Gene description for YWHAE
Gene name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
Gene symbol YWHAE
Other names/aliases 14-3-3E
HEL2
KCIP-1
MDCR
MDS
Species Homo sapiens
 Database cross references - YWHAE
ExoCarta ExoCarta_7531
Vesiclepedia VP_7531
Entrez Gene 7531
HGNC 12851
MIM 605066
UniProt P62258  
 YWHAE identified in sEVs derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
B cells 20458337    
Bladder cancer cells 20224111    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 17956143    
Colorectal cancer cells 19837982    
Colorectal cancer cells 22740476    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 25890246    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 36706192    
Embryonic kidney cells 36706192    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Keratinocytes 19530224    
Keratinocytes 19530224    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 15478216    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells Unpublished / Not applicable
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Pluripotent stem cells 34108659    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 25844599    
Prostate cancer cells 25844599    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Saliva 19199708    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
Thymus 23844026    
Urine 15326289    
Urine 19056867    
Urine 21595033    
Urine 21595033    
Urine 21595033    
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for YWHAE
Molecular Function
    RNA binding GO:0003723 HDA
    calcium channel regulator activity GO:0005246 IDA
    protein binding GO:0005515 IPI
    potassium channel regulator activity GO:0015459 IDA
    calcium channel inhibitor activity GO:0019855 IDA
    enzyme binding GO:0019899 IPI
    protein phosphatase binding GO:0019903 IEA
    protein domain specific binding GO:0019904 IEA
    MHC class II protein complex binding GO:0023026 HDA
    ubiquitin protein ligase binding GO:0031625 IPI
    signaling adaptor activity GO:0035591 IDA
    identical protein binding GO:0042802 IPI
    histone deacetylase binding GO:0042826 IPI
    transmembrane transporter binding GO:0044325 IPI
    cadherin binding GO:0045296 HDA
    protein heterodimerization activity GO:0046982 IPI
    phosphoserine residue binding GO:0050815 IBA
    phosphoserine residue binding GO:0050815 IPI
    phosphoprotein binding GO:0051219 IPI
    scaffold protein binding GO:0097110 IPI
    protein sequestering activity GO:0140311 IDA
Biological Process
    MAPK cascade GO:0000165 IDA
    neuron migration GO:0001764 IEA
    cytoplasmic pattern recognition receptor signaling pathway GO:0002753 IDA
    regulation of heart rate by hormone GO:0003064 NAS
    protein targeting GO:0006605 IEA
    signal transduction GO:0007165 IBA
    regulation of mitotic cell cycle GO:0007346 IBA
    protein localization GO:0008104 IBA
    substantia nigra development GO:0021762 HEP
    hippocampus development GO:0021766 IEA
    cerebral cortex development GO:0021987 IEA
    negative regulation of toll-like receptor signaling pathway GO:0034122 IDA
    protein localization to nucleus GO:0034504 IMP
    cellular response to heat GO:0034605 IDA
    positive regulation of hippo signaling GO:0035332 IDA
    intracellular signal transduction GO:0035556 TAS
    positive regulation of protein export from nucleus GO:0046827 IDA
    cytoplasmic sequestering of protein GO:0051220 IDA
    regulation of cytosolic calcium ion concentration GO:0051480 IDA
    regulation of membrane repolarization GO:0060306 IDA
    protein localization to endoplasmic reticulum GO:0070972 IDA
    membrane repolarization during cardiac muscle cell action potential GO:0086013 IC
    regulation of heart rate by cardiac conduction GO:0086091 IC
    regulation of potassium ion transmembrane transport GO:1901379 IDA
    negative regulation of calcium ion export across plasma membrane GO:1905913 IDA
Subcellular Localization
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    cytoplasm GO:0005737 IDA
    endoplasmic reticulum GO:0005783 IDA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 IDA
    focal adhesion GO:0005925 HDA
    membrane GO:0016020 HDA
    mitochondrial membrane GO:0031966 IC
    melanosome GO:0042470 IEA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified YWHAE in sEVs
1
Experiment ID 79
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 80
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 81
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
4
Experiment ID 76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
5
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 494
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
14
Experiment ID 496
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
15
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
16
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
17
Experiment ID 20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
18
Experiment ID 21
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry   
PubMed ID 19837982    
Organism Homo sapiens
Experiment description Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors "Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson"
Journal name MCP
Publication year 2009
Sample Colorectal cancer cells
Sample name LIM1215
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.10-1.12 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [Orbitrap]
Western blotting
19
Experiment ID 201
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22740476    
Organism Homo sapiens
Experiment description Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4.
Authors "Lim JW, Mathias RA, Kapp EA, Layton MJ, Faux MC, Burgess AW, Ji H, Simpson RJ."
Journal name Electrophoresis
Publication year 2012
Sample Colorectal cancer cells
Sample name SW480
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
20
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
21
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
22
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 286
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
24
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
25
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
27
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
28
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
30
Experiment ID 1275
MISEV standards
Biophysical techniques
✔
CD9|TSG101|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
31
Experiment ID 1280
MISEV standards
Biophysical techniques
✔
TSG101|CD9|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T - Fraction 5
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density 1.151 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
32
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
33
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
34
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
35
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
36
Experiment ID 189
MISEV standards
✔
EM
Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Differentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
37
Experiment ID 190
MISEV standards
✔
EM
Biophysical techniques
✔
HSC70
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Undifferentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
38
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
39
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
40
Experiment ID 12
MISEV standards
✔
EM
Biophysical techniques
✔
MHCI
Enriched markers
✔
CANX|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15478216    
Organism Homo sapiens
Experiment description Proteomic analysis of melanoma-derived exosomes by two-dimensional polyacrylamide gel electrophoresis and mass spectrometry.
