Gene description for POLR2A
Gene name polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
Gene symbol POLR2A
Other names/aliases POLR2
POLRA
RPB1
RPBh1
RPO2
RPOL2
RpIILS
hRPB220
hsRPB1
Species Homo sapiens
 Database cross references - POLR2A
ExoCarta ExoCarta_5430
Vesiclepedia VP_5430
Entrez Gene 5430
HGNC 9187
MIM 180660
UniProt P24928  
 POLR2A identified in sEVs derived from the following tissue/cell type
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Embryonic kidney cells 36706192    
Embryonic kidney cells 36706192    
Endothelial cells 26027894    
Mesenchymal stem cells 36408942    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Thymus 23844026    
 Gene ontology annotations for POLR2A
Molecular Function
    magnesium ion binding GO:0000287 IDA
    RNA polymerase I activity GO:0001054 IEA
    RNA polymerase II activity GO:0001055 IBA
    RNA polymerase II activity GO:0001055 TAS
    RNA polymerase III activity GO:0001056 IEA
    RNA polymerase IV activity GO:0001057 IEA
    RNA polymerase V activity GO:0001058 IEA
    mitochondrial single subunit type RNA polymerase activity GO:0001065 IEA
    plastid single subunit type RNA polymerase activity GO:0001066 IEA
    DNA binding GO:0003677 NAS
    RNA binding GO:0003723 HDA
    DNA-directed 5'-3' RNA polymerase activity GO:0003899 IDA
    DNA-directed 5'-3' RNA polymerase activity GO:0003899 NAS
    RNA-dependent RNA polymerase activity GO:0003968 IDA
    protein binding GO:0005515 IPI
    protein binding GO:0005515 IPI
    zinc ion binding GO:0008270 IDA
    hydrolase activity GO:0016787 IEA
    kinase binding GO:0019900 IPI
    ubiquitin protein ligase binding GO:0031625 IPI
    microfibril binding GO:0050436 EXP
    microfibril binding GO:0050436 IDA
    promoter-specific chromatin binding GO:1990841 IDA
Biological Process
    transcription by RNA polymerase IV GO:0001059 IEA
    transcription by RNA polymerase V GO:0001060 IEA
    RNA-templated transcription GO:0001172 IEA
    DNA-templated transcription termination GO:0006353 IMP
    regulation of DNA-templated transcription GO:0006355 NAS
    transcription by RNA polymerase I GO:0006360 IEA
    transcription by RNA polymerase II GO:0006366 IDA
    transcription by RNA polymerase II GO:0006366 NAS
    transcription by RNA polymerase II GO:0006366 TAS
    transcription by RNA polymerase III GO:0006383 IEA
    mitochondrial transcription GO:0006390 IEA
    positive regulation of RNA splicing GO:0033120 IDA
    plastid transcription GO:0042793 IEA
Subcellular Localization
    Prp19 complex GO:0000974 IDA
    nucleus GO:0005634 IDA
    nucleus GO:0005634 NAS
    nucleus GO:0005634 TAS
    nucleoplasm GO:0005654 TAS
    RNA polymerase II, core complex GO:0005665 IBA
    RNA polymerase II, core complex GO:0005665 IDA
    chromosome GO:0005694 IEA
    nucleolus GO:0005730 IDA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified POLR2A in sEVs
1
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
4
Experiment ID 1275
MISEV standards
Biophysical techniques
✔
CD9|TSG101|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
5
Experiment ID 1280
MISEV standards
Biophysical techniques
✔
TSG101|CD9|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T - Fraction 5
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density 1.151 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 226
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD9|FLOT1
Enriched markers
✔
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
✘ Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
7
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for POLR2A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HIST2H2BE 8349
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
2 PQBP1  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
3 TXNIP 10628
Affinity Capture-MS Homo sapiens
4 MED17  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 Ruvbl1 56505
Affinity Capture-MS Mus musculus
6 USPL1  
Co-localization Homo sapiens
7 MED29  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 HIST1H2BH 8345
