Gene description for PGRMC1
Gene name progesterone receptor membrane component 1
Gene symbol PGRMC1
Other names/aliases HPR6.6
MPR
Species Homo sapiens
 Database cross references - PGRMC1
ExoCarta ExoCarta_10857
Vesiclepedia VP_10857
Entrez Gene 10857
HGNC 16090
MIM 300435
UniProt O00264  
 PGRMC1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Cholangiocarcinoma cells 31054213    
Cholangiocarcinoma cells 31054213    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Mesenchymal stem cells 36408942    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Thymus 23844026    
 Gene ontology annotations for PGRMC1
Molecular Function
    amyloid-beta binding GO:0001540 TAS
    steroid binding GO:0005496 IEA
    protein binding GO:0005515 IPI
    heme binding GO:0020037 IDA
    heme binding GO:0020037 TAS
    protein homodimerization activity GO:0042803 IDA
    metal ion binding GO:0046872 IEA
Biological Process
    heme biosynthetic process GO:0006783 IDA
    positive regulation of lipoprotein transport GO:0140077 IMP
    positive regulation of protein localization to plasma membrane GO:1903078 IMP
Subcellular Localization
    extracellular region GO:0005576 IEA
    mitochondrial outer membrane GO:0005741 ISS
    endoplasmic reticulum GO:0005783 IBA
    endoplasmic reticulum GO:0005783 TAS
    plasma membrane GO:0005886 TAS
    plasma membrane GO:0005886 TAS
    endomembrane system GO:0012505 IBA
    membrane GO:0016020 HDA
    membrane GO:0016020 IBA
    smooth endoplasmic reticulum membrane GO:0030868 IEA
    specific granule membrane GO:0035579 TAS
    neuron projection GO:0043005 ISS
    neuronal cell body GO:0043025 ISS
    cell body GO:0044297 ISS
    synapse GO:0045202 ISS
 Experiment description of studies that identified PGRMC1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 1225
MISEV standards
✔
EM
Biophysical techniques
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 31054213    
Organism Homo sapiens
Experiment description Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma
Authors "Weeraphan C, Phongdara A, Chaiyawat P, Diskul-Na-Ayudthaya P, Chokchaichamnankit D, Verathamjamras C, Netsirisawan P, Yingchutrakul Y, Roytrakul S, Champattanachai V, Svasti J, Srisomsap C."
Journal name Proteomics
Publication year 2019
Sample Cholangiocarcinoma cells
Sample name KKU-M213 - in-solution digestion
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
6
Experiment ID 1226
MISEV standards
✔
EM
Biophysical techniques
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 31054213    
Organism Homo sapiens
Experiment description Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma
Authors "Weeraphan C, Phongdara A, Chaiyawat P, Diskul-Na-Ayudthaya P, Chokchaichamnankit D, Verathamjamras C, Netsirisawan P, Yingchutrakul Y, Roytrakul S, Champattanachai V, Svasti J, Srisomsap C."
Journal name Proteomics
Publication year 2019
Sample Cholangiocarcinoma cells
Sample name KKU-M213D5 - in-solution digestion
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
10
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PGRMC1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HNRNPH1 3187
Co-fractionation Homo sapiens
2 INSIG1  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
3 HACD3 51495
Affinity Capture-MS Homo sapiens
4 UBE2H 7328
Affinity Capture-MS Homo sapiens
5 HSD17B11 51170
Proximity Label-MS Homo sapiens
6 TMCO1 54499
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 POR 5447
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
8 UBL4A 8266
Affinity Capture-MS Homo sapiens
9 COIL  
Proximity Label-MS Homo sapiens
10 CYP1A2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 KRTCAP2 200185