Authors "Mears R, Craven RA, Hanrahan S, Totty N, Upton C, Young SL, Patel P, Selby PJ, Banks RE"
Journal name PROTEOMICS
Publication year 2004
Sample Melanoma cells
Sample name MeWo
SK-MEL-28
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.20 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [4700 Proteomics Analyzer]
Western blotting
41
Experiment ID 254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
42
Experiment ID 255
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name G1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
43
Experiment ID 256
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
44
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
45
Experiment ID 258
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
46
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
47
Experiment ID 260
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
48
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
49
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
50
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
51
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
52
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
53
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
54
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
55
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
56
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
57
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
58
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
59
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
60
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
61
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
62
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
63
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
64
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
65
Experiment ID 138
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name DU145 - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
66
Experiment ID 139
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name DU145 - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
67
Experiment ID 140
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name VCaP - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
68
Experiment ID 141
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name VCaP - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
69
Experiment ID 144
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name C4-2 - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
70
Experiment ID 145
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|CD10
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name C4-2 - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
71
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
72
Experiment ID 274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
73
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
74
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
75
Experiment ID 66
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG101|Alix|CD63|CD81
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
76
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
77
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
78
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
79
Experiment ID 13
MISEV standards
✔
IEM
Biophysical techniques
✔
Alix|RAB4|RAB5B|RAB11|TSG101|CD9|AQP2|AQP1
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15326289    
Organism Homo sapiens
Experiment description Identification and proteomic profiling of exosomes in human urine.
Authors "Pisitkun T, Shen RF, Knepper MA"
Journal name PNAS
Publication year 2004
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LCQ DECA XP]
Western blotting
80
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
81
Experiment ID 193
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
PHB
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
82
Experiment ID 194
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
83
Experiment ID 195
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
84
Experiment ID 196
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
85
Experiment ID 197
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for YWHAE
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PLEKHA3  
Affinity Capture-MS Homo sapiens
2 EIF3A 8661
Affinity Capture-MS Homo sapiens
3 CEP170B  
Affinity Capture-MS Homo sapiens
4 HDAC4  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 ARHGEF2 9181
Affinity Capture-MS Homo sapiens
6 RASSF8 11228
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 UBL4A 8266
Affinity Capture-MS Homo sapiens
8 LNP1  
Affinity Capture-MS Homo sapiens
9 RALGPS2 55103
Affinity Capture-MS Homo sapiens
10 TBC1D4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 LDHB 3945
Co-fractionation Homo sapiens
12 WNK1 65125
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
13 SH3BP4 23677
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
14 PPP1R3D  
Affinity Capture-MS Homo sapiens
15 DYNC1I2 1781
Affinity Capture-MS Homo sapiens
16 DDX21 9188
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
17 KLC3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 WWC2  
Affinity Capture-MS Homo sapiens
19 NRAP  
Cross-Linking-MS (XL-MS) Homo sapiens
20 MAST4  
Affinity Capture-MS Homo sapiens
21 ACTC1 70
Affinity Capture-MS Homo sapiens
22 UBA1 7317
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
23 MIIP 60672
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 EMD 2010
Affinity Capture-MS Homo sapiens
25 UBE3A 7337
Two-hybrid Homo sapiens
26 CDC25B 994
