Gene description for UBE3A
Gene name	ubiquitin protein ligase E3A
Gene symbol	UBE3A
Other names/aliases	ANCR AS E6-AP EPVE6AP HPVE6A
Species	Homo sapiens
Database cross references - UBE3A
ExoCarta	ExoCarta_7337
Entrez Gene	7337
HGNC	12496
MIM	601623
UniProt	Q05086
UBE3A identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513

Gene ontology annotations for UBE3A

Molecular Function     metal ion binding GO:0046872 IEA     ligase activity GO:0016874 IEA     protein binding GO:0005515 IPI     transcription coactivator activity GO:0003713 IEA     ubiquitin protein ligase activity GO:0061630 IMP     ubiquitin-protein transferase activity GO:0004842 IDA Biological Process     proteolysis GO:0006508 TAS     brain development GO:0007420 TAS     regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process GO:2000058 IMP     regulation of circadian rhythm GO:0042752 IMP     protein ubiquitination involved in ubiquitin-dependent protein catabolic process GO:0042787 IBA     sperm entry GO:0035037 IEA     ovarian follicle development GO:0001541 IEA     positive regulation of protein ubiquitination GO:0031398 IDA     ubiquitin-dependent protein catabolic process GO:0006511 TAS     prostate gland growth GO:0060736 IEA     positive regulation of transcription from RNA polymerase II promoter GO:0045944 IEA     positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 IEA     protein autoubiquitination GO:0051865 IDA     protein K48-linked ubiquitination GO:0070936 IDA     androgen receptor signaling pathway GO:0030521 IBA     viral process GO:0016032 IEA Subcellular Localization     cytosol GO:0005829 IEA     proteasome complex GO:0000502 IEA     cytoplasm GO:0005737 IBA     nucleus GO:0005634 IEA