Gene description for HIST1H1C
Gene name histone cluster 1, H1c
Gene symbol HIST1H1C
Other names/aliases H1.2
H1C
H1F2
H1s-1
Species Homo sapiens
 Database cross references - HIST1H1C
ExoCarta ExoCarta_3006
Vesiclepedia VP_3006
Entrez Gene 3006
HGNC 4716
MIM 142710
UniProt P16403  
 HIST1H1C identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 34887515    
Endothelial cells 26027894    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Mesenchymal stem cells 36408942    
Neuroblastoma cells 25944692    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Prostate cancer cells 25844599    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Squamous carcinoma cells 20124223    
Thymus 23844026    
 Gene ontology annotations for HIST1H1C
Molecular Function
    double-stranded DNA binding GO:0003690 IBA
    RNA binding GO:0003723 HDA
    protein binding GO:0005515 IPI
    structural constituent of chromatin GO:0030527 IEA
    chromatin DNA binding GO:0031490 IDA
    nucleosomal DNA binding GO:0031492 IBA
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IEA
    nucleosome assembly GO:0006334 IEA
    chromosome condensation GO:0030261 IBA
    negative regulation of DNA recombination GO:0045910 IBA
Subcellular Localization
    nucleosome GO:0000786 IEA
    euchromatin GO:0000791 IBA
    euchromatin GO:0000791 IDA
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified HIST1H1C in sEVs
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 494
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 496
MISEV standards
Biophysical techniques
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 497
MISEV standards
Biophysical techniques
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 498
MISEV standards
EM
Biophysical techniques
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 207
MISEV standards
EM
Biophysical techniques
TSG101|HSP70|FLOT1
Enriched markers
VDAC
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 208
MISEV standards
EM
Biophysical techniques
TSG101|HSP70|FLOT1
Enriched markers
VDAC
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 209
MISEV standards
Biophysical techniques
TSG101|HSP70|FLOT1
Enriched markers
VDAC
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 282
MISEV standards
CEM
Biophysical techniques
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
Negative markers
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
13
Experiment ID 283
MISEV standards
CEM
Biophysical techniques
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
Negative markers
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
14
Experiment ID 286
MISEV standards
CEM
Biophysical techniques
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
Negative markers
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
15
Experiment ID 1203
MISEV standards
EM
Biophysical techniques
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
16
Experiment ID 226
MISEV standards
EM
Biophysical techniques
GAPDH|CD9|FLOT1
Enriched markers
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
17
Experiment ID 234
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
18
Experiment ID 236
