Gene description for RPL23
Gene name ribosomal protein L23
Gene symbol RPL23
Other names/aliases L23
rpL17
Species Homo sapiens
 Database cross references - RPL23
ExoCarta ExoCarta_9349
Vesiclepedia VP_9349
Entrez Gene 9349
HGNC 10316
MIM 603662
UniProt P62829  
 RPL23 identified in sEVs derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
B cells 20458337    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 36706192    
Embryonic kidney cells 36706192    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells Unpublished / Not applicable
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for RPL23
Molecular Function
    transcription coactivator binding GO:0001223 IPI
    RNA binding GO:0003723 HDA
    structural constituent of ribosome GO:0003735 IBA
    structural constituent of ribosome GO:0003735 IDA
    structural constituent of ribosome GO:0003735 NAS
    protein binding GO:0005515 IPI
    ubiquitin protein ligase binding GO:0031625 IPI
    large ribosomal subunit rRNA binding GO:0070180 IBA
    ubiquitin ligase inhibitor activity GO:1990948 IDA
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IMP
    cytoplasmic translation GO:0002181 IC
    cytoplasmic translation GO:0002181 NAS
    translation GO:0006412 NAS
    ribosomal protein import into nucleus GO:0006610 NAS
    positive regulation of cell population proliferation GO:0008284 IMP
    positive regulation of gene expression GO:0010628 IMP
    protein-DNA complex disassembly GO:0032986 IDA
    protein stabilization GO:0050821 IMP
    G1 to G0 transition GO:0070314 IMP
    cellular response to actinomycin D GO:0072717 IMP
    positive regulation of signal transduction by p53 class mediator GO:1901798 IMP
    regulation of G1 to G0 transition GO:1903450 IMP
    negative regulation of ubiquitin protein ligase activity GO:1904667 IDA
    negative regulation of ubiquitin-dependent protein catabolic process GO:2000059 IDA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    nucleolus GO:0005730 IDA
    cytoplasm GO:0005737 IDA
    cytoplasm GO:0005737 NAS
    cytosol GO:0005829 TAS
    ribosome GO:0005840 NAS
    focal adhesion GO:0005925 HDA
    membrane GO:0016020 HDA
    cytosolic large ribosomal subunit GO:0022625 HDA
    cytosolic large ribosomal subunit GO:0022625 IBA
    cytosolic large ribosomal subunit GO:0022625 IDA
    cytosolic large ribosomal subunit GO:0022625 IPI
    cytosolic ribosome GO:0022626 IDA
    protein-containing complex GO:0032991 IDA
    protein-containing complex GO:0032991 IMP
    synapse GO:0045202 IEA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified RPL23 in sEVs
1
Experiment ID 79
MISEV standards
Biophysical techniques
CD81|MHCII
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 80
MISEV standards
Biophysical techniques
CD81|MHCII
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 81
MISEV standards
Biophysical techniques
CD81|MHCII
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
4
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 412
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
9
Experiment ID 414
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 426
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 427
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 497
MISEV standards
Biophysical techniques
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
13
Experiment ID 498
MISEV standards
EM
Biophysical techniques
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
14
Experiment ID 1203
MISEV standards
EM
Biophysical techniques
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
15
Experiment ID 407
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 419
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 419
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 420
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 420
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
20
Experiment ID 1275
MISEV standards
Biophysical techniques
CD9|TSG101|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 1280
