Gene description for SLC30A9
Gene name solute carrier family 30 (zinc transporter), member 9
Gene symbol SLC30A9
Other names/aliases C4orf1
GAC63
HUEL
ZNT9
Species Homo sapiens
 Database cross references - SLC30A9
ExoCarta ExoCarta_10463
Vesiclepedia VP_10463
Entrez Gene 10463
HGNC 1329
MIM 604604
UniProt Q6PML9  
 SLC30A9 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for SLC30A9
Molecular Function
    chromatin binding GO:0003682 IEA
    zinc ion transmembrane transporter activity GO:0005385 IDA
    antiporter activity GO:0015297 IEA
    nuclear receptor binding GO:0016922 IEA
    nuclear receptor coactivator activity GO:0030374 IEA
Biological Process
    nucleotide-excision repair GO:0006289 TAS
    zinc ion transport GO:0006829 IBA
    zinc ion transport GO:0006829 IMP
    intracellular zinc ion homeostasis GO:0006882 IBA
    intracellular zinc ion homeostasis GO:0006882 IMP
    regulation of mitochondrion organization GO:0010821 IDA
    positive regulation of transcription by RNA polymerase II GO:0045944 IEA
    zinc ion transmembrane transport GO:0071577 IEA
Subcellular Localization
    nucleus GO:0005634 IDA
    mitochondrion GO:0005739 HTP
    endoplasmic reticulum GO:0005783 IBA
    endoplasmic reticulum GO:0005783 IDA
    cytoskeleton GO:0005856 IDA
    cytoplasmic vesicle GO:0031410 IDA
    mitochondrial membrane GO:0031966 IDA
 Experiment description of studies that identified SLC30A9 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for SLC30A9
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PDHA1 5160
Proximity Label-MS Homo sapiens
2 SLIRP 81892
Proximity Label-MS Homo sapiens
3 NUF2  
Affinity Capture-MS Homo sapiens
4 MTCH1 23787
Proximity Label-MS Homo sapiens
5 TSPAN15 23555
Affinity Capture-MS Homo sapiens
6 LAMP3  
Proximity Label-MS Homo sapiens
7 TRUB2  
Proximity Label-MS Homo sapiens
8 ASGR2  
Affinity Capture-MS Homo sapiens
9 MTG2  
Proximity Label-MS Homo sapiens
10 CHCHD1  
Proximity Label-MS Homo sapiens
11 HSD17B11 51170
Proximity Label-MS Homo sapiens
12 LAMP2 3920
Proximity Label-MS Homo sapiens
13 MAMDC4  
Affinity Capture-MS Homo sapiens
14 DNAJC15  
Proximity Label-MS Homo sapiens
15 MTRF1  
Proximity Label-MS Homo sapiens
16 GFM2 84340
Proximity Label-MS Homo sapiens
17 CCDC90B  
Proximity Label-MS Homo sapiens
18 LRPPRC 10128
Proximity Label-MS Homo sapiens
19 MCU 90550
Proximity Label-MS Homo sapiens
20 PMPCA 23203
Proximity Label-MS Homo sapiens
21 C8orf82  
Proximity Label-MS Homo sapiens
22 COPS5 10987
Affinity Capture-MS Homo sapiens
23 HINT2 84681
Proximity Label-MS Homo sapiens
24 MARCH5  
Proximity Label-MS Homo sapiens
25 MRPS26 64949
Proximity Label-MS Homo sapiens
26 SURF1  
Proximity Label-MS Homo sapiens
27 GJD3  
Proximity Label-MS Homo sapiens
28 C3orf52  
Affinity Capture-MS Homo sapiens
29 SPDEF  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 SLC25A46 91137
Proximity Label-MS Homo sapiens
31 F2RL1  
Affinity Capture-MS Homo sapiens
32 PMPCB 9512
Proximity Label-MS Homo sapiens
33 TACO1  
Proximity Label-MS Homo sapiens
34 MTERF3  
Proximity Label-MS Homo sapiens
35 LMAN1 3998
Proximity Label-MS Homo sapiens
36 MDH2 4191
Proximity Label-MS Homo sapiens
37 VSIG4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 APOO 79135
Proximity Label-MS Homo sapiens
39 CD70 970
Affinity Capture-MS Homo sapiens
40 C6orf203  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
41 COX15 1355
Proximity Label-MS Homo sapiens
42 FASTKD5  
Proximity Label-MS Homo sapiens
43 CD7  
Affinity Capture-MS Homo sapiens
44 COMTD1 118881
Affinity Capture-MS Homo sapiens
45 TUFM 7284
Proximity Label-MS Homo sapiens
46 HSCB 150274
Proximity Label-MS Homo sapiens
47 TBC1D15 64786
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 CCDC109B 55013
