Gene description for HNRNPLL
Gene name heterogeneous nuclear ribonucleoprotein L-like
Gene symbol HNRNPLL
Other names/aliases HNRPLL
SRRF
Species Homo sapiens
 Database cross references - HNRNPLL
ExoCarta ExoCarta_92906
Vesiclepedia VP_92906
Entrez Gene 92906
HGNC 25127
MIM 611208
UniProt Q8WVV9  
 HNRNPLL identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for HNRNPLL
Molecular Function
    RNA binding GO:0003723 HDA
    mRNA binding GO:0003729 IBA
    mRNA binding GO:0003729 IDA
    protein binding GO:0005515 IPI
Biological Process
    mRNA processing GO:0006397 IEA
    positive regulation of RNA splicing GO:0033120 IDA
    regulation of RNA splicing GO:0043484 IBA
Subcellular Localization
    nucleus GO:0005634 IBA
    membrane GO:0016020 HDA
    synapse GO:0045202 IEA
    ribonucleoprotein complex GO:1990904 IEA
 Experiment description of studies that identified HNRNPLL in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for HNRNPLL
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 PLCD4  
Affinity Capture-MS Homo sapiens
3 HOMER3 9454
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 RPL26L1 51121
Affinity Capture-MS Homo sapiens
5 HOOK1  
Two-hybrid Homo sapiens
6 RBPMS 11030
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
7 NUDT10  
Affinity Capture-MS Homo sapiens
8 PAXIP1  
Two-hybrid Homo sapiens
9 CCNB2  
Co-fractionation Homo sapiens
10 SAMD11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 H2AFJ 55766
Affinity Capture-MS Homo sapiens
12 QKI 9444
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 EPB41L5 57669
Affinity Capture-MS Homo sapiens
14 MDFI  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
15 DAB1 1600
Two-hybrid Homo sapiens
16 IL36RN  
Affinity Capture-MS Homo sapiens
17 CALM1 801
Affinity Capture-MS Homo sapiens
18 ANKRD39  
Affinity Capture-MS Homo sapiens
19 RHOXF2  
Two-hybrid Homo sapiens
20 PCBP3 54039
Two-hybrid Homo sapiens
21 APEX1 328
Affinity Capture-RNA Homo sapiens
22 EIF4ENIF1 56478
Two-hybrid Homo sapiens
23 HDAC3 8841
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 WDR76  
Affinity Capture-MS Homo sapiens
25 ZFHX4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 DENND2D  
Two-hybrid Homo sapiens
27 RBM3 5935
Two-hybrid Homo sapiens
28 HELZ 9931
Affinity Capture-MS Homo sapiens
29 Htatsf1  
Two-hybrid Mus musculus
30 SPANXN4  
Affinity Capture-MS Homo sapiens
31 GDI1 2664
Affinity Capture-MS Homo sapiens
32 TWISTNB  
Two-hybrid Homo sapiens
33 ANOS1 3730
Affinity Capture-MS Homo sapiens
34 Mrps31  
Two-hybrid Mus musculus
35 Hnrnpk 15387
Two-hybrid Mus musculus
36 PDIA6 10130
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 MECP2 4204
Affinity Capture-MS Homo sapiens
38 JMJD4  
Affinity Capture-MS Homo sapiens
39 KIF14 9928
Affinity Capture-MS Homo sapiens
40 KIAA1217 56243
Co-fractionation Homo sapiens
41 PRPF6 24148
Two-hybrid Homo sapiens
42 ZKSCAN8  
Affinity Capture-MS Homo sapiens
43 USP10 9100
Two-hybrid Homo sapiens
44 ARL2BP 23568
Affinity Capture-MS Homo sapiens
45 PARK2  
Affinity Capture-MS Homo sapiens
46 CCAR2 57805
Affinity Capture-MS Homo sapiens
47 MCM9 254394
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 ZBTB48  
Affinity Capture-MS Homo sapiens
49 UBE2I 7329
Two-hybrid Homo sapiens
50 CCNB1 891
Co-fractionation Homo sapiens
51 UBR5 51366
Affinity Capture-MS Homo sapiens
52 BARD1 580
Two-hybrid Homo sapiens
53 NTRK1 4914
Affinity Capture-MS Homo sapiens
54 GPSM3  
Affinity Capture-MS Homo sapiens
55 APBA1  
Affinity Capture-MS Homo sapiens
56 BOLL  
Two-hybrid Homo sapiens
57 MBNL2 10150
Affinity Capture-MS Homo sapiens
58 HDAC5 10014
Affinity Capture-MS Homo sapiens
59 CEBPA  
Protein-peptide Homo sapiens
60 RAVER2  
Affinity Capture-MS Homo sapiens
61 ATXN1 6310
Two-hybrid Homo sapiens
62 SRSF11 9295
Two-hybrid Homo sapiens
63 ANGEL2 90806
Affinity Capture-MS Homo sapiens
64 RNF40 9810
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
65 PSMA3 5684
Affinity Capture-MS Homo sapiens
66 RNF181  
Affinity Capture-MS Homo sapiens
67 WDR33 55339
Affinity Capture-MS Homo sapiens
68 CD6 923
Affinity Capture-MS Homo sapiens
69 SETD2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 PHYHD1 254295
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 FAM208A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 VHL  
Affinity Capture-MS Homo sapiens
73 THAP1  
Two-hybrid Homo sapiens
74 PPHLN1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
75 PJA1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
76 DGKZ  
Affinity Capture-MS Homo sapiens
77 PCBP1 5093
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
78 MREG  
Two-hybrid Homo sapiens
79 FAM208B 54906
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 N4BP2L2 10443
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 ESRP2 80004
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
82 DDRGK1 65992
Affinity Capture-MS Homo sapiens
83 FAM188A 80013
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 Tia1  
Two-hybrid Mus musculus
85 RCN1 5954
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
86 TBX3 6926
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
87 CLPP 8192
Proximity Label-MS Homo sapiens
88 EIF1AD 84285
Affinity Capture-MS Homo sapiens
89 SURF6  
Affinity Capture-MS Homo sapiens
90 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
91 BCAS2 10286
Two-hybrid Homo sapiens
92 MTPN 136319
Affinity Capture-MS Homo sapiens
93 CCDC85A  
Affinity Capture-MS Homo sapiens
94 SCYL3 57147
Affinity Capture-MS Homo sapiens
95 Ube2i  
Two-hybrid Mus musculus
96 SNRPA 6626
Two-hybrid Homo sapiens
97 PTBP1 5725
Two-hybrid Homo sapiens
98 C1orf35  
Affinity Capture-MS Homo sapiens
99 CNOT3 4849
Co-fractionation Homo sapiens
100 HNRNPK 3190
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
101 RAVER1 125950
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
102 UFL1 23376
Affinity Capture-MS Homo sapiens
103 GSTM3 2947
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
104 HDGFRP2 84717
Affinity Capture-MS Homo sapiens
105 MINPP1 9562
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
106 HNRNPL 3191
Affinity Capture-MS Homo sapiens
107 NCOR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
108 HNRNPLL 92906
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
109 CIT 11113
Affinity Capture-MS Homo sapiens
110 RPL28 6158
Affinity Capture-MS Homo sapiens
111 SNW1 22938
Affinity Capture-MS Homo sapiens
112 CDC5L 988
Affinity Capture-MS Homo sapiens
113 TMCC2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
114 PAF1 54623
Affinity Capture-MS Homo sapiens
115 LIMK2 3985
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
116 ZNF467  
Affinity Capture-MS Homo sapiens
117 NSUN5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
118 PAGE1  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which HNRNPLL is involved
No pathways found





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