Gene description for RBM8A
Gene name RNA binding motif protein 8A
Gene symbol RBM8A
Other names/aliases BOV-1A
BOV-1B
BOV-1C
C1DELq21.1
DEL1q21.1
MDS014
RBM8
RBM8B
TAR
Y14
ZNRP
ZRNP1
Species Homo sapiens
 Database cross references - RBM8A
ExoCarta ExoCarta_9939
Vesiclepedia VP_9939
Entrez Gene 9939
HGNC 9905
MIM 605313
UniProt Q9Y5S9  
 RBM8A identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Prostate cancer cells 25844599    
T lymphocytes 34108659    
 Gene ontology annotations for RBM8A
Molecular Function
    RNA binding GO:0003723 HDA
    RNA binding GO:0003723 NAS
    mRNA binding GO:0003729 IBA
    mRNA binding GO:0003729 NAS
    protein binding GO:0005515 IPI
Biological Process
    nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 IMP
    regulation of alternative mRNA splicing, via spliceosome GO:0000381 IMP
    mRNA splicing, via spliceosome GO:0000398 IC
    mRNA splicing, via spliceosome GO:0000398 IDA
    mRNA export from nucleus GO:0006406 NAS
    regulation of translation GO:0006417 IEA
    RNA splicing GO:0008380 IBA
    regulation of mRNA processing GO:0050684 IDA
    regulation of mRNA processing GO:0050684 ISS
    regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:2000622 IDA
    regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:2000622 ISS
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleus GO:0005634 NAS
    nucleoplasm GO:0005654 TAS
    cytoplasm GO:0005737 NAS
    cytosol GO:0005829 NAS
    cytosol GO:0005829 TAS
    nuclear speck GO:0016607 IDA
    dendrite GO:0030425 IEA
    exon-exon junction complex GO:0035145 IBA
    exon-exon junction complex GO:0035145 IDA
    exon-exon junction complex GO:0035145 IPI
    exon-exon junction complex GO:0035145 ISS
    neuronal cell body GO:0043025 IEA
    U2-type catalytic step 1 spliceosome GO:0071006 IDA
    catalytic step 2 spliceosome GO:0071013 IDA
    exon-exon junction subcomplex mago-y14 GO:1990501 IPI
 Experiment description of studies that identified RBM8A in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
15
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
19
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
20
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
28
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
33
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for RBM8A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EIF3A 8661
Affinity Capture-MS Homo sapiens
2 UTRN 7402
Affinity Capture-MS Homo sapiens
3 TRMT1L 81627
Affinity Capture-MS Homo sapiens
4 PTMS 5763
Affinity Capture-MS Homo sapiens
5 SKIV2L 6499
Affinity Capture-MS Homo sapiens
6 EIF3C 8663
Affinity Capture-MS Homo sapiens
7 PDAP1 11333
Co-fractionation Homo sapiens
8 SRPRB 58477
Affinity Capture-MS Homo sapiens
9 DDX21 9188
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 THOC7 80145
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 TMEM263 90488
Affinity Capture-MS Homo sapiens
12 PARK7 11315
Affinity Capture-MS Homo sapiens
13 SOX2  
Affinity Capture-MS Homo sapiens
14 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
