Gene description for SLC9A1
Gene name	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
Gene symbol	SLC9A1
Other names/aliases	APNH LIKNS NHE-1 NHE1 PPP1R143
Species	Homo sapiens
Database cross references - SLC9A1
ExoCarta	ExoCarta_6548
Entrez Gene	6548
HGNC	11071
MIM	107310
UniProt	P19634
SLC9A1 identified in exosomes derived from the following tissue/cell type
Hepatocytes	26054723
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927
Platelets	25332113
Platelets	25332113
Platelets	25332113
Saliva	19199708

Gene ontology annotations for SLC9A1

Molecular Function     calcium-dependent protein binding GO:0048306 IDA     protein phosphatase 2B binding GO:0030346 IPI     solute:proton antiporter activity GO:0015299 TAS     sodium:proton antiporter activity GO:0015385 ISS     sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential GO:0086040 TAS     phosphatidylinositol-4,5-bisphosphate binding GO:0005546 TAS     protein binding, bridging GO:0030674 TAS     protein complex scaffold GO:0032947 TAS     calmodulin binding GO:0005516 IEA     protein binding GO:0005515 IPI Biological Process     cell migration GO:0016477 TAS     protein oligomerization GO:0051259 ISS     cardiac muscle cell contraction GO:0086003 IEA     positive regulation of transcription from RNA polymerase II promoter GO:0045944 IDA     hydrogen ion transmembrane transport GO:1902600 IDA     regulation of stress fiber assembly GO:0051492 TAS     cardiac muscle cell differentiation GO:0055007 IEA     positive regulation of cell growth GO:0030307 IEA     regulation of sensory perception of pain GO:0051930 IEA     regulation of intracellular pH GO:0051453 IDA     regulation of cardiac muscle contraction by calcium ion signaling GO:0010882 IMP     cellular sodium ion homeostasis GO:0006883 IDA     small molecule metabolic process GO:0044281 TAS     positive regulation of NFAT protein import into nucleus GO:0051533 IDA     negative regulation of apoptotic process GO:0043066 IEA     maintenance of cell polarity GO:0030011 TAS     carbohydrate metabolic process GO:0005975 TAS     positive regulation of the force of heart contraction GO:0098735 IMP     regulation of focal adhesion assembly GO:0051893 TAS     cellular response to antibiotic GO:0071236 IEA     positive regulation of mitochondrial membrane permeability GO:0035794 IEA     cell growth GO:0016049 IEA     hyaluronan catabolic process GO:0030214 TAS     regulation of pH GO:0006885 TAS     hyaluronan metabolic process GO:0030212 TAS     transmembrane transport GO:0055085 TAS     positive regulation of cardiac muscle hypertrophy GO:0010613 IMP     glycosaminoglycan metabolic process GO:0030203 TAS     ion transport GO:0006811 TAS     positive regulation of calcineurin-NFAT signaling cascade GO:0070886 IDA     response to drug GO:0042493 IEA     sodium ion import across plasma membrane GO:0098719 IDA     cellular response to electrical stimulus GO:0071257 IEA     cellular response to acidic pH GO:0071468 ISS     sodium ion export GO:0071436 ISS     cellular response to insulin stimulus GO:0032869 IEA     neuron death GO:0070997 IEA     regulation of the force of heart contraction by cardiac conduction GO:0086092 IMP     response to acidic pH GO:0010447 IDA     positive regulation of action potential GO:0045760 IEA     response to muscle stretch GO:0035994 IMP     cellular response to epinephrine stimulus GO:0071872 IMP     positive regulation of calcium:sodium antiporter activity GO:1903281 IMP     cellular response to mechanical stimulus GO:0071260 TAS     regulation of cardiac muscle cell membrane potential GO:0086036 TAS     cellular response to hypoxia GO:0071456 IEA Subcellular Localization     cell surface GO:0009986 IEA     cation-transporting ATPase complex GO:0090533 IDA     nucleoplasm GO:0005654 IDA     integral component of membrane GO:0016021 TAS     perinuclear region of cytoplasm GO:0048471 IEA     extracellular exosome GO:0070062 IDA     apical plasma membrane GO:0016324 IEA     intercalated disc GO:0014704 IEA     plasma membrane GO:0005886 TAS     membrane raft GO:0045121 IDA     mitochondrion GO:0005739 IEA     endoplasmic reticulum GO:0005783 ISS     focal adhesion GO:0005925 IDA     lamellipodium GO:0030027 TAS     integral component of plasma membrane GO:0005887 IDA     cytoplasm GO:0005737 IDA     endoplasmic reticulum membrane GO:0005789 IEA     T-tubule GO:0030315 IEA     basolateral plasma membrane GO:0016323 IEA