Cross-Linking-MS (XL-MS) Homo sapiens
9 MED13L 23389
Affinity Capture-MS Homo sapiens
10 MAP4 4134
Co-fractionation Homo sapiens
11 SETX  
Affinity Capture-Western Homo sapiens
12 CSNK2A1 1457
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
13 VHL  
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
14 SCAF4 57466
Affinity Capture-MS Homo sapiens
15 INTS1 26173
Affinity Capture-MS Homo sapiens
16 AKAP8L  
Co-fractionation Homo sapiens
17 TCEB3 6924
Co-localization Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-localization Homo sapiens
18 LMO2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 CCNK  
Affinity Capture-Western Homo sapiens
20 CPSF2 53981
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
21 MED13 9969
Affinity Capture-MS Homo sapiens
22 WDR76  
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
23 GTF2E2  
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
24 SMYD3 64754
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
25 SRC 6714
Co-localization Homo sapiens
Co-localization Homo sapiens
26 CRCP  
Affinity Capture-MS Homo sapiens
27 PSMB9 5698
Co-localization Homo sapiens
Co-localization Homo sapiens
28 POLR2C 5432
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
29 MECP2 4204
Affinity Capture-MS Homo sapiens
30 GPS1 2873
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
31 MTA2 9219
Co-fractionation Homo sapiens
32 UNK  
Affinity Capture-RNA Homo sapiens
33 TAZ  
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
34 ATF7IP 55729
Affinity Capture-Western Homo sapiens
35 MED7  
Affinity Capture-MS Homo sapiens
36 DPYSL3 1809
Affinity Capture-MS Homo sapiens
37 PDRG1  
Affinity Capture-MS Homo sapiens
38 SUPT5H 6829
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
39 CSTF2 1478
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
40 MNAT1  
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
41 YAP1 10413
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
42 SLX4  
Co-localization Homo sapiens
43 HIST1H1C 3006
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
44 MED25  
Affinity Capture-MS Homo sapiens
45 CUL2 8453
Affinity Capture-MS Homo sapiens
46 SND1 27044
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
47 BRCA1 672
Affinity Capture-Western Homo sapiens
Co-purification Homo sapiens
Affinity Capture-Western Homo sapiens
Co-purification Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
48 CD3EAP  
Affinity Capture-MS Homo sapiens
49 ZNF326 284695
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
50 DDX5 1655
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
51 PHLPP1  
Proximity Label-MS Homo sapiens
52 SMYD5 10322
Co-localization Homo sapiens
53 HIST1H2BL 8340
Cross-Linking-MS (XL-MS) Homo sapiens
54 GTF3C3 9330
Co-fractionation Homo sapiens
55 CSTF1 1477
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
56 ARRDC4  
Affinity Capture-MS Homo sapiens
57 SIRT7  
Affinity Capture-MS Homo sapiens
58 EPAS1  
Affinity Capture-MS Homo sapiens
59 CUL3 8452
Affinity Capture-MS Homo sapiens
60 Cstf1  
Reconstituted Complex Rattus norvegicus
61 POLR2D  
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
62 EGLN1 54583
Affinity Capture-Western Homo sapiens
63 TBP  
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
64 PRMT5 10419
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
65 CCNL2 81669
Affinity Capture-Western Homo sapiens
66 RPA3 6119
Proximity Label-MS Homo sapiens
67 Nedd4 17999
Affinity Capture-Western Mus musculus
68 C7orf60 154743
Affinity Capture-MS Homo sapiens
69 INTS5 80789
Affinity Capture-MS Homo sapiens
70 SUPT16H 11198
Co-fractionation Homo sapiens
71 MED14  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 PKHD1L1 93035
Affinity Capture-MS Homo sapiens
73 RELA 5970
Co-localization Homo sapiens
74 NUDT21 11051
Co-fractionation Homo sapiens
75 GRB2 2885
Two-hybrid Homo sapiens
76 POLR2J  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
77 CDK8 1024
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
78 WWOX 51741
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