MISEV standards
Biophysical techniques
TSG101|CD9|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T - Fraction 5
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density 1.151 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 405
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 363
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 364
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
25
Experiment ID 365
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
26
Experiment ID 234
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
27
Experiment ID 235
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
28
Experiment ID 236
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
29
Experiment ID 237
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
30
Experiment ID 417
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 411
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 126
MISEV standards
Biophysical techniques
GAPDH
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
33
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
34
Experiment ID 418
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 418
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 224
MISEV standards
EM|AFM
Biophysical techniques
Alix|TSG101|CD63|CD81
Enriched markers
GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
37
Experiment ID 413
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
38
Experiment ID 406
MISEV standards
EM
Biophysical techniques
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
39
Experiment ID 415
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
40
Experiment ID 434
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
41
Experiment ID 435
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
42
Experiment ID 408
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
43
Experiment ID 409
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
44
Experiment ID 416
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
45
Experiment ID 410
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
46
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RPL23
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CCL3  
Affinity Capture-MS Homo sapiens
2 ISG15 9636
Reconstituted Complex Homo sapiens
3 PCDHGA6 56109
Affinity Capture-MS Homo sapiens
4 UBL4A 8266
Affinity Capture-MS Homo sapiens
5 PAEP  
Affinity Capture-MS Homo sapiens
6 PCDHGB5 56101
Affinity Capture-MS Homo sapiens
7 RIN3  
Affinity Capture-MS Homo sapiens
8 CDH5  
Affinity Capture-MS Homo sapiens
9 CRK 1398
Affinity Capture-MS Homo sapiens
10 PCDHGB4 8641
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 EBNA-LP  
Affinity Capture-MS
12 KIF20A 10112
Affinity Capture-MS Homo sapiens
13 CSNK2A1 1457
Affinity Capture-MS Homo sapiens
14 NHP2L1 4809
Co-fractionation Homo sapiens
15 EFNA3  
Affinity Capture-MS Homo sapiens
16 FAT3 120114
Affinity Capture-MS Homo sapiens
17 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
18 DBH 1621
Affinity Capture-MS Homo sapiens
19 KIF23 9493
Affinity Capture-MS Homo sapiens
20 UBE2O 63893
Affinity Capture-MS Homo sapiens
21 CDH16  
Affinity Capture-MS Homo sapiens
22 FBL 2091
Co-fractionation Homo sapiens
23 ST14 6768
Affinity Capture-MS Homo sapiens
24 RPS9 6203
Co-fractionation Homo sapiens
25 C3orf52  
Affinity Capture-MS Homo sapiens
26 MECP2 4204
Affinity Capture-MS Homo sapiens
27 BTNL2  
Affinity Capture-MS Homo sapiens
28 RPS11 6205
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
29 RPL19 6143
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
30 KIF14 9928
Affinity Capture-MS Homo sapiens
31 NOTCH2 4853
Affinity Capture-MS Homo sapiens
32 EMC9  
Affinity Capture-MS Homo sapiens
33 BAG5 9529
Affinity Capture-MS Homo sapiens
34 AURKA 6790
Affinity Capture-MS Homo sapiens
35 LRRK2 120892
Affinity Capture-MS Homo sapiens
36 USP14 9097
Co-fractionation Homo sapiens
37 CLU 1191
Two-hybrid Homo sapiens
38 PSME1 5720
Affinity Capture-MS Homo sapiens
39 MCAM 4162
Proximity Label-MS Homo sapiens
40 TUFM 7284
