Gene description for PSPC1
Gene name paraspeckle component 1
Gene symbol PSPC1
Other names/aliases PSP1
Species Homo sapiens
 Database cross references - PSPC1
ExoCarta ExoCarta_55269
Vesiclepedia VP_55269
Entrez Gene 55269
HGNC 20320
MIM 612408
UniProt Q8WXF1  
 PSPC1 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
 Gene ontology annotations for PSPC1
Molecular Function
    RNA binding GO:0003723 HDA
    RNA binding GO:0003723 IBA
    RNA binding GO:0003723 IDA
    protein binding GO:0005515 IPI
Biological Process
    activation of innate immune response GO:0002218 IDA
    regulation of DNA-templated transcription GO:0006355 IBA
    regulation of circadian rhythm GO:0042752 ISS
    innate immune response GO:0045087 IEA
    negative regulation of DNA-templated transcription GO:0045892 ISS
    rhythmic process GO:0048511 IEA
    membraneless organelle assembly GO:0140694 IDA
Subcellular Localization
    fibrillar center GO:0001650 IDA
    nucleus GO:0005634 IBA
    nucleoplasm GO:0005654 IDA
    cytoplasm GO:0005737 IEA
    nuclear matrix GO:0016363 IEA
    nuclear speck GO:0016607 IEA
    paraspeckles GO:0042382 IDA
 Experiment description of studies that identified PSPC1 in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 1203
MISEV standards
EM
Biophysical techniques
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
10
Experiment ID 407
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 419
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 419
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 420
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 420
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 405
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 417
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 411
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
18
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
19
Experiment ID 418
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 418
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 413
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 211
MISEV standards
EM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
cytochrome c|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 212
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
Cytochrome C|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
24
Experiment ID 406
MISEV standards
EM
Biophysical techniques
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 415
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 434
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
27
Experiment ID 435
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
28
Experiment ID 408
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 409
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 416
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 410
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for PSPC1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EIF3A 8661
Affinity Capture-MS Homo sapiens
