Gene description for ASPH
Gene name aspartate beta-hydroxylase
Gene symbol ASPH
Other names/aliases AAH
BAH
CASQ2BP1
FDLAB
HAAH
JCTN
junctin
Species Homo sapiens
 Database cross references - ASPH
ExoCarta ExoCarta_444
Vesiclepedia VP_444
Entrez Gene 444
HGNC 757
MIM 600582
UniProt Q12797  
 ASPH identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Prostate cancer cells 25844599    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
T lymphocytes 34108659    
 Gene ontology annotations for ASPH
Molecular Function
    structural molecule activity GO:0005198 TAS
    calcium ion binding GO:0005509 IDA
    calcium ion binding GO:0005509 NAS
    protein binding GO:0005515 IPI
    structural constituent of muscle GO:0008307 TAS
    electron transfer activity GO:0009055 TAS
    transmembrane transporter binding GO:0044325 TAS
    peptidyl-aspartic acid 3-dioxygenase activity GO:0062101 IBA
Biological Process
    detection of calcium ion GO:0005513 TAS
    muscle contraction GO:0006936 TAS
    pattern specification process GO:0007389 IEA
    cell population proliferation GO:0008283 IEA
    negative regulation of cell population proliferation GO:0008285 IEA
    positive regulation of calcium ion transport into cytosol GO:0010524 IDA
    regulation of cell communication by electrical coupling GO:0010649 TAS
    regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 TAS
    regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion GO:0010881 TAS
    regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity GO:0031585 IDA
    regulation of protein stability GO:0031647 IEA
    activation of store-operated calcium channel activity GO:0032237 IDA
    response to ATP GO:0033198 IDA
    limb morphogenesis GO:0035108 IEA
    positive regulation of proteolysis GO:0045862 IDA
    positive regulation of DNA-templated transcription GO:0045893 IMP
    regulation of cytosolic calcium ion concentration GO:0051480 IBA
    calcium ion homeostasis GO:0055074 IDA
    roof of mouth development GO:0060021 IEA
    regulation of ryanodine-sensitive calcium-release channel activity GO:0060314 TAS
    positive regulation of ryanodine-sensitive calcium-release channel activity GO:0060316 TAS
    face morphogenesis GO:0060325 IEA
    calcium ion transmembrane transport GO:0070588 IDA
    cellular response to calcium ion GO:0071277 IDA
    positive regulation of intracellular protein transport GO:0090316 IDA
    activation of cysteine-type endopeptidase activity GO:0097202 IDA
    regulation of protein depolymerization GO:1901879 IEA
Subcellular Localization
    endoplasmic reticulum GO:0005783 IBA
    endoplasmic reticulum GO:0005783 IDA
    endoplasmic reticulum membrane GO:0005789 IDA
    endoplasmic reticulum membrane GO:0005789 NAS
    endoplasmic reticulum membrane GO:0005789 TAS
    plasma membrane GO:0005886 IDA
    junctional sarcoplasmic reticulum membrane GO:0014701 TAS
    cortical endoplasmic reticulum GO:0032541 IDA
    sarcoplasmic reticulum membrane GO:0033017 IEA
    sarcoplasmic reticulum membrane GO:0033017 TAS
    sarcoplasmic reticulum lumen GO:0033018 TAS
    calcium channel complex GO:0034704 TAS
 Experiment description of studies that identified ASPH in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
15
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
16
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
17
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
18
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
20
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
26
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
27
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
31
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
32
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
33
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for ASPH
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 TMCO1 54499
