Gene description for Abr
Gene name
active BCR-related gene
Gene symbol
Abr
Other names/aliases
-
Species
Mus musculus
Database cross references - Abr
ExoCarta
ExoCarta_109934
Vesiclepedia
VP_109934
Entrez Gene
109934
UniProt
Q5SSL4
Abr identified in exosomes derived from the following tissue/cell type
Colon cancer cells
37309723
Mast cells
17486113
T-cell lymphoma cells
37309723
Gene ontology annotations for Abr
Experiment description of studies that identified Abr in exosomes
1
Experiment ID
907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
Colon cancer cells
Sample name
C26
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
15
MISEV standards
✔
EM
Biophysical techniques
✔
CD63
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
mrna
Identification method
Microarray
PubMed ID
17486113
Organism
Mus musculus Homo sapiens
Experiment description
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors
"Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name
NCB
Publication year
2007
Sample
Mast cells
Sample name
MC9 Bone marrow-derived mast cells HMC-1
Isolation/purification methods
Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.11-1.21 g/mL
Molecules identified in the study
Protein mRNA miRNA
Methods used in the study
Mass spectrometry [MALDI TOF] Western blotting Microarray miRCURY LNA Array
3
Experiment ID
908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
T-cell lymphoma cells
Sample name
EL4
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for Abr
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
MGA
Affinity Capture-MS
Homo sapiens
2
CCAR1
55749
Affinity Capture-MS
Homo sapiens
3
IMPDH2
3615
Affinity Capture-MS
Homo sapiens
4
SMARCC1
6599
Affinity Capture-MS
Homo sapiens
5
MCM3
4172
Affinity Capture-MS
Homo sapiens
6
KCTD12
115207
Affinity Capture-MS
Homo sapiens
7
HAX1
Affinity Capture-MS
Homo sapiens
8
RAC1
5879
FRET
Homo sapiens
9
TOMM40
10452
Affinity Capture-MS
Homo sapiens
10
ATPIF1
93974
Affinity Capture-MS
Homo sapiens
11
CHCHD2
Affinity Capture-MS
Homo sapiens
12
Rac1
19353
Affinity Capture-Western
Mus musculus
13
CKAP4
10970
Affinity Capture-MS
Homo sapiens
14
DOCK4
9732
Affinity Capture-MS
Homo sapiens
15
PRRC2A
7916
Affinity Capture-MS
Homo sapiens
16
Dlg4
Affinity Capture-MS
Mus musculus
Affinity Capture-MS
Mus musculus
17
CHCHD3
54927
Affinity Capture-MS
Homo sapiens
18
BOLA2
552900
Affinity Capture-MS
Homo sapiens
19
PPP1R13L
10848
Affinity Capture-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which Abr is involved