Co-fractionation Homo sapiens
41 RPL18A 6142
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
42 ESRRB  
Affinity Capture-MS Homo sapiens
43 Srp72  
Affinity Capture-MS Mus musculus
44 YAP1 10413
Affinity Capture-MS Homo sapiens
45 TRIM21 6737
Affinity Capture-MS Homo sapiens
46 RPL31 6160
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
47 MEOX2  
Two-hybrid Homo sapiens
48 HECTD1 25831
Affinity Capture-MS Homo sapiens
49 CUL2 8453
Affinity Capture-MS Homo sapiens
50 ACTC1 70
Affinity Capture-MS Homo sapiens
51 SEC61B 10952
Affinity Capture-MS Homo sapiens
52 SLC25A5 292
Co-fractionation Homo sapiens
53 ANLN 54443
Affinity Capture-MS Homo sapiens
54 CSNK1G3 1456
Affinity Capture-MS Homo sapiens
55 HSPA5 3309
Affinity Capture-MS Homo sapiens
56 Ddx39 68278
Two-hybrid Mus musculus
57 AHSA1 10598
Affinity Capture-MS Homo sapiens
58 ITGB8 3696
Affinity Capture-MS Homo sapiens
59 ASS1 445
Co-fractionation Homo sapiens
60 FAM187B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
61 FN1 2335
Affinity Capture-MS Homo sapiens
62 CDC42 998
Two-hybrid Homo sapiens
63 PCBP1 5093
Affinity Capture-MS Homo sapiens
64 RPA3 6119
Proximity Label-MS Homo sapiens
65 MAPKAP1 79109
Affinity Capture-Western Homo sapiens
66 RPL35A 6165
Co-fractionation Homo sapiens
67 BRD4 23476
Affinity Capture-MS Homo sapiens
68 DCC  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
69 PCDHA12  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 DNASE1L1 1774
Affinity Capture-MS Homo sapiens
71 Rpl35 66489
Affinity Capture-MS Mus musculus
72 NFATC2  
Affinity Capture-MS Homo sapiens
73 GNL3 26354
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
74 DDX55  
Co-fractionation Homo sapiens
75 RPS16 6217
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
76 CDH13 1012
Affinity Capture-MS Homo sapiens
77 RELA 5970
Two-hybrid Homo sapiens
78 RPS27A 6233
Co-fractionation Homo sapiens
79 WDR77 79084
Affinity Capture-MS Homo sapiens
80 RRS1 23212
Co-fractionation Homo sapiens
81 TUBGCP3 10426
Affinity Capture-MS Homo sapiens
82 APRT 353
Co-fractionation Homo sapiens
83 FKBP9 11328
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 CAPZB 832
Affinity Capture-MS Homo sapiens
85 G3BP2 9908
Affinity Capture-MS Homo sapiens
86 SPOCK2  
Affinity Capture-MS Homo sapiens
87 RPS24 6229
Co-fractionation Homo sapiens
88 NCL 4691
Affinity Capture-MS Homo sapiens
89 ATG4B 23192
Affinity Capture-MS Homo sapiens
90 ACO2 50
Affinity Capture-MS Homo sapiens
91 RPL23A 6147
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
92 MATN2 4147
Affinity Capture-MS Homo sapiens
93 ASB14  
Affinity Capture-MS Homo sapiens
94 SNRPA 6626
Two-hybrid Homo sapiens
95 CHMP4C 92421
Affinity Capture-MS Homo sapiens
96 SPRTN  
Affinity Capture-MS Homo sapiens
97 FSTL4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
98 RPS17 6218
Co-fractionation Homo sapiens
99 TARDBP 23435
Affinity Capture-MS Homo sapiens
100 BTF3 689
Affinity Capture-MS Homo sapiens
101 NOP56 10528
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
102 DYNC1I1  
Affinity Capture-MS Homo sapiens
103 CBWD2  
Affinity Capture-MS Homo sapiens
104 RPL14 9045
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
105 OIT3 170392
Affinity Capture-MS Homo sapiens
106 CAND1 55832
Affinity Capture-MS Homo sapiens
107 EVL 51466
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
108 PCDHA10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
109 RPS3 6188
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
110 MUC20  
Affinity Capture-MS Homo sapiens
111 LGALS3BP 3959
Affinity Capture-MS Homo sapiens
112 LRP1 4035
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
113 Spire2  
Affinity Capture-MS Mus musculus
114 RNPS1 10921
Co-fractionation Homo sapiens
115 B3GNT2 10678
Affinity Capture-MS Homo sapiens
116 COPS6 10980
Affinity Capture-MS Homo sapiens
117 PRC1 9055
Affinity Capture-MS Homo sapiens
118 NPM1 4869
Affinity Capture-MS Homo sapiens
119 MAD2L2 10459
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
120 VCAM1 7412
Affinity Capture-MS Homo sapiens