2 WDR6 11180
Affinity Capture-MS Homo sapiens
3 TRMT1L 81627
Affinity Capture-MS Homo sapiens
4 HNRNPA0 10949
Affinity Capture-MS Homo sapiens
5 SKIV2L 6499
Affinity Capture-MS Homo sapiens
6 RPL38 6169
Affinity Capture-MS Homo sapiens
7 EIF3C 8663
Affinity Capture-MS Homo sapiens
8 SRPRB 58477
Affinity Capture-MS Homo sapiens
9 RCL1 10171
Affinity Capture-MS Homo sapiens
10 DDX17 10521
Affinity Capture-MS Homo sapiens
11 ACTC1 70
Proximity Label-MS Homo sapiens
12 THOC7 80145
Affinity Capture-MS Homo sapiens
13 PRPF40A 55660
Affinity Capture-MS Homo sapiens
14 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
15 WDR76  
Affinity Capture-MS Homo sapiens
16 CRNKL1 51340
Affinity Capture-MS Homo sapiens
17 NUP153 9972
Affinity Capture-MS Homo sapiens
18 DRG1 4733
Affinity Capture-MS Homo sapiens
19 CPSF7 79869
Affinity Capture-MS Homo sapiens
20 RPS9 6203
Affinity Capture-MS Homo sapiens
21 KRT31 3881
Two-hybrid Homo sapiens
22 ORC6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 EIF3E 3646
Affinity Capture-MS Homo sapiens
24 RANBP17  
Co-fractionation Homo sapiens
25 EXOSC4 54512
Affinity Capture-MS Homo sapiens
26 Rpl35 66489
Affinity Capture-MS Mus musculus
27 ZNF598 90850
Affinity Capture-MS Homo sapiens
28 MECP2 4204
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 NMT1 4836
Affinity Capture-MS Homo sapiens
30 RPS11 6205
Affinity Capture-MS Homo sapiens
31 CKMT2  
Affinity Capture-MS Homo sapiens
32 NEIL3  
Protein-RNA Homo sapiens
33 KIF14 9928
Affinity Capture-MS Homo sapiens
34 EXOSC9 5393
Affinity Capture-MS Homo sapiens
35 HEXIM1 10614
Affinity Capture-MS Homo sapiens
36 WBP4  
Reconstituted Complex Homo sapiens
37 SRPK2 6733
Affinity Capture-MS Homo sapiens
38 ANKRD17 26057
Affinity Capture-MS Homo sapiens
39 MEPCE 56257
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 TARBP2  
Affinity Capture-MS Homo sapiens
41 RPL19 6143
Affinity Capture-MS Homo sapiens
42 PABPC1 26986
Affinity Capture-MS Homo sapiens
43 OGT 8473
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
44 RPL31 6160
Affinity Capture-MS Homo sapiens
45 SYNCRIP 10492
Affinity Capture-MS Homo sapiens
46 RFC4 5984
Affinity Capture-MS Homo sapiens
47 CCDC22 28952
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 RRP1B 23076
Affinity Capture-MS Homo sapiens
49 SON 6651
Affinity Capture-MS Homo sapiens
50 SND1 27044
Affinity Capture-MS Homo sapiens
51 GTPBP4 23560
Affinity Capture-MS Homo sapiens
52 SRPK1 6732
Affinity Capture-MS Homo sapiens
53 CCNT1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
54 SP100 6672
Affinity Capture-MS Homo sapiens
55 SSR4 6748
Affinity Capture-MS Homo sapiens
56 ZNF326 284695
Affinity Capture-MS Homo sapiens
57 EIF3G 8666
Affinity Capture-MS Homo sapiens
58 AVEN 57099
Affinity Capture-MS Homo sapiens
59 LRRC59 55379
Affinity Capture-MS Homo sapiens
60 CD2BP2 10421
Affinity Capture-MS Homo sapiens
61 ZNF622 90441
Affinity Capture-MS Homo sapiens
62 ACAD11 84129
Affinity Capture-MS Homo sapiens
63 CD274 29126
Affinity Capture-MS Homo sapiens
