczyk KA, Klein-Scory S, Tehrani MM, Warnken U, Schmiegel W, Schnolzer M, Schwarte-Waldhoff I.
Journal name
LS
Publication year
2011
Sample
Pancreatic cancer cells
Sample name
Paca44
Isolation/purification methods
Differential centrifugation Filtration Ultrafiltration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting
19
Experiment ID
106
ISEV standards
✘
EV Biophysical techniques
✔
SDCBP
EV Cytosolic markers
✘
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Western blotting
PubMed ID
21763319
Organism
Homo sapiens
Experiment description
Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells.
Authors
Adamczyk KA, Klein-Scory S, Tehrani MM, Warnken U, Schmiegel W, Schnolzer M, Schwarte-Waldhoff I.
Journal name
LS
Publication year
2011
Sample
Pancreatic cancer cells
Sample name
MiaPaca2
Isolation/purification methods
Differential centrifugation Filtration Ultrafiltration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting
20
Experiment ID
107
ISEV standards
✘
EV Biophysical techniques
✔
SDCBP
EV Cytosolic markers
✘
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Western blotting
PubMed ID
21763319
Organism
Homo sapiens
Experiment description
Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells.
Authors
Adamczyk KA, Klein-Scory S, Tehrani MM, Warnken U, Schmiegel W, Schnolzer M, Schwarte-Waldhoff I.
Journal name
LS
Publication year
2011
Sample
Pancreatic cancer cells
Sample name
A818-4
Isolation/purification methods
Differential centrifugation Filtration Ultrafiltration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting
21
Experiment ID
103
ISEV standards
✘
EV Biophysical techniques
✔
Alix|SDCBP
EV Cytosolic markers
✔
CD63|CD9
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry [Orbitrap] Western blotting
PubMed ID
21763319
Organism
Homo sapiens
Experiment description
Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells.
Authors
Adamczyk KA, Klein-Scory S, Tehrani MM, Warnken U, Schmiegel W, Schnolzer M, Schwarte-Waldhoff I.
Journal name
LS
Publication year
2011
Sample
Pancreatic cancer cells
Sample name
Panc1
Isolation/purification methods
Differential centrifugation Filtration Ultrafiltration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [Orbitrap] Western blotting
22
Experiment ID
275
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|RAB5A
EV Cytosolic markers
✔
CD9|CD82|CD63|CD81
EV Membrane markers
✔
AIF
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25844599
Organism
Homo sapiens
Experiment description
Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors
Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T.
Journal name
Oncotarget
Publication year
2015
Sample
Prostate cancer cells
Sample name
DU145 - Docetaxel sensitive
Isolation/purification methods
Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.12-1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry/Flow cytometry/Western blotting
23
Experiment ID
274
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|RAB5A
EV Cytosolic markers
✔
CD9|CD82|CD63|CD81
EV Membrane markers
✔
AIF
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25844599
Organism
Homo sapiens
Experiment description
Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors
Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T.
Journal name
Oncotarget
Publication year
2015
Sample
Prostate cancer cells
Sample name
DU145 - Docetaxel resistant
Isolation/purification methods
Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.18 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry Flow cytometry Western blotting
24
Experiment ID
29
ISEV standards
✘
EV Biophysical techniques
✘
EV Cytosolic markers
✘
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Western blotting
PubMed ID
19109410
Organism
Homo sapiens
Experiment description
Proteomic and immunologic analyses of brain tumor exosomes.
Authors
Graner MW, Alzate O, Dechkovskaia AM, Keene JD, Sampson JH, Mitchell DA, Bigner DD
Journal name
FASEB
Publication year
2008
Sample
Serum
Sample name
Serum - Brain tumor
Isolation/purification methods
Differential centrifugation Sucrose density gradient
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting
25
Experiment ID
217
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD81|CD9|CD63
EV Membrane markers
✘
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23844026
Organism
Homo sapiens
Experiment description
Characterization of human thymic exosomes.
Authors
Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name
PLoS One
Publication year
2013
Sample
Thymus
Sample name
Normal-Thymus
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for EGFR
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
SHC1
6464
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
2
STAT5B
6777
Invivo
Homo sapiens
3
CSK
1445
Affinity Capture-MS
Homo sapiens
4
STAT5A
6776
Affinity Capture-Western
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
5
CRK
1398
Affinity Capture-Western
Homo sapiens
Affinity Capture-MS
Homo sapiens
Biochemical Activity
Homo sapiens
6
CAV3
Invivo
Homo sapiens
Invitro
Homo sapiens
7
EPS15
2060
Affinity Capture-Western
Homo sapiens
8
SOCS1
Invivo
Homo sapiens
9
EPS8
2059
Invivo
Homo sapiens
10
GRB10