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
27 SRGAP2 23380
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 N4BP3  
Affinity Capture-MS Homo sapiens
29 EIF4E2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 SOX2  
Affinity Capture-MS Homo sapiens
31 TACC2 10579
Affinity Capture-MS Homo sapiens
32 AMOTL1 154810
Affinity Capture-MS Homo sapiens
33 RB1CC1 9821
Affinity Capture-MS Homo sapiens
34 CKB 1152
Co-fractionation Homo sapiens
35 TCEB3 6924
Co-localization Homo sapiens
36 WDR62  
Affinity Capture-MS Homo sapiens
37 MAP3K5 4217
Affinity Capture-MS Homo sapiens
38 WNK2  
Affinity Capture-MS Homo sapiens
39 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
40 ARL3 403
Affinity Capture-MS Homo sapiens
41 CHAF1A  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
42 KIF23 9493
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 ACAP2 23527
Affinity Capture-MS Homo sapiens
44 RAF1 5894
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 RASAL3 64926
Two-hybrid Homo sapiens
46 SHROOM2 357
Affinity Capture-MS Homo sapiens
47 PLCH1  
Affinity Capture-MS Homo sapiens
48 METAP2 10988
Reconstituted Complex Homo sapiens
49 RAI14 26064
Affinity Capture-MS Homo sapiens
50 CALD1 800
Affinity Capture-MS Homo sapiens
51 ERC1 23085
Affinity Capture-MS Homo sapiens
52 PFDN4 5203
Co-fractionation Homo sapiens
53 MTMR2 8898
Affinity Capture-MS Homo sapiens
54 TLK1  
Two-hybrid Homo sapiens
55 SMC2 10592
Affinity Capture-MS Homo sapiens
56 RASAL2 9462
Affinity Capture-MS Homo sapiens
57 EIF3E 3646
Affinity Capture-MS Homo sapiens
58 CWF19L1 55280
Affinity Capture-MS Homo sapiens
59 FAM86C1  
Affinity Capture-MS Homo sapiens
60 NDUFAB1 4706
Co-fractionation Homo sapiens
61 RIPK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
62 ZNF598 90850
Affinity Capture-MS Homo sapiens
63 NONO 4841
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
64 Wwtr1  
Affinity Capture-MS Mus musculus
65 BTRC 8945
Affinity Capture-MS Homo sapiens
66 TCEANC  
Reconstituted Complex Homo sapiens
67 ARHGEF4  
Affinity Capture-MS Homo sapiens
68 MTA2 9219
Affinity Capture-MS Homo sapiens
69 RAD23A 5886
Co-fractionation Homo sapiens
70 DYNLT1 6993
Affinity Capture-MS Homo sapiens
71 KIF14 9928
Affinity Capture-MS Homo sapiens
72 FAM163A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
73 CLASP2 23122
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
74 AKT1 207
Affinity Capture-MS Homo sapiens
75 RASSF2 9770
Affinity Capture-MS Homo sapiens
76 UNK  
Affinity Capture-RNA Homo sapiens
77 CHMP4C 92421
Affinity Capture-MS Homo sapiens
78 AMOTL2 51421
Affinity Capture-MS Homo sapiens
79 TBC1D3F  
Two-hybrid Homo sapiens
80 MAP3K2 10746
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 CRY1  
Affinity Capture-MS Homo sapiens
82 NCKIPSD 51517
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
83 SORBS2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
84 SAE1 10055
Affinity Capture-MS Homo sapiens
85 MTFR1L 56181
Affinity Capture-MS Homo sapiens
86 ZNF395 55893
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
87 RBM7  
Affinity Capture-MS Homo sapiens
88 RRAS2 22800
Affinity Capture-MS Homo sapiens
89 CAMK2G 818
Affinity Capture-MS Homo sapiens
90 HDAC7  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
91 CDH1 999
Proximity Label-MS Homo sapiens
92 YAP1 10413
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
93 KIF5A 3798
Affinity Capture-MS Homo sapiens
94 KIAA0232 9778
Two-hybrid Homo sapiens
95 OGT 8473
Affinity Capture-MS Homo sapiens
96 SAR1B 51128
Affinity Capture-MS Homo sapiens
97 HLA-DRB5 3127
Affinity Capture-MS Homo sapiens
98 GPSM3  
Affinity Capture-MS Homo sapiens
99 TRIM21 6737
Affinity Capture-MS Homo sapiens
100 NOS2  
Affinity Capture-MS Homo sapiens
101 YWHAQ 10971
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
102 PLEKHO2 80301
Affinity Capture-MS Homo sapiens
103 HECTD1 25831
Affinity Capture-MS Homo sapiens
104 VCL 7414
Co-fractionation Homo sapiens
105 MMP20  
Co-fractionation Homo sapiens
106 ACD  
Two-hybrid Homo sapiens
107 ZFP36L2 678
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
108 ATXN1 6310
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
109 TMPO 7112
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
110 ARHGAP32  
Affinity Capture-MS Homo sapiens
111 FAM83B  
Affinity Capture-MS Homo sapiens
112 C2orf49 79074
Affinity Capture-MS Homo sapiens
113 GPRIN2  
Two-hybrid Homo sapiens
114 PAFAH1B1 5048
Affinity Capture-MS Homo sapiens
115 VAMP8 8673
Affinity Capture-MS Homo sapiens
116 ANKRD55  
Affinity Capture-MS Homo sapiens
117 GSTA1 2938
Two-hybrid Homo sapiens
118 SDHA 6389
Affinity Capture-MS Homo sapiens
119 CDC25A  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
120 SRSF4 6429
Affinity Capture-MS Homo sapiens
121 LMO7 4008
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
122 MAGEB4  
Reconstituted Complex Homo sapiens
123 FOXO1  
Affinity Capture-MS Homo sapiens
124 NPM3 10360
Co-fractionation Homo sapiens
125 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
126 YWHAZ 7534
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
127 POLR2D  
Co-fractionation Homo sapiens
128 WDR37 22884
Affinity Capture-MS Homo sapiens
129 PRPSAP1 5635
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
130 DUSP16  
Affinity Capture-MS Homo sapiens
131 RBBP4 5928
Affinity Capture-MS Homo sapiens
132 FN1 2335
Affinity Capture-MS Homo sapiens
133 PSD4  
Affinity Capture-MS Homo sapiens
134 HEXA 3073
Co-fractionation Homo sapiens
135 WASF1 8936
Affinity Capture-MS Homo sapiens
136 FAM122B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
137 SOAT1 6646
Affinity Capture-MS Homo sapiens
