Gene description for NT5C2
Gene name
5'-nucleotidase, cytosolic II
Gene symbol
NT5C2
Other names/aliases
GMP NT5B PNT5 SPG45 SPG65 cN-II
Species
Homo sapiens
Database cross references - NT5C2
ExoCarta
ExoCarta_22978
Entrez Gene
22978
HGNC
8022
MIM
600417
UniProt
P49902
NT5C2 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells
23333927
Ovarian cancer cells
23333927
Gene ontology annotations for NT5C2
Experiment description of studies that identified NT5C2 in exosomes
1
Experiment ID
211
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
cytochrome c|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
2
Experiment ID
212
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
Cytochrome C|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for NT5C2
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
FLJ22494
Two-hybrid
Homo sapiens
2
NT5C2
22978
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
3
MOBKL2B
Two-hybrid
Homo sapiens
4
MGC3162
Two-hybrid
Homo sapiens
5
FXR2
9513
Two-hybrid
Homo sapiens
6
NME7
Two-hybrid
Homo sapiens
View the network
image/svg+xml
Pathways in which NT5C2 is involved