Gene description for BCL2L1
Gene name BCL2-like 1
Gene symbol BCL2L1
Other names/aliases BCL-XL/S
BCL2L
BCLX
BCLXL
BCLXS
Bcl-X
PPP1R52
bcl-xL
bcl-xS
Species Homo sapiens
 Database cross references - BCL2L1
ExoCarta ExoCarta_598
Vesiclepedia VP_598
Entrez Gene 598
HGNC 992
MIM 600039
UniProt Q07817  
 BCL2L1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for BCL2L1
Molecular Function
    protein binding GO:0005515 IPI
    channel activity GO:0015267 IBA
    protein kinase binding GO:0019901 IPI
    identical protein binding GO:0042802 IPI
    BH3 domain binding GO:0051434 IPI
Biological Process
    ovarian follicle development GO:0001541 IEA
    in utero embryonic development GO:0001701 IEA
    release of cytochrome c from mitochondria GO:0001836 IBA
    release of cytochrome c from mitochondria GO:0001836 IDA
    endocytosis GO:0006897 IEA
    germ cell development GO:0007281 IEA
    spermatogenesis GO:0007283 IEA
    male gonad development GO:0008584 IEA
    intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 IBA
    apoptotic mitochondrial changes GO:0008637 TAS
    fertilization GO:0009566 IEA
    negative regulation of autophagy GO:0010507 TAS
    regulation of cytokinesis GO:0032465 IMP
    positive regulation of mononuclear cell proliferation GO:0032946 IEA
    response to cytokine GO:0034097 IDA
    ectopic germ cell programmed cell death GO:0035234 IEA
    regulation of growth GO:0040008 IEA
    positive regulation of apoptotic process GO:0043065 IBA
    negative regulation of apoptotic process GO:0043066 IDA
    negative regulation of apoptotic process GO:0043066 IDA
    negative regulation of apoptotic process GO:0043066 IMP
    negative regulation of neuron apoptotic process GO:0043524 IEA
    dendritic cell proliferation GO:0044565 IEA
    response to cycloheximide GO:0046898 IEA
    regulation of mitochondrial membrane permeability GO:0046902 IDA
    epithelial cell proliferation GO:0050673 IEA
    negative regulation of developmental process GO:0051093 IEA
    neuron apoptotic process GO:0051402 IEA
    defense response to virus GO:0051607 IDA
    regulation of mitochondrial membrane potential GO:0051881 IDA
    transmembrane transport GO:0055085 IEA
    cellular response to amino acid stimulus GO:0071230 IEA
    cellular response to alkaloid GO:0071312 IEA
    cellular response to gamma radiation GO:0071480 IEA
    apoptotic process in bone marrow cell GO:0071839 IEA
    negative regulation of release of cytochrome c from mitochondria GO:0090201 IC
    negative regulation of release of cytochrome c from mitochondria GO:0090201 IDA
    dendritic cell apoptotic process GO:0097048 IEA
    extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 IBA
    hepatocyte apoptotic process GO:0097284 IEA
    negative regulation of execution phase of apoptosis GO:1900118 IDA
    negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway GO:1901029 IDA
    negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 IDA
    negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage GO:1902230 IDA
    negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway GO:1902236 IDA
    negative regulation of protein localization to plasma membrane GO:1903077 IDA
    negative regulation of reproductive process GO:2000242 IEA
    negative regulation of dendritic cell apoptotic process GO:2000669 IEA
    negative regulation of anoikis GO:2000811 IMP
    negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 TAS
    negative regulation of intrinsic apoptotic signaling pathway GO:2001243 IDA
Subcellular Localization
    cytoplasm GO:0005737 IDA
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IDA
    mitochondrial outer membrane GO:0005741 IBA
    mitochondrial outer membrane GO:0005741 IDA
    mitochondrial outer membrane GO:0005741 NAS