138 PCBP1 5093
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
139 MEX3B 84206
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
140 TJP2 9414
Affinity Capture-MS Homo sapiens
141 CRTC3  
Affinity Capture-MS Homo sapiens
142 RPA3 6119
Proximity Label-MS Homo sapiens
143 SIK1  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
144 GIGYF1  
Affinity Capture-MS Homo sapiens
145 WWC1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
146 DLST 1743
Affinity Capture-MS Homo sapiens
147 NDE1 54820
Affinity Capture-MS Homo sapiens
148 RAB11FIP2  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
149 HSPA1A 3303
Affinity Capture-MS Homo sapiens
150 HSPA4 3308
Co-fractionation Homo sapiens
151 EIF2B1 1967
Affinity Capture-MS Homo sapiens
152 COX2 4513
Two-hybrid Homo sapiens
153 ARL2 402
Affinity Capture-MS Homo sapiens
154 CDKN1B 1027
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
155 FGF12  
Reconstituted Complex Homo sapiens
156 NFATC2  
Affinity Capture-MS Homo sapiens
157 GRIP1  
Affinity Capture-MS Homo sapiens
158 MAP3K10  
Affinity Capture-Western Homo sapiens
159 GPBP1L1  
Affinity Capture-MS Homo sapiens
160 VASP 7408
Affinity Capture-MS Homo sapiens
161 C6orf222  
Affinity Capture-MS Homo sapiens
162 PSMB2 5690
Co-fractionation Homo sapiens
163 ARPC3 10094
Affinity Capture-MS Homo sapiens
164 USP46 64854
Affinity Capture-MS Homo sapiens
165 TP53BP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
166 SF3B1 23451
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
167 KAT8  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
168 GRB2 2885
Affinity Capture-MS Homo sapiens
169 BAD  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
170 SSFA2 6744
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
171 GSS 2937
Co-fractionation Homo sapiens
172 PDE7A  
Affinity Capture-MS Homo sapiens
173 SSH1  
Affinity Capture-MS Homo sapiens
174 RUVBL2 10856
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
175 FRYL 285527
Affinity Capture-MS Homo sapiens
176 MACF1 23499
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
177 CENPJ 55835
Affinity Capture-MS Homo sapiens
178 POLR3H  
Affinity Capture-MS Homo sapiens
179 IL1B  
Affinity Capture-MS Homo sapiens
180 IRS2 8660
Affinity Capture-MS Homo sapiens
181 ARL8A 127829
Affinity Capture-MS Homo sapiens
182 PIK3R4 30849
Affinity Capture-MS Homo sapiens
183 RCHY1  
Affinity Capture-MS Homo sapiens
184 FAM53B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
185 STK38L 23012
Affinity Capture-MS Homo sapiens
186 TRA2B 6434
Affinity Capture-MS Homo sapiens
187 CGNL1  
Two-hybrid Homo sapiens
188 TRIP11 9321
Affinity Capture-MS Homo sapiens
189 RAB11FIP1 80223
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
190 SSBP1 6742
Co-fractionation Homo sapiens
191 PSMA1 5682
Co-fractionation Homo sapiens
192 DYNC1H1 1778
Affinity Capture-MS Homo sapiens
193 TBK1 29110
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
194 WWP2 11060
Affinity Capture-MS Homo sapiens
195 PDZD11 51248
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
196 CLASP1 23332
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
197 GAPDH 2597
Two-hybrid Homo sapiens
198 PPP1R2 5504
Co-fractionation Homo sapiens
199 HNRNPL 3191
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
200 EIF4B 1975
Affinity Capture-MS Homo sapiens
201 PSMA7 5688
Co-fractionation Homo sapiens
202 GLCCI1 113263
Affinity Capture-MS Homo sapiens
203 ADH1B 125
Affinity Capture-MS Homo sapiens
204 PLEKHA7 144100
Affinity Capture-MS Homo sapiens
205 CUL7 9820
Affinity Capture-MS Homo sapiens
206 SYN1  
Affinity Capture-MS Homo sapiens
207 DENND4A 10260
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
208 MAST1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
209 CDC37 11140
Affinity Capture-MS Homo sapiens
210 SMARCC2 6601
Affinity Capture-MS Homo sapiens
211 PSMD3 5709
Cross-Linking-MS (XL-MS) Homo sapiens
212 FAN1  
Affinity Capture-MS Homo sapiens
213 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
214 TRAPPC2 6399
Affinity Capture-MS Homo sapiens
215 SRGAP1 57522
Affinity Capture-MS Homo sapiens
216 CDK17 5128
Affinity Capture-MS Homo sapiens
217 PRKAA1 5562
Affinity Capture-MS Homo sapiens
218 ABLIM1 3983
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
219 NCBP1 4686
Affinity Capture-MS Homo sapiens
220 SPRTN  
Affinity Capture-MS Homo sapiens
221 LRMP  
Two-hybrid Homo sapiens
222 TSC2 7249
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
223 PAWR 5074
Affinity Capture-MS Homo sapiens
224 PI4KB 5298
Affinity Capture-MS Homo sapiens
225 EXO1  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
226 ARL6IP5 10550
Affinity Capture-MS Homo sapiens
227 RPA2 6118
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
228 VPRBP 9730
Affinity Capture-MS Homo sapiens
229 G3BP1 10146
Affinity Capture-MS Homo sapiens
230 APC  
Affinity Capture-MS Homo sapiens
231 ALDH2 217
Co-fractionation Homo sapiens
232 LIMA1 51474
Affinity Capture-MS Homo sapiens
233 PHLDB1 23187
Affinity Capture-MS Homo sapiens
234 HSP90AB1 3326
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
235 GRB10 2887
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
236 GRPEL1 80273
Co-fractionation Homo sapiens
237 SRSF2 6427
Affinity Capture-MS Homo sapiens
238 SYDE2  
Affinity Capture-MS Homo sapiens
239 COPA 1314
Affinity Capture-MS Homo sapiens
240 KIF1B 23095
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
241 ARL8B 55207
Affinity Capture-MS Homo sapiens
242 RPS3 6188
Affinity Capture-MS Homo sapiens
243 REEP3 221035
Affinity Capture-MS Homo sapiens
244 GRHPR 9380
Affinity Capture-MS Homo sapiens
245 KIF13B 23303
