HP1BP3 
                                                                        
                                                                            
                                                                                
                                                                         
                                                                     
                                                            
                                                            
                                                         
                                                        
                                                        
                                                            
                                                                HP1BP3  in sEVs
                                                                                
                                                                                    
                                                                                        
                                                                                            1 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        489 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                EM
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                Canx
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            36408942
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Rattus norvegicus 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Proteomics 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2023 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Bone marrow mesenchymal stem cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        BMSC - Passage 6 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Western blotting 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            2 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        490 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                EM
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                Canx
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            36408942
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Rattus norvegicus 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Proteomics 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2023 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Bone marrow mesenchymal stem cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        BMSC - Passage 7 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Western blotting 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            3 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        491 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                EM
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                Canx
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            36408942
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Rattus norvegicus 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Proteomics 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2023 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Bone marrow mesenchymal stem cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        BMSC - Passage 8 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Western blotting 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            4 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        492 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                EM
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                Canx
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            36408942
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Rattus norvegicus 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Proteomics 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2023 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Bone marrow mesenchymal stem cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        BMSC - Passage 9 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Western blotting 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            5 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        412 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                EM
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CANX|ACTB
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            34108659
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Nat Cell Biol 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Breast cancer cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        MCF7 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        RT-qPCR 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            6 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        414 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                EM
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CANX
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            34108659
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Nat Cell Biol 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Breast cancer cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        MDA-MB-231 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        RT-qPCR 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            7 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        426 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CANX
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            34108659
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Nat Cell Biol 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Breast cancer cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        MDA-MB-231  - Exo-rich fractions 7-10 pooled 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Western blotting 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            8 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        427 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CANX
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            34108659
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Nat Cell Biol 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Breast cancer cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        MDA-MB-231 - Exo-rich fractions 1-6 pooled 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Mass spectrometry 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            9 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        497 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            35931686
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Varela-EirÃÂn M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, GarcÃÂa-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Cell Death Dis 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2022 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Chondrocytes 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        T/C-28a2 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Western blotting 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            10 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        498 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                EM
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            35931686
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Varela-EirÃÂn M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, GarcÃÂa-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Cell Death Dis 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2022 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Chondrocytes 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        T/C-28a2 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Western blotting 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            11 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        207 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                EM
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                TSG101|HSP70|FLOT1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                VDAC
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            protein
                                                                                                                                                                                                                                     
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            23161513
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Mol Cell Proteomics 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2012 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Colorectal cancer cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        DKO-1 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Mass spectrometry 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            12 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        208 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                EM
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                TSG101|HSP70|FLOT1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                VDAC
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            protein
                                                                                                                                                                                                                                     
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            23161513
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Mol Cell Proteomics 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2012 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Colorectal cancer cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        Dks-8 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Mass spectrometry 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            13 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        209 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                TSG101|HSP70|FLOT1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                VDAC
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            protein
                                                                                                                                                                                                                                     