15 SMG9 56006
Affinity Capture-Western Homo sapiens
16 DARS 1615
Affinity Capture-MS Homo sapiens
17 CIAPIN1 57019
Co-fractionation Homo sapiens
18 GNS 2799
Co-fractionation Homo sapiens
19 RPS9 6203
Affinity Capture-MS Homo sapiens
20 GSPT1 2935
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
21 EIF3E 3646
Affinity Capture-MS Homo sapiens
22 MECP2 4204
Affinity Capture-MS Homo sapiens
23 RPS11 6205
Affinity Capture-MS Homo sapiens
24 SLU7  
Co-fractionation Homo sapiens
25 MLEC 9761
Co-fractionation Homo sapiens
26 RPL19 6143
Affinity Capture-MS Homo sapiens
27 RBM14 10432
Co-fractionation Homo sapiens
28 KIF14 9928
Affinity Capture-MS Homo sapiens
29 RBMX 27316
Co-fractionation Homo sapiens
30 CHMP4C 92421
Affinity Capture-MS Homo sapiens
31 SRPK2 6733
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
32 SUPT5H 6829
Affinity Capture-MS Homo sapiens
33 C17orf85  
Affinity Capture-MS Homo sapiens
34 MAPRE1 22919
Affinity Capture-MS Homo sapiens
35 RPL18A 6142
Affinity Capture-MS Homo sapiens
36 PABPC1 26986
Affinity Capture-MS Homo sapiens
37 CTSC 1075
Affinity Capture-MS Homo sapiens
38 RPL31 6160
Affinity Capture-MS Homo sapiens
39 P4HB 5034
Affinity Capture-MS Homo sapiens
40 NOB1  
Affinity Capture-MS Homo sapiens
41 RRP1B 23076
Affinity Capture-MS Homo sapiens
42 DDX39B 7919
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
43 SEC61B 10952
Affinity Capture-MS Homo sapiens
44 SRPK1 6732
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
45 SSR4 6748
Affinity Capture-MS Homo sapiens
46 EIF3G 8666
Affinity Capture-MS Homo sapiens
47 RNF40 9810
Affinity Capture-MS Homo sapiens
48 RBM39 9584
Affinity Capture-MS Homo sapiens
49 R3HCC1L  
Affinity Capture-Western Homo sapiens
50 ZNF622 90441
Affinity Capture-MS Homo sapiens
51 BCAP31 10134
Affinity Capture-MS Homo sapiens
52 EBNA1BP2 10969
Affinity Capture-MS Homo sapiens
53 EIF4E 1977
Affinity Capture-MS Homo sapiens
54 EIF2S2 8894
Affinity Capture-MS Homo sapiens
55 ZC3H11A  
Affinity Capture-MS Homo sapiens
56 LUC7L2 51631
Co-fractionation Homo sapiens
57 MFAP1  
Affinity Capture-MS Homo sapiens
58 LSM3 27258
Co-fractionation Homo sapiens
59 C11orf98  
Affinity Capture-MS Homo sapiens
60 TMCO1 54499
Affinity Capture-MS Homo sapiens
61 ZMYND8 23613
Affinity Capture-MS Homo sapiens
62 DLST 1743
Affinity Capture-MS Homo sapiens
63 RPL35A 6165
Affinity Capture-MS Homo sapiens
64 NCLN 56926
Affinity Capture-MS Homo sapiens
65 STMN1 3925
Affinity Capture-MS Homo sapiens
66 UPF2 26019
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
67 GNL3 26354
Affinity Capture-MS Homo sapiens
68 RPS16 6217
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
69 YBX1 4904
Affinity Capture-MS Homo sapiens
70 POLR2J  
Affinity Capture-MS Homo sapiens
71 IARS 3376
Affinity Capture-MS Homo sapiens
72 CHTOP  
Affinity Capture-MS Homo sapiens
73 EIF3I 8668
Affinity Capture-MS Homo sapiens
74 TKT 7086
Affinity Capture-MS Homo sapiens
75 G3BP2 9908
Affinity Capture-MS Homo sapiens
76 PSMA1 5682
Co-fractionation Homo sapiens
77 PWP1 11137
Affinity Capture-MS Homo sapiens
78 LARP7 51574
Affinity Capture-MS Homo sapiens