64 CUL3 8452
Affinity Capture-MS Homo sapiens
65 TOX4  
Affinity Capture-MS Homo sapiens
66 EIF4E 1977
Affinity Capture-MS Homo sapiens
67 EPRS 2058
Affinity Capture-MS Homo sapiens
68 DHX37  
Affinity Capture-MS Homo sapiens
69 MFAP1  
Affinity Capture-MS Homo sapiens
70 RPA3 6119
Proximity Label-MS Homo sapiens
71 EIF2D 1939
Affinity Capture-MS Homo sapiens
72 NDC80 10403
Affinity Capture-MS Homo sapiens
73 TBCA 6902
Co-fractionation Homo sapiens
74 EIF2B1 1967
Affinity Capture-MS Homo sapiens
75 GNL3 26354
Affinity Capture-MS Homo sapiens
76 RPS16 6217
Affinity Capture-MS Homo sapiens
77 NUDT21 11051
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
78 IARS 3376
Affinity Capture-MS Homo sapiens
79 RBM25 58517
Affinity Capture-MS Homo sapiens
80 EIF3I 8668
Affinity Capture-MS Homo sapiens
81 TCERG1 10915
Reconstituted Complex Homo sapiens
82 KPNA6 23633
Affinity Capture-MS Homo sapiens
83 NGEF  
Affinity Capture-MS Homo sapiens
84 TBL3 10607
Affinity Capture-MS Homo sapiens
85 TRA2B 6434
Affinity Capture-MS Homo sapiens
86 PDCD2 5134
Affinity Capture-MS Homo sapiens
87 LARP7 51574
Affinity Capture-MS Homo sapiens
88 RPS24 6229
Affinity Capture-MS Homo sapiens
89 NCL 4691
Affinity Capture-MS Homo sapiens
90 ALYREF 10189
Affinity Capture-MS Homo sapiens
91 HNRNPL 3191
Affinity Capture-MS Homo sapiens
92 ARHGAP36  
Affinity Capture-MS Homo sapiens
93 EIF4B 1975
Affinity Capture-MS Homo sapiens
94 TET3  
Affinity Capture-MS Homo sapiens
95 ZNF768 79724
Affinity Capture-MS Homo sapiens
96 TNN 63923
Co-fractionation Homo sapiens
97 RPL23A 6147
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
98 VAV3 10451
Affinity Capture-MS Homo sapiens
99 ARHGEF10L 55160
Affinity Capture-MS Homo sapiens
100 Eea1  
Affinity Capture-MS Mus musculus
101 SEC61A1 29927
Affinity Capture-MS Homo sapiens
102 EIF4G3 8672
Affinity Capture-MS Homo sapiens
103 SRGAP1 57522
Affinity Capture-MS Homo sapiens
104 EXOSC7 23016
Affinity Capture-MS Homo sapiens
105 NCBP1 4686
Affinity Capture-MS Homo sapiens
106 FAM98A 25940
Affinity Capture-MS Homo sapiens
107 WDR3  
Affinity Capture-MS Homo sapiens
108 ELAVL2 1993
Affinity Capture-MS Homo sapiens
109 EIF2S3 1968
Affinity Capture-MS Homo sapiens
110 EIF3K 27335
Affinity Capture-MS Homo sapiens
111 PPIL4  
Affinity Capture-MS Homo sapiens
112 ARHGAP26 23092
Affinity Capture-MS Homo sapiens
113 CEP170 9859
Affinity Capture-MS Homo sapiens
114 PRPF38A 84950
Affinity Capture-MS Homo sapiens
115 NOP56 10528
Affinity Capture-MS Homo sapiens
116 SRPR 6734
Affinity Capture-MS Homo sapiens
117 ZFR 51663
Affinity Capture-MS Homo sapiens
118 RPL14 9045
Affinity Capture-MS Homo sapiens
119 EIF4A1 1973
Affinity Capture-MS Homo sapiens
120 RSBN1  
Affinity Capture-MS Homo sapiens
121 RPS3 6188
Affinity Capture-MS Homo sapiens
122 RPS18 6222
Affinity Capture-MS Homo sapiens
123 EXOSC2 23404
Affinity Capture-MS Homo sapiens
124 H1FX 8971
Affinity Capture-MS Homo sapiens
125 MRPS23 51649
Affinity Capture-MS Homo sapiens
126 OBSL1 23363