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            23161513
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Mol Cell Proteomics 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2012 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Colorectal cancer cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        DLD-1 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Mass spectrometry 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            14 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        407 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                EM
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CANX
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            34108659
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Nat Cell Biol 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Embryonic kidney cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        HEK293T 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        RT-qPCR 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            15 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        419 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CANX
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            34108659
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Nat Cell Biol 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Embryonic kidney cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        HEK293T - Exo-rich fractions 7-10 pooled 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Western blotting 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            16 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        419 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CANX
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            34108659
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Nat Cell Biol 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Embryonic kidney cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        HEK293T - Exo-rich fractions 7-10 pooled 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Western blotting 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            17 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        420 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CANX
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            34108659
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Nat Cell Biol 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Embryonic kidney cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        HEK293T - Exo-rich fractions 1-6 pooled 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Mass spectrometry 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            18 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        420 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CANX
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            34108659
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Nat Cell Biol 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Embryonic kidney cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        HEK293T - Exo-rich fractions 1-6 pooled 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Mass spectrometry 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            19 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        405 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                EM
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CANX
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            34108659
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Nat Cell Biol 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Foreskin fibroblasts 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        BJ  
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        RT-qPCR 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            20 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        363 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                DCLK1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            33991177
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Proteomics 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Gastric cancer cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        MKN1 - 100K pellet 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Western blotting 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            21 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        364 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                DCLK1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            33991177
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Proteomics 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Gastric cancer cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        MKN1 - 100K pellet 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Western blotting 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            22 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        365 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                DCLK1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            33991177
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Proteomics 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Gastric cancer cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        MKN1 - 100K pellet 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Western blotting 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            23 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        417 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                EM
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CANX|ACTB
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            34108659
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Nat Cell Biol 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Lymphoma cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        Raji 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        RT-qPCR 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            24 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        411 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                EM
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CANX
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            34108659
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Nat Cell Biol 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Mammary cancer-associated fibroblasts 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        mCAF 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        RT-qPCR 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            25 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        488 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                EM
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CANX
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            36408942
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Proteomics 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2023 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Mesenchymal stem cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        UCMSC 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Western blotting 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            26 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        418 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                EM
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CANX
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            34108659
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Nat Cell Biol 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Monocytic leukemia cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        THP-1 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        RT-qPCR 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            27 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        418 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                EM
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CANX
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            34108659
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Nat Cell Biol 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Monocytic leukemia cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        THP-1 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        RT-qPCR 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            28 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        413 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                EM
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CANX
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            34108659
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Nat Cell Biol 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Normal mammary epithelial cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        MCF10A 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        RT-qPCR 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            29 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        211 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                EM
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                TSG101|Alix|EpCAM|TFRC
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                cytochrome c|GOLGA2
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            protein
                                                                                                                                                                                                                                     
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            23333927
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Characterization and proteomic analysis of ovarian cancer-derived exosomes. 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            J Proteomics 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2013 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Ovarian cancer cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        IGROV1 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        1.09-1.15 g/mL
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Mass spectrometry 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            30 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        212 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CEM
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                TSG101|Alix|EpCAM|TFRC
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                Cytochrome C|GOLGA2
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            protein
                                                                                                                                                                                                                                     
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            23333927
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Characterization and proteomic analysis of ovarian cancer-derived exosomes. 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            J Proteomics 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2013 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Ovarian cancer cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        OVCAR-3 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        1.09-1.15 g/mL
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Mass spectrometry 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            31 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        406 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                EM
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CANX
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            34108659
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Nat Cell Biol 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Pancreatic cancer cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        BxPC3 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        RT-qPCR 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            32 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        415 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                EM
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CANX
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            34108659
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Nat Cell Biol 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Pancreatic cancer cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        PANC-1 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        RT-qPCR 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            33 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        434 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CANX
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            34108659
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Nat Cell Biol 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Pancreatic cancer cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        PANC-1  - Exo-rich fractions 7-10 pooled 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Western blotting 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            34 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        435 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CANX
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            34108659
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Nat Cell Biol 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Pancreatic cancer cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        PANC-1 - Exo-rich fractions 1-6 pooled 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Mass spectrometry 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            35 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        408 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                EM
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CANX|ACTB
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            34108659
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Nat Cell Biol 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Pancreatic duct epithalial cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        HPDE 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        RT-qPCR 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            36 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        409 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                EM
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CANX
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            34108659
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Nat Cell Biol 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Pancreatic duct epithalial cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        HPNE 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        RT-qPCR 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            37 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        416 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                EM
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CANX
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            34108659
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Nat Cell Biol 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Pluripotent stem cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        PSC 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        RT-qPCR 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            38 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        410 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                EM
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                CANX
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            34108659
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Nat Cell Biol 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        T lymphocytes 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        Jurkat 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        RT-qPCR 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            39 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        217 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                EM
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                TSG101|CD81|CD9|CD63
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            protein
                                                                                                                                                                                                                                     
