Gene description for REL
Gene name	v-rel avian reticuloendotheliosis viral oncogene homolog
Gene symbol	REL
Other names/aliases	C-Rel
Species	Homo sapiens
Database cross references - REL
ExoCarta	ExoCarta_5966
Vesiclepedia	VP_5966
Entrez Gene	5966
HGNC	9954
MIM	164910
UniProt	Q04864
REL identified in sEVs derived from the following tissue/cell type
Neuroblastoma cells	25944692

Gene ontology annotations for REL

Molecular Function     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IDA     DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 IBA     DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 ISA     DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 IDA     DNA-binding transcription factor activity GO:0003700 NAS     protein binding GO:0005515 IPI Biological Process     inflammatory response GO:0006954 IBA     canonical NF-kappaB signal transduction GO:0007249 IBA     negative regulation of gene expression GO:0010629 IDA     negative regulation of interferon-beta production GO:0032688 IDA     response to cytokine GO:0034097 IBA     non-canonical NF-kappaB signal transduction GO:0038061 IBA     positive regulation of canonical NF-kappaB signal transduction GO:0043123 IEP     innate immune response GO:0045087 IBA     positive regulation of transcription by RNA polymerase II GO:0045944 IBA     positive regulation of transcription by RNA polymerase II GO:0045944 IDA     positive regulation of transcription by RNA polymerase II GO:0045944 NAS Subcellular Localization     chromatin GO:0000785 ISA     nucleus GO:0005634 IBA     nucleus GO:0005634 IMP     nucleoplasm GO:0005654 TAS     cytoplasm GO:0005737 IBA     cytosol GO:0005829 TAS     NF-kappaB complex GO:0071159 NAS