Gene description for PXN
Gene name	paxillin
Gene symbol	PXN
Other names/aliases	-
Species	Homo sapiens
Database cross references - PXN
ExoCarta	ExoCarta_5829
Entrez Gene	5829
HGNC	9718
MIM	602505
UniProt	P49023
PXN identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927

Gene ontology annotations for PXN

Molecular Function     protein binding GO:0005515 IPI     protein kinase binding GO:0019901 IEA     zinc ion binding GO:0008270 IEA     BH4 domain binding GO:0051435 IEA     beta-catenin binding GO:0008013 IPI     vinculin binding GO:0017166 IPI     integrin binding GO:0005178 IEA Biological Process     branching morphogenesis of an epithelial tube GO:0048754 IEA     lamellipodium assembly GO:0030032 IEA     vascular endothelial growth factor receptor signaling pathway GO:0048010 TAS     focal adhesion assembly GO:0048041 IEA     activation of MAPK activity GO:0000187 IEA     cellular response to reactive oxygen species GO:0034614 IEP     muscle contraction GO:0006936 TAS     substrate adhesion-dependent cell spreading GO:0034446 IEA     regulation of cell shape GO:0008360 IEA     cell junction assembly GO:0034329 TAS     transforming growth factor beta receptor signaling pathway GO:0007179 IDA     peptidyl-tyrosine phosphorylation GO:0018108 IEA     signal complex assembly GO:0007172 TAS     epidermal growth factor receptor signaling pathway GO:0007173 TAS     signal transduction GO:0007165 TAS     growth hormone receptor signaling pathway GO:0060396 IDA     cytoskeleton organization GO:0007010 IEA     cell adhesion GO:0007155 NAS     integrin-mediated signaling pathway GO:0007229 IEA Subcellular Localization     microtubule associated complex GO:0005875 TAS     lamellipodium GO:0030027 IDA     stress fiber GO:0001725 IDA     focal adhesion GO:0005925 IDA     cytosol GO:0005829 TAS     nucleoplasm GO:0005654 IDA     cytoplasm GO:0005737 IDA     cell cortex GO:0005938 IEA     plasma membrane GO:0005886 TAS