Gene description for PSMD8
Gene name	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
Gene symbol	PSMD8
Other names/aliases	HEL-S-91n HIP6 HYPF Nin1p Rpn12 S14 p31
Species	Homo sapiens
Database cross references - PSMD8
ExoCarta	ExoCarta_5714
Entrez Gene	5714
HGNC	9566
UniProt	P48556
PSMD8 identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for PSMD8

Biological Process     negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle GO:0051436 TAS     anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 TAS     positive regulation of canonical Wnt signaling pathway GO:0090263 TAS     negative regulation of canonical Wnt signaling pathway GO:0090090 TAS     regulation of apoptotic process GO:0042981 TAS     antigen processing and presentation of exogenous peptide antigen via MHC class I GO:0042590 TAS     regulation of protein stability GO:0031647 IMP     antigen processing and presentation of peptide antigen via MHC class I GO:0002474 TAS     negative regulation of apoptotic process GO:0043066 TAS     protein polyubiquitination GO:0000209 TAS     positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition GO:0051437 TAS     mitotic cell cycle GO:0000278 TAS     G1/S transition of mitotic cell cycle GO:0000082 TAS     regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle GO:0051439 TAS     small molecule metabolic process GO:0044281 TAS     apoptotic process GO:0006915 TAS     innate immune response GO:0045087 TAS     positive regulation of protein targeting to mitochondrion GO:1903955 IMP     stimulatory C-type lectin receptor signaling pathway GO:0002223 TAS     cellular nitrogen compound metabolic process GO:0034641 TAS     DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 TAS     regulation of cellular amino acid metabolic process GO:0006521 TAS     viral process GO:0016032 TAS     gene expression GO:0010467 TAS     antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent GO:0002479 TAS     programmed cell death GO:0012501 TAS Subcellular Localization     proteasome accessory complex GO:0022624 ISS     nucleoplasm GO:0005654 TAS     proteasome regulatory particle GO:0005838 IEA     nucleus GO:0005634 IDA     cytosol GO:0005829 TAS     proteasome complex GO:0000502 IDA     extracellular exosome GO:0070062 IDA