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
19
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
20
Experiment ID 224
MISEV standards
EM|AFM
Biophysical techniques
Alix|TSG101|CD63|CD81
Enriched markers
GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
21
Experiment ID 211
MISEV standards
EM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
cytochrome c|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
22
Experiment ID 212
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
Cytochrome C|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 275
MISEV standards
EM
Biophysical techniques
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
AIF
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
24
Experiment ID 834
MISEV standards
EM
Biophysical techniques
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
25
Experiment ID 835
MISEV standards
EM
Biophysical techniques
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
26
Experiment ID 191
MISEV standards
Biophysical techniques
Alix|CD81|CD9
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
27
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for HIST1H1C
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HIST2H2BE 8349
Affinity Capture-MS Homo sapiens
2 HDAC4  
Affinity Capture-MS Homo sapiens
3 AATF  
Affinity Capture-MS Homo sapiens
4 SKIV2L 6499
Affinity Capture-MS Homo sapiens
5 PDAP1 11333
Cross-Linking-MS (XL-MS) Homo sapiens
6 HIST1H2BH 8345
Cross-Linking-MS (XL-MS) Homo sapiens
7 KIF20A 10112
Affinity Capture-MS Homo sapiens
8 BRD2  
Affinity Capture-MS Homo sapiens
9 VHL  
Reconstituted Complex Homo sapiens
10 PRPF40A 55660
Cross-Linking-MS (XL-MS) Homo sapiens
11 PRKDC 5591
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
12 CENPA  
Co-purification Homo sapiens
13 APEX1 328
Cross-Linking-MS (XL-MS) Homo sapiens
14 ZNF70  
Affinity Capture-MS Homo sapiens
15 CENPU  
Affinity Capture-MS Homo sapiens
16 WDR76  
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
17 CDK5 1020
Cross-Linking-MS (XL-MS) Homo sapiens
18 HIST3H2A 92815
Cross-Linking-MS (XL-MS) Homo sapiens
19 BHLHA15  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 ASB9  
Affinity Capture-MS Homo sapiens
21 HELLS 3070
Affinity Capture-MS Homo sapiens
22 VPS4A 27183
Cross-Linking-MS (XL-MS) Homo sapiens
23 SFN 2810
Affinity Capture-MS Homo sapiens
24 BUD31 8896
Cross-Linking-MS (XL-MS) Homo sapiens
25 SREK1 140890
Affinity Capture-MS Homo sapiens
26 DYNLT1 6993
Proximity Label-MS Homo sapiens
27 KIF14 9928
Affinity Capture-MS Homo sapiens
28 SRSF6 6431
Affinity Capture-MS Homo sapiens
29 CHMP4C 92421
Affinity Capture-MS Homo sapiens
30 TCOF1 6949
Cross-Linking-MS (XL-MS) Homo sapiens
31 TRIM7  
Affinity Capture-MS Homo sapiens
32 LIN28B  
Affinity Capture-MS Homo sapiens
33 HIST1H2AG 8969
Cross-Linking-MS (XL-MS) Homo sapiens
34 YBX2 51087
Affinity Capture-MS Homo sapiens
35 HIST1H3E 8353
Affinity Capture-MS Homo sapiens
36 UBASH3B 84959
Affinity Capture-MS Homo sapiens
37 TRIM21 6737
Affinity Capture-MS Homo sapiens
38 RPL31 6160
Proximity Label-MS Homo sapiens
39 CBX6  
Affinity Capture-MS Homo sapiens
40 HIST1H1C 3006
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
