Gene description for PDIA4
Gene name protein disulfide isomerase family A, member 4
Gene symbol PDIA4
Other names/aliases ERP70
ERP72
ERp-72
Species Homo sapiens
 Database cross references - PDIA4
ExoCarta ExoCarta_9601
Vesiclepedia VP_9601
Entrez Gene 9601
HGNC 30167
UniProt P13667  
 PDIA4 identified in sEVs derived from the following tissue/cell type
Bladder cancer cells 20224111    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 35918900    
Breast cancer cells 35918900    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 25890246    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Endothelial cells 26027894    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Nasopharyngeal carcinoma cells 25857718    
Nasopharyngeal carcinoma cells 25857718    
Nasopharyngeal carcinoma cells 25857718    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for PDIA4
Molecular Function
    RNA binding GO:0003723 HDA
    protein disulfide isomerase activity GO:0003756 IBA
    protein disulfide isomerase activity GO:0003756 ISS
    protein binding GO:0005515 IPI
    protein-disulfide reductase activity GO:0015035 IDA
Biological Process
    protein folding GO:0006457 IBA
    protein secretion GO:0009306 TAS
    response to endoplasmic reticulum stress GO:0034976 IBA
    chaperone-mediated protein folding GO:0061077 ISS
Subcellular Localization
    extracellular space GO:0005615 IDA
    endoplasmic reticulum GO:0005783 IBA
    endoplasmic reticulum lumen GO:0005788 IEA
    cell surface GO:0009986 IBA
    cell surface GO:0009986 IDA
    melanosome GO:0042470 IEA
 Experiment description of studies that identified PDIA4 in sEVs
1
Experiment ID 76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
2
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
8
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 1333
MISEV standards
Biophysical techniques
✔
CD81|EPCAM|CD9
Enriched markers
✘ Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
Western blotting
11
Experiment ID 1333
MISEV standards
Biophysical techniques
✔
CD81|EPCAM|CD9
Enriched markers
✘ Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
Western blotting
12
Experiment ID 1335
MISEV standards
Biophysical techniques
✔
EPCAM|CD9
Enriched markers
✘ Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
13
Experiment ID 1335
MISEV standards
Biophysical techniques
✔
EPCAM|CD9
Enriched markers
✘ Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
14
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 283
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
18
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
22
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 226
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD9|FLOT1
Enriched markers
✔
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
✘ Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
24
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
26
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
27
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
28
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 258
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
31
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
32
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
33
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
34
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 219
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name C666-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
36
Experiment ID 220
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name NP69
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
37