79 RPS24 6229
Affinity Capture-MS Homo sapiens
80 NCL 4691
Affinity Capture-MS Homo sapiens
81 ALYREF 10189
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
82 EIF4B 1975
Affinity Capture-MS Homo sapiens
83 CLTA 1211
Co-fractionation Homo sapiens
84 RPL23A 6147
Affinity Capture-MS Homo sapiens
85 SEC61A1 29927
Affinity Capture-MS Homo sapiens
86 PDHA1 5160
Affinity Capture-MS Homo sapiens
87 LUZP4  
Affinity Capture-MS Homo sapiens
88 HBB 3043
Affinity Capture-RNA Homo sapiens
89 NCBP1 4686
Affinity Capture-MS Homo sapiens
90 ANP32A 8125
Affinity Capture-MS Homo sapiens
91 EIF2S3 1968
Affinity Capture-MS Homo sapiens
92 EIF3K 27335
Affinity Capture-MS Homo sapiens
93 RPS17 6218
Affinity Capture-MS Homo sapiens
94 FMR1 2332
Affinity Capture-MS Homo sapiens
95 NACA 4666
Affinity Capture-MS Homo sapiens
96 SF3B1 23451
Affinity Capture-MS Homo sapiens
97 SRPR 6734
Affinity Capture-MS Homo sapiens
98 CHCHD1  
Proximity Label-MS Homo sapiens
99 RPL14 9045
Affinity Capture-MS Homo sapiens
100 EIF4A1 1973
Affinity Capture-MS Homo sapiens
101 RSBN1  
Affinity Capture-MS Homo sapiens
102 SNRPF 6636
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
103 RPS3 6188
Affinity Capture-MS Homo sapiens
104 SDE2  
Affinity Capture-MS Homo sapiens
105 RNPS1 10921
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
106 NCBP2-AS2  
Affinity Capture-MS Homo sapiens
107 RBM3 5935
Affinity Capture-MS Homo sapiens
108 TCF12  
Two-hybrid Homo sapiens
109 H1FX 8971
Affinity Capture-MS Homo sapiens
110 PRC1 9055
Affinity Capture-MS Homo sapiens
111 MAGOHB 55110
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
112 NPM1 4869
Affinity Capture-MS Homo sapiens
113 SRRM2 23524
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
114 OBSL1 23363
Affinity Capture-MS Homo sapiens
115 DDX6 1656
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
116 RBM42  
Affinity Capture-MS Homo sapiens
117 LARP4B 23185
Affinity Capture-MS Homo sapiens
118 LSM2 57819
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
119 HNRNPA0 10949
Affinity Capture-MS Homo sapiens
120 PRPF8 10594
Affinity Capture-MS Homo sapiens
121 USP10 9100
Affinity Capture-MS Homo sapiens
122 RPL4 6124
Affinity Capture-MS Homo sapiens
123 RBM28 55131
Affinity Capture-MS Homo sapiens
124 DRG1 4733
Affinity Capture-MS Homo sapiens
125 ACIN1 22985
Affinity Capture-MS Homo sapiens
126 NCAPH2  
Co-fractionation Homo sapiens
127 SNRNP200 23020
Affinity Capture-MS Homo sapiens
128 RPL35 11224
Affinity Capture-MS Homo sapiens
129 NKRF 55922
Affinity Capture-MS Homo sapiens
130 RAD18  
Affinity Capture-MS Homo sapiens
131 NOMO3 408050
Affinity Capture-MS Homo sapiens
132 LYAR 55646
Affinity Capture-MS Homo sapiens
133 EHBP1L1 254102
Co-fractionation Homo sapiens
134 MAGOH 4116
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
135 APTX  
Affinity Capture-MS Homo sapiens
136 NFX1  
Affinity Capture-MS Homo sapiens
137 SNRPB2 6629
Affinity Capture-MS Homo sapiens
138 RPLP0 6175
Affinity Capture-MS Homo sapiens
139 HNRNPD 3184
Affinity Capture-MS Homo sapiens
140 RPL32 6161
