Gene description for RPRD1B
Gene name regulation of nuclear pre-mRNA domain containing 1B
Gene symbol RPRD1B
Other names/aliases C20orf77
Species Homo sapiens
 Database cross references - RPRD1B
ExoCarta ExoCarta_58490
Entrez Gene 58490
HGNC 16209
MIM 614694
UniProt Q9NQG5  
 RPRD1B identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells 20124223    
 Gene ontology annotations for RPRD1B
Molecular Function
    protein binding GO:0005515 IPI
    RNA polymerase II core binding GO:0000993 IDA
Biological Process
    positive regulation of cell proliferation GO:0008284 IDA
    dephosphorylation of RNA polymerase II C-terminal domain GO:0070940 IMP
    regulation of cell cycle process GO:0010564 IDA
    positive regulation of transcription from RNA polymerase II promoter GO:0045944 IDA
    transcription, DNA-templated GO:0006351 IEA
Subcellular Localization
    DNA-directed RNA polymerase II, holoenzyme GO:0016591 IDA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified RPRD1B in exosomes
Experiment ID 191
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RPRD1B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TUBGCP4 27229
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which RPRD1B is involved
No pathways found

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