Experiment ID 221
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name NP460
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
38
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
39
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
40
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
41
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
42
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
43
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
44
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
45
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
46
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
47
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
48
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
49
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
50
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
51
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
52
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PDIA4
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ITGB1 3688
Proximity Label-MS Homo sapiens
2 LAIR2  
Affinity Capture-MS Homo sapiens
3 PTMS 5763
Affinity Capture-MS Homo sapiens
4 ERO1L 30001
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
5 GADD45G  
Two-hybrid Homo sapiens
6 DPY19L3  
Proximity Label-MS Homo sapiens
7 PARK7 11315
Affinity Capture-MS Homo sapiens
8 AKAP8L  
Co-fractionation Homo sapiens
9 APEX1 328
Cross-Linking-MS (XL-MS) Homo sapiens
10 SLC35A3  
Proximity Label-MS Homo sapiens
11 LAMC1 3915
Proximity Label-MS Homo sapiens
12 ACTR3 10096
Proximity Label-MS Homo sapiens
13 HYOU1 10525
Proximity Label-MS Homo sapiens
14 CDH2 1000
Co-fractionation Homo sapiens
15 AI837181  
Affinity Capture-MS Mus musculus
16 SEL1L 6400
Proximity Label-MS Homo sapiens
17 LIPG 9388
Affinity Capture-MS Homo sapiens
18 LMAN2 10960
Proximity Label-MS Homo sapiens
19 FKBP10 60681
Proximity Label-MS Homo sapiens
20 TFRC 7037
Proximity Label-MS Homo sapiens
21 KIF14 9928
Affinity Capture-MS Homo sapiens
22 EMC1 23065
Proximity Label-MS Homo sapiens
23 CHMP4C 92421
Affinity Capture-MS Homo sapiens
24 VAV1 7409
Affinity Capture-MS Homo sapiens
25 TMX1 81542
Proximity Label-MS Homo sapiens
26 KRTAP12-1  
Two-hybrid Homo sapiens
27 UGT8  
Proximity Label-MS Homo sapiens
28 DYNC1I2 1781
Co-fractionation Homo sapiens
29 TMTC3 160418
Proximity Label-MS Homo sapiens
30 TUFM 7284
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
31 MAGT1 84061
Proximity Label-MS Homo sapiens
32 KDELC2 143888
Proximity Label-MS Homo sapiens
33 IDS  
Affinity Capture-MS Homo sapiens
34 CLCC1 23155
Proximity Label-MS Homo sapiens
35 NUDC 10726
Co-fractionation Homo sapiens
36 TRIM21 6737
Affinity Capture-MS Homo sapiens
37 Inpp5b  
Affinity Capture-MS Mus musculus
38 PIGT 51604
Proximity Label-MS Homo sapiens
39 SAR1B 51128
Affinity Capture-MS Homo sapiens
40 SYNE1 23345
Cross-Linking-MS (XL-MS) Homo sapiens
41 P4HB 5034
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
42 B4GALT3 8703
Proximity Label-MS Homo sapiens
43 DDX39B 7919
Affinity Capture-MS Homo sapiens
44 SND1 27044
Cross-Linking-MS (XL-MS) Homo sapiens
45 SEC61B 10952
Proximity Label-MS Homo sapiens
46 MTSS1L 92154
Affinity Capture-MS Homo sapiens
47 NUCB2 4925
Proximity Label-MS Homo sapiens
48 VLDLR 7436
Proximity Label-MS Homo sapiens
49 HIST1H2BL 8340
Cross-Linking-MS (XL-MS) Homo sapiens
50 DNAJB14  
Proximity Label-MS Homo sapiens
51 RNF40 9810
Cross-Linking-MS (XL-MS) Homo sapiens
52 ADAMTS4  
Affinity Capture-MS Homo sapiens
53 TTC13  
Proximity Label-MS Homo sapiens
54 AHCYL1 10768
Co-fractionation Homo sapiens
55 BAG1 573
Affinity Capture-MS Homo sapiens