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            23844026
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Characterization of human thymic exosomes. 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            PLoS One 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2013 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Thymus 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        Normal-Thymus 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Mass spectrometry 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                
                                                         
                                                        
                                                        
                                                        
                                                            
                                                                
                                                                    
                                                                        
                                                                            HP1BP3 
                                                                                
                                                                                    
                                                                                        
                                                                                              
                                                                                            Protein Interactor 
                                                                                            ExoCarta ID 
                                                                                            Identification method 
                                                                                            PubMed 
                                                                                            Species 
                                                                                         
                                                                                                                                                                                    
                                                                                                
                                                                                                    1 
                                                                                                                                                                                                                UBE2H 
                                                                                                            7328 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    2 
                                                                                                                                                                                                            DGCR8 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    3 
                                                                                                                                                                                                                HIST2H2BE 
                                                                                                            8349 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    4 
                                                                                                                                                                                                                ISG15 
                                                                                                            9636 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    5 
                                                                                                                                                                                                            H1FNT 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    6 
                                                                                                                                                                                                                RSL1D1 
                                                                                                            26156 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                        Co-fractionation 
                                                                                                                                        Homo sapiens 
                                                                                                                                                                                                                                                             
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    7 
                                                                                                                                                                                                                UTP14A 
                                                                                                            10813 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    8 
                                                                                                                                                                                                            ARHGEF19 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    9 
                                                                                                                                                                                                                CNBP 
                                                                                                            7555 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    10 
                                                                                                                                                                                                            PAXIP1 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    11 
                                                                                                                                                                                                            ZNF346 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                        Affinity Capture-MS 
                                                                                                                                        Homo sapiens 
                                                                                                                                                                                                                                                             
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    12 
                                                                                                                                                                                                                FGD2 
                                                                                                            221472 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    13 
                                                                                                                                                                                                                RPL4 
                                                                                                            6124 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    14 
                                                                                                                                                                                                                RPS4X 
                                                                                                            6191 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Cross-Linking-MS (XL-MS) 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    15 
                                                                                                                                                                                                                KIAA0020 
                                                                                                            9933 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    16 
                                                                                                                                                                                                                IPO7 
                                                                                                            10527 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                        Affinity Capture-MS 
                                                                                                                                        Homo sapiens 
                                                                                                                                                                                                                                                             
                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                        Affinity Capture-MS 
                                                                                                                                        Homo sapiens 
                                                                                                                                                                                                                                                             
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    17 
                                                                                                                                                                                                                SRPK2 
                                                                                                            6733 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    18 
                                                                                                                                                                                                            FGD1 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    19 
                                                                                                                                                                                                                RPL13A 
                                                                                                            23521 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    20 
                                                                                                                                                                                                            FBXO25 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Biochemical Activity 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    21 
                                                                                                                                                                                                                ZNF326 
                                                                                                            284695 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    22 
                                                                                                                                                                                                                RPS19 
                                                                                                            6223 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    23 
                                                                                                                                                                                                                RPL10 
                                                                                                            6134 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    24 
                                                                                                                                                                                                                LSM4 
                                                                                                            25804 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Cross-Linking-MS (XL-MS) 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    25 
                                                                                                                                                                                                            BRD2 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    26 
                                                                                                                                                                                                                RPL14 
                                                                                                            9045 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    27 
                                                                                                                                                                                                                CSNK2A1 
                                                                                                            1457 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    28 
                                                                                                                                                                                                            PNMAL1 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    29 
                                                                                                                                                                                                                CAND1 
                                                                                                            55832 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    30 
                                                                                                                                                                                                                KPNB1 
                                                                                                            3837 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                        Affinity Capture-MS 
                                                                                                                                        Homo sapiens 
                                                                                                                                                                                                                                                             