79 TCERG1 10915
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Far Western Homo sapiens
80 WDR92 116143
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 POLR3H  
Affinity Capture-MS Homo sapiens
82 HIST1H2BC 8347
Cross-Linking-MS (XL-MS) Homo sapiens
83 DCTN2 10540
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
84 RUVBL2 10856
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
85 TTK 7272
Biochemical Activity Homo sapiens
86 SUPT4H1  
Co-fractionation Homo sapiens
87 C11orf74  
Two-hybrid Homo sapiens
88 GTF2B 2959
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
89 ERCC3  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
90 WWP2 11060
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
91 ERCC6  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
92 NCL 4691
Co-fractionation Homo sapiens
93 BCL2  
Co-localization Homo sapiens
94 PSMA5 5686
Co-fractionation Homo sapiens
95 SUPT6H 6830
Affinity Capture-Western Homo sapiens
Far Western Homo sapiens
Co-fractionation Homo sapiens
96 POLR3B 55703
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
97 CEBPB  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
98 INTS3 65123
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
99 PTGES3 10728
Affinity Capture-MS Homo sapiens
100 CUL7 9820
Affinity Capture-MS Homo sapiens
101 POLR1D 51082
Affinity Capture-MS Homo sapiens
102 UBN1  
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
103 PHF8  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
104 PSMA6 5687
Co-fractionation Homo sapiens
105 MCM3 4172
Affinity Capture-Western Homo sapiens
106 SMC3 9126
Affinity Capture-Western Homo sapiens
107 QKI 9444
Affinity Capture-MS Homo sapiens
108 XPA  
Affinity Capture-Western Homo sapiens
109 RECQL5  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Far Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
110 ATM 472
Co-localization Homo sapiens
Biochemical Activity Homo sapiens
111 CAND1 55832
Affinity Capture-MS Homo sapiens
112 SRSF2 6427
Co-fractionation Homo sapiens
113 SNRPF 6636
Affinity Capture-MS Homo sapiens
114 URI1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
115 Med22  
Affinity Capture-MS Mus musculus
116 ZNF74  
Affinity Capture-Western Homo sapiens
Far Western Homo sapiens
117 COPS6 10980
Co-fractionation Homo sapiens
118 PHLDA2 7262
Cross-Linking-MS (XL-MS) Homo sapiens
119 PRC1 9055
Affinity Capture-MS Homo sapiens
120 COPS2 9318
Co-fractionation Homo sapiens
121 MED27  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
122 OBSL1 23363
Affinity Capture-MS Homo sapiens
123 KMT2D 8085
Reconstituted Complex Homo sapiens
124 CDK7 1022
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
125 Clp1  
Affinity Capture-MS Mus musculus
126 LEO1 123169
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
127 HAP1  
Affinity Capture-Western Homo sapiens
128 NSD1  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
129 Eif3a 13669
Affinity Capture-MS Mus musculus
130 POLR2M  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
131 SETD1A 9739
Affinity Capture-Western Homo sapiens
132 ASF1A 25842
Co-localization Homo sapiens
133 GPR156  
Affinity Capture-MS Homo sapiens
134 MED4 29079
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
135 GPN3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
136 GTF2I 2969
Affinity Capture-Western Homo sapiens
137 Supt6  
Affinity Capture-Western Mus musculus
Reconstituted Complex Mus musculus
Far Western Mus musculus
Far Western Mus musculus
138 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
139 CABIN1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
140 RBX1 9978
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
141 CTDP1 9150
Co-purification Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
142 CDKN1A  
Affinity Capture-RNA Homo sapiens
143 Pfdn2  
Affinity Capture-MS Mus musculus
144 TAF11  
Affinity Capture-Western Homo sapiens
Co-purification Homo sapiens
Reconstituted Complex Homo sapiens
145 IWS1  
Reconstituted Complex Homo sapiens
146 NELFE 7936