Affinity Capture-MS Homo sapiens
141 DOC2B  
Affinity Capture-MS Homo sapiens
142 RPS2 6187
Affinity Capture-MS Homo sapiens
143 POP1 10940
Affinity Capture-MS Homo sapiens
144 EIF6 3692
Affinity Capture-MS Homo sapiens
145 NCBP2 22916
Affinity Capture-MS Homo sapiens
146 MTX2 10651
Proximity Label-MS Homo sapiens
147 RPS7 6201
Affinity Capture-MS Homo sapiens
148 YLPM1 56252
Affinity Capture-MS Homo sapiens
149 SLK 9748
Co-fractionation Homo sapiens
150 UPF3A  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
151 SPTBN1 6711
Co-fractionation Homo sapiens
152 RPS27 6232
Affinity Capture-MS Homo sapiens
153 MYC  
Affinity Capture-MS Homo sapiens
154 EGFR 1956
Negative Genetic Homo sapiens
155 FKBP3 2287
Affinity Capture-MS Homo sapiens
156 DDRGK1 65992
Affinity Capture-MS Homo sapiens
157 EDF1 8721
Affinity Capture-MS Homo sapiens
158 FYTTD1  
Affinity Capture-MS Homo sapiens
159 PGAM1 5223
Affinity Capture-MS Homo sapiens
160 NOP16 51491
Affinity Capture-MS Homo sapiens
161 FTSJ3 117246
Affinity Capture-MS Homo sapiens
162 LARP4 113251
Affinity Capture-MS Homo sapiens
163 DPH1  
Two-hybrid Homo sapiens
164 EIF3H 8667
Affinity Capture-MS Homo sapiens
165 CKMT2  
Affinity Capture-MS Homo sapiens
166 PA2G4 5036
Affinity Capture-MS Homo sapiens
167 RPL13 6137
Affinity Capture-MS Homo sapiens
168 C17orf80 55028
Proximity Label-MS Homo sapiens
169 PRKCSH 5589
Affinity Capture-MS Homo sapiens
170 PRRC2A 7916
Affinity Capture-MS Homo sapiens
171 TOE1 114034
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
172 PARP1 142
Affinity Capture-MS Homo sapiens
173 ILF3 3609
Affinity Capture-MS Homo sapiens
174 RPS12 6206
Affinity Capture-MS Homo sapiens
175 RPS4X 6191
Affinity Capture-MS Homo sapiens
176 RPS5 6193
Affinity Capture-MS Homo sapiens
177 RPS26 6231
Affinity Capture-MS Homo sapiens
178 EIF3J 8669
Affinity Capture-MS Homo sapiens
179 DHX38 9785
Co-fractionation Homo sapiens
180 RPL7A 6130
Affinity Capture-MS Homo sapiens
181 C2CD5 9847
Affinity Capture-MS Homo sapiens
182 RPS29 6235
Affinity Capture-MS Homo sapiens
183 RNF113A 7737
Affinity Capture-MS Homo sapiens
184 TEX10 54881
Affinity Capture-MS Homo sapiens
185 CAPN2 824
Co-fractionation Homo sapiens
186 ALKBH5 54890
Affinity Capture-MS Homo sapiens
187 MCM7 4176
Two-hybrid Homo sapiens
188 RPSA 3921
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
189 SLIRP 81892
Co-fractionation Homo sapiens
190 RPL26L1 51121
Affinity Capture-MS Homo sapiens
191 MARCKS 4082
Affinity Capture-MS Homo sapiens
192 SDAD1  
Affinity Capture-MS Homo sapiens
193 RPS19 6223
Affinity Capture-MS Homo sapiens
194 ORC2  
Affinity Capture-MS Homo sapiens
195 CCDC9  
Affinity Capture-MS Homo sapiens
196 PEBP1 5037
Affinity Capture-MS Homo sapiens
197 ATG13 9776
Affinity Capture-MS Homo sapiens
198 DIMT1 27292
Affinity Capture-MS Homo sapiens
199 RPL10A 4736
Affinity Capture-MS Homo sapiens
200 EIF3B 8662
Affinity Capture-MS Homo sapiens
201 HIST1H2AG 8969
Cross-Linking-MS (XL-MS) Homo sapiens
202 LSG1  
Affinity Capture-MS Homo sapiens
203 SF3A2 8175
Affinity Capture-MS Homo sapiens
204 UGDH 7358
Affinity Capture-MS Homo sapiens