121 CUL1 8454
Affinity Capture-MS Homo sapiens
122 NACA2 342538
Co-fractionation Homo sapiens
123 RPL10L 140801
Co-fractionation Homo sapiens
124 PES1 23481
Co-fractionation Homo sapiens
125 SMEK2  
Co-fractionation Homo sapiens
126 ACTA2 59
Affinity Capture-MS Homo sapiens
127 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
128 PCDHB6  
Affinity Capture-MS Homo sapiens
129 RPL4 6124
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
130 MRPS11  
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
131 VRK1 7443
Affinity Capture-MS Homo sapiens
132 PCDHGC4  
Affinity Capture-MS Homo sapiens
133 C1orf54  
Affinity Capture-MS Homo sapiens
134 RLIM 51132
Affinity Capture-MS Homo sapiens
135 THBS3 7059
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
136 Bag2  
Affinity Capture-MS Mus musculus
137 RPLP0 6175
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
138 RPLP0P6 220717
Co-fractionation Homo sapiens
139 DDX27 55661
Co-fractionation Homo sapiens
140 Ksr1  
Affinity Capture-MS Mus musculus
141 PCDHA11  
Affinity Capture-MS Homo sapiens
142 RAD21 5885
Affinity Capture-Western Homo sapiens
143 LOC101929876 101929876
Co-fractionation Homo sapiens
144 PCDHA8  
Affinity Capture-MS Homo sapiens
145 RPL32 6161
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
146 COLEC11 78989
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
147 TUBB 203068
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
148 PCDH20  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
149 RPS2 6187
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
150 EMC8 10328
Affinity Capture-MS Homo sapiens
151 EIF6 3692
Co-fractionation Homo sapiens
152 RC3H2  
Affinity Capture-MS Homo sapiens
153 IKZF3  
Affinity Capture-MS Homo sapiens
154 TUBB4B 10383
Affinity Capture-MS Homo sapiens
155 PDIA3 2923
Co-fractionation Homo sapiens
156 RICTOR 253260
Affinity Capture-Western Homo sapiens
157 DAPP1 27071
Two-hybrid Homo sapiens
158 EGFR 1956
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
159 IKZF1  
Affinity Capture-MS Homo sapiens
160 RPS27 6232
Co-fractionation Homo sapiens
161 ARIH2 10425
Affinity Capture-MS Homo sapiens
162 CEP250 11190
Affinity Capture-MS Homo sapiens
163 DNASE1L2  
Affinity Capture-MS Homo sapiens
164 MYC  
Affinity Capture-MS Homo sapiens
165 BAG1 573
Affinity Capture-MS Homo sapiens
166 TMOD2 29767
Affinity Capture-MS Homo sapiens
167 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
168 CUL7 9820
Affinity Capture-MS Homo sapiens
169 VWA8 23078
Proximity Label-MS Homo sapiens
170 RPS18 6222
Co-fractionation Homo sapiens
171 CBWD1 55871
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
172 HUWE1 10075
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
173 PCDHB5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
174 RPL13 6137
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
175 SPOP  
Affinity Capture-MS Homo sapiens
176 ILF3 3609
Co-fractionation Homo sapiens
177 TP53 7157
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
178 FOLR1 2348
Affinity Capture-MS Homo sapiens
179 RPS12 6206
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
180 RPS4X 6191
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
181 CAPRIN1 4076
Affinity Capture-MS Homo sapiens
182 CDK2 1017
Affinity Capture-MS Homo sapiens
183 LSS 4047
Affinity Capture-MS Homo sapiens
184 KLHL7  
Affinity Capture-MS Homo sapiens
185 RPS5 6193
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
186 NIFK 84365
Co-fractionation Homo sapiens
187 AARSD1 80755
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
188 RPS26 6231
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
189 TMEM25  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
190 RPL7A 6130
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
191 SSSCA1 10534
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
192 BCCIP 56647
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
193 PCDHB16  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
194 KRAS 3845
Negative Genetic Homo sapiens