Affinity Capture-MS Homo sapiens
127 DDX6 1656
Affinity Capture-MS Homo sapiens
128 DHX36 170506
Affinity Capture-MS Homo sapiens
129 LARP4B 23185
Affinity Capture-MS Homo sapiens
130 LSM2 57819
Affinity Capture-MS Homo sapiens
131 TTC37 9652
Affinity Capture-MS Homo sapiens
132 PPP5C 5536
Co-fractionation Homo sapiens
133 DDX21 9188
Affinity Capture-MS Homo sapiens
134 NFRKB  
Affinity Capture-MS Homo sapiens
135 RPL4 6124
Affinity Capture-MS Homo sapiens
136 TET2  
Affinity Capture-MS Homo sapiens
137 PEG10 23089
Affinity Capture-MS Homo sapiens
138 KRTAP13-1  
Two-hybrid Homo sapiens
139 CDK13 8621
Affinity Capture-MS Homo sapiens
140 NKRF 55922
Affinity Capture-MS Homo sapiens
141 EXOSC5 56915
Affinity Capture-MS Homo sapiens
142 NOMO3 408050
Affinity Capture-MS Homo sapiens
143 LYAR 55646
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
144 RPLP0 6175
Affinity Capture-MS Homo sapiens
145 RAD21 5885
Affinity Capture-Western Homo sapiens
146 NFX1  
Affinity Capture-MS Homo sapiens
147 KDF1  
Affinity Capture-MS Homo sapiens
148 RSL1D1 26156
Affinity Capture-MS Homo sapiens
149 FAM76B  
Affinity Capture-MS Homo sapiens
150 TET1  
Affinity Capture-MS Homo sapiens
151 ZSCAN5B  
Two-hybrid Homo sapiens
152 RPS2 6187
Affinity Capture-MS Homo sapiens
153 POP1 10940
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
154 RPS7 6201
Affinity Capture-MS Homo sapiens
155 YLPM1 56252
Affinity Capture-MS Homo sapiens
156 EGFR 1956
Affinity Capture-MS Homo sapiens
157 FARP2 9855
Affinity Capture-MS Homo sapiens
158 FUS 2521
Affinity Capture-MS Homo sapiens
159 LARS 51520
Affinity Capture-MS Homo sapiens
160 PIP4K2A 5305
Affinity Capture-MS Homo sapiens
161 TADA2A  
Affinity Capture-MS Homo sapiens
162 MYC  
Affinity Capture-MS Homo sapiens
163 PROSER1  
Affinity Capture-MS Homo sapiens
164 FOCAD 54914
Affinity Capture-MS Homo sapiens
165 NMD3 51068
Affinity Capture-MS Homo sapiens
166 EDF1 8721
Affinity Capture-MS Homo sapiens
167 BMI1  
Affinity Capture-MS Homo sapiens
168 STYX  
Affinity Capture-MS Homo sapiens
169 ADAR 103
Affinity Capture-MS Homo sapiens
170 OSBPL8 114882
Affinity Capture-MS Homo sapiens
171 FTSJ3 117246
Affinity Capture-MS Homo sapiens
172 LARP4 113251
Affinity Capture-MS Homo sapiens
173 EIF3H 8667
Affinity Capture-MS Homo sapiens
174 FAM120A 23196
Affinity Capture-MS Homo sapiens
175 PA2G4 5036
Affinity Capture-MS Homo sapiens
176 RPL13 6137
Affinity Capture-MS Homo sapiens
177 C17orf80 55028
Affinity Capture-MS Homo sapiens
178 PRRC2A 7916
Affinity Capture-MS Homo sapiens
179 PARP1 142
Proximity Label-MS Homo sapiens
180 ILF3 3609
Affinity Capture-MS Homo sapiens
181 TP53 7157
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
182 UBA5 79876
Affinity Capture-MS Homo sapiens
183 FXR1 8087
Affinity Capture-MS Homo sapiens
184 SF3B4 10262
Affinity Capture-MS Homo sapiens
185 SRP19 6728
Affinity Capture-MS Homo sapiens
186 RPS4X 6191
Affinity Capture-MS Homo sapiens
187 C1orf35  
Affinity Capture-MS Homo sapiens
188 CAPRIN1 4076
Affinity Capture-MS Homo sapiens