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-localization Homo sapiens
147 CSTF3 1479
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
148 ARRDC2  
Affinity Capture-MS Homo sapiens
149 MED26  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
150 COLQ  
Affinity Capture-MS Homo sapiens
151 PPP2CA 5515
Affinity Capture-MS Homo sapiens
152 EHBP1L1 254102
Co-fractionation Homo sapiens
153 CTR9 9646
Affinity Capture-MS Homo sapiens
154 COPS8 10920
Co-fractionation Homo sapiens
155 CDC14A  
Biochemical Activity Homo sapiens
156 HNRNPD 3184
Affinity Capture-MS Homo sapiens
157 COPS7A 50813
Co-fractionation Homo sapiens
158 SNAR-B2  
Reconstituted Complex Homo sapiens
159 CCNC  
Affinity Capture-MS Homo sapiens
160 XPO1 7514
Affinity Capture-MS Homo sapiens
161 UBE2L3 7332
Reconstituted Complex Homo sapiens
162 POLR2E 5434
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
163 RAD52  
Affinity Capture-Western Homo sapiens
164 ELP3 55140
Co-purification Homo sapiens
165 SETD2  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
166 ERCC4  
Affinity Capture-Western Homo sapiens
167 EGFR 1956
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
168 FUS 2521
Affinity Capture-MS Homo sapiens
169 CDK2 1017
Co-fractionation Homo sapiens
170 TADA2A  
Affinity Capture-MS Homo sapiens
171 MYC  
Affinity Capture-MS Homo sapiens
172 ZNRD1  
Affinity Capture-MS Homo sapiens
173 EEF1A2 1917
Co-fractionation Homo sapiens
174 DDB1 1642
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
175 Yap1  
Affinity Capture-Western Mus musculus
176 NELFB 25920
Affinity Capture-Western Homo sapiens
177 TAF4 6874
Affinity Capture-Western Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
178 HUWE1 10075
Affinity Capture-MS Homo sapiens
179 EEF1A1 1915
Co-fractionation Homo sapiens
180 MED11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
181 Ruvbl2 20174
Affinity Capture-MS Mus musculus
182 POLR2F  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
183 PARP1 142
Co-fractionation Homo sapiens
184 ILF3 3609
Co-fractionation Homo sapiens
185 COPS4 51138
Co-fractionation Homo sapiens
186 VWA9  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
187 MED6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
188 NELFA  
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
189 SETD1B 23067
Affinity Capture-Western Homo sapiens
190 ESR1  
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
191 MED21  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-purification Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
192 EGLN2  
Affinity Capture-Western Homo sapiens
193 EEF1D 1936
Cross-Linking-MS (XL-MS) Homo sapiens
194 POLR3D  
Affinity Capture-MS Homo sapiens
195 BRD1 23774
Affinity Capture-MS Homo sapiens
196 KRAS 3845
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
197 CCT8L2  
Affinity Capture-MS Homo sapiens
198 CPSF3 51692
Reconstituted Complex Homo sapiens
199 CUL4A 8451
Co-fractionation Homo sapiens
200 MED28  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
201 ATP6V1B2 526
Co-fractionation Homo sapiens
202 MCM7 4176
Affinity Capture-Western Homo sapiens
203 GTF2F1 2962
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
204 RNGTT 8732
Affinity Capture-MS Homo sapiens
205 ERCC2 2068
Affinity Capture-Western Homo sapiens
206 Gtf2b  
Affinity Capture-MS Mus musculus
207 HIST1H2BJ 8970
Cross-Linking-MS (XL-MS) Homo sapiens
208 ARMC5 79798
Affinity Capture-MS Homo sapiens
209 C7orf76  
Affinity Capture-MS Homo sapiens
210 XRN2 22803
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
211 HNRNPR 10236
Co-fractionation Homo sapiens
212 ERCC5  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
213 CTDSP2 10106
Biochemical Activity Homo sapiens
214 TRIM28 10155
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
215 LGR4 55366
Affinity Capture-MS Homo sapiens
216 MDC1  
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
217 POLR1E  
Affinity Capture-MS Homo sapiens
218 EWSR1 2130
Affinity Capture-Western Homo sapiens
219 BRINP1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