41 Mapk13  
Affinity Capture-MS Mus musculus
42 CUL2 8453
Affinity Capture-MS Homo sapiens
43 SRPK3  
Affinity Capture-MS Homo sapiens
44 SND1 27044
Cross-Linking-MS (XL-MS) Homo sapiens
45 SP100 6672
Cross-Linking-MS (XL-MS) Homo sapiens
46 TXN2 25828
Cross-Linking-MS (XL-MS) Homo sapiens
47 CNBP 7555
Co-fractionation Homo sapiens
48 DST 667
Cross-Linking-MS (XL-MS) Homo sapiens
49 HIST1H2AD 3013
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
50 HSPA5 3309
Co-fractionation Homo sapiens
51 BRF1  
Affinity Capture-MS Homo sapiens
52 RBM39 9584
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
53 BLVRB 645
Cross-Linking-MS (XL-MS) Homo sapiens
54 MRTO4 51154
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 LMNB1 4001
Affinity Capture-MS Homo sapiens
56 APEH 327
Co-fractionation Homo sapiens
57 NMRAL1 57407
Cross-Linking-MS (XL-MS) Homo sapiens
58 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 EBNA1BP2 10969
Affinity Capture-MS Homo sapiens
60 ATAD3C 219293
Cross-Linking-MS (XL-MS) Homo sapiens
61 PAPD5 64282
Affinity Capture-MS Homo sapiens
62 EPRS 2058
Cross-Linking-MS (XL-MS) Homo sapiens
63 NIP7 51388
Affinity Capture-MS Homo sapiens
64 HIST1H1B 3009
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
65 PCBP1 5093
Proximity Label-MS Homo sapiens
66 RPA3 6119
Proximity Label-MS Homo sapiens
67 MYO9B 4650
Cross-Linking-MS (XL-MS) Homo sapiens
68 HIST1H1A 3024
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
69 PATZ1  
Affinity Capture-MS Homo sapiens
70 ZFP62  
Affinity Capture-MS Homo sapiens
71 HIST1H2AJ 8331
Cross-Linking-MS (XL-MS) Homo sapiens
72 COL17A1 1308
Co-fractionation Homo sapiens
73 PYHIN1  
Affinity Capture-MS Homo sapiens
74 YBX1 4904
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
75 RPS27A 6233
Cross-Linking-MS (XL-MS) Homo sapiens
76 PRDM10  
Affinity Capture-MS Homo sapiens
77 HIST1H2AC 8334
Cross-Linking-MS (XL-MS) Homo sapiens
78 RRS1 23212
Affinity Capture-MS Homo sapiens
79 RUVBL2 10856
Affinity Capture-MS Homo sapiens
80 HIST1H2BC 8347
Cross-Linking-MS (XL-MS) Homo sapiens
81 PUF60 22827
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
82 TAF1D  
Affinity Capture-MS Homo sapiens
83 KRR1 11103
Affinity Capture-MS Homo sapiens
84 LARP7 51574
Affinity Capture-MS Homo sapiens
85 NEIL1  
Affinity Capture-MS Homo sapiens
86 RPS24 6229
Affinity Capture-MS Homo sapiens
87 NCL 4691
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
88 HNRNPL 3191
Co-fractionation Homo sapiens
89 HIST1H2AB 8335
Cross-Linking-MS (XL-MS) Homo sapiens
90 PPAN 56342
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
91 PURA 5813
Affinity Capture-MS Homo sapiens
92 H1FOO 132243
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
93 DERL1 79139
Affinity Capture-MS Homo sapiens
94 CCNO  
Cross-Linking-MS (XL-MS) Homo sapiens
95 H1FNT  
Affinity Capture-MS Homo sapiens
96 SPRTN  
Affinity Capture-MS Homo sapiens
97 KIAA0020 9933
Affinity Capture-MS Homo sapiens
98 GJA1 2697
Affinity Capture-MS Homo sapiens
99 BTF3 689
Affinity Capture-MS Homo sapiens
100 VPRBP 9730
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
101 URB1 9875
Affinity Capture-MS Homo sapiens