189 RPS5 6193
Affinity Capture-MS Homo sapiens
190 NIFK 84365
Affinity Capture-MS Homo sapiens
191 YTHDF3  
Affinity Capture-MS Homo sapiens
192 ESR1  
Reconstituted Complex Homo sapiens
193 EIF3J 8669
Affinity Capture-MS Homo sapiens
194 TEFM  
Affinity Capture-MS Homo sapiens
195 YBX3 8531
Affinity Capture-MS Homo sapiens
196 DNAJB4 11080
Co-fractionation Homo sapiens
197 RPL7A 6130
Affinity Capture-MS Homo sapiens
198 DDX42 11325
Affinity Capture-MS Homo sapiens
199 SMAD3 4088
Affinity Capture-MS Homo sapiens
200 EIF5 1983
Affinity Capture-MS Homo sapiens
201 CKAP4 10970
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
202 PRMT1 3276
Affinity Capture-MS Homo sapiens
203 UBE2H 7328
Affinity Capture-MS Homo sapiens
204 HNRNPC 3183
Affinity Capture-MS Homo sapiens
205 RPL26L1 51121
Affinity Capture-MS Homo sapiens
206 EEF1G 1937
Affinity Capture-MS Homo sapiens
207 RPS26 6231
Affinity Capture-MS Homo sapiens
208 GMIP  
Affinity Capture-MS Homo sapiens
209 SDAD1  
Affinity Capture-MS Homo sapiens
210 RPS19 6223
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
211 HNRNPR 10236
Affinity Capture-MS Homo sapiens
212 PPP1R10  
Affinity Capture-MS Homo sapiens
213 RPS6KB2  
Affinity Capture-MS Homo sapiens
214 FAU 2197
Affinity Capture-MS Homo sapiens
215 HNRNPUL2 221092
Affinity Capture-MS Homo sapiens
216 WDR75  
Affinity Capture-MS Homo sapiens
217 CUL7 9820
Affinity Capture-MS Homo sapiens
218 RPL10A 4736
Affinity Capture-MS Homo sapiens
219 CDC16 8881
Affinity Capture-MS Homo sapiens
220 UFM1 51569
Affinity Capture-MS Homo sapiens
221 LLPH  
Affinity Capture-MS Homo sapiens
222 EIF3B 8662
Affinity Capture-MS Homo sapiens
223 LSG1  
Affinity Capture-MS Homo sapiens
224 XRN1 54464
Affinity Capture-MS Homo sapiens
225 CCDC47 57003
Affinity Capture-MS Homo sapiens
226 MTDH 92140
Affinity Capture-MS Homo sapiens
227 ARHGEF15  
Affinity Capture-MS Homo sapiens
228 PABPC4 8761
Affinity Capture-MS Homo sapiens
229 Arhgap1 228359
Affinity Capture-MS Mus musculus
230 BRIX1 55299
Affinity Capture-MS Homo sapiens
231 NF2 4771
Negative Genetic Homo sapiens
232 RPL27 6155
Affinity Capture-MS Homo sapiens
233 NSUN2 54888
Affinity Capture-MS Homo sapiens
234 DLD 1738
Affinity Capture-MS Homo sapiens
235 PNO1 56902
Affinity Capture-MS Homo sapiens
236 FOXC1  
Affinity Capture-MS Homo sapiens
237 CNOT2  
Affinity Capture-MS Homo sapiens
238 RPL9 6133
Affinity Capture-MS Homo sapiens
239 PARK2  
Affinity Capture-MS Homo sapiens
240 RPS10 6204
Affinity Capture-MS Homo sapiens
241 BTF3L4 91408
Affinity Capture-MS Homo sapiens
242 MARS 4141
Affinity Capture-MS Homo sapiens
243 NAA40  
Affinity Capture-MS Homo sapiens
244 SRRT 51593
Affinity Capture-MS Homo sapiens
245 RPL5 6125
Affinity Capture-MS Homo sapiens
246 ABCF2 10061
Affinity Capture-MS Homo sapiens
247 FMR1 2332
Affinity Capture-MS Homo sapiens
248 NTRK1 4914
Affinity Capture-MS Homo sapiens
249 LAS1L 81887
Affinity Capture-MS Homo sapiens
250 U2AF2 11338
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