220 CRMP1 1400
Affinity Capture-MS Homo sapiens
221 ATG16L1 55054
Affinity Capture-MS Homo sapiens
222 GPN1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
223 VDR  
Co-localization Homo sapiens
Co-localization Homo sapiens
224 CSNK2B 1460
Affinity Capture-MS Homo sapiens
225 SMARCA2 6595
Co-purification Homo sapiens
Co-purification Homo sapiens
Co-localization Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
226 HSPA8 3312
Co-fractionation Homo sapiens
227 POLR2K  
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
228 MED1 5469
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
229 SCAF1  
Affinity Capture-MS Homo sapiens
230 TAF10 6881
Affinity Capture-Western Homo sapiens
231 PNKP 11284
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
232 SMEK1 55671
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
233 DNMT3A 1788
Affinity Capture-MS Homo sapiens
234 SRRT 51593
Co-fractionation Homo sapiens
235 CBX3 11335
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
236 GTF2H1 2965
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
237 BARD1 580
Affinity Capture-MS Homo sapiens
238 NTRK1 4914
Affinity Capture-MS Homo sapiens
239 U2AF2 11338
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
240 ZNF131  
Affinity Capture-MS Homo sapiens
241 ACTB 60
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
242 COPS3 8533
Co-fractionation Homo sapiens
243 FBLN5 10516
Affinity Capture-MS Homo sapiens
244 HIST1H2BK 85236
Cross-Linking-MS (XL-MS) Homo sapiens
245 MED31  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
246 DRAP1 10589
Co-fractionation Homo sapiens
247 POLR2B 5431
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
248 KMT2A  
Affinity Capture-Western Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
249 CDC73  
Affinity Capture-Western Homo sapiens
250 POLR3A 11128
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
251 BAZ1B 9031
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
252 DDX3Y 8653
Affinity Capture-MS Homo sapiens
253 HTATSF1 27336
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
254 NFKBIA  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
255 LIG3 3980
Affinity Capture-Western Homo sapiens
256 ZC3H4 23211
Protein-peptide Homo sapiens
257 OBFC1 79991
Affinity Capture-MS Homo sapiens
258 ERCC1  
Affinity Capture-Western Homo sapiens
259 POLR2A 5430
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
260 XAB2 56949
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
261 POLR3E 55718
Affinity Capture-MS Homo sapiens
262 SYDE1 85360
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
263 MED10  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
264 DNMT3B  
Affinity Capture-MS Homo sapiens
265 PRPF19 27339
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
266 PSPC1 55269
Cross-Linking-MS (XL-MS) Homo sapiens
267 RXRA 6256
Co-localization Homo sapiens
268 TOP1 7150
Affinity Capture-MS Homo sapiens
269 NHP2L1 4809
Affinity Capture-MS Homo sapiens
270 CPSF3L 54973
Affinity Capture-Western Homo sapiens
271 XRCC5 7520
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
272 CSH2  
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
273 DHX9 1660
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
274 MED19  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
275 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
276 SMN1 6606
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
277 SLC25A6 293
Cross-Linking-MS (XL-MS) Homo sapiens
278 CTDSP1 58190
Biochemical Activity Homo sapiens
279 Ep300  
Affinity Capture-Western Mus musculus
280 POLR1B 84172
Affinity Capture-MS Homo sapiens
281 AGO1  
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
282 PIN1 5300
Affinity Capture-Western Homo sapiens
283 KAT2B  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
284 RPA1 6117
Affinity Capture-Western Homo sapiens
285 MEN1 4221
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
286 SNRPA 6626
Affinity Capture-MS Homo sapiens
287 CREBBP  
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