Affinity Capture-MS Homo sapiens
3 SLC37A4 2542
Affinity Capture-MS Homo sapiens
4 SLC25A40  
Affinity Capture-MS Homo sapiens
5 CMTM6 54918
Affinity Capture-MS Homo sapiens
6 ZG16  
Two-hybrid Homo sapiens
7 POR 5447
Co-fractionation Homo sapiens
8 PRB4  
Two-hybrid Homo sapiens
9 GPR119  
Two-hybrid Homo sapiens
10 VTI1B 10490
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 HEATR6  
Affinity Capture-MS Homo sapiens
12 NDUFS1 4719
Co-fractionation Homo sapiens
13 HLA-E 3133
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 NAPA 8775
Affinity Capture-MS Homo sapiens
15 CALU 813
Proximity Label-MS Homo sapiens
16 TPP1 1200
Co-fractionation Homo sapiens
17 TARDBP 23435
Affinity Capture-MS Homo sapiens
18 FGFBP1 9982
Two-hybrid Homo sapiens
19 VAMP7 6845
Affinity Capture-MS Homo sapiens
20 BGLAP  
Two-hybrid Homo sapiens
21 SRPR 6734
Affinity Capture-MS Homo sapiens
22 PLEKHF2 79666
Two-hybrid Homo sapiens
23 C9orf78 51759
Affinity Capture-MS Homo sapiens
24 DHRSX 207063
Two-hybrid Homo sapiens
25 NDUFS7 374291
Co-fractionation Homo sapiens
26 LRRC59 55379
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
27 SYVN1 84447
Affinity Capture-MS Homo sapiens
28 STX4 6810
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 SOX2  
Affinity Capture-MS Homo sapiens
30 KCNIP3  
Two-hybrid Homo sapiens
31 POTEF 728378
Affinity Capture-MS Homo sapiens
32 LRPPRC 10128
Co-fractionation Homo sapiens
33 KIAA1429 25962
Affinity Capture-MS Homo sapiens
34 UGT2B11  
Two-hybrid Homo sapiens
35 RNPS1 10921
Affinity Capture-MS Homo sapiens
36 NDUFS3 4722
Co-fractionation Homo sapiens
37 DYRK1A 1859
Affinity Capture-MS Homo sapiens
38 KIF23 9493
Affinity Capture-MS Homo sapiens
39 TMEM167B  
Two-hybrid Homo sapiens
40 TIMMDC1  
Affinity Capture-MS Homo sapiens
41 RCN2 5955
Co-fractionation Homo sapiens
42 FBXW7  
Affinity Capture-MS Homo sapiens
43 TM9SF4 9777
Affinity Capture-MS Homo sapiens
44 STX8 9482
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 CLEC2B  
Affinity Capture-MS Homo sapiens
46 STX7 8417
Affinity Capture-MS Homo sapiens
47 SIGMAR1 10280
Affinity Capture-MS Homo sapiens
48 OBSL1 23363
Affinity Capture-MS Homo sapiens
49 TMEM55B 90809
Affinity Capture-MS Homo sapiens
50 SF3A2 8175
Two-hybrid Homo sapiens
51 STEAP3 55240
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 PTH  
Two-hybrid Homo sapiens
53 EPHA1 2041
Affinity Capture-MS Homo sapiens
54 MRS2  
Affinity Capture-MS Homo sapiens
55 EXD2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 STX6 10228
Affinity Capture-MS Homo sapiens
57 LACTB 114294
Co-fractionation Homo sapiens
58 CCDC47 57003
Affinity Capture-MS Homo sapiens
59 SLC51B  
Two-hybrid Homo sapiens
60 NDUFV1 4723
Co-fractionation Homo sapiens
61 GUCA2A  
Two-hybrid Homo sapiens
62 F2RL1  
Affinity Capture-MS Homo sapiens
63 WFDC5  
Two-hybrid Homo sapiens
64 CALR 811
Co-fractionation Homo sapiens
65 CST1  
Two-hybrid Homo sapiens
66 TMEM259 91304
Affinity Capture-MS Homo sapiens
67 GPX8 493869
Two-hybrid Homo sapiens
68 HRASLS2  
Two-hybrid Homo sapiens
69 STX10 8677
Affinity Capture-MS Homo sapiens
70 HK1 3098
Co-fractionation Homo sapiens
71 FAM20C 56975
Affinity Capture-MS Homo sapiens
72 STX12 23673
Affinity Capture-MS Homo sapiens
73 ESR1  
Affinity Capture-MS Homo sapiens
74 NOTCH2 4853
Affinity Capture-MS Homo sapiens
75 STX18 53407
Affinity Capture-MS Homo sapiens
76 PRH1  
Two-hybrid Homo sapiens
77 TAZ  
Affinity Capture-MS Homo sapiens
78 E2F4  
Affinity Capture-MS Homo sapiens
79 ENPP6 133121
Two-hybrid Homo sapiens
80 RHBDF2 79651
Affinity Capture-MS Homo sapiens
81 SFXN2  
Affinity Capture-MS Homo sapiens
82 PRAP1  
Two-hybrid Homo sapiens
83 DDOST 1650
Affinity Capture-MS Homo sapiens
84 SCGB1C2  
Two-hybrid Homo sapiens
85 NOMO1 23420
Affinity Capture-MS Homo sapiens
86 P4HA1 5033
Co-fractionation Homo sapiens
87 SEC61A2 55176