251 NSRP1  
Affinity Capture-MS Homo sapiens
252 SMAD2 4087
Affinity Capture-MS Homo sapiens
253 RPA4  
Proximity Label-MS Homo sapiens
254 RPLP1 6176
Affinity Capture-MS Homo sapiens
255 DHX9 1660
Affinity Capture-MS Homo sapiens
256 SEC61G 23480
Affinity Capture-MS Homo sapiens
257 HNRNPA3 220988
Affinity Capture-MS Homo sapiens
258 MYBBP1A 10514
Affinity Capture-MS Homo sapiens
259 EIF4A2 1974
Affinity Capture-MS Homo sapiens
260 LARP1 23367
Affinity Capture-MS Homo sapiens
261 HNRNPDL 9987
Affinity Capture-MS Homo sapiens
262 DISC1 27185
Two-hybrid Homo sapiens
263 SF3B2 10992
Affinity Capture-MS Homo sapiens
264 ZAK 51776
Affinity Capture-MS Homo sapiens
265 SPATS2L 26010
Affinity Capture-MS Homo sapiens
266 EXOSC10 5394
Affinity Capture-MS Homo sapiens
267 COMMD8 54951
Affinity Capture-MS Homo sapiens
268 DCAF13 25879
Affinity Capture-MS Homo sapiens
269 RPL21 6144
Affinity Capture-MS Homo sapiens
270 ISG20L2 81875
Affinity Capture-MS Homo sapiens
271 YY1 7528
Affinity Capture-MS Homo sapiens
272 HNRNPA1 3178
Proximity Label-MS Homo sapiens
273 DHX30 22907
Affinity Capture-MS Homo sapiens
274 FAM195B 348262
Affinity Capture-MS Homo sapiens
275 POLR2A 5430
Cross-Linking-MS (XL-MS) Homo sapiens
276 RFC1 5981
Affinity Capture-MS Homo sapiens
277 PDCD4 27250
Affinity Capture-MS Homo sapiens
278 RPL36 25873
Affinity Capture-MS Homo sapiens
279 FXR2 9513
Affinity Capture-MS Homo sapiens
280 RPS13 6207
Affinity Capture-MS Homo sapiens
281 RPS14 6208
Affinity Capture-MS Homo sapiens
282 TOP1 7150
Affinity Capture-MS Homo sapiens
283 RPL22 6146
Affinity Capture-MS Homo sapiens
284 SPAST 6683
Affinity Capture-MS Homo sapiens
285 HDLBP 3069
Affinity Capture-MS Homo sapiens
286 RPL18 6141
Affinity Capture-MS Homo sapiens
287 KTN1 3895
Affinity Capture-MS Homo sapiens
288 TSR1 55720
Affinity Capture-MS Homo sapiens
289 C3orf17  
Affinity Capture-MS Homo sapiens
290 CBX4  
Affinity Capture-MS Homo sapiens
291 EIF2S1 1965
Affinity Capture-MS Homo sapiens
292 TOP2B 7155
Affinity Capture-MS Homo sapiens
293 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
294 RARA 5914
Affinity Capture-MS Homo sapiens
295 RPS25 6230
Affinity Capture-MS Homo sapiens
296 SMN1 6606
Affinity Capture-MS Homo sapiens
297 RPL6 6128
Affinity Capture-MS Homo sapiens
298 RPS21 6227
Affinity Capture-MS Homo sapiens
299 DDX3X 1654
Affinity Capture-MS Homo sapiens
300 PRRC2C 23215
Affinity Capture-MS Homo sapiens
301 MAGEB2 4113
Affinity Capture-MS Homo sapiens
302 MEN1 4221
Affinity Capture-MS Homo sapiens
303 PDHA1 5160
Affinity Capture-MS Homo sapiens
304 HNRNPM 4670
Affinity Capture-MS Homo sapiens
305 MTHFD1 4522
Affinity Capture-MS Homo sapiens
306 PRRC2B  
Affinity Capture-MS Homo sapiens
307 RPL34 6164
Affinity Capture-MS Homo sapiens
308 UFL1 23376
Affinity Capture-MS Homo sapiens
309 MRPS18B 28973
Affinity Capture-MS Homo sapiens
310 RNMTL1  
Affinity Capture-MS Homo sapiens
311 RTCB 51493
Affinity Capture-MS Homo sapiens
312 CIT 11113
Affinity Capture-MS Homo sapiens
313 RPL8 6132