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    31 
                                                                                                                                                                                                                APP 
                                                                                                            351 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                        Reconstituted Complex 
                                                                                                                                        Homo sapiens 
                                                                                                                                                                                                                                                             
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Reconstituted Complex 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    32 
                                                                                                                                                                                                                HIST1H2BC 
                                                                                                            8347 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Cross-Linking-MS (XL-MS) 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    33 
                                                                                                                                                                                                            CENPA 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Proximity Label-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    34 
                                                                                                                                                                                                                APEX1 
                                                                                                            328 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Proximity Label-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    35 
                                                                                                                                                                                                                RPS9 
                                                                                                            6203 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    36 
                                                                                                                                                                                                            CBX6 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    37 
                                                                                                                                                                                                                GPATCH4 
                                                                                                            54865 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    38 
                                                                                                                                                                                                                HIST1H1A 
                                                                                                            3024 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                        Affinity Capture-MS 
                                                                                                                                        Homo sapiens 
                                                                                                                                                                                                                                                             
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    39 
                                                                                                                                                                                                            PRR11 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                        Affinity Capture-MS 
                                                                                                                                        Homo sapiens 
                                                                                                                                                                                                                                                             
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    40 
                                                                                                                                                                                                                DDI2 
                                                                                                            84301 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                        Affinity Capture-MS 
                                                                                                                                        Homo sapiens 
                                                                                                                                                                                                                                                             
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    41 
                                                                                                                                                                                                            LLPH 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    42 
                                                                                                                                                                                                                G3BP2 
                                                                                                            9908 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    43 
                                                                                                                                                                                                            H2AFB3 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    44 
                                                                                                                                                                                                            CCDC137 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    45 
                                                                                                                                                                                                            FBXW7 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    46 
                                                                                                                                                                                                                PRC1 
                                                                                                            9055 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    47 
                                                                                                                                                                                                            BHLHA15 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    48 
                                                                                                                                                                                                                NPM1 
                                                                                                            4869 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                        Affinity Capture-MS 
                                                                                                                                        Homo sapiens 
                                                                                                                                                                                                                                                             
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    49 
                                                                                                                                                                                                            KLF15 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    50 
                                                                                                                                                                                                                OBSL1 
                                                                                                            23363 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    51 
                                                                                                                                                                                                                HMGA1 
                                                                                                            3159 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    52 
                                                                                                                                                                                                                SRP14 
                                                                                                            6727 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    53 
                                                                                                                                                                                                                HNRNPU 
                                                                                                            3192 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    54 
                                                                                                                                                                                                                IPO8 
                                                                                                            10526 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                        Affinity Capture-MS 
                                                                                                                                        Homo sapiens 
                                                                                                                                                                                                                                                             
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    55 
                                                                                                                                                                                                                PRKRA 
                                                                                                            8575 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    56 
                                                                                                                                                                                                                YBX2 
                                                                                                            51087 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    57 
                                                                                                                                                                                                                ITGA4 
                                                                                                            3676 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    58 
                                                                                                                                                                                                                ZC3HAV1 
                                                                                                            56829 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                        Affinity Capture-MS 
                                                                                                                                        Homo sapiens 
                                                                                                                                                                                                                                                             
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    59 
                                                                                                                                                                                                                NUSAP1 
                                                                                                            51203 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    60 
                                                                                                                                                                                                                MECP2 
                                                                                                            4204 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    61 
                                                                                                                                                                                                                Eif3a 
                                                                                                            13669 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Mus musculus 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    62 
                                                                                                                                                                                                                CUL1 
                                                                                                            8454 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    63 
                                                                                                                                                                                                            MYCN 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    64 
                                                                                                                                                                                                                MAPRE1 
                                                                                                            22919 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    65 
                                                                                                                                                                                                                OASL 
                                                                                                            8638 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    66 
                                                                                                                                                                                                            MAK16 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    67 
                                                                                                                                                                                                                RRP7A 
                                                                                                            27341 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    68 
                                                                                                                                                                                                                RBM14 
                                                                                                            10432 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    69 
                                                                                                                                                                                                                KIF14 
                                                                                                            9928 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    70 
                                                                                                                                                                                                            LIN28A 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                        Affinity Capture-MS 
                                                                                                                                        Homo sapiens 
                                                                                                                                                                                                                                                             
