Gene description for TSSK6
Gene name testis-specific serine kinase 6
Gene symbol TSSK6
Other names/aliases CT72
FKSG82
SSTK
TSSK4
Species Homo sapiens
 Database cross references - TSSK6
ExoCarta ExoCarta_83983
Entrez Gene 83983
HGNC 30410
MIM 610712
UniProt Q9BXA6  
 TSSK6 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
 Gene ontology annotations for TSSK6
Molecular Function
    ATP binding GO:0005524 IDA
    magnesium ion binding GO:0000287 IDA
    protein binding GO:0005515 IPI
    protein serine/threonine kinase activity GO:0004674 IDA
Biological Process
    multicellular organismal development GO:0007275 IEA
    protein phosphorylation GO:0006468 IDA
    intracellular signal transduction GO:0035556 IBA
    sperm chromatin condensation GO:0035092 ISS
    regulation of signal transduction GO:0009966 IEA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified TSSK6 in exosomes
1
Experiment ID 235
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
2
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for TSSK6
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which TSSK6 is involved
No pathways found





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