Gene description for RFC1
Gene name	replication factor C (activator 1) 1, 145kDa
Gene symbol	RFC1
Other names/aliases	A1 MHCBFB PO-GA RECC1 RFC RFC140
Species	Homo sapiens
Database cross references - RFC1
ExoCarta	ExoCarta_5981
Entrez Gene	5981
HGNC	9969
MIM	102579
UniProt	P35251
RFC1 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723
Urine	19056867

Gene ontology annotations for RFC1

Molecular Function     ATP binding GO:0005524 IEA     DNA binding GO:0003677 IBA     double-stranded DNA binding GO:0003690 IEA     protein binding GO:0005515 IPI     enzyme activator activity GO:0008047 TAS     sequence-specific DNA binding GO:0043565 IEA     DNA clamp loader activity GO:0003689 IEA     protein domain specific binding GO:0019904 IEA Biological Process     error-prone translesion synthesis GO:0042276 TAS     transcription, DNA-templated GO:0006351 IEA     telomere maintenance via recombination GO:0000722 TAS     DNA-dependent DNA replication GO:0006261 TAS     DNA repair GO:0006281 TAS     positive regulation of catalytic activity GO:0043085 TAS     telomere maintenance via semi-conservative replication GO:0032201 TAS     transcription-coupled nucleotide-excision repair GO:0006283 TAS     mitotic cell cycle GO:0000278 TAS     DNA damage response, detection of DNA damage GO:0042769 TAS     error-free translesion synthesis GO:0070987 TAS     positive regulation of transcription, DNA-templated GO:0045893 IEA     nucleotide-excision repair GO:0006289 TAS     DNA strand elongation involved in DNA replication GO:0006271 TAS     telomere maintenance via telomerase GO:0007004 TAS     translesion synthesis GO:0019985 TAS     nucleotide-excision repair, DNA gap filling GO:0006297 TAS     negative regulation of transcription from RNA polymerase II promoter GO:0000122 IEA     base-excision repair GO:0006284 TAS     telomere maintenance GO:0000723 TAS Subcellular Localization     DNA replication factor C complex GO:0005663 IDA     nucleolus GO:0005730 IEA     Golgi apparatus GO:0005794 IDA     nucleus GO:0005634 IDA     nucleoplasm GO:0005654 TAS     extracellular exosome GO:0070062 IDA     cell junction GO:0030054 IDA