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-Western 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    71 
                                                                                                                                                                                                            EMC9 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    72 
                                                                                                                                                                                                            KLF16 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    73 
                                                                                                                                                                                                            E2F4 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    74 
                                                                                                                                                                                                                H2AFZ 
                                                                                                            3015 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    75 
                                                                                                                                                                                                            BRPF1 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Cross-Linking-MS (XL-MS) 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    76 
                                                                                                                                                                                                                SRP9 
                                                                                                            6726 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    77 
                                                                                                                                                                                                                RPL30 
                                                                                                            6156 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                        Affinity Capture-MS 
                                                                                                                                        Homo sapiens 
                                                                                                                                                                                                                                                             
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    78 
                                                                                                                                                                                                            FOXA1 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    79 
                                                                                                                                                                                                            HMG20A 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    80 
                                                                                                                                                                                                                HIST1H4A 
                                                                                                            8359 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    81 
                                                                                                                                                                                                                DDX21 
                                                                                                            9188 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    82 
                                                                                                                                                                                                            PARK2 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    83 
                                                                                                                                                                                                                WHSC1 
                                                                                                            7468 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Proximity Label-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    84 
                                                                                                                                                                                                            TARBP2 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                        Affinity Capture-MS 
                                                                                                                                        Homo sapiens 
                                                                                                                                                                                                                                                             
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-Western 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    85 
                                                                                                                                                                                                            ZBTB47 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    86 
                                                                                                                                                                                                                LARP7 
                                                                                                            51574 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    87 
                                                                                                                                                                                                            C17orf85 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    88 
                                                                                                                                                                                                                ADARB1 
                                                                                                            104 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    89 
                                                                                                                                                                                                            REXO4 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    90 
                                                                                                                                                                                                                APOBEC3C 
                                                                                                            27350 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    91 
                                                                                                                                                                                                                SRSF6 
                                                                                                            6431 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    92 
                                                                                                                                                                                                                NOP2 
                                                                                                            4839 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    93 
                                                                                                                                                                                                                CBX3 
                                                                                                            11335 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Proximity Label-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    94 
                                                                                                                                                                                                                VRK1 
                                                                                                            7443 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    95 
                                                                                                                                                                                                                RPL5 
                                                                                                            6125 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                        Affinity Capture-MS 
                                                                                                                                        Homo sapiens 
                                                                                                                                                                                                                                                             
