Gene description for PRELP
Gene name proline/arginine-rich end leucine-rich repeat protein
Gene symbol PRELP
Other names/aliases MST161
Species Homo sapiens
 Database cross references - PRELP
ExoCarta ExoCarta_5549
Entrez Gene 5549
HGNC 9357
MIM 601914
UniProt P51888  
 PRELP identified in exosomes derived from the following tissue/cell type
Saliva 19199708    
 Gene ontology annotations for PRELP
Molecular Function
    heparin binding GO:0008201 IEA
    extracellular matrix structural constituent GO:0005201 IEA
Biological Process
    keratan sulfate catabolic process GO:0042340 TAS
    skeletal system development GO:0001501 TAS
    keratan sulfate biosynthetic process GO:0018146 TAS
    carbohydrate metabolic process GO:0005975 TAS
    keratan sulfate metabolic process GO:0042339 TAS
    small molecule metabolic process GO:0044281 TAS
    glycosaminoglycan metabolic process GO:0030203 TAS
    cell aging GO:0007569 IEA
Subcellular Localization
    lysosomal lumen GO:0043202 TAS
    extracellular region GO:0005576 TAS
    extracellular exosome GO:0070062 IDA
    extracellular vesicle GO:1903561 IDA
    extracellular matrix GO:0031012 ISS
    proteinaceous extracellular matrix GO:0005578 IEA
    Golgi lumen GO:0005796 TAS
 Experiment description of studies that identified PRELP in exosomes
Experiment ID 66
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for PRELP
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HSPG2 3339
Reconstituted Complex Homo sapiens
2 FBLN2 2199
Reconstituted Complex Homo sapiens
3 COL1A1 1277
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
4 COL2A1 1280
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
5 NID2 22795
Reconstituted Complex Homo sapiens
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