102 HNRNPD 3184
Affinity Capture-MS Homo sapiens
103 URB2  
Affinity Capture-MS Homo sapiens
104 CAND1 55832
Affinity Capture-MS Homo sapiens
105 ASXL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
106 PWP2 5822
Affinity Capture-MS Homo sapiens
107 KDM2A  
Affinity Capture-MS Homo sapiens
108 RPS3 6188
Affinity Capture-MS Homo sapiens
109 DDX24 57062
Affinity Capture-MS Homo sapiens
110 H1FX 8971
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
111 PHLDA2 7262
Cross-Linking-MS (XL-MS) Homo sapiens
112 H2AFB3  
Affinity Capture-MS Homo sapiens
113 RRP12 23223
Affinity Capture-MS Homo sapiens
114 HIST2H3A 333932
Cross-Linking-MS (XL-MS) Homo sapiens
115 C8orf59  
Cross-Linking-MS (XL-MS) Homo sapiens
116 NPM1 4869
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
117 KRI1  
Affinity Capture-MS Homo sapiens
118 NSUN4  
Affinity Capture-MS Homo sapiens
119 FANCD2  
Affinity Capture-MS Homo sapiens
120 LEO1 123169
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
121 NSD1  
Biochemical Activity Homo sapiens
122 CUL1 8454
Affinity Capture-MS Homo sapiens
123 TBX1  
Cross-Linking-MS (XL-MS) Homo sapiens
124 ZNF184  
Affinity Capture-MS Homo sapiens
125 DHX36 170506
Affinity Capture-MS Homo sapiens
126 ZCRB1  
Affinity Capture-MS Homo sapiens
127 IRAK4 51135
Biochemical Activity Homo sapiens
128 HIST2H2AB 317772
Affinity Capture-MS Homo sapiens
129 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
130 DDX21 9188
Affinity Capture-MS Homo sapiens
131 RBX1 9978
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
132 WHSC1 7468
Affinity Capture-MS Homo sapiens
133 RPF2 84154
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
134 ATP2B1 490
Cross-Linking-MS (XL-MS) Homo sapiens
135 PSMD14 10213
Affinity Capture-MS Homo sapiens
136 ZBTB48  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
137 VRK1 7443
Affinity Capture-MS Homo sapiens
138 RPL35 11224
Affinity Capture-MS Homo sapiens
139 SAT2 112483
Affinity Capture-MS Homo sapiens
140 NCAPD3 23310
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
141 NELFE 7936
Affinity Capture-MS Homo sapiens
142 REXO4  
Affinity Capture-MS Homo sapiens
143 GAPDH 2597
Cross-Linking-MS (XL-MS) Homo sapiens
144 CTR9 9646
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
145 RPLP0 6175
Affinity Capture-MS Homo sapiens
146 DDX27 55661
Affinity Capture-MS Homo sapiens
147 SETD7 80854
Affinity Capture-MS Homo sapiens
148 CYLD  
Affinity Capture-MS Homo sapiens
149 G2E3  
Cross-Linking-MS (XL-MS) Homo sapiens
150 RSL1D1 26156
Affinity Capture-MS Homo sapiens
151 PPAN-P2RY11  
Affinity Capture-MS Homo sapiens
152 AIFM1 9131
Co-fractionation Homo sapiens
153 RPS2 6187
Affinity Capture-MS Homo sapiens
154 POP1 10940
Affinity Capture-MS Homo sapiens
155 IKZF3  
Affinity Capture-MS Homo sapiens
156 PRKAR2A 5576
Affinity Capture-MS Homo sapiens
157 SRSF5 6430
Affinity Capture-MS Homo sapiens
158 IKZF1  
Affinity Capture-MS Homo sapiens
159 HIST3H3 8290
Cross-Linking-MS (XL-MS) Homo sapiens
160 CEP250 11190
Affinity Capture-MS Homo sapiens
161 HIST1H2AH 85235
Cross-Linking-MS (XL-MS) Homo sapiens
162 MYC  
Affinity Capture-MS Homo sapiens
163 CEBPZ  
Affinity Capture-MS Homo sapiens