288 DDX58 23586
Affinity Capture-RNA Homo sapiens
289 PCNA 5111
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
290 NF1 4763
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
291 MED18  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
292 RPL38 6169
Co-fractionation Homo sapiens
293 MED12  
Affinity Capture-MS Homo sapiens
294 Rprd1b  
Affinity Capture-MS Mus musculus
295 POLR1C 9533
Affinity Capture-MS Homo sapiens
296 CIT 11113
Affinity Capture-MS Homo sapiens
297 RPRD1B 58490
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
298 ERG  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
299 ZC3H13 23091
Affinity Capture-MS Homo sapiens
300 ATXN3 4287
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
301 CCNT1  
Biochemical Activity Homo sapiens
302 SSRP1 6749
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
303 TIMM44 10469
Cross-Linking-MS (XL-MS) Homo sapiens
304 EP300 2033
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
305 UBE2H 7328
Affinity Capture-MS Homo sapiens
306 POLR2G 5436
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
307 OTUD5 55593
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
308 CCNH  
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Co-fractionation Homo sapiens
309 WWP1 11059
Affinity Capture-MS Homo sapiens
310 FREM2 341640
Affinity Capture-MS Homo sapiens
311 RPAP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
312 ZNHIT2 741
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
313 SUB1 10923
Reconstituted Complex Homo sapiens
314 INTS10  
Affinity Capture-MS Homo sapiens
315 MED9  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
316 TDRD3  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
317 FAM168A  
Affinity Capture-MS Homo sapiens
318 AFF1  
Affinity Capture-MS Homo sapiens
319 TCEA1 6917
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
320 EIF4ENIF1 56478
Two-hybrid Homo sapiens
321 RPS20 6224
Co-fractionation Homo sapiens
322 GTF2F2 2963
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-purification Homo sapiens
Co-fractionation Homo sapiens
323 TGFB1 7040
Affinity Capture-MS Homo sapiens
324 POLR2I 5438
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
325 COPS5 10987
Co-fractionation Homo sapiens
326 FBXW7  
Affinity Capture-MS Homo sapiens
327 SNRPC 6631
Affinity Capture-MS Homo sapiens
328 HMGA1 3159
Affinity Capture-MS Homo sapiens
329 MED22  
Affinity Capture-MS Homo sapiens
330 BRD4 23476
Affinity Capture-MS Homo sapiens
331 INTS6 26512
Affinity Capture-MS Homo sapiens
332 MLLT1 4298
Affinity Capture-Western Homo sapiens
333 SMARCB1 6598
Co-purification Homo sapiens
Co-purification Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
334 NEDD4 4734
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
335 CTCF  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Co-purification Homo sapiens
Affinity Capture-Western Homo sapiens
336 POLR1A 25885
Affinity Capture-MS Homo sapiens
337 SRP9 6726
Affinity Capture-MS Homo sapiens
338 CPNE2 221184
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
339 MED20 9477
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
340 UXT 8409
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
341 ARRDC1 92714
Affinity Capture-MS Homo sapiens
342 NR0B2  
Reconstituted Complex Homo sapiens
343 HTT 3064
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
344 BRCA2 675
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
345 SMARCA4 6597
Co-purification Homo sapiens
Co-purification Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
346 PFDN2 5202
Affinity Capture-MS Homo sapiens
347 VCP 7415
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
348 HMGN1  
Affinity Capture-Western Homo sapiens
349 ARRDC3 57561
Affinity Capture-MS Homo sapiens
350 SMC1A 8243
Affinity Capture-Western Homo sapiens
351 EED  
Affinity Capture-MS Homo sapiens
352 ITCH 83737
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
353 RTEL1 51750
Co-localization Homo sapiens
354 SMARCC2 6601
Co-fractionation Homo sapiens
355 PPP4R1 9989
Co-fractionation Homo sapiens
