Gene description for XRN1
Gene name	5'-3' exoribonuclease 1
Gene symbol	XRN1
Other names/aliases	SEP1
Species	Homo sapiens
Database cross references - XRN1
ExoCarta	ExoCarta_54464
Entrez Gene	54464
HGNC	30654
MIM	607994
UniProt	Q8IZH2
XRN1 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for XRN1

Molecular Function     5'-3' exonuclease activity GO:0008409 IEA     protein binding GO:0005515 IPI     DNA binding GO:0003677 IEA     poly(A) RNA binding GO:0044822 IDA Biological Process     nucleic acid phosphodiester bond hydrolysis GO:0090305 IEA     histone mRNA catabolic process GO:0071044 IMP     exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay GO:0043928 TAS     rRNA catabolic process GO:0016075 IMP     nuclear-transcribed mRNA catabolic process GO:0000956 IMP     nuclear mRNA surveillance GO:0071028 IMP     gene expression GO:0010467 TAS     nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 TAS Subcellular Localization     membrane GO:0016020 IDA     nucleus GO:0005634 IMP     cytosol GO:0005829 TAS     intermediate filament cytoskeleton GO:0045111 IDA     plasma membrane GO:0005886 IDA     cytoplasmic mRNA processing body GO:0000932 IEA     Golgi apparatus GO:0005794 IDA     cytoplasm GO:0005737 IDA