56 LRRC59 55379
Proximity Label-MS Homo sapiens
57 SIRT7  
Affinity Capture-MS Homo sapiens
58 GGH 8836
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 LAMB1 3912
Proximity Label-MS Homo sapiens
60 BCAP31 10134
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
61 ATP6AP2 10159
Proximity Label-MS Homo sapiens
62 WDR55  
Co-fractionation Homo sapiens
63 ATP1B3 483
Cross-Linking-MS (XL-MS) Homo sapiens
64 ERP29 10961
Proximity Label-MS Homo sapiens
65 IL5RA  
Affinity Capture-MS Homo sapiens
66 ZMPSTE24 10269
Proximity Label-MS Homo sapiens
67 RPA3 6119
Proximity Label-MS Homo sapiens
68 NUCB1 4924
Proximity Label-MS Homo sapiens
69 NCLN 56926
Proximity Label-MS Homo sapiens
70 HSPA4 3308
Cross-Linking-MS (XL-MS) Homo sapiens
71 GXYLT1 283464
Proximity Label-MS Homo sapiens
72 STMN1 3925
Affinity Capture-MS Homo sapiens
73 P3H3 10536
Proximity Label-MS Homo sapiens
74 ENPP7 339221
Affinity Capture-MS Homo sapiens
75 DNASE1L1 1774
Affinity Capture-MS Homo sapiens
76 PCSK9 255738
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
77 EIF2B1 1967
Affinity Capture-MS Homo sapiens
78 LDLR 3949
Affinity Capture-Western Homo sapiens
79 PEX3 8504
Proximity Label-MS Homo sapiens
80 ZBED9 114821
Cross-Linking-MS (XL-MS) Homo sapiens
81 PAFAH1B1 5048
Co-fractionation Homo sapiens
82 HSPE1 3336
Affinity Capture-MS Homo sapiens
83 GSS 2937
Co-fractionation Homo sapiens
84 CKAP2L  
Cross-Linking-MS (XL-MS) Homo sapiens
85 EMC7 56851
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
86 CLPTM1 1209
Proximity Label-MS Homo sapiens
87 SDF4 51150
Proximity Label-MS Homo sapiens
88 DCTN2 10540
Co-fractionation Homo sapiens
89 TKT 7086
Affinity Capture-MS Homo sapiens
90 SUPT4H1  
Cross-Linking-MS (XL-MS) Homo sapiens
91 NCR3  
Affinity Capture-MS Homo sapiens
92 PPP1R2 5504
Co-fractionation Homo sapiens
93 SUPT6H 6830
Cross-Linking-MS (XL-MS) Homo sapiens
94 CEP78 84131
Affinity Capture-MS Homo sapiens
95 CST11  
Affinity Capture-MS Homo sapiens
96 CUL7 9820
Affinity Capture-MS Homo sapiens
97 COLGALT1 79709
Proximity Label-MS Homo sapiens
98 LCN2 3934
Two-hybrid Homo sapiens
99 SNX29  
Affinity Capture-MS Homo sapiens
100 FKBP2 2286
Proximity Label-MS Homo sapiens
101 BRI3BP 140707
Proximity Label-MS Homo sapiens
102 PIGS 94005
Proximity Label-MS Homo sapiens
103 UGGT2 55757
Proximity Label-MS Homo sapiens
104 SEP15 9403
Proximity Label-MS Homo sapiens
105 ANP32A 8125
Affinity Capture-MS Homo sapiens
106 NACA 4666
Affinity Capture-MS Homo sapiens
107 SLC35B4  
Proximity Label-MS Homo sapiens
108 NOP56 10528
Proximity Label-MS Homo sapiens
109 PACSIN2 11252
Co-fractionation Homo sapiens
110 TRIM33 51592
Affinity Capture-MS Homo sapiens
111 NENF 29937
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
112 LGALS3BP 3959
Proximity Label-MS Homo sapiens
113 PGK1 5230
Affinity Capture-MS Homo sapiens
114 B3GNT2 10678
Affinity Capture-MS Homo sapiens
115 TMED2 10959
Proximity Label-MS Homo sapiens
116 OS9 10956
Proximity Label-MS Homo sapiens
117 OBSL1 23363
Affinity Capture-MS Homo sapiens
118 YWHAH 7533
Co-fractionation Homo sapiens
119 SERF2 10169
Cross-Linking-MS (XL-MS) Homo sapiens
120 PCYOX1 51449
Proximity Label-MS Homo sapiens
121 YWHAB 7529
Affinity Capture-MS Homo sapiens
122 B3GALTL 145173
Proximity Label-MS Homo sapiens
123 PFN1 5216
Affinity Capture-MS Homo sapiens
124 NAE1 8883
Co-fractionation Homo sapiens
125 HIST1H4A 8359
Cross-Linking-MS (XL-MS) Homo sapiens
126 TRIM24  
Affinity Capture-MS Homo sapiens
127 TMEM43 79188
Proximity Label-MS Homo sapiens
128 TRIM16 10626
Co-fractionation Homo sapiens
129 APMAP 57136
Proximity Label-MS Homo sapiens
130 ARHGEF6 9459