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 MARCKS 4082
Proximity Label-MS Homo sapiens
13 LAMP3  
Proximity Label-MS Homo sapiens
14 RIN3  
Affinity Capture-MS Homo sapiens
15 SRPRB 58477
Affinity Capture-MS Homo sapiens
16 RPA2 6118
Affinity Capture-MS Homo sapiens
17 ADRB2  
Affinity Capture-MS Homo sapiens
18 BNIP1 662
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 PHOSPHO1  
Affinity Capture-MS Homo sapiens
20 GJD3  
Proximity Label-MS Homo sapiens
21 ZNF71  
Two-hybrid Homo sapiens
22 LAMP2 3920
Proximity Label-MS Homo sapiens
23 DNAJC25 548645
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
24 PTPN1 5770
Affinity Capture-MS Homo sapiens
25 DNAJB3 414061
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
26 GCN1L1 10985
Co-fractionation Homo sapiens
27 APOD 347
Affinity Capture-MS Homo sapiens
28 TMEM213  
Two-hybrid Homo sapiens
29 VAPA 9218
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 KIAA1429 25962
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 CENPU  
Two-hybrid Homo sapiens
32 RPS20 6224
Co-fractionation Homo sapiens
33 WDR76  
Affinity Capture-MS Homo sapiens
34 KLF8  
Affinity Capture-MS Homo sapiens
35 RINT1 60561
Affinity Capture-MS Homo sapiens
36 OSBP 5007
Affinity Capture-MS Homo sapiens
37 COPS5 10987
Affinity Capture-MS Homo sapiens
38 TMED2 10959
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 STT3A 3703
Affinity Capture-MS Homo sapiens
40 SLC6A3  
Affinity Capture-Western Homo sapiens
41 ABCD3 5825
Affinity Capture-MS Homo sapiens
42 DUSP21  
Affinity Capture-MS Homo sapiens
43 SSR1 6745
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 RER1 11079
Affinity Capture-MS Homo sapiens
45 DDOST 1650
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 DNAJB1 3337
Proximity Label-MS Homo sapiens
47 PGRMC2 10424
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
48 VAPB 9217
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 ARHGAP19  
Affinity Capture-MS Homo sapiens
50 ERMP1 79956
Affinity Capture-MS Homo sapiens
51 CCDC47 57003
Affinity Capture-MS Homo sapiens
52 BCAP29 55973
Affinity Capture-MS Homo sapiens
53 KCNE1L  
Two-hybrid Homo sapiens
54 SCD5  
Affinity Capture-MS Homo sapiens
55 BET1 10282
Affinity Capture-MS Homo sapiens
56 RAB3B 5865
Proximity Label-MS Homo sapiens
57 MECP2 4204
Affinity Capture-MS Homo sapiens
58 RAB35 11021
Proximity Label-MS Homo sapiens
59 LCLAT1 253558
Affinity Capture-MS Homo sapiens
60 GPX8 493869
Affinity Capture-MS Homo sapiens
61 SSR3 6747
Affinity Capture-MS Homo sapiens
62 FGFR1 2260
Affinity Capture-MS Homo sapiens
63 MLEC 9761
Affinity Capture-MS Homo sapiens
64 METTL7A 25840
Proximity Label-MS Homo sapiens
65 SLC35B1 10237
Affinity Capture-MS Homo sapiens
66 STX18 53407
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
67 CAMLG 819
Two-hybrid Homo sapiens
68 LMAN1 3998
Proximity Label-MS Homo sapiens
69 NUP155 9631
Proximity Label-MS Homo sapiens
70 KIAA1715 80856
Proximity Label-MS Homo sapiens
71 PXMP2  
Proximity Label-MS Homo sapiens
72 DHCR7 1717
Affinity Capture-MS Homo sapiens
73 PANX1 24145
Proximity Label-MS Homo sapiens
74 SCFD1 23256
Affinity Capture-MS Homo sapiens
75 EMD 2010
Proximity Label-MS Homo sapiens
76 MICAL2 9645
Affinity Capture-MS Homo sapiens
77 CD74 972
Affinity Capture-MS Homo sapiens
78 RB1CC1 9821
Affinity Capture-MS Homo sapiens
79 AMFR 267
Affinity Capture-MS Homo sapiens
80 ACACA 31
Affinity Capture-MS Homo sapiens
81 SRSF3 6428
Co-fractionation Homo sapiens
82 DEFB124  
Two-hybrid Homo sapiens
83 PAM16  
Two-hybrid Homo sapiens
84 ASNA1 439
Two-hybrid Homo sapiens
85 CIAO1 9391
Two-hybrid Homo sapiens
86 GID8 54994
Affinity Capture-MS Homo sapiens