2887
Invivo
Homo sapiens
Invitro
Homo sapiens
Reconstituted Complex
Homo sapiens
11
PTPN1
5770
Invivo
Homo sapiens
Invivo
Homo sapiens
Invivo
Homo sapiens
Invitro
Homo sapiens
Invitro
Homo sapiens
Invitro
Homo sapiens
12
SNX6
58533
Invivo
Homo sapiens
Invitro
Homo sapiens
13
GRB7
2886
Invivo
Homo sapiens
Invitro
Homo sapiens
14
WAS
7454
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
15
CASP1
Invivo
Homo sapiens
Invitro
Homo sapiens
16
IGF1R
3480
Affinity Capture-Western
Homo sapiens
17
ERBB3
2065
Invivo
Homo sapiens
18
MUC1
4582
Invivo
Homo sapiens
Invivo
Homo sapiens
19
SRC
6714
Affinity Capture-Western
Homo sapiens
Invitro
Homo sapiens
Affinity Capture-Western
Homo sapiens
20
STAT3
6774
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
21
MAPK14
1432
Biochemical Activity
Homo sapiens
22
PLCG1
5335
Invivo
Homo sapiens
23
RUTBC1
Two-hybrid
Homo sapiens
24
PLD2
5338
Affinity Capture-Western
Homo sapiens
25
LRSAM1
90678
Affinity Capture-Western
Homo sapiens
26
SOCS3
9021
Invivo
Homo sapiens
Invitro
Homo sapiens
27
SH3BGRL
6451
Affinity Capture-MS
Homo sapiens
28
NCK1
4690
Reconstituted Complex
Homo sapiens
29
SNX4
8723
Invivo
Homo sapiens
30
CAMLG
819
Affinity Capture-Western
Homo sapiens
31
RIPK1
Invivo
Homo sapiens
32
VAV1
7409
Affinity Capture-Western
Homo sapiens
33
PLSCR1
5359
Co-fractionation
Homo sapiens
Affinity Capture-Western
Homo sapiens
34
PDGFRB
5159
Invivo
Homo sapiens
35
GRB14
Reconstituted Complex
Homo sapiens
Reconstituted Complex
Homo sapiens
36
CBL
867
Affinity Capture-Western
Homo sapiens
37
HTT
3064
Affinity Capture-Western
Homo sapiens
38
EREG
Invivo
Homo sapiens
39
PTK6
Affinity Capture-Western
Homo sapiens
40
CDH1
999
Affinity Capture-Western
Homo sapiens
41
TNC
3371
Invivo
Homo sapiens
Invitro
Homo sapiens
42
PTK2B
2185
Affinity Capture-Western
Homo sapiens
43
SOS1
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
44
MAP4K1
Co-fractionation
Homo sapiens
45
EGF
1950
Reconstituted Complex
Homo sapiens
Reconstituted Complex
Homo sapiens
46
SNX1
6642
Invivo
Homo sapiens
Invivo
Homo sapiens
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
47
DOK2
9046
Reconstituted Complex
Homo sapiens
48
PTPN11
5781
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
49
PTPN6
5777
Invivo
Homo sapiens
Invitro
Homo sapiens
Affinity Capture-Western
Homo sapiens
50
CTNNB1
1499
Reconstituted Complex
Homo sapiens
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
51
FER
Invivo
Homo sapiens
52
PRKAR1A
5573
Affinity Capture-Western
Homo sapiens
53
TJP1
7082
Affinity Capture-Western
Homo sapiens
54
AMH
Invitro
Homo sapiens
55
EGFR
1956
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
56
PTK2
5747
Affinity Capture-Western
Homo sapiens
57
CBLB
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
58
PIK3C2B
5287
Invitro
Homo sapiens
59
GAB1
Invivo
Homo sapiens
60
DCN
1634
Invivo
Homo sapiens
Invitro
Homo sapiens
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
Reconstituted Complex
Homo sapiens
61
PITPNA
5306
Invivo
Homo sapiens
Invitro
Homo sapiens
62
PRKACA
5566
Affinity Capture-Western
Homo sapiens
63
STAT1
6772
Invivo
Homo sapiens
Invitro
Homo sapiens
Affinity Capture-Western
Homo sapiens
64
SOS2
6655
Affinity Capture-Western
Homo sapiens
65
HBEGF
Affinity Capture-Western
Homo sapiens
66
ERBB2
2064
Invivo
Homo sapiens
Invitro
Homo sapiens
67
TGFA
Invitro
Homo sapiens
68
SHC3
Invivo
Homo sapiens
69
VAV2
Affinity Capture-Western
Homo sapiens
Invivo
Homo sapiens
Invitro
Homo sapiens
70
CD82
3732
Invivo
Homo sapiens
Invitro
Homo sapiens
71
CBLC
Affinity Capture-Western
Homo sapiens
Invivo
Homo sapiens
Invitro
Homo sapiens
72
RASA1
5921
Reconstituted Complex
Homo sapiens
73
CDC25A
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
Biochemical Activity
Homo sapiens
Affinity Capture-Western
Homo sapiens
74
MAP3K14
Invivo
Homo sapiens
75
GRB2
2885
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
Invivo
Homo sapiens
Invitro
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
76
JUP
3728
Reconstituted Complex
Homo sapiens
77
INPPL1
3636
Affinity Capture-Western
Homo sapiens
78
VAV3
Affinity Capture-Western
Homo sapiens
79
DUSP3
1845
Biochemical Activity
Homo sapiens
80
ROS1
Affinity Capture-Western
Homo sapiens
81
RGS16
6004
Invivo
Homo sapiens
82
ARF4
378
Two-hybrid
Homo sapiens
Affinity Capture-Western
Homo sapiens
83
NCK2
8440
Invivo
Homo sapiens
Reconstituted Complex
Homo sapiens
84
ESR1
Invitro
Homo sapiens
85
SH2D3A
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
86
NRG1
Invitro
Homo sapiens
87
PRKCA
5578
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
88
Grap2
Affinity Capture-Western
Mus musculus
89
CEBPB
Invivo
Homo sapiens
Invitro
Homo sapiens
90
AREG
374
Reconstituted Complex
Homo sapiens
91
SNX2
6643
Invivo
Homo sapiens
Invitro
Homo sapiens
92
ATP5C1
509
Two-hybrid
Homo sapiens
93
CD44
960
Invivo
Homo sapiens
94
AR
367
Co-localization
Homo sapiens
Co-localization
Homo sapiens
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
95
JAK2
3717
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
96
CAV1
857
Invivo
Homo sapiens
Invitro
Homo sapiens
97
CTNND1
1500
Reconstituted Complex
Homo sapiens
View the network
image/svg+xml
Pathways in which EGFR is involved