Affinity Capture-MS Homo sapiens
246 WTAP 9589
Affinity Capture-MS Homo sapiens
247 ARL6IP6  
Affinity Capture-MS Homo sapiens
248 PGK1 5230
Co-fractionation Homo sapiens
249 TNK1  
Affinity Capture-MS Homo sapiens
250 REM1  
Far Western Homo sapiens
251 JAKMIP1 152789
Affinity Capture-MS Homo sapiens
252 RBM3 5935
Affinity Capture-MS Homo sapiens
253 HSP90AA1 3320
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
254 COQ9  
Co-fractionation Homo sapiens
255 SPIN1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
256 PRC1 9055
Two-hybrid Homo sapiens
257 NPM1 4869
Affinity Capture-MS Homo sapiens
258 SRRM2 23524
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
259 MAPK14 1432
Co-fractionation Homo sapiens
260 OBSL1 23363
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
261 MGA  
Affinity Capture-MS Homo sapiens
262 SYNJ2 8871
Affinity Capture-MS Homo sapiens
263 STIP1 10963
Cross-Linking-MS (XL-MS) Homo sapiens
264 RACGAP1 29127
Affinity Capture-MS Homo sapiens
265 VAPB 9217
Affinity Capture-MS Homo sapiens
266 PTPN14 5784
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
267 YWHAH 7533
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
268 VCAM1 7412
Affinity Capture-MS Homo sapiens
269 DDX6 1656
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
270 FGD6  
Affinity Capture-MS Homo sapiens
271 SMAGP  
Reconstituted Complex Homo sapiens
272 CD28  
Affinity Capture-MS Homo sapiens
273 CUL1 8454
Affinity Capture-MS Homo sapiens
274 PLEKHA2 59339
Affinity Capture-MS Homo sapiens
275 FASTKD2  
Affinity Capture-MS Homo sapiens
276 CEP85L  
Affinity Capture-MS Homo sapiens
277 TBC1D1 23216
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
278 YWHAB 7529
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
279 PTPN3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
280 AGAP1  
Affinity Capture-MS Homo sapiens
281 LRCH1 23143
Affinity Capture-MS Homo sapiens
282 ACTA2 59
Co-fractionation Homo sapiens
283 PHLDB2 90102
Affinity Capture-MS Homo sapiens
284 NOLC1 9221
Affinity Capture-MS Homo sapiens
285 HIST1H4A 8359
Affinity Capture-Western Homo sapiens
286 TRIM26 7726
Affinity Capture-MS Homo sapiens
287 ZNF750  
Cross-Linking-MS (XL-MS) Homo sapiens
288 ISCU 23479
Affinity Capture-MS Homo sapiens
289 RPL4 6124
Affinity Capture-MS Homo sapiens
290 KLC1 3831
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
291 TET2  
Affinity Capture-MS Homo sapiens
292 TAB3 257397
Affinity Capture-MS Homo sapiens
293 MSX2  
Affinity Capture-MS Homo sapiens
294 CDR2L  
Affinity Capture-MS Homo sapiens
295 KLC4 89953
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
296 CBL 867
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
297 EFHD2 79180
Affinity Capture-MS Homo sapiens
298 TUBB2B 347733
Affinity Capture-MS Homo sapiens
299 HDX  
Affinity Capture-MS Homo sapiens
300 SNRPD1 6632
Co-fractionation Homo sapiens
301 NELFE 7936
Affinity Capture-MS Homo sapiens
302 CAMSAP3  
Affinity Capture-MS Homo sapiens
303 SIPA1L2  
Affinity Capture-MS Homo sapiens
304 DCAF7 10238
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
305 RIN1 9610
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
306 ACAT2 39
Co-fractionation Homo sapiens
307 PPP2CA 5515
Affinity Capture-MS Homo sapiens
308 SCAF11  
Affinity Capture-MS Homo sapiens
309 TMEM102  
Affinity Capture-MS Homo sapiens
310 TESPA1  
Affinity Capture-MS Homo sapiens
311 TMEM11 8834
Affinity Capture-MS Homo sapiens
312 PHACTR4 65979
Affinity Capture-MS Homo sapiens
313 RPLP0 6175
Affinity Capture-MS Homo sapiens
314 GAREM  
Affinity Capture-MS Homo sapiens
315 Ksr1  
Affinity Capture-MS Mus musculus
316 CYLD  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
317 TICRR 90381
Affinity Capture-MS Homo sapiens
318 NADK 65220
Affinity Capture-MS Homo sapiens
319 MARK1 4139
Affinity Capture-MS Homo sapiens
320 ALDH7A1 501
Co-fractionation Homo sapiens
321 PTOV1  
Affinity Capture-MS Homo sapiens
322 PER2  
Proximity Label-MS Homo sapiens
323 SYN2 6854
Two-hybrid Homo sapiens
324 TUBB 203068
Affinity Capture-MS Homo sapiens
325 SFN 2810
Co-fractionation Homo sapiens
326 RGS12 6002
Affinity Capture-MS Homo sapiens
327 PANK2 80025
Affinity Capture-MS Homo sapiens
328 ALS2  
Affinity Capture-MS Homo sapiens
329 XPO1 7514
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
330 R3HDM1  
Affinity Capture-MS Homo sapiens
331 RC3H2  
Affinity Capture-MS Homo sapiens
332 CNTLN 54875
Affinity Capture-MS Homo sapiens
333 AKAP9 10142
Two-hybrid Homo sapiens
334 DAB2IP 153090
Affinity Capture-MS Homo sapiens
335 RICTOR 253260
Affinity Capture-MS Homo sapiens
336 TUBB4B 10383
Affinity Capture-MS Homo sapiens
337 USP54 159195
Affinity Capture-MS Homo sapiens
338 AKAP13 11214
Affinity Capture-MS Homo sapiens
339 Mdm4  
Reconstituted Complex Mus musculus
340 RPTOR 57521
Affinity Capture-MS Homo sapiens
341 KIAA0930  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
342 FTH1 2495
Two-hybrid Homo sapiens
343 SNF8 11267
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
344 RIPK4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
345 SAMD4B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
346 G6PD 2539
Co-fractionation Homo sapiens
347 TBC1D7  
Affinity Capture-MS Homo sapiens
348 ACTR6  
Co-fractionation Homo sapiens
349 CDK2 1017
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
350 CEP250 11190
Affinity Capture-MS Homo sapiens
351 R3HDM2  
Affinity Capture-MS Homo sapiens
352 RAPGEF2 9693
Affinity Capture-MS Homo sapiens
353 MYC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
354 HMGB3 3149
Cross-Linking-MS (XL-MS) Homo sapiens
355 FAM64A 54478
Reconstituted Complex Homo sapiens