    mitochondrial outer membrane GO:0005741 TAS
    mitochondrial inner membrane GO:0005743 IEA
    mitochondrial matrix GO:0005759 IEA
    endoplasmic reticulum GO:0005783 IEA
    centrosome GO:0005813 IDA
    cytosol GO:0005829 TAS
    synaptic vesicle membrane GO:0030672 IEA
    nuclear membrane GO:0031965 IEA
    Bcl-2 family protein complex GO:0097136 IDA
    Bcl-2 family protein complex GO:0097136 IPI
 Experiment description of studies that identified BCL2L1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for BCL2L1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GSTP1 2950
Affinity Capture-MS Homo sapiens
2 HRK  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Protein-peptide Homo sapiens
3 LARP1 23367
Two-hybrid Homo sapiens
4 HDAC4  
Affinity Capture-MS Homo sapiens
5 RAB1A 5861
Affinity Capture-MS Homo sapiens
6 ATG5 9474
Affinity Capture-Western Homo sapiens
7 WWP1 11059
Affinity Capture-MS Homo sapiens
8 ACTR2 10097
Affinity Capture-MS Homo sapiens
9 PSMD11 5717
Affinity Capture-MS Homo sapiens
10 MOAP1  
Affinity Capture-Western Homo sapiens
11 SIVA1  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
12 BCL2L11  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
FRET Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 SPNS1 83985
Affinity Capture-Western Homo sapiens
14 USP14 9097
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
15 CALM1 801
Affinity Capture-MS Homo sapiens
16 PARK7 11315
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
17 RTN4 57142
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
18 PRKDC 5591
Affinity Capture-MS Homo sapiens
19 PSEN2 5664
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
20 ZAR1L  
Affinity Capture-MS Homo sapiens
21 PDE2A  
Affinity Capture-MS Homo sapiens
22 PPP1CC 5501
Affinity Capture-Western Homo sapiens
23 CAPZB 832
Affinity Capture-MS Homo sapiens
24 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
25 CASP1  
Affinity Capture-Western Homo sapiens
26 RAD9A  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
27 APAF1 317
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
28 ABLIM1 3983
Affinity Capture-MS Homo sapiens
29 MYO5B 4645
Affinity Capture-MS Homo sapiens
30 WSB2 55884
Affinity Capture-MS Homo sapiens
31 HGS 9146
Affinity Capture-MS Homo sapiens
32 ZFYVE1 53349
Two-hybrid Homo sapiens
33 BCL2L14  
Affinity Capture-Western Homo sapiens
34 RTN1 6252
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
35 DYNLL1 8655
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
36 VDAC1 7416
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
37 ZNF219  
Two-hybrid Homo sapiens
38 BECN1 8678
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
39 KLHL20  
Affinity Capture-MS Homo sapiens
40 METTL23  
Two-hybrid Homo sapiens
41 CFLAR  
Affinity Capture-Western Homo sapiens
42 RIC3  
Two-hybrid Homo sapiens
43 HSPD1 3329
Affinity Capture-MS Homo sapiens
44 BFAR  
Affinity Capture-Western Homo sapiens
45 TPT1 7178
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
46 MTNR1B  
Two-hybrid Homo sapiens
47 PPP1CA 5499
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
48 MTCH2 23788
Affinity Capture-MS Homo sapiens
49 BLID  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
50 BNIP1 662
Reconstituted Complex Homo sapiens
51 Bcl2l11  
Protein-peptide Mus musculus
Two-hybrid Mus musculus
Affinity Capture-Western Mus musculus
52 REEP4  
Two-hybrid Homo sapiens
53 PARK2  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
Affinity Capture-Western Homo sapiens
54 PGAM5 192111
Affinity Capture-Western Homo sapiens
55 CLU 1191
Affinity Capture-Western Homo sapiens
Co-crystal Structure Homo sapiens
56 FUNDC2 65991
Affinity Capture-MS Homo sapiens
57 GNAI1 2770
Affinity Capture-MS Homo sapiens
58 GORAB 92344
Two-hybrid Homo sapiens
59 UBE2I 7329
Two-hybrid Homo sapiens
