Gene description for PRKCB
Gene name	protein kinase C, beta
Gene symbol	PRKCB
Other names/aliases	PKC-beta PKCB PRKCB1 PRKCB2
Species	Homo sapiens
Database cross references - PRKCB
ExoCarta	ExoCarta_5579
Entrez Gene	5579
HGNC	9395
MIM	176970
UniProt	P05771
PRKCB identified in exosomes derived from the following tissue/cell type
B cells	20458337
B cells	20458337
B cells	20458337
Hepatocellular carcinoma cells	26054723
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927
Platelets	25332113
Platelets	25332113
Platelets	25332113

Gene ontology annotations for PRKCB

Molecular Function     ATP binding GO:0005524 IEA     zinc ion binding GO:0008270 IEA     protein serine/threonine kinase activity GO:0004674 TAS     protein binding GO:0005515 IPI     protein kinase C binding GO:0005080 IPI     chromatin binding GO:0003682 IDA     protein kinase C activity GO:0004697 IEA     histone kinase activity (H3-T6 specific) GO:0035403 IDA     androgen receptor binding GO:0050681 IDA     calcium channel regulator activity GO:0005246 IEA     histone binding GO:0042393 IDA     ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 IMP Biological Process     cellular calcium ion homeostasis GO:0006874 IEA     vascular endothelial growth factor receptor signaling pathway GO:0048010 TAS     B cell receptor signaling pathway GO:0050853 ISS     positive regulation of B cell receptor signaling pathway GO:0050861 ISS     synaptic transmission GO:0007268 TAS     histone H3-T6 phosphorylation GO:0035408 IDA     regulation of transcription from RNA polymerase II promoter GO:0006357 IMP     platelet activation GO:0030168 TAS     blood coagulation GO:0007596 TAS     signal transduction GO:0007165 NAS     cellular response to carbohydrate stimulus GO:0071322 IEA     mitotic cell cycle GO:0000278 TAS     transcription, DNA-templated GO:0006351 IEA     B cell activation GO:0042113 ISS     mitotic nuclear envelope disassembly GO:0007077 TAS     calcium ion transport GO:0006816 IEA     intracellular signal transduction GO:0035556 IEA     protein phosphorylation GO:0006468 TAS     lipoprotein transport GO:0042953 TAS     negative regulation of insulin receptor signaling pathway GO:0046627 ISS     positive regulation of angiogenesis GO:0045766 ISS     negative regulation of glucose transport GO:0010829 ISS     positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 ISS     positive regulation of NF-kappaB transcription factor activity GO:0051092 ISS     positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 ISS     apoptotic process GO:0006915 IEA Subcellular Localization     extracellular exosome GO:0070062 IDA     cytoplasm GO:0005737 IDA     cytosol GO:0005829 TAS     plasma membrane GO:0005886 TAS     nucleoplasm GO:0005654 TAS     nucleus GO:0005634 IDA