Affinity Capture-MS Homo sapiens
88 LTBP2 4053
Affinity Capture-MS Homo sapiens
89 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
90 RELL2  
Two-hybrid Homo sapiens
91 BNIP1 662
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
92 VPS45 11311
Affinity Capture-MS Homo sapiens
93 SFXN3 81855
Affinity Capture-MS Homo sapiens
94 NDUFA8 4702
Co-fractionation Homo sapiens
95 PRB2  
Two-hybrid Homo sapiens
96 TUFM 7284
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
97 ASNA1 439
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
98 FAM162A 26355
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
99 PGRMC2 10424
Cross-Linking-MS (XL-MS) Homo sapiens
100 SMIM11  
Two-hybrid Homo sapiens
101 NDUFS8 4728
Co-fractionation Homo sapiens
102 IDS  
Affinity Capture-MS Homo sapiens
103 SMIM19  
Two-hybrid Homo sapiens
104 WDYHV1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
105 OGT 8473
Reconstituted Complex Homo sapiens
106 LEMD2 221496
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
107 FAM19A5 25817
Affinity Capture-MS Homo sapiens
108 CCDC109B 55013
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
109 BCHE 590
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
110 EEF2 1938
Co-fractionation Homo sapiens
111 MIA3 375056
Affinity Capture-MS Homo sapiens
112 NOS2  
Affinity Capture-MS Homo sapiens
113 AGR2 10551
Two-hybrid Homo sapiens
114 CYC1 1537
Co-fractionation Homo sapiens
115 UQCRC1 7384
Co-fractionation Homo sapiens
116 SLC25A19  
Affinity Capture-MS Homo sapiens
117 TMEM192 201931
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
118 FBLN5 10516
Affinity Capture-MS Homo sapiens
119 HECTD1 25831
Affinity Capture-MS Homo sapiens
120 OST4  
Affinity Capture-MS Homo sapiens
121 UQCRH 7388
Co-fractionation Homo sapiens
122 SLC35F2 54733
Affinity Capture-MS Homo sapiens
123 MPDU1 9526
Affinity Capture-MS Homo sapiens
124 SEC61B 10952
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
125 ATP5B 506
Co-fractionation Homo sapiens
126 CD93  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
127 VCP 7415
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
128 NDUFAF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
129 RNASEH1 246243
Two-hybrid Homo sapiens
130 GAST  
Two-hybrid Homo sapiens
131 ANLN 54443
Affinity Capture-MS Homo sapiens
132 PTN  
Two-hybrid Homo sapiens
133 CDS2 8760
Affinity Capture-MS Homo sapiens
134 HSPA5 3309
Proximity Label-MS Homo sapiens
135 C4orf32  
Affinity Capture-MS Homo sapiens
136 HADHB 3032
Co-fractionation Homo sapiens
137 HADHA 3030
Co-fractionation Homo sapiens
138 VAPB 9217
Affinity Capture-MS Homo sapiens
139 LOC102723553  
Two-hybrid Homo sapiens
140 CANX 821
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
141 ATL3 25923
Co-fractionation Homo sapiens
142 BCKDHB 594
Co-fractionation Homo sapiens
143 EMC8 10328
Co-fractionation Homo sapiens
144 CALR3  
Proximity Label-MS Homo sapiens
145 NDUFA9 4704
Co-fractionation Homo sapiens
146 RC3H2  
Affinity Capture-MS Homo sapiens
147 CXorf66  
Two-hybrid Homo sapiens
148 LETM1 3954
Co-fractionation Homo sapiens
149 UQCRC2 7385
Co-fractionation Homo sapiens
150 HMOX2 3163
Co-fractionation Homo sapiens
151 IQCB1  
Affinity Capture-MS Homo sapiens
152 SOD3 6649
Two-hybrid Homo sapiens
153 KCNIP1  
Two-hybrid Homo sapiens
154 VAMP3 9341
Affinity Capture-MS Homo sapiens
155 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
156 TMEM160 54958
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
157 HTR2C  
Affinity Capture-MS Homo sapiens
158 FTH1 2495
Co-fractionation Homo sapiens
159 INSL5  
Two-hybrid Homo sapiens
160 SDC2 6383
Two-hybrid Homo sapiens
161 OCIAD1 54940
Two-hybrid Homo sapiens
162 SGTB  
Two-hybrid Homo sapiens
163 SMDT1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
164 NELL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
165 FAM134C 162427