195 LURAP1  
Affinity Capture-MS Homo sapiens
196 HFE  
Affinity Capture-MS Homo sapiens
197 UBE2H 7328
Affinity Capture-MS Homo sapiens
198 RPL26L1 51121
Co-fractionation Homo sapiens
199 PCDHGA5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
200 RPS19 6223
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
201 UQCRB 7381
Co-fractionation Homo sapiens
202 ATG13 9776
Affinity Capture-MS Homo sapiens
203 DIMT1 27292
Affinity Capture-MS Homo sapiens
204 RPL10A 4736
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
205 EMILIN1 11117
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
206 MCM2 4171
Affinity Capture-MS Homo sapiens
207 DDRGK1 65992
Affinity Capture-MS Homo sapiens
208 ITGA4 3676
Affinity Capture-MS Homo sapiens
209 Pef1  
Two-hybrid Mus musculus
210 RPL29 6159
Co-fractionation Homo sapiens
211 DDX18 8886
Co-fractionation Homo sapiens
212 TFCP2 7024
Affinity Capture-MS Homo sapiens
213 CYLD  
Affinity Capture-MS Homo sapiens
214 RBM8A 9939
Affinity Capture-MS Homo sapiens
215 BRIX1 55299
Co-fractionation Homo sapiens
216 RPL27 6155
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
217 DLD 1738
Co-fractionation Homo sapiens
218 RPL9 6133
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
219 RPL26 6154
Co-fractionation Homo sapiens
220 ANTXR1 84168
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
221 PARK2  
Affinity Capture-MS Homo sapiens
222 RPS10 6204
Co-fractionation Homo sapiens
223 FAT4 79633
Affinity Capture-MS Homo sapiens
224 NOP2 4839
Co-fractionation Homo sapiens
225 EPS8L2 64787
Two-hybrid Homo sapiens
226 RPL5 6125
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
227 MSMB  
Affinity Capture-MS Homo sapiens
228 CHMP4B 128866
Affinity Capture-MS Homo sapiens
229 MRPS5 64969
Co-fractionation Homo sapiens
230 CRP  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
231 CLSTN2 64084
Affinity Capture-MS Homo sapiens
232 RPL36 25873
Co-fractionation Homo sapiens
233 CDHR4  
Affinity Capture-MS Homo sapiens
234 S100B 6285
Affinity Capture-MS Homo sapiens
235 RPLP1 6176
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
236 ENY2 56943
Affinity Capture-MS Homo sapiens
237 C1QTNF7  
Affinity Capture-MS Homo sapiens
238 PCDH12 51294
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
239 RPL11 6135
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
240 C7orf34  
Affinity Capture-MS Homo sapiens
241 PCDHGA4  
Affinity Capture-MS Homo sapiens
242 EFNA4  
Affinity Capture-MS Homo sapiens
243 PPM1M  
Affinity Capture-MS Homo sapiens
244 TSSC1 7260
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
245 METTL14  
Affinity Capture-MS Homo sapiens
246 AIM1L  
Affinity Capture-MS Homo sapiens
247 ECT2 1894
Affinity Capture-MS Homo sapiens
248 PCDHAC1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
249 EEF2 1938
Co-fractionation Homo sapiens
250 PDGFRA 5156
Affinity Capture-MS Homo sapiens
251 RPL21 6144
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
252 FBXO6 26270
Affinity Capture-MS Homo sapiens
253 LAMTOR5 10542
Affinity Capture-MS Homo sapiens
254 NCAPH 23397
Affinity Capture-MS Homo sapiens
255 NOS2  
Affinity Capture-MS Homo sapiens
256 PCDH10 57575
Affinity Capture-MS Homo sapiens
257 RPS13 6207
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
258 SCGB2A2  
Affinity Capture-MS Homo sapiens
259 MTOR 2475
Affinity Capture-Western Homo sapiens
260 RPS14 6208
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
261 RPL12 6136
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
262 RPL22 6146
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
263 RPL18 6141
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
264 ISLR 3671
Affinity Capture-MS Homo sapiens
265 Eif3e 16341
Affinity Capture-MS Mus musculus
266 PCDHAC2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
267 TUBB2A 7280
Affinity Capture-MS Homo sapiens
268 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
269 RPL3L 6123
Co-fractionation Homo sapiens
270 CDC20 991
Affinity Capture-MS Homo sapiens
271 RPS25 6230