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    96 
                                                                                                                                                                                                                RPL35 
                                                                                                            11224 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    97 
                                                                                                                                                                                                            Srp72 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Mus musculus 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    98 
                                                                                                                                                                                                            PCDHA2 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    99 
                                                                                                                                                                                                                BARD1 
                                                                                                            580 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    100 
                                                                                                                                                                                                                NTRK1 
                                                                                                            4914 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    101 
                                                                                                                                                                                                                IFI16 
                                                                                                            3428 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    102 
                                                                                                                                                                                                                HIST1H1E 
                                                                                                            3008 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Cross-Linking-MS (XL-MS) 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    103 
                                                                                                                                                                                                            RAD18 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    104 
                                                                                                                                                                                                                SUMO2 
                                                                                                            6613 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Reconstituted Complex 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    105 
                                                                                                                                                                                                                PARP1 
                                                                                                            142 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    106 
                                                                                                                                                                                                                NFIA 
                                                                                                            4774 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    107 
                                                                                                                                                                                                            MEOX2 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Two-hybrid 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    108 
                                                                                                                                                                                                                HIST2H2AC 
                                                                                                            8338 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    109 
                                                                                                                                                                                                            TRIM11 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    110 
                                                                                                                                                                                                                HIST1H2BG 
                                                                                                            8339 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Proximity Label-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    111 
                                                                                                                                                                                                                PML 
                                                                                                            5371 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    112 
                                                                                                                                                                                                                ANAPC4 
                                                                                                            29945 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    113 
                                                                                                                                                                                                                HECTD1 
                                                                                                            25831 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    114 
                                                                                                                                                                                                                RPLP0 
                                                                                                            6175 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    115 
                                                                                                                                                                                                            EED 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    116 
                                                                                                                                                                                                                MAGEB2 
                                                                                                            4113 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    117 
                                                                                                                                                                                                                MYBBP1A 
                                                                                                            10514 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    118 
                                                                                                                                                                                                            KLF12 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    119 
                                                                                                                                                                                                                NIPSNAP1 
                                                                                                            8508 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    120 
                                                                                                                                                                                                            FGF13 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    121 
                                                                                                                                                                                                            DAXX 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    122 
                                                                                                                                                                                                                MRPL2 
                                                                                                            51069 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    123 
                                                                                                                                                                                                                RPL11 
                                                                                                            6135 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    124 
                                                                                                                                                                                                            WDR46 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                        Affinity Capture-MS 
                                                                                                                                        Homo sapiens 
                                                                                                                                                                                                                                                             
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    125 
                                                                                                                                                                                                            SCARNA22 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-RNA 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    126 
                                                                                                                                                                                                                ANLN 
                                                                                                            54443 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    127 
                                                                                                                                                                                                                FGFBP1 
                                                                                                            9982 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    128 
                                                                                                                                                                                                                NUMA1 
                                                                                                            4926 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    129 
                                                                                                                                                                                                            PKMYT1 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    130 
                                                                                                                                                                                                                OGT 
                                                                                                            8473 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Reconstituted Complex 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    131 
                                                                                                                                                                                                                KRT3 
                                                                                                            3850 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    132 
                                                                                                                                                                                                                HIST1H3A 
                                                                                                            8350 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Proximity Label-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    133 
                                                                                                                                                                                                            FANCD2 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    134 
                                                                                                                                                                                                                SURF4 
                                                                                                            6836 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    135 
                                                                                                                                                                                                                RPS24 
                                                                                                            6229 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    136 
                                                                                                                                                                                                                SRSF7 
                                                                                                            6432 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    137 
                                                                                                                                                                                                                TMPO 
                                                                                                            7112 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    138 
                                                                                                                                                                                                                RPL13 
                                                                                                            6137 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    139 
                                                                                                                                                                                                                XPO1 
                                                                                                            7514 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    140 
                                                                                                                                                                                                                LMNB1 
                                                                                                            4001 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                        Proximity Label-MS 
                                                                                                                                        Homo sapiens 
                                                                                                                                                                                                                                                             
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    141 
                                                                                                                                                                                                                HSPE1 
                                                                                                            3336 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Cross-Linking-MS (XL-MS) 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    142 
                                                                                                                                                                                                            SIRT7 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    143 
                                                                                                                                                                                                                SRSF4 
                                                                                                            6429 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    144 
                                                                                                                                                                                                                NPM3 
                                                                                                            10360 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    145 
                                                                                                                                                                                                            USP36 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    146 
                                                                                                                                                                                                                CUL3 
                                                                                                            8452 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    147 
                                                                                                                                                                                                                RPS6 
                                                                                                            6194 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    148 
                                                                                                                                                                                                                SRSF5 
                                                                                                            6430 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    149 
                                                                                                                                                                                                                RPL3 
                                                                                                            6122 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    150 
                                                                                                                                                                                                                LAMP2 
                                                                                                            3920 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    151 
                                                                                                                                                                                                                H1F0 
                                                                                                            3005 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    152 
                                                                                                                                                                                                            SUZ12 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    153 
                                                                                                                                                                                                                NXF1 
                                                                                                            10482 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                        Affinity Capture-RNA 
                                                                                                                                        Homo sapiens 
                                                                                                                                                                                                                                                             