164 ZCCHC6 79670
Affinity Capture-MS Homo sapiens
165 CSNK2A2 1459
Two-hybrid Homo sapiens
166 WDR5 11091
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
167 DDB1 1642
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
168 RPL23A 6147
Cross-Linking-MS (XL-MS) Homo sapiens
169 FYTTD1  
Affinity Capture-MS Homo sapiens
170 NOP16 51491
Cross-Linking-MS (XL-MS) Homo sapiens
171 HIST1H1T 3010
Cross-Linking-MS (XL-MS) Homo sapiens
172 RPL26 6154
Affinity Capture-MS Homo sapiens
173 FTSJ3 117246
Affinity Capture-MS Homo sapiens
174 OAS3 4940
Affinity Capture-MS Homo sapiens
175 SETD4 54093
Affinity Capture-MS Homo sapiens
176 PARP1 142
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
177 TAF1A  
Affinity Capture-MS Homo sapiens
178 H3F3A 3020
Cross-Linking-MS (XL-MS) Homo sapiens
179 TP53 7157
Affinity Capture-MS Homo sapiens
180 FOLR1 2348
Affinity Capture-MS Homo sapiens
181 FXR1 8087
Cross-Linking-MS (XL-MS) Homo sapiens
182 UTP23  
Affinity Capture-MS Homo sapiens
183 RPS5 6193
Affinity Capture-MS Homo sapiens
184 PRKAR2B 5577
Affinity Capture-MS Homo sapiens
185 ESR1  
Affinity Capture-MS Homo sapiens
186 NOC2L 26155
Affinity Capture-MS Homo sapiens
187 DHFR 1719
Cross-Linking-MS (XL-MS) Homo sapiens
188 DENND4A 10260
Cross-Linking-MS (XL-MS) Homo sapiens
189 PRKCA 5578
Biochemical Activity Homo sapiens
190 GLYR1 84656
Affinity Capture-MS Homo sapiens
191 AEBP2  
Reconstituted Complex Homo sapiens
192 CKAP4 10970
Cross-Linking-MS (XL-MS) Homo sapiens
193 ZSCAN25  
Affinity Capture-MS Homo sapiens
194 CUL4A 8451
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
195 RALY 22913
Affinity Capture-MS Homo sapiens
196 NUPL2 11097
Affinity Capture-MS Homo sapiens
197 ABCA13  
Cross-Linking-MS (XL-MS) Homo sapiens
198 NEB 4703
Cross-Linking-MS (XL-MS) Homo sapiens
199 TANC1 85461
Cross-Linking-MS (XL-MS) Homo sapiens
200 CENPC  
Affinity Capture-MS Homo sapiens
201 LIMCH1 22998
Cross-Linking-MS (XL-MS) Homo sapiens
202 RPS19 6223
Affinity Capture-MS Homo sapiens
203 HNRNPCL1 343069
Affinity Capture-MS Homo sapiens
204 GTF2H2  
Affinity Capture-MS Homo sapiens
205 HIST2H2AA3 8337
Cross-Linking-MS (XL-MS) Homo sapiens
206 CAPZB 832
Affinity Capture-MS Homo sapiens
207 HEATR3 55027
Affinity Capture-MS Homo sapiens
208 TAOK3 51347
Cross-Linking-MS (XL-MS) Homo sapiens
209 MCM2 4171
Affinity Capture-MS Homo sapiens
210 IMP3 55272
Affinity Capture-MS Homo sapiens
211 MPHOSPH10 10199
Affinity Capture-MS Homo sapiens
212 ANOS1 3730
Affinity Capture-MS Homo sapiens
213 ITGA4 3676
Affinity Capture-MS Homo sapiens
214 ATRX 546
Affinity Capture-MS Homo sapiens
215 RPL29 6159
Cross-Linking-MS (XL-MS) Homo sapiens
216 DOT1L 84444
Affinity Capture-MS Homo sapiens
217 YAF2  
Affinity Capture-MS Homo sapiens
218 RBM19 9904
Affinity Capture-MS Homo sapiens
219 HSPA8 3312
Affinity Capture-MS Homo sapiens
220 LIN28A  
Affinity Capture-MS Homo sapiens
221 BRIX1 55299
Affinity Capture-MS Homo sapiens
222 EIF2AK2 5610
Affinity Capture-MS Homo sapiens
223 DDX31  
Affinity Capture-MS Homo sapiens
224 SCAF1  
Affinity Capture-MS Homo sapiens
225 RPS17 6218
Affinity Capture-MS Homo sapiens
226 ZCCHC9  
Cross-Linking-MS (XL-MS) Homo sapiens