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
272 FBXL6  
Affinity Capture-MS Homo sapiens
273 TOR1AIP2 163590
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
274 RPL6 6128
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
275 RPS21 6227
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
276 SEZ6  
Affinity Capture-MS Homo sapiens
277 EFNA1  
Affinity Capture-MS Homo sapiens
278 HNRNPM 4670
Co-fractionation Homo sapiens
279 G3BP1 10146
Affinity Capture-MS Homo sapiens
280 CDH23 64072
Affinity Capture-MS Homo sapiens
281 RPL34 6164
Co-fractionation Homo sapiens
282 PDZD8 118987
Affinity Capture-MS Homo sapiens
283 UFL1 23376
Affinity Capture-MS Homo sapiens
284 PPP1R9A  
Affinity Capture-MS Homo sapiens
285 RPL38 6169
Co-fractionation Homo sapiens
286 API5 8539
Affinity Capture-MS Homo sapiens
287 PCDHGA9  
Affinity Capture-MS Homo sapiens
288 RPS7 6201
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
289 RPL8 6132
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
290 METTL3  
Affinity Capture-MS Homo sapiens
291 RPL28 6158
Co-fractionation Homo sapiens
292 RPS27L 51065
Co-fractionation Homo sapiens
293 SERBP1 26135
Affinity Capture-MS Homo sapiens
294 AR 367
Affinity Capture-MS Homo sapiens
295 RC3H1 149041
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
296 ATXN3 4287
Affinity Capture-MS Homo sapiens
297 PCDHGA7 56108
Affinity Capture-MS Homo sapiens
298 ATG3 64422
Co-fractionation Homo sapiens
299 PCDHB3  
Affinity Capture-MS Homo sapiens
300 CAPN2 824
Affinity Capture-MS Homo sapiens
301 RPSA 3921
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
302 RAMP3  
Affinity Capture-MS Homo sapiens
303 RPS3A 6189
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
304 RPL30 6156
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
305 PPIE 10450
Affinity Capture-MS Homo sapiens
306 RPL13A 23521
Co-fractionation Homo sapiens
307 RPL37A 6168
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
308 ASGR2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
309 RPL10 6134
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
310 RPL15 6138
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
311 CALM1 801
Affinity Capture-MS Homo sapiens
312 CD79A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
313 APP 351
Reconstituted Complex Homo sapiens
314 ILF2 3608
Co-fractionation Homo sapiens
315 USP36  
Affinity Capture-MS Homo sapiens
316 ASB17  
Affinity Capture-MS Homo sapiens
317 TOP2A 7153
Affinity Capture-MS Homo sapiens
318 RPS20 6224
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
319 PCK1 5105
Affinity Capture-MS Homo sapiens
320 MRPL23 6150
Co-fractionation Homo sapiens
321 COPS5 10987
Affinity Capture-MS Homo sapiens
322 RPL24 6152
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
323 PSMD9 5715
Affinity Capture-MS Homo sapiens
324 MRPL12 6182
Co-fractionation Homo sapiens
325 RPS8 6202
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
326 EXD2  
Proximity Label-MS Homo sapiens
327 EED  
Affinity Capture-MS Homo sapiens
328 CEP57  
Affinity Capture-MS Homo sapiens
329 MYCN  
Affinity Capture-MS Homo sapiens
330 PSMC3 5702
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
331 RPS23 6228
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
332 NDUFS4 4724
Co-fractionation Homo sapiens
333 LOXL3 84695
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
334 RPL39 6170
Co-fractionation Homo sapiens
335 ERBB3 2065
Affinity Capture-MS Homo sapiens
336 CLSTN1 22883
Affinity Capture-MS Homo sapiens
337 PCDHB11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
338 VCP 7415
Affinity Capture-MS Homo sapiens
339 PYCRL 65263
Affinity Capture-MS Homo sapiens
340 RPL27A 6157
Co-fractionation Homo sapiens
341 CEP76  
Affinity Capture-MS Homo sapiens
342 RPS15A 6210
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
343 MRPS14  
Co-fractionation Homo sapiens
344 PCDHGC5  
Affinity Capture-MS Homo sapiens
345 DAXX  
Affinity Capture-MS Homo sapiens
346 LY86  
Affinity Capture-MS Homo sapiens
347 LIMA1 51474
Affinity Capture-MS Homo sapiens
