Gene description for DNAJC3
Gene name
DnaJ (Hsp40) homolog, subfamily C, member 3
Gene symbol
DNAJC3
Other names/aliases
ACPHD ERdj6 HP58 P58 P58IPK PRKRI
Species
Homo sapiens
Database cross references - DNAJC3
ExoCarta
ExoCarta_5611
Entrez Gene
5611
HGNC
9439
MIM
601184
UniProt
Q13217
DNAJC3 identified in exosomes derived from the following tissue/cell type
Saliva
19199708
Squamous carcinoma cells
20124223
Gene ontology annotations for DNAJC3
Experiment description of studies that identified DNAJC3 in exosomes
1
Experiment ID
66
ISEV standards
✔
IEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
CD63|CD81
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
19199708
Organism
Homo sapiens
Experiment description
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors
Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal name
JPR
Publication year
2009
Sample
Saliva
Sample name
Saliva
Isolation/purification methods
Differential centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [LTQ] Western blotting Immunoelectron Microscopy
2
Experiment ID
191
ISEV standards
✘
EV Biophysical techniques
✔
Alix
EV Cytosolic markers
✔
CD81|CD9
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
20124223
Organism
Homo sapiens
Experiment description
Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors
Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name
Mol Cell Proteomics
Publication year
2010
Sample
Squamous carcinoma cells
Sample name
Squamous carcinoma cell (A431)
Isolation/purification methods
Differential centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for DNAJC3
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
EIF2AK3
Affinity Capture-Western
Homo sapiens
Phenotypic Suppression
Homo sapiens
Reconstituted Complex
Homo sapiens
Affinity Capture-Western
Homo sapiens
2
PRKRIR
Invivo
Homo sapiens
Invitro
Homo sapiens
Two-hybrid
Homo sapiens
Affinity Capture-MS
Homo sapiens
3
DNAJB1
3337
Invitro
Homo sapiens
Two-hybrid
Homo sapiens
Affinity Capture-MS
Homo sapiens
4
EIF2AK2
5610
Reconstituted Complex
Homo sapiens
5
HSPA4
3308
Invitro
Homo sapiens
Two-hybrid
Homo sapiens
View the network
image/svg+xml
Pathways in which DNAJC3 is involved