205 PGD 5226
Affinity Capture-MS Homo sapiens
206 RPL29 6159
Affinity Capture-MS Homo sapiens
207 MTDH 92140
Affinity Capture-MS Homo sapiens
208 RPS3A 6189
Affinity Capture-MS Homo sapiens
209 THOC1 9984
Affinity Capture-MS Homo sapiens
210 PABPC4 8761
Affinity Capture-MS Homo sapiens
211 BRIX1 55299
Affinity Capture-MS Homo sapiens
212 RPL27 6155
Affinity Capture-MS Homo sapiens
213 RAD23B 5887
Co-fractionation Homo sapiens
214 NOP2 4839
Affinity Capture-MS Homo sapiens
215 P4HA1 5033
Affinity Capture-MS Homo sapiens
216 RPL9 6133
Affinity Capture-MS Homo sapiens
217 PARK2  
Affinity Capture-MS Homo sapiens
218 RPS10 6204
Affinity Capture-MS Homo sapiens
219 MARS 4141
Affinity Capture-MS Homo sapiens
220 PSMB1 5689
Co-fractionation Homo sapiens
221 PNO1 56902
Affinity Capture-MS Homo sapiens
222 RPL5 6125
Affinity Capture-MS Homo sapiens
223 DEK 7913
Co-fractionation Homo sapiens
224 RAE1 8480
Affinity Capture-MS Homo sapiens
225 LAS1L 81887
Affinity Capture-MS Homo sapiens
226 RPL36 25873
Affinity Capture-MS Homo sapiens
227 RPL37A 6168
Affinity Capture-MS Homo sapiens
228 RPN1 6184
Affinity Capture-MS Homo sapiens
229 DHX9 1660
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
230 SEC61G 23480
Affinity Capture-MS Homo sapiens
231 HNRNPA3 220988
Affinity Capture-MS Homo sapiens
232 MYBBP1A 10514
Affinity Capture-MS Homo sapiens
233 DNM1L 10059
Affinity Capture-MS Homo sapiens
234 RPL11 6135
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
235 LARP1 23367
Affinity Capture-MS Homo sapiens
236 SF3B2 10992
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
237 ZBTB2 57621
Affinity Capture-MS Homo sapiens
238 RPL15 6138
Affinity Capture-MS Homo sapiens
239 SMG8 55181
Affinity Capture-Western Homo sapiens
240 EEF2 1938
Affinity Capture-MS Homo sapiens
241 NR3C1 2908
Proximity Label-MS Homo sapiens
242 RPL21 6144
Affinity Capture-MS Homo sapiens
243 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
244 DHX30 22907
Affinity Capture-MS Homo sapiens
245 FAM195B 348262
Affinity Capture-MS Homo sapiens
246 RBM33  
Affinity Capture-MS Homo sapiens
247 BASP1 10409
Affinity Capture-MS Homo sapiens
248 PUS7 54517
Co-fractionation Homo sapiens
249 PDCD4 27250
Affinity Capture-MS Homo sapiens
250 CDC42BPA 8476
Affinity Capture-MS Homo sapiens
251 RPS13 6207
Affinity Capture-MS Homo sapiens
252 RPS14 6208
Affinity Capture-MS Homo sapiens
253 TOP1 7150
Affinity Capture-MS Homo sapiens
254 RPL12 6136
Affinity Capture-MS Homo sapiens
255 RPL22 6146
Affinity Capture-MS Homo sapiens
256 RPLP1 6176
Affinity Capture-MS Homo sapiens
257 RPL18 6141
Affinity Capture-MS Homo sapiens
258 RNF2  
Affinity Capture-MS Homo sapiens
259 KTN1 3895
Affinity Capture-MS Homo sapiens
260 TSR1 55720
Affinity Capture-MS Homo sapiens
261 TOP3B 8940
Affinity Capture-MS Homo sapiens
262 TPM3 7170
Affinity Capture-MS Homo sapiens
263 EIF2S1 1965
Affinity Capture-MS Homo sapiens
264 POP7  
Affinity Capture-MS Homo sapiens
265 CPSF6 11052
Affinity Capture-MS Homo sapiens
266 RPS25 6230
Affinity Capture-MS Homo sapiens
267 RPL6 6128
Affinity Capture-MS Homo sapiens