Affinity Capture-MS Homo sapiens
314 C14orf166 51637
Affinity Capture-MS Homo sapiens
315 RPL28 6158
Affinity Capture-MS Homo sapiens
316 RPS27L 51065
Affinity Capture-MS Homo sapiens
317 SERBP1 26135
Affinity Capture-MS Homo sapiens
318 AR 367
Affinity Capture-MS Homo sapiens
319 NOL9 79707
Affinity Capture-MS Homo sapiens
320 DDX56  
Affinity Capture-MS Homo sapiens
321 EP300 2033
Affinity Capture-MS Homo sapiens
322 CASC3  
Affinity Capture-MS Homo sapiens
323 EIF3L 51386
Affinity Capture-MS Homo sapiens
324 GNL2 29889
Affinity Capture-MS Homo sapiens
325 RPSA 3921
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
326 SLFN11 91607
Proximity Label-MS Homo sapiens
327 ARHGAP21 57584
Affinity Capture-MS Homo sapiens
328 IGF2BP1 10642
Affinity Capture-MS Homo sapiens
329 RSBN1L  
Affinity Capture-MS Homo sapiens
330 QARS 5859
Affinity Capture-MS Homo sapiens
331 SCARNA22  
Affinity Capture-RNA Homo sapiens
332 RPS3A 6189
Affinity Capture-MS Homo sapiens
333 RPL30 6156
Affinity Capture-MS Homo sapiens
334 YTHDF1 54915
Affinity Capture-MS Homo sapiens
335 BZW2 28969
Affinity Capture-MS Homo sapiens
336 P4HA2 8974
Affinity Capture-MS Homo sapiens
337 RPL13A 23521
Affinity Capture-MS Homo sapiens
338 KPNB1 3837
Affinity Capture-MS Homo sapiens
339 RPL10 6134
Affinity Capture-MS Homo sapiens
340 RPL15 6138
Affinity Capture-MS Homo sapiens
341 KARS 3735
Affinity Capture-MS Homo sapiens
342 DHX57 90957
Affinity Capture-MS Homo sapiens
343 ELAVL1 1994
Affinity Capture-MS Homo sapiens
344 CCDC124 115098
Affinity Capture-MS Homo sapiens
345 ILF2 3608
Affinity Capture-MS Homo sapiens
346 QSER1  
Affinity Capture-MS Homo sapiens
347 PPP1CC 5501
Affinity Capture-MS Homo sapiens
348 SRP54 6729
Affinity Capture-MS Homo sapiens
349 RPS20 6224
Affinity Capture-MS Homo sapiens
350 PPP1R12A 4659
Affinity Capture-MS Homo sapiens
351 ATXN2L 11273
Affinity Capture-MS Homo sapiens
352 TAF2  
Affinity Capture-MS Homo sapiens
353 FBXW7  
Affinity Capture-MS Homo sapiens
354 C8orf82  
Proximity Label-MS Homo sapiens
355 AGO3  
Affinity Capture-MS Homo sapiens
356 WDR12 55759
Co-fractionation Homo sapiens
357 TRPV5  
Affinity Capture-MS Homo sapiens
358 ABCE1 6059
Affinity Capture-MS Homo sapiens
359 EED  
Affinity Capture-MS Homo sapiens
360 SRP68 6730
Affinity Capture-MS Homo sapiens
361 NR2C1  
Affinity Capture-MS Homo sapiens
362 ARHGAP22 58504
Affinity Capture-MS Homo sapiens
363 CSNK1D 1453
Affinity Capture-MS Homo sapiens
364 COMMD4 54939
Affinity Capture-MS Homo sapiens
365 CCDC86  
Affinity Capture-MS Homo sapiens
366 LSM12 124801
Affinity Capture-MS Homo sapiens
367 EIF1B  
Affinity Capture-MS Homo sapiens
368 LZTFL1 54585
Co-fractionation Homo sapiens
369 GEMIN5 25929
Affinity Capture-MS Homo sapiens
370 PPP1CA 5499
Affinity Capture-MS Homo sapiens
371 ASCC1 51008
Affinity Capture-MS Homo sapiens
372 NONO 4841
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
373 STAU1 6780
Affinity Capture-MS Homo sapiens
374 LRIF1  
Two-hybrid Homo sapiens
375 DDX5 1655