Affinity Capture-MS Homo sapiens
131 TMEM131  
Proximity Label-MS Homo sapiens
132 ALDH7A1 501
Co-fractionation Homo sapiens
133 NOMO2 283820
Proximity Label-MS Homo sapiens
134 RPN2 6185
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
135 CANX 821
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
136 CCDC134 79879
Proximity Label-MS Homo sapiens
137 UGGT1 56886
Proximity Label-MS Homo sapiens
138 EIF6 3692
Affinity Capture-MS Homo sapiens
139 JADE1  
Cross-Linking-MS (XL-MS) Homo sapiens
140 KRTAP10-8  
Two-hybrid Homo sapiens
141 PRCP 5547
Co-fractionation Homo sapiens
142 MYO1E 4643
Co-fractionation Homo sapiens
143 CMTM2  
Cross-Linking-MS (XL-MS) Homo sapiens
144 CDK2 1017
Affinity Capture-MS Homo sapiens
145 HMGB3 3149
Co-fractionation Homo sapiens
146 RCN2 5955
Proximity Label-MS Homo sapiens
147 FKBP3 2287
Affinity Capture-MS Homo sapiens
148 ISOC1 51015
Co-fractionation Homo sapiens
149 PCYOX1L 78991
Proximity Label-MS Homo sapiens
150 PGAM1 5223
Affinity Capture-MS Homo sapiens
151 HMGB1P1 10357
Affinity Capture-MS Homo sapiens
152 SOD1 6647
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
153 LYZL2  
Affinity Capture-MS Homo sapiens
154 SUN1 23353
Proximity Label-MS Homo sapiens
155 PRKCSH 5589
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
156 STK24 8428
Co-fractionation Homo sapiens
157 TXNDC16 57544
Proximity Label-MS Homo sapiens
158 ILF3 3609
Co-fractionation Homo sapiens
159 TP53 7157
Affinity Capture-MS Homo sapiens
160 CALU 813
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
161 SEC11A 23478
Proximity Label-MS Homo sapiens
162 Arhgap30  
Affinity Capture-MS Mus musculus
163 STK26 51765
Co-fractionation Homo sapiens
164 TOR1AIP1 26092
Proximity Label-MS Homo sapiens
165 PLD3 23646
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
166 BCL2L1 598
Two-hybrid Homo sapiens
167 ANXA5 308
Affinity Capture-MS Homo sapiens
168 ALPP 250
Affinity Capture-MS Homo sapiens
169 IGF2R 3482
Proximity Label-MS Homo sapiens
170 DDX42 11325
Cross-Linking-MS (XL-MS) Homo sapiens
171 ARHGAP23 57636
Affinity Capture-MS Homo sapiens
172 CKAP4 10970
Proximity Label-MS Homo sapiens
173 PRMT1 3276
Co-fractionation Homo sapiens
174 COL6A1 1291
Proximity Label-MS Homo sapiens
175 MARCKS 4082
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
176 PTMA 5757
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
177 YWHAE 7531
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
178 MANF 7873
Proximity Label-MS Homo sapiens
179 PEBP1 5037
Affinity Capture-MS Homo sapiens
180 ERO1LB 56605
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
181 PLOD3 8985
Proximity Label-MS Homo sapiens
182 MCM2 4171
Co-fractionation Homo sapiens
183 AHSG 197
Affinity Capture-MS Homo sapiens
184 ERAP1 51752
Proximity Label-MS Homo sapiens
185 NUP210 23225
Cross-Linking-MS (XL-MS) Homo sapiens
Proximity Label-MS Homo sapiens
186 PDIA6 10130
Proximity Label-MS Homo sapiens
187 CCDC47 57003
Proximity Label-MS Homo sapiens
188 PRDX4 10549
Proximity Label-MS Homo sapiens
189 CALR 811
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
190 Arap3  
Affinity Capture-MS Mus musculus
191 CTAGE5 4253
Proximity Label-MS Homo sapiens
192 RBM8A 9939
Affinity Capture-MS Homo sapiens
193 CHID1 66005
Proximity Label-MS Homo sapiens
194 PXMP2  
Proximity Label-MS Homo sapiens
195 P4HA1 5033
Proximity Label-MS Homo sapiens
196 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
197 RALA 5898
Cross-Linking-MS (XL-MS) Homo sapiens
198 SRRT 51593
Co-fractionation Homo sapiens
199 PLOD2 5352
Proximity Label-MS Homo sapiens
200 TUBA1B 10376
Co-fractionation Homo sapiens
201 SDF2L1 23753