227 UBE2T  
Cross-Linking-MS (XL-MS) Homo sapiens
228 CUL4B 8450
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
229 PARK2  
Affinity Capture-MS Homo sapiens
230 PHAX  
Co-fractionation Homo sapiens
231 RPS10 6204
Affinity Capture-MS Homo sapiens
232 XRN1 54464
Affinity Capture-MS Homo sapiens
233 BLM 641
Cross-Linking-MS (XL-MS) Homo sapiens
234 CAST 831
Co-fractionation Homo sapiens
235 NOP2 4839
Cross-Linking-MS (XL-MS) Homo sapiens
236 WDR61 80349
Affinity Capture-MS Homo sapiens
237 KPNA7  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
238 ABCF2 10061
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
239 RAN 5901
Co-fractionation Homo sapiens
240 RRM1 6240
Co-fractionation Homo sapiens
241 NTRK1 4914
Affinity Capture-MS Homo sapiens
242 HIST1H1E 3008
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
243 RPL37A 6168
Affinity Capture-MS Homo sapiens
244 HIST1H2BK 85236
Cross-Linking-MS (XL-MS) Homo sapiens
245 NECAP1 25977
Affinity Capture-MS Homo sapiens
246 HDAC5 10014
Affinity Capture-MS Homo sapiens
247 DNTTIP2  
Affinity Capture-MS Homo sapiens
248 PURB 5814
Affinity Capture-MS Homo sapiens
249 HIST1H2AI 8329
Cross-Linking-MS (XL-MS) Homo sapiens
250 TTN 7273
Cross-Linking-MS (XL-MS) Homo sapiens
251 HTR3A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
252 TONSL  
Affinity Capture-MS Homo sapiens
253 ZBTB2 57621
Affinity Capture-MS Homo sapiens
254 MRPL40 64976
Affinity Capture-MS Homo sapiens
255 KMT2A  
Cross-Linking-MS (XL-MS) Homo sapiens
256 CDC73  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
257 BAZ1B 9031
Affinity Capture-MS Homo sapiens
258 SEC24D 9871
Co-fractionation Homo sapiens
259 AHNAK 79026
Cross-Linking-MS (XL-MS) Homo sapiens
260 TTLL1  
Cross-Linking-MS (XL-MS) Homo sapiens
261 SF1 7536
Cross-Linking-MS (XL-MS) Homo sapiens
262 DCAF13 25879
Cross-Linking-MS (XL-MS) Homo sapiens
263 MARCO  
Cross-Linking-MS (XL-MS) Homo sapiens
264 H1F0 3005
Cross-Linking-MS (XL-MS) Homo sapiens
265 ACE2 59272
Affinity Capture-MS Homo sapiens
266 PDCD11 22984
Affinity Capture-MS Homo sapiens
267 POLR2A 5430
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
268 LMOD1 25802
Cross-Linking-MS (XL-MS) Homo sapiens
269 ASB16 92591
Affinity Capture-MS Homo sapiens
270 DGKZ  
Affinity Capture-MS Homo sapiens
271 PHF6  
Affinity Capture-MS Homo sapiens
272 YWHAQ 10971
Affinity Capture-MS Homo sapiens
273 TOP1 7150
Affinity Capture-MS Homo sapiens
274 RPA4  
Proximity Label-MS Homo sapiens
275 RPL22 6146
Cross-Linking-MS (XL-MS) Homo sapiens
276 RPL18 6141
Cross-Linking-MS (XL-MS) Homo sapiens
277 RNF2  
Affinity Capture-MS Homo sapiens
278 ZC3HAV1 56829
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
279 NTSR1  
Affinity Capture-MS Homo sapiens
280 AKAP1 8165
Affinity Capture-MS Homo sapiens
281 ILF3 3609
Affinity Capture-MS Homo sapiens
282 C3orf17  
Affinity Capture-MS Homo sapiens
283 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
284 NME8  
Cross-Linking-MS (XL-MS) Homo sapiens
285 RPL6 6128
Cross-Linking-MS (XL-MS) Homo sapiens
286 PRDM15  
Affinity Capture-MS Homo sapiens
287 MCM5 4174
Affinity Capture-MS Homo sapiens
288 MRPL53  
Affinity Capture-MS Homo sapiens