356 NEURL4  
Affinity Capture-MS Homo sapiens
357 WDR82 80335
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
358 RPRD2  
Affinity Capture-MS Homo sapiens
359 CPSF1 29894
Reconstituted Complex Homo sapiens
360 TAF15 8148
Affinity Capture-Western Homo sapiens
361 HIST1H3A 8350
Cross-Linking-MS (XL-MS) Homo sapiens
362 FANCD2  
Affinity Capture-MS Homo sapiens
Co-localization Homo sapiens
363 POLR2H 5437
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
364 SNRPB 6628
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
365 CTNNB1 1499
Affinity Capture-MS Homo sapiens
366 ASB6 140459
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
367 CDK19 23097
Affinity Capture-MS Homo sapiens
368 ERCC8  
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
369 PCIF1 63935
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
370 RPRD1A  
Affinity Capture-MS Homo sapiens
371 NXF1 10482
Affinity Capture-RNA Homo sapiens
372 MAPK6  
Affinity Capture-MS Homo sapiens
373 DCUN1D1 54165
Affinity Capture-MS Homo sapiens
374 MYO6 4646
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
375 INO80B 83444
Affinity Capture-MS Homo sapiens
376 EEFSEC 60678
Co-fractionation Homo sapiens
377 RPAP3 79657
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
378 NFKB1 4790
Co-localization Homo sapiens
379 CCND1 595
Co-localization Homo sapiens
380 WAC  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Reconstituted Complex Homo sapiens
381 IRF3 3661
Co-localization Homo sapiens
382 CCDC8  
Affinity Capture-MS Homo sapiens
383 H2AFX 3014
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
384 RALBP1 10928
Co-fractionation Homo sapiens
385 UBE3B 89910
Co-fractionation Homo sapiens
386 NABP1  
Affinity Capture-MS Homo sapiens
387 SIRT6  
Affinity Capture-MS Homo sapiens
388 CPSF6 11052
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
389 SSU72 29101
Biochemical Activity Homo sapiens
Protein-peptide Homo sapiens
Co-crystal Structure Homo sapiens
390 POLR2L 5441
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
391 UVSSA  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
392 PHRF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
393 SMARCC1 6599
Co-fractionation Homo sapiens
394 CUL5 8065
Affinity Capture-MS Homo sapiens
395 HMGN5 79366
Affinity Capture-MS Homo sapiens
396 MED8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
397 SMURF1 57154
Biochemical Activity Homo sapiens
398 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
399 HIST1H2BD 3017
Cross-Linking-MS (XL-MS) Homo sapiens
400 BRCA1  
Affinity Capture-Western Bos taurus
401 CREB1  
Affinity Capture-MS Homo sapiens
402 MED30  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
403 MOV10 4343
Affinity Capture-RNA Homo sapiens
404 EZH2  
Affinity Capture-Western Homo sapiens
405 TRIP4 9325
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
406 AIRE  
Affinity Capture-MS Homo sapiens
407 CDK9 1025
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Co-fractionation Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
408 GTF2E1 2960
Reconstituted Complex Homo sapiens
Co-purification Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
409 PIH1D1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
410 HIRA  
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
411 GTF2H4 2968
Co-purification Homo sapiens
Reconstituted Complex Homo sapiens
412 HNRNPU 3192
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
413 C9orf72  
Affinity Capture-MS Homo sapiens
414 KBTBD4  
Affinity Capture-MS Homo sapiens
415 PAF1 54623
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
416 IVNS1ABP  
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
417 WDHD1  
Co-fractionation Homo sapiens
418 CDC5L 988
Co-fractionation Homo sapiens
View the network image/svg+xml
 Pathways in which POLR2A is involved
PathwayEvidenceSource
Abortive elongation of HIV-1 transcript in the absence of Tat IEA Reactome
Activation of anterior HOX genes in hindbrain development during early embryogenesis IEA Reactome
Activation of HOX genes during differentiation IEA Reactome