356 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
357 TMOD3 29766
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
358 PTPDC1  
Affinity Capture-MS Homo sapiens
359 EEF1A2 1917
Affinity Capture-MS Homo sapiens
360 CSNK1A1 1452
Affinity Capture-MS Homo sapiens
361 DDB1 1642
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
362 RCN2 5955
Affinity Capture-MS Homo sapiens
363 DDRGK1 65992
Affinity Capture-MS Homo sapiens
364 Yap1  
Affinity Capture-MS Mus musculus
365 ISOC1 51015
Co-fractionation Homo sapiens
366 PCM1 5108
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
367 ATP6V0B 533
Reconstituted Complex Homo sapiens
368 CCDC88A 55704
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
369 MPRIP 23164
Affinity Capture-MS Homo sapiens
370 DOCK11 139818
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
371 NELFB 25920
Affinity Capture-MS Homo sapiens
372 OSBPL8 114882
Affinity Capture-MS Homo sapiens
373 TAF4 6874
Affinity Capture-MS Homo sapiens
374 SOD1 6647
Affinity Capture-MS Homo sapiens
375 FRMD6 122786
Affinity Capture-MS Homo sapiens
376 HUWE1 10075
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
377 IQSEC2 23096
Affinity Capture-MS Homo sapiens
378 TCF25 22980
Affinity Capture-MS Homo sapiens
379 PA2G4 5036
Affinity Capture-MS Homo sapiens
380 PRICKLE3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
381 MARK3 4140
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
382 RBM14 10432
Two-hybrid Homo sapiens
383 RNF43  
Proximity Label-MS Homo sapiens
384 SH3RF3  
Affinity Capture-MS Homo sapiens
385 MAP2K2 5605
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
386 GIGYF2 26058
Affinity Capture-MS Homo sapiens
387 UHRF1BP1L 23074
Affinity Capture-MS Homo sapiens
388 UBR2 23304
Affinity Capture-MS Homo sapiens
389 PRRC2A 7916
Affinity Capture-MS Homo sapiens
390 PLEKHA5 54477
Affinity Capture-MS Homo sapiens
391 TP53 7157
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
392 MTMR3  
Affinity Capture-MS Homo sapiens
393 DENND1A 57706
Affinity Capture-MS Homo sapiens
394 SH2D3A  
Affinity Capture-MS Homo sapiens
395 HDAC6 10013
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
396 SPIRE1 56907
Affinity Capture-MS Homo sapiens
397 SIPA1L3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
398 COL6A5  
Cross-Linking-MS (XL-MS) Homo sapiens
399 DEPDC5  
Affinity Capture-MS Homo sapiens
400 Numb  
Affinity Capture-MS Mus musculus
401 ATG101  
Affinity Capture-MS Homo sapiens
402 CDC25C  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
403 STK26 51765
Co-fractionation Homo sapiens
404 SHMT2 6472
Co-fractionation Homo sapiens
405 MAP7D1 55700
Affinity Capture-MS Homo sapiens
406 MAP2K1 5604
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
407 IARS2 55699
Co-fractionation Homo sapiens
408 MCFD2 90411
Co-fractionation Homo sapiens
409 DDX39A 10212
Co-fractionation Homo sapiens
410 OSBPL3 26031
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
411 PPM1B 5495
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
412 REEP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
413 GAPVD1 26130
Affinity Capture-MS Homo sapiens
414 IL7R  
Protein-RNA Homo sapiens
415 BRD1 23774
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
416 C1QBP 708
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
417 ARID3B  
Affinity Capture-MS Homo sapiens
418 KRAS 3845
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
419 PNLIP  
Two-hybrid Homo sapiens
420 MAST3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
421 BCAR1 9564
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
422 PRMT1 3276
Affinity Capture-MS Homo sapiens
423 SH3PXD2A 9644
Affinity Capture-MS Homo sapiens
424 JAK1 3716
Affinity Capture-MS Homo sapiens
425 GUCA1B  
Affinity Capture-MS Homo sapiens
426 PFKFB4 5210
Affinity Capture-MS Homo sapiens
427 MIS12  
Affinity Capture-MS Homo sapiens
428 NAF1  
Reconstituted Complex Homo sapiens
429 HNRNPC 3183
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
430 DLG5 9231
Affinity Capture-MS Homo sapiens
431 USP43  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
432 EEF1G 1937
Affinity Capture-MS Homo sapiens
433 KSR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
434 CENPE 1062
Co-fractionation Homo sapiens
435 ZBTB21  
Affinity Capture-MS Homo sapiens
436 GRAP2 9402
Two-hybrid Homo sapiens
437 PTMA 5757
Co-fractionation Homo sapiens
438 SNX33 257364
Affinity Capture-MS Homo sapiens
439 ACTR2 10097
Affinity Capture-MS Homo sapiens
440 C8orf59  
Reconstituted Complex Homo sapiens
441 PARD3 56288
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
442 RARRES3  
Affinity Capture-Western Homo sapiens
443 PAK2 5062
Co-fractionation Homo sapiens
444 MICALL1 85377
Affinity Capture-MS Homo sapiens
445 ARL14EP  
Affinity Capture-MS Homo sapiens
446 SSB 6741
Co-fractionation Homo sapiens
447 CYSLTR2  
Two-hybrid Homo sapiens
448 CAMSAP2  
Affinity Capture-MS Homo sapiens
449 CBY1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
450 CRTC1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
451 ANKS1A 23294
Affinity Capture-MS Homo sapiens
452 CAPZB 832
Affinity Capture-MS Homo sapiens
453 MLLT4 4301
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
454 FAM13B  
Two-hybrid Homo sapiens
455 PAK4 10298
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
456 PFKFB2 5208
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
457 MCM2 4171
Affinity Capture-MS Homo sapiens
458 SOGA1 140710
Affinity Capture-MS Homo sapiens
459 KLC2 64837
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
460 NUMBL 9253
Affinity Capture-MS Homo sapiens
461 ZNF638 27332
Affinity Capture-MS Homo sapiens