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
202 NTRK1 4914
Affinity Capture-MS Homo sapiens
203 PPME1 51400
Affinity Capture-MS Homo sapiens
204 RPN1 6184
Proximity Label-MS Homo sapiens
205 AMPD2 271
Co-fractionation Homo sapiens
206 RMDN3 55177
Proximity Label-MS Homo sapiens
207 EMC3 55831
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
208 PREX1  
Affinity Capture-MS Homo sapiens
209 DNAJB12 54788
Proximity Label-MS Homo sapiens
210 B3GNT3 10331
Affinity Capture-MS Homo sapiens
211 PDGFRA 5156
Affinity Capture-MS Homo sapiens
212 STIM1 6786
Proximity Label-MS Homo sapiens
213 CBLN4  
Affinity Capture-MS Homo sapiens
214 RCN1 5954
Proximity Label-MS Homo sapiens
215 DNAJC18  
Proximity Label-MS Homo sapiens
216 PTPRN  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
217 DNAJC10 54431
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
218 DNAJC3 5611
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
219 DHFRL1  
Proximity Label-MS Homo sapiens
220 TXNDC5 81567
Proximity Label-MS Homo sapiens
221 MSN 4478
Co-fractionation Homo sapiens
222 AKAP1 8165
Proximity Label-MS Homo sapiens
223 TPM3 7170
Affinity Capture-MS Homo sapiens
224 PROSC 11212
Co-fractionation Homo sapiens
225 SUMF2 25870
Proximity Label-MS Homo sapiens
226 SPCS3 60559
Proximity Label-MS Homo sapiens
227 TMED10 10972
Proximity Label-MS Homo sapiens
228 TOR1AIP2 163590
Proximity Label-MS Homo sapiens
229 ERLIN1 10613
Proximity Label-MS Homo sapiens
230 KDELC1 79070
Proximity Label-MS Homo sapiens
231 MLEC 9761
Proximity Label-MS Homo sapiens
232 CNPY2 10330
Proximity Label-MS Homo sapiens
233 SIL1 64374
Proximity Label-MS Homo sapiens
234 ERLIN2 11160
Proximity Label-MS Homo sapiens
235 PLOD1 5351
Proximity Label-MS Homo sapiens
236 ERGIC1 57222
Proximity Label-MS Homo sapiens
237 DDX58 23586
Affinity Capture-RNA Homo sapiens
238 MIF 4282
Affinity Capture-MS Homo sapiens
239 DNAJC5B  
Proximity Label-MS Homo sapiens
240 RPS7 6201
Co-fractionation Homo sapiens
241 RPRD1B 58490
Affinity Capture-MS Homo sapiens
242 SERBP1 26135
Affinity Capture-MS Homo sapiens
243 STT3B 201595
Proximity Label-MS Homo sapiens
244 CLPTM1L 81037
Proximity Label-MS Homo sapiens
245 Shcbp1 20419
Affinity Capture-MS Mus musculus
246 GPX7 2882
Affinity Capture-MS Homo sapiens
247 ZNF318 24149
Cross-Linking-MS (XL-MS) Homo sapiens
248 EP300 2033
Affinity Capture-MS Homo sapiens
249 HLA-C 3107
Proximity Label-MS Homo sapiens
250 CAPN2 824
Co-fractionation Homo sapiens
251 UBE2H 7328
Affinity Capture-MS Homo sapiens
252 ARHGAP21 57584
Affinity Capture-MS Homo sapiens
253 ATPIF1 93974
Affinity Capture-MS Homo sapiens
254 TWF2 11344
Co-fractionation Homo sapiens
255 FBN2 2201
Proximity Label-MS Homo sapiens
256 OGFOD1  
Co-fractionation Homo sapiens
257 WWP1 11059
Affinity Capture-MS Homo sapiens
258 ARSA 410
Affinity Capture-MS Homo sapiens
259 POFUT1 23509
Proximity Label-MS Homo sapiens
260 P4HA2 8974
Proximity Label-MS Homo sapiens
261 ERAP2 64167
Proximity Label-MS Homo sapiens
262 HSPA13 6782
Proximity Label-MS Homo sapiens
263 ECEL1  
Affinity Capture-MS Homo sapiens
264 PLD4  
Affinity Capture-MS Homo sapiens
265 DNAJC25 548645
Proximity Label-MS Homo sapiens
266 CALM1 801
Affinity Capture-MS Homo sapiens
267 GRAMD1A  
Proximity Label-MS Homo sapiens
268 CCDC124 115098
Cross-Linking-MS (XL-MS) Homo sapiens
269 COL12A1 1303
Cross-Linking-MS (XL-MS) Homo sapiens
270 HSPA5 3309
Proximity Label-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Proximity Label-MS Homo sapiens
271 HIST1H2BD 3017
Cross-Linking-MS (XL-MS) Homo sapiens
272 TBCB 1155
Co-fractionation Homo sapiens
273 PRDX3 10935
Affinity Capture-MS Homo sapiens