289 ALDH1B1 219
Co-fractionation Homo sapiens
290 WRAP73 49856
Affinity Capture-MS Homo sapiens
291 CENPO  
Affinity Capture-MS Homo sapiens
292 C10orf11  
Cross-Linking-MS (XL-MS) Homo sapiens
293 TRIM37  
Proximity Label-MS Homo sapiens
294 IL17B 27190
Affinity Capture-MS Homo sapiens
295 FLNA 2316
Cross-Linking-MS (XL-MS) Homo sapiens
296 RPL8 6132
Cross-Linking-MS (XL-MS) Homo sapiens
297 C14orf166 51637
Cross-Linking-MS (XL-MS) Homo sapiens
298 RPL28 6158
Affinity Capture-MS Homo sapiens
299 SERBP1 26135
Affinity Capture-MS Homo sapiens
300 RC3H1 149041
Affinity Capture-MS Homo sapiens
301 HMGB2 3148
Cross-Linking-MS (XL-MS) Homo sapiens
302 NUCKS1 64710
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
303 KIF4A 24137
Cross-Linking-MS (XL-MS) Homo sapiens
304 UBA52 7311
Cross-Linking-MS (XL-MS) Homo sapiens
305 RPL11 6135
Affinity Capture-MS Homo sapiens
306 IGF2BP1 10642
Cross-Linking-MS (XL-MS) Homo sapiens
307 RPS3A 6189
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
308 CPOX 1371
Co-fractionation Homo sapiens
309 RPL30 6156
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
310 IPO7 10527
Affinity Capture-MS Homo sapiens
311 NOP9 161424
Affinity Capture-MS Homo sapiens
312 LRRC16A 55604
Cross-Linking-MS (XL-MS) Homo sapiens
313 HIST1H1D 3007
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
314 RPL13A 23521
Cross-Linking-MS (XL-MS) Homo sapiens
315 KPNB1 3837
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
316 DHX57 90957
Affinity Capture-MS Homo sapiens
317 CCDC124 115098
Cross-Linking-MS (XL-MS) Homo sapiens
318 APP 351
Reconstituted Complex Homo sapiens
319 USP36  
Affinity Capture-MS Homo sapiens
320 COPS5 10987
Affinity Capture-MS Homo sapiens
321 RPS20 6224
Cross-Linking-MS (XL-MS) Homo sapiens
322 PRC1 9055
Affinity Capture-MS Homo sapiens
323 PLK4  
Affinity Capture-MS Homo sapiens
324 RPL24 6152
Cross-Linking-MS (XL-MS) Homo sapiens
325 WDR12 55759
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
326 HMX2  
Cross-Linking-MS (XL-MS) Homo sapiens
327 HMGA1 3159
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
328 ABCE1 6059
Affinity Capture-MS Homo sapiens
329 ZCCHC3  
Affinity Capture-MS Homo sapiens
330 PRKRA 8575
Affinity Capture-MS Homo sapiens
331 MAP2K1 5604
Cross-Linking-MS (XL-MS) Homo sapiens
332 EED  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
333 SRP68 6730
Affinity Capture-MS Homo sapiens
334 NOC3L 64318
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
335 RRP8  
Affinity Capture-MS Homo sapiens
336 METTL14  
Affinity Capture-MS Homo sapiens
337 SLC4A1AP  
Cross-Linking-MS (XL-MS) Homo sapiens
338 MYCN  
Affinity Capture-MS Homo sapiens
339 MAK16  
Affinity Capture-MS Homo sapiens
340 H2AFZ 3015
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
341 FARS2 10667
Affinity Capture-MS Homo sapiens
342 PRPF6 24148
Cross-Linking-MS (XL-MS) Homo sapiens
343 HMGN2 3151
Cross-Linking-MS (XL-MS) Homo sapiens
344 STAU1 6780
Affinity Capture-MS Homo sapiens
345 ABT1 29777
Affinity Capture-MS Homo sapiens
346 RAD51  
Affinity Capture-MS Homo sapiens
347 RNF146  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