60 GIMAP5  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
61 PMAIP1  
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Protein-peptide Homo sapiens
62 PDS5A 23244
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 TMEM50B 757
Two-hybrid Homo sapiens
64 YWHAH 7533
Affinity Capture-MS Homo sapiens
65 HIST1H1E 3008
Affinity Capture-MS Homo sapiens
66 CTNNB1 1499
Affinity Capture-MS Homo sapiens
67 TMEM259 91304
Affinity Capture-MS Homo sapiens
68 CREB3  
Two-hybrid Homo sapiens
69 YWHAQ 10971
Affinity Capture-MS Homo sapiens
70 ACTB 60
Two-hybrid Homo sapiens
71 BCL2L1 598
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
72 MYH10 4628
Affinity Capture-MS Homo sapiens
73 DYNLL2 140735
Affinity Capture-MS Homo sapiens
74 BNIPL  
Two-hybrid Homo sapiens
75 MAPK8 5599
Co-localization Homo sapiens
76 RPS15A 6210
Affinity Capture-MS Homo sapiens
77 VDAC2 7417
Affinity Capture-MS Homo sapiens
78 C10orf67  
Two-hybrid Homo sapiens
79 JUP 3728
Affinity Capture-MS Homo sapiens
80 G0S2  
Two-hybrid Homo sapiens
81 BBC3  
Affinity Capture-Western Homo sapiens
Co-crystal Structure Homo sapiens
Protein-peptide Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
82 PTN  
Two-hybrid Homo sapiens
83 RBM5  
Two-hybrid Homo sapiens
84 AVEN 57099
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
85 ANO6 196527
Affinity Capture-MS Homo sapiens
86 TUBB 203068
Affinity Capture-MS Homo sapiens
87 GLOD4 51031
Two-hybrid Homo sapiens
88 PSEN1 5663
Two-hybrid Homo sapiens
89 BAX 581
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Dosage Rescue Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
Affinity Capture-MS Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
90 ZHX1  
Two-hybrid Homo sapiens
91 PINK1  
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
Affinity Capture-Western Homo sapiens
92 DOCK7 85440
Two-hybrid Homo sapiens
93 IKZF3  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
94 MTIF3  
Two-hybrid Homo sapiens
95 CRYAB 1410
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
96 CRYAA 1409
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
97 ERGIC3 51614
Two-hybrid Homo sapiens
98 BCAP31 10134
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
99 CASP2  
Phenotypic Suppression Homo sapiens
100 UHRF2  
Far Western Homo sapiens
101 FKBP8 23770
Affinity Capture-Western Homo sapiens
102 HNRNPA1 3178
Protein-RNA Homo sapiens
103 MYO1C 4641
Affinity Capture-MS Homo sapiens
104 AP2M1 1173
Affinity Capture-MS Homo sapiens
105 BLK 640
Reconstituted Complex Homo sapiens
106 PPHLN1  
Two-hybrid Homo sapiens
107 TUBA4A 7277
Affinity Capture-MS Homo sapiens
108 TP53BP2  
Two-hybrid Homo sapiens
Protein-peptide Homo sapiens
Co-crystal Structure Homo sapiens
109 Hsph1 15505
Affinity Capture-MS Mus musculus
110 TRIM32 22954
Affinity Capture-Western Homo sapiens
111 UBR1 197131
Two-hybrid Homo sapiens
112 GNAS 2778
Affinity Capture-MS Homo sapiens
113 CASP9 842
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
114 FABP5 2171
Affinity Capture-MS Homo sapiens
115 MTOR 2475
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
116 TMOD3 29766
Affinity Capture-MS Homo sapiens
117 RPL12 6136
Affinity Capture-MS Homo sapiens
118 GNLY  
Two-hybrid Homo sapiens
119 RAF1 5894
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
120 FAIM2  
Affinity Capture-Western Homo sapiens
121 TMEM101  
Affinity Capture-MS Homo sapiens
122 BNIP3 664
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
123 LPPR2  
Affinity Capture-MS Homo sapiens
124 AKT1 207
Biochemical Activity Homo sapiens
125 FLOT1 10211
Affinity Capture-MS Homo sapiens
126 PHGDH 26227
Affinity Capture-MS Homo sapiens
127 Bax 12028
Two-hybrid Mus musculus
128 EEF1A1 1915
Affinity Capture-MS Homo sapiens
129 C6orf222  
Two-hybrid Homo sapiens
130 MIEF1  
Affinity Capture-Western Homo sapiens