274 ANP32B 10541
Affinity Capture-MS Homo sapiens
275 SCRIB 23513
Cross-Linking-MS (XL-MS) Homo sapiens
276 YWHAG 7532
Affinity Capture-MS Homo sapiens
277 BASP1 10409
Affinity Capture-MS Homo sapiens
278 DDOST 1650
Proximity Label-MS Homo sapiens
279 VWF 7450
Affinity Capture-Western Homo sapiens
280 SERPINH1 871
Proximity Label-MS Homo sapiens
281 DNAJC16  
Proximity Label-MS Homo sapiens
282 TATDN1 83940
Co-fractionation Homo sapiens
283 GUSB 2990
Proximity Label-MS Homo sapiens
284 P3H1 64175
Proximity Label-MS Homo sapiens
285 NEDD4 4734
Affinity Capture-MS Homo sapiens
286 CPNE3 8895
Co-fractionation Homo sapiens
287 APOO 79135
Proximity Label-MS Homo sapiens
288 E2F4  
Affinity Capture-MS Homo sapiens
289 CALR3  
Proximity Label-MS Homo sapiens
290 PPIB 5479
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
291 IKBIP 121457
Proximity Label-MS Homo sapiens
292 PSMD4 5710
Co-fractionation Homo sapiens
293 HSP90B1 7184
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
294 ATF2  
Affinity Capture-MS Homo sapiens
295 GCC2 9648
Co-fractionation Homo sapiens
296 VCL 7414
Co-fractionation Homo sapiens
297 HMGN1  
Affinity Capture-MS Homo sapiens
298 IFI16 3428
Affinity Capture-MS Homo sapiens
299 DNAJB9 4189
Proximity Label-MS Homo sapiens
300 SUMO2 6613
Affinity Capture-MS Homo sapiens
301 MIA3 375056
Proximity Label-MS Homo sapiens
302 MOGS 7841
Proximity Label-MS Homo sapiens
303 PCLO 27445
Cross-Linking-MS (XL-MS) Homo sapiens
304 GANAB 23193
Proximity Label-MS Homo sapiens
305 MYH10 4628
Co-fractionation Homo sapiens
306 DNAJC30  
Proximity Label-MS Homo sapiens
307 LYPD4  
Affinity Capture-MS Homo sapiens
308 PTPRO 5800
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
309 CEBPA  
Protein-peptide Homo sapiens
310 DNAJB11 51726
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
311 COX4I1 1327
Proximity Label-MS Homo sapiens
312 COL14A1 7373
Proximity Label-MS Homo sapiens
313 MESDC2 23184
Proximity Label-MS Homo sapiens
314 SEC63 11231
Proximity Label-MS Homo sapiens
315 FGD5  
Affinity Capture-MS Homo sapiens
316 UBE2N 7334
Proximity Label-MS Homo sapiens
317 RAP1GDS1 5910
Co-fractionation Homo sapiens
318 DOCK7 85440
Affinity Capture-MS Homo sapiens
319 APOB 338
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-RNA Homo sapiens
320 Bmpr1a  
Affinity Capture-MS Mus musculus
321 NAA15 80155
Co-fractionation Homo sapiens
322 PDIA3 2923
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
323 CNPY3 10695
Proximity Label-MS Homo sapiens
324 ERP44 23071
Proximity Label-MS Homo sapiens
325 IRF8  
Proximity Label-MS Homo sapiens
326 ASPH 444
Proximity Label-MS Homo sapiens
327 FIP1L1 81608
Co-fractionation Homo sapiens
328 MGEA5 10724
Co-fractionation Homo sapiens
329 DOCK3  
Affinity Capture-MS Homo sapiens
330 CCDC8  
Affinity Capture-MS Homo sapiens
331 EIF3D 8664
Co-fractionation Homo sapiens
332 H2AFX 3014
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
333 TTC17 55761
Proximity Label-MS Homo sapiens
334 PDIA5 10954
Proximity Label-MS Homo sapiens
335 FOXRED2  
Proximity Label-MS Homo sapiens
336 ASNS 440
Co-fractionation Homo sapiens
337 PAFAH1B2 5049
Co-fractionation Homo sapiens
338 LMAN1 3998
Proximity Label-MS Homo sapiens
339 PIGK 10026
Proximity Label-MS Homo sapiens
340 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
341 CAPNS1 826
Co-fractionation Homo sapiens
342 LRPAP1 4043
Proximity Label-MS Homo sapiens
343 PINK1  
Affinity Capture-MS Homo sapiens
344 MINPP1 9562
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which PDIA4 is involved
No pathways found





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