348 ZNF22  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
349 RNF168  
Reconstituted Complex Homo sapiens
350 IFI16 3428
Affinity Capture-MS Homo sapiens
351 DCTN1 1639
Cross-Linking-MS (XL-MS) Homo sapiens
352 DDX54 79039
Affinity Capture-MS Homo sapiens
353 PML 5371
Affinity Capture-MS Homo sapiens
354 CCDC7  
Cross-Linking-MS (XL-MS) Homo sapiens
355 RAD54L2  
Cross-Linking-MS (XL-MS) Homo sapiens
356 H2AFY 9555
Affinity Capture-MS Homo sapiens
357 CEBPA  
Protein-peptide Homo sapiens
358 PRKACB 5567
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
359 DAXX  
Affinity Capture-MS Homo sapiens
360 RPF1  
Affinity Capture-MS Homo sapiens
361 CENPI  
Affinity Capture-MS Homo sapiens
362 BMS1  
Affinity Capture-MS Homo sapiens
363 PRPF4B 8899
Affinity Capture-MS Homo sapiens
364 HIST1H3A 8350
Co-localization Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
365 NR4A1  
Affinity Capture-MS Homo sapiens
366 GLE1 2733
Affinity Capture-MS Homo sapiens
367 NELFCD 51497
Affinity Capture-MS Homo sapiens
368 HIST2H2BF 440689
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
369 NAT10 55226
Affinity Capture-MS Homo sapiens
370 CTNNB1 1499
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
371 MYL1 4632
Cross-Linking-MS (XL-MS) Homo sapiens
372 RPL3 6122
Affinity Capture-MS Homo sapiens
373 THOC5 8563
Co-fractionation Homo sapiens
374 PRG4 10216
Cross-Linking-MS (XL-MS) Homo sapiens
375 SUZ12  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
376 TBCD 6904
Co-fractionation Homo sapiens
377 NXF2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
378 IL7R  
Protein-RNA Homo sapiens
379 DKC1 1736
Affinity Capture-MS Homo sapiens
380 AKAP5  
Cross-Linking-MS (XL-MS) Homo sapiens
381 PRDM13 59336
Affinity Capture-MS Homo sapiens
382 FIP1L1 81608
Co-fractionation Homo sapiens
383 BMP4 652
Affinity Capture-MS Homo sapiens
384 ZC3H3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
385 FARP1 10160
Affinity Capture-MS Homo sapiens
386 TRIM71  
Affinity Capture-MS Homo sapiens
387 H2AFX 3014
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
388 YTHDC2 64848
Affinity Capture-MS Homo sapiens
389 SNCA 6622
Reconstituted Complex Homo sapiens
390 ARRB2 409
Affinity Capture-MS Homo sapiens
391 SRRM1 10250
Cross-Linking-MS (XL-MS) Homo sapiens
392 INPPL1 3636
Cross-Linking-MS (XL-MS) Homo sapiens
393 NOL10  
Affinity Capture-MS Homo sapiens
394 MNDA 4332
Cross-Linking-MS (XL-MS) Homo sapiens
395 ZNF746  
Affinity Capture-MS Homo sapiens
396 CUL5 8065
Affinity Capture-MS Homo sapiens
397 SMURF1 57154
Affinity Capture-MS Homo sapiens
398 RPS15 6209
Affinity Capture-MS Homo sapiens
399 HIST1H2BD 3017
Cross-Linking-MS (XL-MS) Homo sapiens
400 HDGF 3068
Affinity Capture-MS Homo sapiens
401 MOV10 4343
Affinity Capture-MS Homo sapiens
402 ARRB1 408
Affinity Capture-MS Homo sapiens
403 PYGB 5834
Co-fractionation Homo sapiens
404 TRIM31  
Affinity Capture-MS Homo sapiens
405 LENEP  
Affinity Capture-MS Homo sapiens
406 C9orf72  
Affinity Capture-MS Homo sapiens
407 PAF1 54623
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
408 TRIM29 23650
Affinity Capture-MS Homo sapiens
409 NEDD8 4738
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here