Gene description for PARP10
Gene name	poly (ADP-ribose) polymerase family, member 10
Gene symbol	PARP10
Other names/aliases	ARTD10
Species	Homo sapiens
Database cross references - PARP10
ExoCarta	ExoCarta_84875
Vesiclepedia	VP_84875
Entrez Gene	84875
HGNC	25895
MIM	609564
UniProt	Q53GL7
PARP10 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable
Thymus	23844026

Gene ontology annotations for PARP10

Molecular Function     transcription corepressor activity GO:0003714 IBA     NAD+-protein poly-ADP-ribosyltransferase activity GO:0003950 IBA     NAD+-protein poly-ADP-ribosyltransferase activity GO:0003950 IMP     NAD+-protein poly-ADP-ribosyltransferase activity GO:0003950 TAS     protein binding GO:0005515 IPI     nucleotidyltransferase activity GO:0016779 IEA     K63-linked polyubiquitin modification-dependent protein binding GO:0070530 IMP     DNA-binding transcription factor binding GO:0140297 IPI     NAD+-protein-lysine ADP-ribosyltransferase activity GO:0140804 IEA     NAD+-protein-aspartate ADP-ribosyltransferase activity GO:0140806 IEA     NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity GO:0140822 IEA     NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity GO:0140844 IEA     NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity GO:0140867 IEA     NAD+-protein ADP-ribosyltransferase activity GO:1990404 IBA     NAD+-protein ADP-ribosyltransferase activity GO:1990404 IDA     NAD+-protein ADP-ribosyltransferase activity GO:1990404 IMP Biological Process     chromatin organization GO:0006325 IDA     negative regulation of gene expression GO:0010629 IBA     negative regulation of gene expression GO:0010629 IMP     viral protein processing GO:0019082 TAS     translesion synthesis GO:0019985 IDA     negative regulation of NF-kappaB transcription factor activity GO:0032088 IMP     NAD biosynthesis via nicotinamide riboside salvage pathway GO:0034356 TAS     negative regulation of DNA-templated transcription GO:0045892 IEA     negative regulation of fibroblast proliferation GO:0048147 IDA     protein poly-ADP-ribosylation GO:0070212 IDA     protein poly-ADP-ribosylation GO:0070212 IMP     protein auto-ADP-ribosylation GO:0070213 IDA     protein auto-ADP-ribosylation GO:0070213 IMP     negative regulation of protein K63-linked ubiquitination GO:1900045 IMP Subcellular Localization     nucleus GO:0005634 IBA     nucleus GO:0005634 IDA     nucleolus GO:0005730 IDA     cytoplasm GO:0005737 IBA     cytoplasm GO:0005737 IDA     Golgi apparatus GO:0005794 IDA     cytosol GO:0005829 IDA     cytosol GO:0005829 TAS