87 EFHD1  
Affinity Capture-MS Homo sapiens
88 PTPRE 5791
Affinity Capture-MS Homo sapiens
89 CYB5A 1528
Co-fractionation Homo sapiens
90 PMAIP1  
Affinity Capture-MS Homo sapiens
91 VCP 7415
Affinity Capture-MS Homo sapiens
92 GORASP2 26003
Affinity Capture-MS Homo sapiens
93 RDH11 51109
Affinity Capture-MS Homo sapiens
94 CREB3L1  
Two-hybrid Homo sapiens
95 ZMPSTE24 10269
Affinity Capture-MS Homo sapiens
96 HUWE1 10075
Affinity Capture-MS Homo sapiens
97 DHFRL1  
Proximity Label-MS Homo sapiens
98 PCSK9 255738
Affinity Capture-MS Homo sapiens
99 RNF13 11342
Co-localization Homo sapiens
100 STX5 6811
Affinity Capture-MS Homo sapiens
101 TECR 9524
Affinity Capture-MS Homo sapiens
102 TMEM33 55161
Affinity Capture-MS Homo sapiens
103 DNAJC12  
Affinity Capture-MS Homo sapiens
104 ELOVL5 60481
Proximity Label-MS Homo sapiens
105 DHCR24 1718
Affinity Capture-MS Homo sapiens
106 SEC61B 10952
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
107 SSR4 6748
Affinity Capture-MS Homo sapiens
108 REEP5 7905
Proximity Label-MS Homo sapiens
109 DUSP22  
Affinity Capture-MS Homo sapiens
110 CDS2 8760
Affinity Capture-MS Homo sapiens
111 SEC63 11231
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
112 TMPO 7112
Affinity Capture-MS Homo sapiens
113 C4orf32  
Affinity Capture-MS Homo sapiens
114 RAB29 8934
Affinity Capture-MS Homo sapiens
115 CYP3A4  
Affinity Capture-Western Homo sapiens
116 PTPRCAP 5790
Affinity Capture-MS Homo sapiens
117 TMED9 54732
Affinity Capture-MS Homo sapiens
118 RPN2 6185
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
119 DAD1 1603
Affinity Capture-MS Homo sapiens
120 CANX 821
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
121 TMED3 23423
Affinity Capture-MS Homo sapiens
122 ATL3 25923
Co-fractionation Homo sapiens
123 EMC8 10328
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
124 LRRC59 55379
Proximity Label-MS Homo sapiens
125 LMNB1 4001
Proximity Label-MS Homo sapiens
126 CEPT1 10390
Affinity Capture-MS Homo sapiens
127 B3GNT3 10331
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
128 BCAP31 10134
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
129 HSD3B7 80270
Proximity Label-MS Homo sapiens
130 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
131 STIM1 6786
Proximity Label-MS Homo sapiens
132 MTNR1A  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
133 EGFR 1956
Affinity Capture-MS Homo sapiens
134 FKBP8 23770
Co-fractionation Homo sapiens
135 HSD17B10 3028
Affinity Capture-MS Homo sapiens
136 SLC7A5 8140
Affinity Capture-MS Homo sapiens
137 ARF6 382
Proximity Label-MS Homo sapiens
138 FOXL1  
Proximity Label-MS Homo sapiens
139 NCDN 23154
Affinity Capture-MS Homo sapiens
140 ALDH3A2 224
Affinity Capture-MS Homo sapiens
141 RPN1 6184
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
142 SPCS3 60559
Affinity Capture-MS Homo sapiens
143 CYP2C18  
Affinity Capture-MS Homo sapiens
144 CYP51A1 1595
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
145 SGTB  
Two-hybrid Homo sapiens
146 PRKACA 5566
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
147 CCDC155  
Two-hybrid Homo sapiens
148 EVI2B 2124
Two-hybrid Homo sapiens
149 ARHGAP15 55843
Affinity Capture-MS Homo sapiens
150 FOS 2353
Proximity Label-MS Homo sapiens
151 CNR2  
Affinity Capture-MS Homo sapiens
152 RPA3 6119
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
153 ATP2A1 487
Proximity Label-MS Homo sapiens
154 EMC2 9694
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
155 OSTC 58505
Affinity Capture-MS Homo sapiens
156 RAB9A 9367
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
157 CISD2 493856
Affinity Capture-MS Homo sapiens
158 NCLN 56926
Affinity Capture-MS Homo sapiens