Proximity Label-MS Homo sapiens
49 GFM1 85476
Proximity Label-MS Homo sapiens
50 MRPL11 65003
Proximity Label-MS Homo sapiens
51 DNAJC30  
Proximity Label-MS Homo sapiens
52 ELOVL5 60481
Proximity Label-MS Homo sapiens
53 TMEM70  
Proximity Label-MS Homo sapiens
54 COX4I1 1327
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 RAMP2  
Affinity Capture-MS Homo sapiens
56 MRRF  
Proximity Label-MS Homo sapiens
57 RPN2 6185
Proximity Label-MS Homo sapiens
58 AIFM1 9131
Affinity Capture-MS Homo sapiens
59 MRPS12  
Proximity Label-MS Homo sapiens
60 MTIF2 4528
Proximity Label-MS Homo sapiens
61 BTNL9  
Affinity Capture-MS Homo sapiens
62 EGLN3  
Affinity Capture-MS Homo sapiens
63 CLPP 8192
Proximity Label-MS Homo sapiens
64 TNFSF8  
Affinity Capture-MS Homo sapiens
65 MTIF3  
Proximity Label-MS Homo sapiens
66 CHST8 64377
Affinity Capture-MS Homo sapiens
67 ERGIC3 51614
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 BCAP31 10134
Proximity Label-MS Homo sapiens
69 HSD3B7 80270
Proximity Label-MS Homo sapiens
70 RMND1 55005
Proximity Label-MS Homo sapiens
71 FKBP8 23770
Proximity Label-MS Homo sapiens
72 KLRD1  
Affinity Capture-MS Homo sapiens
73 ARF6 382
Proximity Label-MS Homo sapiens
74 AQP3  
Affinity Capture-MS Homo sapiens
75 OCIAD1 54940
Proximity Label-MS Homo sapiens
76 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
77 C12orf65  
Proximity Label-MS Homo sapiens
78 BIRC6 57448
Affinity Capture-MS Homo sapiens
79 HLA-DQA1 3117
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 GPR45  
Affinity Capture-MS Homo sapiens
81 TSFM 10102
Proximity Label-MS Homo sapiens
82 ASPH 444
Affinity Capture-MS Homo sapiens
83 ACAD9 28976
Proximity Label-MS Homo sapiens
84 HSPA9 3313
Proximity Label-MS Homo sapiens
85 AKAP1 8165
Proximity Label-MS Homo sapiens
86 MCUR1 63933
Proximity Label-MS Homo sapiens
87 SLC22A18 5002
Affinity Capture-MS Homo sapiens
88 ACBD5 91452
Proximity Label-MS Homo sapiens
89 LYZL2  
Affinity Capture-MS Homo sapiens
90 DNAJC4  
Proximity Label-MS Homo sapiens
91 DHX15 1665
Co-fractionation Homo sapiens
92 DNAJC28  
Proximity Label-MS Homo sapiens
93 CS 1431
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
94 C17orf80 55028
Proximity Label-MS Homo sapiens
95 PHB2 11331
Proximity Label-MS Homo sapiens
96 VNN2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
97 AUH 549
Proximity Label-MS Homo sapiens
98 DNAJC19 131118
Proximity Label-MS Homo sapiens
99 HLA-DMB 3109
Affinity Capture-MS Homo sapiens
100 LDLRAD1  
Affinity Capture-MS Homo sapiens
101 LONP1 9361
Proximity Label-MS Homo sapiens
102 COX5A 9377
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
103 DNAJA3 9093
Proximity Label-MS Homo sapiens
104 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
105 COX8A  
Proximity Label-MS Homo sapiens
106 CLEC4E  
Affinity Capture-MS Homo sapiens
107 ERGIC1 57222
Proximity Label-MS Homo sapiens
108 C21orf33  
Proximity Label-MS Homo sapiens
109 SSBP1 6742
Proximity Label-MS Homo sapiens
110 SFXN1 94081
Proximity Label-MS Homo sapiens
111 SMPD2 6610
Affinity Capture-MS Homo sapiens
112 PXMP2  
Proximity Label-MS Homo sapiens
113 TBRG4 9238
Proximity Label-MS Homo sapiens
114 AARS2  
Proximity Label-MS Homo sapiens
115 SLC25A51  
Proximity Label-MS Homo sapiens
116 RPUSD3  
Proximity Label-MS Homo sapiens
117 STK11 6794
Negative Genetic Homo sapiens
118 C1QBP 708
Proximity Label-MS Homo sapiens
119 RAB5C 5878
Proximity Label-MS Homo sapiens
120 METTL17  
Proximity Label-MS Homo sapiens
121 RAB2A 5862
Proximity Label-MS Homo sapiens
122 HLA-C 3107
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which SLC30A9 is involved
No pathways found





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