348 PCDHGB1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
349 PCDHB7  
Affinity Capture-MS Homo sapiens
350 RPLP2 6181
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
351 FANCD2  
Affinity Capture-MS Homo sapiens
352 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
353 OTUD1 220213
Affinity Capture-MS Homo sapiens
354 DNAJC2 27000
Affinity Capture-MS Homo sapiens
355 RPL35 11224
Co-fractionation Homo sapiens
356 CTNNB1 1499
Affinity Capture-MS Homo sapiens
357 KCTD12 115207
Affinity Capture-MS Homo sapiens
358 SLC9A3R1 9368
Co-fractionation Homo sapiens
359 Rrbp1  
Affinity Capture-MS Mus musculus
360 RPL3 6122
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
361 GAA 2548
Affinity Capture-MS Homo sapiens
362 RPL7 6129
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
363 EPHA7 2045
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
364 AGO4  
Affinity Capture-MS Homo sapiens
365 FSCN1 6624
Affinity Capture-MS Homo sapiens
366 BMP4 652
Affinity Capture-MS Homo sapiens
367 MDM2  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
368 NEXN 91624
Affinity Capture-MS Homo sapiens
369 TUBG1 7283
Affinity Capture-MS Homo sapiens
370 HLA-DRA 3122
Affinity Capture-MS Homo sapiens
371 DNAJA2 10294
Affinity Capture-MS Homo sapiens
372 ZNF746  
Affinity Capture-MS Homo sapiens
373 SMURF1 57154
Affinity Capture-MS Homo sapiens
374 RPS15 6209
Co-fractionation Homo sapiens
375 COL6A2 1292
Affinity Capture-MS Homo sapiens
376 RPS28 6234
Co-fractionation Homo sapiens
377 KIAA1429 25962
Affinity Capture-MS Homo sapiens
378 HLA-DPA1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
379 CELSR2  
Affinity Capture-MS Homo sapiens
380 TRIP4 9325
Affinity Capture-MS Homo sapiens
381 TRIM31  
Affinity Capture-MS Homo sapiens
382 RPS6 6194
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
383 HNRNPU 3192
Affinity Capture-MS Homo sapiens
384 C9orf72  
Affinity Capture-MS Homo sapiens
385 RPL17 6139
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
386 CNDP2 55748
Co-fractionation Homo sapiens
View the network image/svg+xml
 Pathways in which RPL23 is involved
PathwayEvidenceSource
Axon guidance IEA Reactome
Cap-dependent Translation Initiation TAS Reactome
Cellular response to starvation IEA Reactome
Cellular responses to stimuli IEA Reactome
Cellular responses to stress IEA Reactome
Developmental Biology IEA Reactome
Disease TAS Reactome
Eukaryotic Translation Elongation IEA Reactome
Eukaryotic Translation Initiation TAS Reactome
Eukaryotic Translation Termination IEA Reactome
Formation of a pool of free 40S subunits TAS Reactome
GTP hydrolysis and joining of the 60S ribosomal subunit TAS Reactome
Infectious disease TAS Reactome
Influenza Infection TAS Reactome
Influenza Viral RNA Transcription and Replication TAS Reactome
L13a-mediated translational silencing of Ceruloplasmin expression TAS Reactome
Major pathway of rRNA processing in the nucleolus and cytosol TAS Reactome
Metabolism IEA Reactome
Metabolism of amino acids and derivatives IEA Reactome
Metabolism of proteins TAS Reactome
Metabolism of proteins IEA Reactome
Metabolism of RNA TAS Reactome
Nervous system development IEA Reactome
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) TAS Reactome
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) TAS Reactome
Nonsense-Mediated Decay (NMD) TAS Reactome
Peptide chain elongation IEA Reactome
Regulation of expression of SLITs and ROBOs IEA Reactome
Response of EIF2AK4 (GCN2) to amino acid deficiency IEA Reactome
rRNA processing TAS Reactome
rRNA processing in the nucleus and cytosol TAS Reactome
Selenoamino acid metabolism IEA Reactome
Selenocysteine synthesis IEA Reactome
Signaling by ROBO receptors IEA Reactome
SRP-dependent cotranslational protein targeting to membrane IEA Reactome
SRP-dependent cotranslational protein targeting to membrane TAS Reactome
Translation TAS Reactome
Translation IEA Reactome
Viral Infection Pathways TAS Reactome
Viral mRNA Translation TAS Reactome





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