462 RAB3IP  
Affinity Capture-MS Homo sapiens
463 LPIN2  
Affinity Capture-MS Homo sapiens
464 ZNF839  
Two-hybrid Homo sapiens
465 PTPN4  
Affinity Capture-MS Homo sapiens
466 IQGAP1 8826
Co-fractionation Homo sapiens
467 CLIP1 6249
Affinity Capture-MS Homo sapiens
468 MCTS1 28985
Co-fractionation Homo sapiens
469 HMHA1 23526
Affinity Capture-MS Homo sapiens
470 FAM83G  
Affinity Capture-MS Homo sapiens
471 MAP3K3 4215
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
472 TFEB  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
473 IRS4 8471
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
474 TNFAIP8 25816
Co-fractionation Homo sapiens
475 CEP170 9859
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
476 MACC1 346389
Affinity Capture-MS Homo sapiens
477 SAMD4A 23034
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
478 ITGA4 3676
Affinity Capture-MS Homo sapiens
479 STXBP3 6814
Cross-Linking-MS (XL-MS) Homo sapiens
480 ATG16L1 55054
Affinity Capture-MS Homo sapiens
481 AGXT  
Affinity Capture-MS Homo sapiens
482 CALR 811
Co-fractionation Homo sapiens
483 CEP131 22994
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
484 VAPA 9218
Affinity Capture-MS Homo sapiens
485 WASF3 10810
Affinity Capture-MS Homo sapiens
486 YAF2  
Affinity Capture-MS Homo sapiens
487 PABPC4 8761
Affinity Capture-MS Homo sapiens
488 APPL1 26060
Affinity Capture-MS Homo sapiens
489 HSPA8 3312
Affinity Capture-MS Homo sapiens
490 MELK  
Affinity Capture-MS Homo sapiens
491 SCPEP1 59342
Co-fractionation Homo sapiens
492 EPB41L3 23136
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
493 DLD 1738
Affinity Capture-MS Homo sapiens
494 ATP5A1 498
Affinity Capture-MS Homo sapiens
495 KIAA1211  
Affinity Capture-MS Homo sapiens
496 DIABLO 56616
Co-fractionation Homo sapiens
497 ANKRD34A  
Affinity Capture-MS Homo sapiens
498 REEP4  
Affinity Capture-MS Homo sapiens
499 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
500 TTLL7  
Affinity Capture-MS Homo sapiens
501 IGF1R 3480
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
502 COPE 11316
Affinity Capture-MS Homo sapiens
503 CEP55 55165
Affinity Capture-MS Homo sapiens
504 RABEP1 9135
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
505 CLNS1A 1207
Affinity Capture-MS Homo sapiens
506 MEX3C 51320
Affinity Capture-MS Homo sapiens
507 TUBA1A 7846
Affinity Capture-MS Homo sapiens
508 MCM10 55388
Reconstituted Complex Homo sapiens
509 CBX3 11335
Co-fractionation Homo sapiens
510 USP8 9101
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
511 MAPT  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
512 C5orf30  
Affinity Capture-MS Homo sapiens
513 BTF3 689
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
514 IGHG1 3500
Affinity Capture-MS Homo sapiens
515 ANKHD1-EIF4EBP3  
Two-hybrid Homo sapiens
516 NTRK1 4914
Affinity Capture-MS Homo sapiens
517 U2AF2 11338
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
518 DCP1A 55802
Affinity Capture-MS Homo sapiens
519 DNAJA1 3301
Affinity Capture-MS Homo sapiens
520 SMTNL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
521 ACTB 60
Affinity Capture-MS Homo sapiens
522 DHX9 1660
Affinity Capture-MS Homo sapiens
523 PDE7B  
Affinity Capture-MS Homo sapiens
524 ENY2 56943
Cross-Linking-MS (XL-MS) Homo sapiens
525 DOK3 79930
Affinity Capture-MS Homo sapiens
526 PIK3C2A 5286
Affinity Capture-MS Homo sapiens
527 FAM124A  
Affinity Capture-MS Homo sapiens
528 HNRNPA3 220988
Affinity Capture-MS Homo sapiens
529 HDAC5 10014
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
530 DNM1L 10059
Affinity Capture-MS Homo sapiens
531 RMDN3 55177
Proximity Label-MS Homo sapiens
532 IPO9 55705
Affinity Capture-MS Homo sapiens
533 RBM10  
Affinity Capture-MS Homo sapiens
534 LARP1 23367
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
535 ACTN4 81
Affinity Capture-MS Homo sapiens
536 DISC1 27185
Two-hybrid Homo sapiens
537 ECH1 1891
Co-fractionation Homo sapiens
538 ANKZF1 55139
Reconstituted Complex Homo sapiens
539 SF3B2 10992
Affinity Capture-MS Homo sapiens
540 ZAK 51776
Affinity Capture-MS Homo sapiens
541 DENND4C 55667
Affinity Capture-MS Homo sapiens
542 SIK3 23387
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
543 MYCBP2 23077
Affinity Capture-MS Homo sapiens
544 CDC73  
Affinity Capture-MS Homo sapiens
545 LBR 3930
Affinity Capture-MS Homo sapiens
546 SHROOM3 57619
Affinity Capture-MS Homo sapiens
547 STAC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
548 TBC1D22B  
Affinity Capture-MS Homo sapiens
549 NGFRAP1  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
550 FERMT2 10979
Co-fractionation Homo sapiens
551 TAB1 10454
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
552 INPP5E 56623
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
553 HDAC9  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
554 HIST2H4B 554313
Affinity Capture-MS Homo sapiens
555 STIM1 6786
Affinity Capture-MS Homo sapiens
556 PRKD1 5587
Affinity Capture-MS Homo sapiens
557 FBXO6 26270
Affinity Capture-MS Homo sapiens
558 MDM4  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
559 UBE2R2 54926
Co-fractionation Homo sapiens
560 BAIAP2L1 55971
Affinity Capture-MS Homo sapiens
561 DMTN  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
562 CAND1 55832
Affinity Capture-MS Homo sapiens
563 NT5C2 22978
Affinity Capture-MS Homo sapiens
564 CDC42BPA 8476
Affinity Capture-MS Homo sapiens
565 SPTAN1 6709
Cross-Linking-MS (XL-MS) Homo sapiens
566 FAM13A 10144
Affinity Capture-MS Homo sapiens
567 PTPN13 5783
Affinity Capture-MS Homo sapiens
568 KSR2  
Affinity Capture-MS Homo sapiens
569 SGK223  
Affinity Capture-MS Homo sapiens