268 RPS21 6227
Affinity Capture-MS Homo sapiens
269 KAT2B  
Protein-RNA Homo sapiens
270 PRRC2C 23215
Affinity Capture-MS Homo sapiens
271 IKBKG 8517
Reconstituted Complex Homo sapiens
272 SNRPA 6626
Affinity Capture-MS Homo sapiens
273 HNRNPM 4670
Co-fractionation Homo sapiens
274 THRAP3 9967
Affinity Capture-MS Homo sapiens
275 SEPHS2  
Co-fractionation Homo sapiens
276 RPL34 6164
Affinity Capture-MS Homo sapiens
277 PCNA 5111
Co-fractionation Homo sapiens
278 PDZD8 118987
Affinity Capture-MS Homo sapiens
279 UFL1 23376
Affinity Capture-MS Homo sapiens
280 RPL38 6169
Affinity Capture-MS Homo sapiens
281 TFCP2L1  
Co-fractionation Homo sapiens
282 GTPBP4 23560
Affinity Capture-MS Homo sapiens
283 SERPINB12 89777
Affinity Capture-MS Homo sapiens
284 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
285 RPL8 6132
Affinity Capture-MS Homo sapiens
286 SMG1 23049
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
287 RPL28 6158
Affinity Capture-MS Homo sapiens
288 RPS27L 51065
Affinity Capture-MS Homo sapiens
289 SERBP1 26135
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
290 RPL36AL 6166
Affinity Capture-MS Homo sapiens
291 SSRP1 6749
Affinity Capture-MS Homo sapiens
292 DAP  
Affinity Capture-MS Homo sapiens
293 CASC3  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
294 Magoh  
Affinity Capture-MS Mus musculus
295 EIF3L 51386
Affinity Capture-MS Homo sapiens
296 UNC119B 84747
Co-fractionation Homo sapiens
297 GNL2 29889
Affinity Capture-MS Homo sapiens
298 UBE2H 7328
Affinity Capture-MS Homo sapiens
299 SRP19 6728
Affinity Capture-MS Homo sapiens
300 IGF2BP1 10642
Affinity Capture-MS Homo sapiens
301 RPS18 6222
Affinity Capture-MS Homo sapiens
302 QARS 5859
Affinity Capture-MS Homo sapiens
303 SMG6  
Affinity Capture-Western Homo sapiens
304 VAPA 9218
Affinity Capture-MS Homo sapiens
305 RPL30 6156
Affinity Capture-MS Homo sapiens
306 NOP9 161424
Affinity Capture-MS Homo sapiens
307 RPL13A 23521
Affinity Capture-MS Homo sapiens
308 FBXO25  
Biochemical Activity Homo sapiens
309 ZC3H14  
Affinity Capture-MS Homo sapiens
310 RPL10 6134
Affinity Capture-MS Homo sapiens
311 TDRD3  
Affinity Capture-Western Homo sapiens
312 CALM1 801
Affinity Capture-MS Homo sapiens
313 DHX57 90957
Affinity Capture-MS Homo sapiens
314 CCDC124 115098
Affinity Capture-MS Homo sapiens
315 APP 351
Reconstituted Complex Homo sapiens
316 AVEN 57099
Affinity Capture-MS Homo sapiens
317 ILF2 3608
Affinity Capture-MS Homo sapiens
318 GSK3A 2931
Affinity Capture-MS Homo sapiens
319 SRP54 6729
Affinity Capture-MS Homo sapiens
320 RPS20 6224
Affinity Capture-MS Homo sapiens
321 RPL24 6152
Affinity Capture-MS Homo sapiens
322 SNRPC 6631
Affinity Capture-MS Homo sapiens
323 HMGA1 3159
Affinity Capture-MS Homo sapiens
324 ABCE1 6059
Affinity Capture-MS Homo sapiens
325 STAU2 27067
Affinity Capture-MS Homo sapiens
326 SRP68 6730
Affinity Capture-MS Homo sapiens
327 P3H1 64175
Affinity Capture-MS Homo sapiens
328 MYCN  
Affinity Capture-MS Homo sapiens
329 SSR3 6747
Affinity Capture-MS Homo sapiens
330 NEDD4 4734
Affinity Capture-MS Homo sapiens
331 RPS23 6228