159 DUSP9  
Affinity Capture-MS Homo sapiens
160 CUL7 9820
Affinity Capture-MS Homo sapiens
161 DDRGK1 65992
Affinity Capture-MS Homo sapiens
162 SCD 6319
Affinity Capture-MS Homo sapiens
163 STX4 6810
Proximity Label-MS Homo sapiens
164 VDAC1 7416
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
165 CYP2C9  
Proximity Label-MS Homo sapiens
166 RAB5C 5878
Proximity Label-MS Homo sapiens
167 LMNA 4000
Proximity Label-MS Homo sapiens
168 OSBPL8 114882
Affinity Capture-MS Homo sapiens
169 RTN4 57142
Affinity Capture-MS Homo sapiens
170 PARP16 54956
Affinity Capture-MS Homo sapiens
171 SCCPDH 51097
Affinity Capture-MS Homo sapiens
172 CCDC8  
Affinity Capture-MS Homo sapiens
173 OST4  
Affinity Capture-MS Homo sapiens
174 GBAS 2631
Co-fractionation Homo sapiens
175 AP3S1 1176
Affinity Capture-MS Homo sapiens
176 CYP2C8  
Affinity Capture-Western Homo sapiens
177 LBR 3930
Affinity Capture-MS Homo sapiens
178 NSF 4905
Affinity Capture-MS Homo sapiens
179 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
180 TMED10 10972
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
181 MAGEF1  
Affinity Capture-MS Homo sapiens
182 BKRF1  
Affinity Capture-MS
183 ILF3 3609
Co-fractionation Homo sapiens
184 DNAJC19 131118
Affinity Capture-MS Homo sapiens
185 FBXL6  
Affinity Capture-MS Homo sapiens
186 RTN3 10313
Affinity Capture-MS Homo sapiens
187 FAS 355
Proximity Label-MS Homo sapiens
188 RPA1 6117
Affinity Capture-MS Homo sapiens
189 EMC4 51234
Affinity Capture-MS Homo sapiens
190 NBAS 51594
Affinity Capture-MS Homo sapiens
191 DNAAF5 54919
Affinity Capture-MS Homo sapiens
192 ERLIN2 11160
Affinity Capture-MS Homo sapiens
193 PIGK 10026
Affinity Capture-MS Homo sapiens
194 OTUB1 55611
Affinity Capture-MS Homo sapiens
195 NUP35 129401
Proximity Label-MS Homo sapiens
196 ERGIC1 57222
Proximity Label-MS Homo sapiens
197 ATP2A2 488
Affinity Capture-MS Homo sapiens
198 PTPRO 5800
Affinity Capture-MS Homo sapiens
199 KLF16  
Affinity Capture-MS Homo sapiens
200 RAB4A 5867
Proximity Label-MS Homo sapiens
201 ZW10 9183
Affinity Capture-MS Homo sapiens
202 SFXN1 94081
Affinity Capture-MS Homo sapiens
203 UFL1 23376
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
204 PTPN5  
Affinity Capture-MS Homo sapiens
205 ERGIC2 51290
Proximity Label-MS Homo sapiens
206 SEC62 7095
Proximity Label-MS Homo sapiens
207 B3GAT1  
Proximity Label-MS Homo sapiens
208 C16orf72 29035
Affinity Capture-MS Homo sapiens
209 TOMM5  
Co-fractionation Homo sapiens
210 DNAJB4 11080
Proximity Label-MS Homo sapiens
211 TRIM31  
Affinity Capture-MS Homo sapiens
212 FECH 2235
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
213 SPTLC1 10558
Affinity Capture-MS Homo sapiens
214 ZNF629 23361
Affinity Capture-MS Homo sapiens
215 TMED7 51014
Affinity Capture-MS Homo sapiens
216 STT3B 201595
Affinity Capture-MS Homo sapiens
217 DNAJC1 64215
Proximity Label-MS Homo sapiens
218 KRAS 3845
Proximity Label-MS Homo sapiens
219 HNRNPU 3192
Co-fractionation Homo sapiens
220 C9orf72  
Affinity Capture-MS Homo sapiens
221 GOLM1 51280
Two-hybrid Homo sapiens
222 PAF1 54623
Affinity Capture-MS Homo sapiens
223 CKAP4 10970
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
224 BAG1 573
Affinity Capture-MS Homo sapiens
225 ESYT1 23344
Affinity Capture-MS Homo sapiens
226 SPCS2 9789
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
227 ATP13A1 57130
Affinity Capture-MS Homo sapiens
228 DERL1 79139
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which PGRMC1 is involved
PathwayEvidenceSource
Immune System TAS Reactome
Innate Immune System TAS Reactome
Neutrophil degranulation TAS Reactome





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