Gene description for LMO7
Gene name LIM domain 7
Gene symbol LMO7
Other names/aliases FBX20
Species Homo sapiens
 Database cross references - LMO7
ExoCarta ExoCarta_4008
Entrez Gene 4008
HGNC 6646
MIM 604362
UniProt Q8WWI1  
 LMO7 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for LMO7
Molecular Function
    zinc ion binding GO:0008270 IEA
    ubiquitin-protein transferase activity GO:0004842 NAS
Biological Process
    protein ubiquitination GO:0016567 NAS
    regulation of cell adhesion GO:0030155 IEA
    regulation of signaling GO:0023051 IEA
Subcellular Localization
    ubiquitin ligase complex GO:0000151 NAS
    focal adhesion GO:0005925 IDA
    nucleus GO:0005634 TAS
    cytoplasm GO:0005737 TAS
 Experiment description of studies that identified LMO7 in exosomes
Experiment ID 235
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for LMO7
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SFN 2810
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which LMO7 is involved
No pathways found

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