Affinity Capture-MS Homo sapiens
376 IFI16 3428
Affinity Capture-MS Homo sapiens
377 RPL27A 6157
Affinity Capture-MS Homo sapiens
378 TPP2 7174
Affinity Capture-MS Homo sapiens
379 DDX1 1653
Affinity Capture-MS Homo sapiens
380 TATDN1 83940
Co-fractionation Homo sapiens
381 DLG1 1739
Affinity Capture-MS Homo sapiens
382 ZC3H15 55854
Affinity Capture-MS Homo sapiens
383 RPS15A 6210
Affinity Capture-MS Homo sapiens
384 CEBPA  
Protein-peptide Homo sapiens
385 USP10 9100
Affinity Capture-MS Homo sapiens
386 WDR82 80335
Affinity Capture-MS Homo sapiens
387 SFPQ 6421
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
388 ASCC3 10973
Affinity Capture-MS Homo sapiens
389 PRPF4B 8899
Affinity Capture-MS Homo sapiens
390 RPLP2 6181
Affinity Capture-MS Homo sapiens
391 CDK9 1025
Affinity Capture-MS Homo sapiens
392 EIF4G1 1981
Affinity Capture-MS Homo sapiens
393 RPL35 11224
Affinity Capture-MS Homo sapiens
394 DHX29 54505
Affinity Capture-MS Homo sapiens
395 COMMD2 51122
Affinity Capture-MS Homo sapiens
396 RPS8 6202
Affinity Capture-MS Homo sapiens
397 CTTN 2017
Affinity Capture-MS Homo sapiens
398 RPL3 6122
Affinity Capture-MS Homo sapiens
399 RPL7 6129
Affinity Capture-MS Homo sapiens
400 HIP1R 9026
Co-fractionation Homo sapiens
401 SART1 9092
Affinity Capture-MS Homo sapiens
402 MAP7D1 55700
Affinity Capture-MS Homo sapiens
403 EIF4H 7458
Co-fractionation Homo sapiens
404 SSR3 6747
Affinity Capture-MS Homo sapiens
405 COMMD6 170622
Affinity Capture-MS Homo sapiens
406 FIP1L1 81608
Affinity Capture-MS Homo sapiens
407 EIF2S2 8894
Affinity Capture-MS Homo sapiens
408 RPL11 6135
Affinity Capture-MS Homo sapiens
409 RARS 5917
Affinity Capture-MS Homo sapiens
410 EIF3M 10480
Affinity Capture-MS Homo sapiens
411 EIF3D 8664
Affinity Capture-MS Homo sapiens
412 YTHDC2 64848
Affinity Capture-MS Homo sapiens
413 GLUD1 2746
Affinity Capture-MS Homo sapiens
414 RRBP1 6238
Affinity Capture-MS Homo sapiens
415 CPSF6 11052
Affinity Capture-MS Homo sapiens
416 NUFIP2 57532
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
417 HNRNPA2B1 3181
Affinity Capture-MS Homo sapiens
418 ATXN2 6311
Affinity Capture-MS Homo sapiens
419 RPS15 6209
Affinity Capture-MS Homo sapiens
420 SRP72 6731
Affinity Capture-MS Homo sapiens
421 EIF4A3 9775
Affinity Capture-MS Homo sapiens
422 NUP35 129401
Proximity Label-MS Homo sapiens
423 RPL39 6170
Affinity Capture-MS Homo sapiens
424 NUP50 10762
Affinity Capture-MS Homo sapiens
425 LRPAP1 4043
Affinity Capture-MS Homo sapiens
426 UPF1 5976
Affinity Capture-MS Homo sapiens
427 RPS6 6194
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
428 XRCC6 2547
Co-fractionation Homo sapiens
429 EIF5A 1984
Affinity Capture-MS Homo sapiens
430 HNRNPU 3192
Affinity Capture-MS Homo sapiens
431 GNB2L1 10399
Affinity Capture-MS Homo sapiens
432 METTL17  
Affinity Capture-MS Homo sapiens
433 ARHGAP35 2909
Affinity Capture-MS Homo sapiens
434 RPL17 6139
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which PSPC1 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here