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    154 
                                                                                                                                                                                                                RPS10 
                                                                                                            6204 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    155 
                                                                                                                                                                                                            SOX15 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    156 
                                                                                                                                                                                                                TPBG 
                                                                                                            7162 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    157 
                                                                                                                                                                                                                HIST1H2AB 
                                                                                                            8335 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    158 
                                                                                                                                                                                                                CEP250 
                                                                                                            11190 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    159 
                                                                                                                                                                                                                NUP43 
                                                                                                            348995 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Proximity Label-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    160 
                                                                                                                                                                                                                RPL36 
                                                                                                            25873 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    161 
                                                                                                                                                                                                            BRDT 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    162 
                                                                                                                                                                                                            MYC 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    163 
                                                                                                                                                                                                                RPA3 
                                                                                                            6119 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Proximity Label-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    164 
                                                                                                                                                                                                            ZC3H18 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    165 
                                                                                                                                                                                                                DNAJC9 
                                                                                                            23234 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Proximity Label-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    166 
                                                                                                                                                                                                                DLST 
                                                                                                            1743 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    167 
                                                                                                                                                                                                                RPS14 
                                                                                                            6208 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    168 
                                                                                                                                                                                                                TOP1 
                                                                                                            7150 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    169 
                                                                                                                                                                                                                BRD4 
                                                                                                            23476 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    170 
                                                                                                                                                                                                                PTPRB 
                                                                                                            5787 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    171 
                                                                                                                                                                                                                SART3 
                                                                                                            9733 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                        Affinity Capture-MS 
                                                                                                                                        Homo sapiens 
                                                                                                                                                                                                                                                             
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    172 
                                                                                                                                                                                                                PPAN 
                                                                                                            56342 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    173 
                                                                                                                                                                                                                RPL18 
                                                                                                            6141 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    174 
                                                                                                                                                                                                                DDRGK1 
                                                                                                            65992 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    175 
                                                                                                                                                                                                            RNF2 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    176 
                                                                                                                                                                                                            BMI1 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    177 
                                                                                                                                                                                                                VDAC1 
                                                                                                            7416 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    178 
                                                                                                                                                                                                                NOP16 
                                                                                                            51491 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    179 
                                                                                                                                                                                                            CCDC140 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    180 
                                                                                                                                                                                                                Eif3e 
                                                                                                            16341 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Mus musculus 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    181 
                                                                                                                                                                                                                HIST1H1T 
                                                                                                            3010 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    182 
                                                                                                                                                                                                                RPL26 
                                                                                                            6154 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    183 
                                                                                                                                                                                                                BRD3 
                                                                                                            8019 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    184 
                                                                                                                                                                                                                FTSJ3 
                                                                                                            117246 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    185 
                                                                                                                                                                                                            PYHIN1 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    186 
                                                                                                                                                                                                                ILF3 
                                                                                                            3609 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    187 
                                                                                                                                                                                                                TRA2A 
                                                                                                            29896 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    188 
                                                                                                                                                                                                                RPS16 
                                                                                                            6217 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                        Affinity Capture-MS 
                                                                                                                                        Homo sapiens 
                                                                                                                                                                                                                                                             