570 SAV1  
Affinity Capture-MS Homo sapiens
571 MTOR 2475
Affinity Capture-MS Homo sapiens
572 RAB11B 9230
Affinity Capture-MS Homo sapiens
573 AFAP1L1 134265
Affinity Capture-MS Homo sapiens
574 EPB41 2035
Affinity Capture-MS Homo sapiens
575 FAM60A  
Affinity Capture-MS Homo sapiens
576 SH3D19 152503
Affinity Capture-MS Homo sapiens
577 CGN  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
578 PPP6C 5537
Affinity Capture-MS Homo sapiens
579 LTBP1 4052
Affinity Capture-MS Homo sapiens
580 SIK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
581 ARAF 369
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
582 ULK1  
Affinity Capture-MS Homo sapiens
583 NEDD4L 23327
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
584 ATIC 471
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
585 PROSC 11212
Co-fractionation Homo sapiens
586 MPHOSPH9  
Affinity Capture-MS Homo sapiens
587 ARHGEF7 8874
Affinity Capture-MS Homo sapiens
588 TUBB2A 7280
Co-fractionation Homo sapiens
589 DEPDC1B 55789
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
590 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
591 FBXW11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
592 FOXO3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
593 SHCBP1 79801
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
594 SLC25A6 293
Affinity Capture-MS Homo sapiens
595 KIAA1598 57698
Affinity Capture-MS Homo sapiens
596 JUP 3728
Affinity Capture-MS Homo sapiens
597 MTBP  
Affinity Capture-MS Homo sapiens
598 RPL6 6128
Affinity Capture-MS Homo sapiens
599 TTC28 23331
Affinity Capture-MS Homo sapiens
600 LSR 51599
Affinity Capture-MS Homo sapiens
601 ALDH1B1 219
Co-fractionation Homo sapiens
602 HNRNPA1 3178
Affinity Capture-Western Homo sapiens
603 MS4A1 931
Affinity Capture-MS Homo sapiens
604 ABL1 25
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
605 HSPB1 3315
Two-hybrid Homo sapiens
606 CAP2 10486
Two-hybrid Homo sapiens
607 ASNS 440
Co-fractionation Homo sapiens
608 RBM15 64783
Affinity Capture-MS Homo sapiens
609 REEP2  
Affinity Capture-MS Homo sapiens
610 EDC3 80153
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
611 CFAP43 80217
Affinity Capture-MS Homo sapiens
612 PAFAH2 5051
Co-fractionation Homo sapiens
613 GAB2 9846
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
614 PPFIBP2 8495
Affinity Capture-MS Homo sapiens
615 TOP2A 7153
Affinity Capture-Western Homo sapiens
616 UFL1 23376
Affinity Capture-MS Homo sapiens
617 PAFAH1B2 5049
Co-fractionation Homo sapiens
618 DYNC1LI1 51143
Affinity Capture-MS Homo sapiens
619 CCNY 219771
Affinity Capture-MS Homo sapiens
620 MAPK7  
Two-hybrid Homo sapiens
621 TESK2  
Affinity Capture-MS Homo sapiens
622 CDK13 8621
Affinity Capture-MS Homo sapiens
623 API5 8539
Affinity Capture-MS Homo sapiens
624 ST5 6764
Affinity Capture-MS Homo sapiens
625 AARS2  
Co-fractionation Homo sapiens
626 LRRK2 120892
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
627 ADH4  
Affinity Capture-MS Homo sapiens
628 PRDX6 9588
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Reconstituted Complex Homo sapiens
629 LCP2 3937
Reconstituted Complex Homo sapiens
630 SERBP1 26135
Affinity Capture-MS Homo sapiens
631 C21orf2  
Affinity Capture-MS Homo sapiens
632 CHST11 50515
Reconstituted Complex Homo sapiens
633 RC3H1 149041
Affinity Capture-MS Homo sapiens
634 ATXN3 4287
Affinity Capture-MS Homo sapiens
635 TIMM44 10469
Co-fractionation Homo sapiens
636 CDKN2A 1029
Affinity Capture-MS Homo sapiens
637 EIF5 1983
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
638 BCR 613
Affinity Capture-MS Homo sapiens
639 CAPN2 824
Co-fractionation Homo sapiens
640 UBE2H 7328
Affinity Capture-MS Homo sapiens
641 INSIG1  
Affinity Capture-MS Homo sapiens
642 SLFN11 91607
Proximity Label-MS Homo sapiens
643 TNFAIP3 7128
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
644 Usp8  
Affinity Capture-MS Mus musculus
645 ARHGAP21 57584
Affinity Capture-MS Homo sapiens
646 SLC4A7 9497
Affinity Capture-MS Homo sapiens
647 ENKD1  
Two-hybrid Homo sapiens
648 PARD3B 117583
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
649 CRTC2 200186
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
650 TWF2 11344
Co-fractionation Homo sapiens
651 CDK11B 984
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
652 POT1  
Two-hybrid Homo sapiens
653 OGFOD1  
Co-fractionation Homo sapiens
654 DCP1B  
Affinity Capture-MS Homo sapiens
655 PPIE 10450
Affinity Capture-MS Homo sapiens
656 NKD2 85409
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
657 SPATA13  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
658 KPNB1 3837
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
659 MATR3 9782
Affinity Capture-MS Homo sapiens
660 PRPSAP2 5636
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
661 CALM1 801
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
662 TROVE2 6738
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
663 NAV2  
Affinity Capture-MS Homo sapiens
664 EPB41L1 2036
Affinity Capture-MS Homo sapiens
665 ILF2 3608
Affinity Capture-MS Homo sapiens
666 FAM126A 84668
Affinity Capture-MS Homo sapiens
667 KIAA1429 25962
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
668 RALGAPB 57148
Affinity Capture-MS Homo sapiens
669 PKP2 5318
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
670 CCR9  
Two-hybrid Homo sapiens
671 PPP1R12A 4659
Affinity Capture-MS Homo sapiens
672 MARK2 2011
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
673 TBCB 1155
Co-fractionation Homo sapiens
674 HLA-DRB3 3125
Affinity Capture-MS Homo sapiens
675 PLEKHG5 57449
Affinity Capture-MS Homo sapiens
Affinity Capture-MS