131 SVIL 6840
Affinity Capture-MS Homo sapiens
132 GALNT10 55568
Affinity Capture-MS Homo sapiens
133 SPTBN1 6711
Affinity Capture-MS Homo sapiens
134 BMF  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Two-hybrid Homo sapiens
Protein-peptide Homo sapiens
135 SPTAN1 6709
Affinity Capture-MS Homo sapiens
136 RPS3 6188
Affinity Capture-MS Homo sapiens
137 BAD  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Two-hybrid Homo sapiens
FRET Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
138 TP53 7157
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
139 PDIA4 9601
Two-hybrid Homo sapiens
140 MCL1 4170
Affinity Capture-Western Homo sapiens
141 TLE1 7088
Two-hybrid Homo sapiens
142 CASP8 841
Phenotypic Suppression Homo sapiens
143 BID  
Co-localization Homo sapiens
Protein-peptide Homo sapiens
Protein-peptide Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
144 ABL1 25
Affinity Capture-Western Homo sapiens
145 HSPB1 3315
Affinity Capture-MS Homo sapiens
146 CCT7 10574
Affinity Capture-MS Homo sapiens
147 RPS26 6231
Affinity Capture-MS Homo sapiens
148 BIK  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Protein-peptide Homo sapiens
149 BAK1 578
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Protein-peptide Homo sapiens
FRET Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
150 UBB 7314
Affinity Capture-MS Homo sapiens
151 PLD3 23646
Two-hybrid Homo sapiens
152 GAPDH 2597
Affinity Capture-MS Homo sapiens
153 BCL2  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
154 PCBP1 5093
Affinity Capture-MS Homo sapiens
155 CAD 790
Affinity Capture-MS Homo sapiens
156 FBP1 2203
Two-hybrid Homo sapiens
157 RPL8 6132
Affinity Capture-MS Homo sapiens
158 KRAS 3845
Synthetic Lethality Homo sapiens
Affinity Capture-MS Homo sapiens
159 HNRNPU 3192
Affinity Capture-MS Homo sapiens
160 CYCS 54205
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
161 GOLM1 51280
Two-hybrid Homo sapiens
162 CASP8AP2  
Affinity Capture-Western Homo sapiens
163 IRS1 3667
Affinity Capture-Western Homo sapiens
164 ELOVL4  
Two-hybrid Homo sapiens
165 RANBP2 5903
Affinity Capture-MS Homo sapiens
166 CDKN2A 1029
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
167 EDRF1  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which BCL2L1 is involved
PathwayEvidenceSource
Apoptosis TAS Reactome
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members TAS Reactome
Cellular response to chemical stress TAS Reactome
Cellular responses to stimuli TAS Reactome
Cellular responses to stress TAS Reactome
Cytokine Signaling in Immune system TAS Reactome
Disease TAS Reactome
Diseases of signal transduction by growth factor receptors and second messengers TAS Reactome
FLT3 signaling in disease TAS Reactome
Immune System TAS Reactome
Infectious disease TAS Reactome
Inflammasomes TAS Reactome
Innate Immune System TAS Reactome
Interleukin-4 and Interleukin-13 signaling TAS Reactome
Intrinsic Pathway for Apoptosis TAS Reactome
KEAP1-NFE2L2 pathway TAS Reactome
MAPK family signaling cascades TAS Reactome
MAPK1/MAPK3 signaling TAS Reactome
NFE2L2 regulating tumorigenic genes TAS Reactome
Nuclear events mediated by NFE2L2 TAS Reactome
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways TAS Reactome
Programmed Cell Death TAS Reactome
RAF/MAP kinase cascade TAS Reactome
RAS processing TAS Reactome
SARS-CoV Infections TAS Reactome
SARS-CoV-1 Infection TAS Reactome
SARS-CoV-1-host interactions TAS Reactome
SARS-CoV-1-mediated effects on programmed cell death TAS Reactome
Signal Transduction TAS Reactome
Signaling by FLT3 ITD and TKD mutants TAS Reactome
Signaling by Interleukins TAS Reactome
STAT5 activation downstream of FLT3 ITD mutants TAS Reactome
The NLRP1 inflammasome TAS Reactome
Viral Infection Pathways TAS Reactome





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