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    189 
                                                                                                                                                                                                                IMMT 
                                                                                                            10989 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    190 
                                                                                                                                                                                                            MB21D1 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Proximity Label-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    191 
                                                                                                                                                                                                            TLX1 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    192 
                                                                                                                                                                                                                DEPDC1B 
                                                                                                            55789 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    193 
                                                                                                                                                                                                                PLEKHA4 
                                                                                                            57664 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    194 
                                                                                                                                                                                                                RBM19 
                                                                                                            9904 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    195 
                                                                                                                                                                                                                RPS3 
                                                                                                            6188 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    196 
                                                                                                                                                                                                                HDGF 
                                                                                                            3068 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    197 
                                                                                                                                                                                                                HIST1H2BK 
                                                                                                            85236 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Cross-Linking-MS (XL-MS) 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    198 
                                                                                                                                                                                                            FBXL6 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Proximity Label-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    199 
                                                                                                                                                                                                                TP53 
                                                                                                            7157 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    200 
                                                                                                                                                                                                                RRS1 
                                                                                                            23212 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    201 
                                                                                                                                                                                                                RUVBL2 
                                                                                                            10856 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    202 
                                                                                                                                                                                                                MNDA 
                                                                                                            4332 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    203 
                                                                                                                                                                                                                ATG13 
                                                                                                            9776 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    204 
                                                                                                                                                                                                                SON 
                                                                                                            6651 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    205 
                                                                                                                                                                                                                MEN1 
                                                                                                            4221 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    206 
                                                                                                                                                                                                            ZCRB1 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    207 
                                                                                                                                                                                                                CUL5 
                                                                                                            8065 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    208 
                                                                                                                                                                                                                PDHA1 
                                                                                                            5160 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    209 
                                                                                                                                                                                                                HMGN5 
                                                                                                            79366 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    210 
                                                                                                                                                                                                                SMURF1 
                                                                                                            57154 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    211 
                                                                                                                                                                                                            ZNF48 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    212 
                                                                                                                                                                                                            UTP23 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    213 
                                                                                                                                                                                                                HSP90AA1 
                                                                                                            3320 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-Luminescence 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    214 
                                                                                                                                                                                                                SHMT2 
                                                                                                            6472 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-RNA 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    215 
                                                                                                                                                                                                            PRR3 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    216 
                                                                                                                                                                                                                ARF4 
                                                                                                            378 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Proximity Label-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    217 
                                                                                                                                                                                                                VTN 
                                                                                                            7448 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    218 
                                                                                                                                                                                                                TOP2A 
                                                                                                            7153 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    219 
                                                                                                                                                                                                            ESR1 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    220 
                                                                                                                                                                                                                UFL1 
                                                                                                            23376 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    221 
                                                                                                                                                                                                                KRR1 
                                                                                                            11103 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    222 
                                                                                                                                                                                                                RBM4 
                                                                                                            5936 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    223 
                                                                                                                                                                                                            NEIL1 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    224 
                                                                                                                                                                                                                RIOK2 
                                                                                                            55781 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    225 
                                                                                                                                                                                                            GLI4 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    226 
                                                                                                                                                                                                                RPS8 
                                                                                                            6202 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                        Affinity Capture-MS 
                                                                                                                                        Homo sapiens 
                                                                                                                                                                                                                                                             
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    227 
                                                                                                                                                                                                                CUL7 
                                                                                                            9820 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    228 
                                                                                                                                                                                                                ARHGAP23 
                                                                                                            57636 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    229 
                                                                                                                                                                                                                NRD1 
                                                                                                            4898 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    230 
                                                                                                                                                                                                                NUCKS1 
                                                                                                            64710 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    231 
                                                                                                                                                                                                                ARHGEF10L 
                                                                                                            55160 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    232 
                                                                                                                                                                                                                H1FOO 
                                                                                                            132243 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    233 
                                                                                                                                                                                                                RPL17 
                                                                                                            6139 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                                                                                                                
                                                                                                    
                                                                                                        View the network 
                                                                                                     
                                                                                                    
                                                                                                        
                                                                                                                    
                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                            image/svg+xml 
                                                                                                                             
                                                                                                                         
                                                                                                                         
                                                                                                                         
                                                                                                         
                                                                                                     
                                                                                                 
                                                                                                                                                                            
                                                                                 
                                                                             
                                                            
                                                         
                                                        
                                                        
                                                        
                                                            
                                                                
                                                                    
                                                                        HP1BP3  is involved
                                                                            
                                                                                                                                                                            No pathways found