Cell Cycle TAS Reactome
Chromosome Maintenance TAS Reactome
Developmental Biology IEA Reactome
Disease IEA Reactome
Disease TAS Reactome
Diseases of signal transduction by growth factor receptors and second messengers IEA Reactome
DNA Repair TAS Reactome
Dual incision in TC-NER TAS Reactome
ESR-mediated signaling TAS Reactome
Estrogen-dependent gene expression TAS Reactome
FGFR2 alternative splicing TAS Reactome
FGFR2 mutant receptor activation IEA Reactome
Formation of HIV elongation complex in the absence of HIV Tat IEA Reactome
Formation of HIV-1 elongation complex containing HIV-1 Tat TAS Reactome
Formation of HIV-1 elongation complex containing HIV-1 Tat IEA Reactome
Formation of RNA Pol II elongation complex TAS Reactome
Formation of TC-NER Pre-Incision Complex TAS Reactome
Formation of the Early Elongation Complex TAS Reactome
Formation of the HIV-1 Early Elongation Complex IEA Reactome
Gap-filling DNA repair synthesis and ligation in TC-NER TAS Reactome
Gene expression (Transcription) IEA Reactome
Gene expression (Transcription) TAS Reactome
Gene Silencing by RNA IEA Reactome
Gene Silencing by RNA TAS Reactome
Generic Transcription Pathway TAS Reactome
HIV elongation arrest and recovery IEA Reactome
HIV Infection IEA Reactome
HIV Infection TAS Reactome
HIV Life Cycle IEA Reactome
HIV Life Cycle TAS Reactome
HIV Transcription Elongation TAS Reactome
HIV Transcription Elongation IEA Reactome
HIV Transcription Initiation IEA Reactome
Infectious disease IEA Reactome
Infectious disease TAS Reactome
Influenza Infection TAS Reactome
Influenza Viral RNA Transcription and Replication TAS Reactome
Inhibition of DNA recombination at telomere TAS Reactome
Late Phase of HIV Life Cycle IEA Reactome
Late Phase of HIV Life Cycle TAS Reactome
Metabolism of RNA TAS Reactome
MicroRNA (miRNA) biogenesis TAS Reactome
mRNA Capping TAS Reactome
mRNA Splicing TAS Reactome
mRNA Splicing - Major Pathway TAS Reactome
mRNA Splicing - Minor Pathway TAS Reactome
Nucleotide Excision Repair TAS Reactome
Pausing and recovery of HIV elongation IEA Reactome
Pausing and recovery of Tat-mediated HIV elongation IEA Reactome
PIWI-interacting RNA (piRNA) biogenesis IEA Reactome
Processing of Capped Intron-Containing Pre-mRNA TAS Reactome
RNA Pol II CTD phosphorylation and interaction with CE TAS Reactome
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection IEA Reactome
RNA Polymerase II HIV Promoter Escape IEA Reactome
RNA Polymerase II Pre-transcription Events TAS Reactome
RNA Polymerase II Promoter Escape TAS Reactome
RNA polymerase II transcribes snRNA genes TAS Reactome
RNA polymerase II transcribes snRNA genes IEA Reactome
RNA Polymerase II Transcription TAS Reactome
RNA Polymerase II Transcription IEA Reactome
RNA Polymerase II Transcription Elongation TAS Reactome
RNA Polymerase II Transcription Initiation TAS Reactome
RNA Polymerase II Transcription Initiation And Promoter Clearance TAS Reactome
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening TAS Reactome
Signal Transduction TAS Reactome
Signaling by FGFR TAS Reactome
Signaling by FGFR in disease IEA Reactome
Signaling by FGFR2 TAS Reactome
Signaling by FGFR2 IIIa TM IEA Reactome
Signaling by FGFR2 in disease IEA Reactome
Signaling by Nuclear Receptors TAS Reactome
Signaling by Receptor Tyrosine Kinases TAS Reactome
Tat-mediated elongation of the HIV-1 transcript TAS Reactome
Tat-mediated elongation of the HIV-1 transcript IEA Reactome
Tat-mediated HIV elongation arrest and recovery IEA Reactome
Telomere Maintenance TAS Reactome
TP53 Regulates Transcription of DNA Repair Genes TAS Reactome
Transcription of the HIV genome IEA Reactome
Transcription of the HIV genome TAS Reactome
Transcription-Coupled Nucleotide Excision Repair (TC-NER) TAS Reactome
Transcriptional regulation by small RNAs TAS Reactome
Transcriptional Regulation by TP53 TAS Reactome
Viral Infection Pathways IEA Reactome
Viral Infection Pathways TAS Reactome
Viral Messenger RNA Synthesis TAS Reactome





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