Affinity Capture-MS Homo sapiens
332 LMNB1 4001
Affinity Capture-MS Homo sapiens
333 PPIB 5479
Affinity Capture-MS Homo sapiens
334 USP21  
Affinity Capture-MS Homo sapiens
335 ECT2 1894
Affinity Capture-MS Homo sapiens
336 STAU1 6780
Affinity Capture-MS Homo sapiens
337 DDX5 1655
Affinity Capture-MS Homo sapiens
338 SUMO2 6613
Affinity Capture-MS Homo sapiens
339 RPL27A 6157
Affinity Capture-MS Homo sapiens
340 PABPN1 8106
Affinity Capture-MS Homo sapiens
341 CDK9 1025
Affinity Capture-MS Homo sapiens
342 ZC3H15 55854
Affinity Capture-MS Homo sapiens
343 RPS15A 6210
Affinity Capture-MS Homo sapiens
344 ASCC3 10973
Affinity Capture-MS Homo sapiens
345 PRPF4B 8899
Affinity Capture-MS Homo sapiens
346 RPLP2 6181
Affinity Capture-MS Homo sapiens
347 FANCD2  
Affinity Capture-MS Homo sapiens
348 UPF1 5976
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
349 EIF4G1 1981
Affinity Capture-MS Homo sapiens
350 PNN 5411
Affinity Capture-MS Homo sapiens
351 SNRPB 6628
Affinity Capture-MS Homo sapiens
352 RPS6 6194
Affinity Capture-MS Homo sapiens
353 RPL3 6122
Affinity Capture-MS Homo sapiens
354 RPL7 6129
Affinity Capture-MS Homo sapiens
355 SUZ12  
Affinity Capture-MS Homo sapiens
356 SART1 9092
Affinity Capture-MS Homo sapiens
357 NXF1 10482
Reconstituted Complex Homo sapiens
358 SF3A1 10291
Affinity Capture-MS Homo sapiens
359 IPO13 9670
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
360 UPF3B 65109
Reconstituted Complex Homo sapiens
361 KRAS 3845
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
362 EIF4A2 1974
Affinity Capture-MS Homo sapiens
363 WIBG 84305
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
364 EIF3M 10480
Affinity Capture-MS Homo sapiens
365 MGEA5 10724
Co-fractionation Homo sapiens
366 KIAA1522 57648
Affinity Capture-MS Homo sapiens
367 EIF3D 8664
Affinity Capture-MS Homo sapiens
368 PKP3 11187
Affinity Capture-MS Homo sapiens
369 EXOSC10 5394
Affinity Capture-MS Homo sapiens
370 GLUD1 2746
Affinity Capture-MS Homo sapiens
371 RRBP1 6238
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
372 SRRM1 10250
Affinity Capture-MS Homo sapiens
373 ERH 2079
Affinity Capture-MS Homo sapiens
374 PDIA4 9601
Affinity Capture-MS Homo sapiens
375 NUFIP2 57532
Affinity Capture-MS Homo sapiens
376 SAP18 10284
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
377 HNRNPA2B1 3181
Affinity Capture-MS Homo sapiens
378 ATXN2 6311
Affinity Capture-MS Homo sapiens
379 RPS15 6209
Affinity Capture-MS Homo sapiens
380 SRP72 6731
Affinity Capture-MS Homo sapiens
381 EIF4A3 9775
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
382 RPS28 6234
Affinity Capture-MS Homo sapiens
383 TRIP4 9325
Affinity Capture-MS Homo sapiens
384 RPL23 9349
Affinity Capture-MS Homo sapiens
385 RPS8 6202
Affinity Capture-MS Homo sapiens
386 SOD1 6647
Affinity Capture-MS Homo sapiens
387 ZFP36L1  
Affinity Capture-Western Homo sapiens
388 HNRNPU 3192
Affinity Capture-MS Homo sapiens
389 GNB2L1 10399
Affinity Capture-MS Homo sapiens
390 LTV1  
Affinity Capture-MS Homo sapiens
391 RPL17 6139
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here