Affinity Capture-MS Homo sapiens
166 RFT1 91869
Affinity Capture-MS Homo sapiens
167 MYC  
Affinity Capture-MS Homo sapiens
168 RPA3 6119
Proximity Label-MS Homo sapiens
169 EMC2 9694
Co-fractionation Homo sapiens
170 ATP6V1A 523
Co-fractionation Homo sapiens
171 CHRM5  
Two-hybrid Homo sapiens
172 KCNN4 3783
Affinity Capture-MS Homo sapiens
173 ACAD9 28976
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
174 SPINK1 6690
Two-hybrid Homo sapiens
175 DDRGK1 65992
Affinity Capture-MS Homo sapiens
176 COX2 4513
Co-fractionation Homo sapiens
177 RNF185  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
178 NDUFV2 4729
Co-fractionation Homo sapiens
179 PRB1  
Two-hybrid Homo sapiens
180 RPS16 6217
Affinity Capture-MS Homo sapiens
181 APP 351
Reconstituted Complex Homo sapiens
182 TMX2 51075
Two-hybrid Homo sapiens
183 GOLM1 51280
Two-hybrid Homo sapiens
184 LYZL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
185 PDGFA 5154
Two-hybrid Homo sapiens
186 FDCSP  
Two-hybrid Homo sapiens
187 PIGU 128869
Affinity Capture-MS Homo sapiens
188 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
189 TMED10 10972
Affinity Capture-MS Homo sapiens
190 ABCB6 10058
Affinity Capture-MS Homo sapiens
191 SERPINA12  
Affinity Capture-MS Homo sapiens
192 VTI1A 143187
Affinity Capture-MS Homo sapiens
193 FBXL6  
Affinity Capture-MS Homo sapiens
194 TP53 7157
Affinity Capture-MS Homo sapiens
195 OLFM1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
196 TXNDC15  
Two-hybrid Homo sapiens
197 PTRF 284119
Co-fractionation Homo sapiens
198 ATP1A3 478
Affinity Capture-MS Homo sapiens
199 HLA-DRA 3122
Affinity Capture-MS Homo sapiens
200 PDIA4 9601
Proximity Label-MS Homo sapiens
201 LONP1 9361
Co-fractionation Homo sapiens
202 LTA  
Two-hybrid Homo sapiens
203 BCKDHA 593
Co-fractionation Homo sapiens
204 VAPA 9218
Affinity Capture-MS Homo sapiens
205 PDHA1 5160
Co-fractionation Homo sapiens
206 CDSN 1041
Two-hybrid Homo sapiens
207 SLC7A6OS  
Affinity Capture-MS Homo sapiens
208 RPS15 6209
Cross-Linking-MS (XL-MS) Homo sapiens
209 Htt  
Affinity Capture-MS Mus musculus
210 PDHB 5162
Co-fractionation Homo sapiens
211 COX8A  
Co-fractionation Homo sapiens
212 IL21  
Two-hybrid Homo sapiens
213 ATP2A2 488
Co-fractionation Homo sapiens
214 ND4 4538
Affinity Capture-MS Homo sapiens
215 BCAP29 55973
Affinity Capture-MS Homo sapiens
216 SQSTM1 8878
Affinity Capture-MS Homo sapiens
217 DCD 117159
Two-hybrid Homo sapiens
218 UFL1 23376
Affinity Capture-MS Homo sapiens
219 NNT 23530
Co-fractionation Homo sapiens
220 TNFRSF10B 8795
Two-hybrid Homo sapiens
221 STXBP3 6814
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
222 FBLN7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
223 LRPAP1 4043
Two-hybrid Homo sapiens
224 SLC25A4 291
Affinity Capture-MS Homo sapiens
225 DEFB1  
Two-hybrid Homo sapiens
226 TRIM31  
Affinity Capture-MS Homo sapiens
227 MGME1  
Affinity Capture-MS Homo sapiens
228 SLC30A9 10463
Affinity Capture-MS Homo sapiens
229 CIT 11113
Affinity Capture-MS Homo sapiens
230 MCU 90550
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
231 KCNIP4 80333
Two-hybrid Homo sapiens
232 EI24  
Affinity Capture-MS Homo sapiens
233 COX7C 1350
Co-fractionation Homo sapiens
234 LCN2 3934
Two-hybrid Homo sapiens
235 RC3H1 149041
Affinity Capture-MS Homo sapiens
236 GPX7 2882
Two-hybrid Homo sapiens
237 SLC1A1 6505
Affinity Capture-MS Homo sapiens
238 PTCH1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
239 STX17 55014
Affinity Capture-MS Homo sapiens
240 PVRL3 25945
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
241 PIGS 94005
Affinity Capture-MS Homo sapiens
242 KIAA1644  
Two-hybrid Homo sapiens
243 WFDC12  
Two-hybrid Homo sapiens
244 ECSIT 51295
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
245 PCSK4  
Two-hybrid Homo sapiens
246 GTF2E2  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here