Gene description for HIST1H3E
Gene name histone cluster 1, H3e
Gene symbol HIST1H3E
Other names/aliases H3.1
H3/d
H3FD
Species Homo sapiens
 Database cross references - HIST1H3E
ExoCarta ExoCarta_8353
Vesiclepedia VP_8353
Entrez Gene 8353
HGNC 4769
MIM 602813
UniProt P68431  
 HIST1H3E identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Neuroblastoma cells 25944692    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Squamous carcinoma cells 20124223    
Thymus 23844026    
 Gene ontology annotations for HIST1H3E
Molecular Function
    DNA binding GO:0003677 IEA
    protein binding GO:0005515 IDA
    protein binding GO:0005515 IPI
    structural constituent of chromatin GO:0030527 IEA
    cadherin binding GO:0045296 HDA
    protein heterodimerization activity GO:0046982 IEA
Biological Process
    chromatin organization GO:0006325 NAS
    nucleosome assembly GO:0006334 IDA
    nucleosome assembly GO:0006334 IMP
    gene expression GO:0010467 IDA
    telomere organization GO:0032200 TAS
    epigenetic regulation of gene expression GO:0040029 IDA
Subcellular Localization
    nucleosome GO:0000786 IDA
    nucleosome GO:0000786 IPI
    extracellular region GO:0005576 TAS
    nucleus GO:0005634 HDA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    membrane GO:0016020 HDA
    protein-containing complex GO:0032991 IDA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified HIST1H3E in exosomes
1
Experiment ID 282
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
2
Experiment ID 283
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
3
Experiment ID 285
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
4
Experiment ID 286
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
5
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
6
Experiment ID 138
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name DU145 - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
7
Experiment ID 141
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name VCaP - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
8
Experiment ID 143
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name LNCaP - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
9
Experiment ID 144
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name C4-2 - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
10
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for HIST1H3E
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RALY 22913
Affinity Capture-MS Homo sapiens
2 RPS12 6206
Affinity Capture-MS Homo sapiens
3 HIST2H2BE 8349
Co-purification Homo sapiens
4 RPS6KA5 9252
Biochemical Activity Homo sapiens
5 MCM7 4176
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
6 SMC3 9126
Affinity Capture-MS Homo sapiens
7 GATAD2B 57459
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 HIST2H2AB 317772
Affinity Capture-MS Homo sapiens
9 CNBP 7555
Affinity Capture-MS Homo sapiens
10 RPS17 6218
Affinity Capture-MS Homo sapiens
11 XPC  
Affinity Capture-MS Homo sapiens
12 RCL1 10171
Affinity Capture-MS Homo sapiens
13 RPS14 6208
Affinity Capture-MS Homo sapiens
14 MCM3 4172
Affinity Capture-MS Homo sapiens
15 COPRS  
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
16 THRAP3 9967
Affinity Capture-MS Homo sapiens
17 DBN1 1627
Affinity Capture-MS Homo sapiens
18 RPL37A 6168
Affinity Capture-MS Homo sapiens
19 SMARCE1 6605
Affinity Capture-MS Homo sapiens
20 HIST1H2BB 3018
Affinity Capture-MS Homo sapiens
21 H2AFY 9555
Affinity Capture-MS Homo sapiens
22 RPL14 9045
Affinity Capture-MS Homo sapiens
23 PRPF3  
Affinity Capture-MS Homo sapiens
24 STK36  
Co-purification Homo sapiens
25 PRKDC 5591
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
26 SF3B5 83443
Affinity Capture-MS Homo sapiens
27 CENPA  
Affinity Capture-MS Homo sapiens
28 HIST1H4F 8361
Affinity Capture-Western Homo sapiens
29 DAXX  
Affinity Capture-MS Homo sapiens
30 TOP2A 7153
Affinity Capture-MS Homo sapiens
31 RPS20 6224
Affinity Capture-MS Homo sapiens
32 SNRNP70 6625
Affinity Capture-MS Homo sapiens
33 CBX1 10951
Affinity Capture-MS Homo sapiens
34 SSRP1 6749
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 CHAF1A  
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 MCM2 4171
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 SPIN1  
Affinity Capture-MS Homo sapiens
38 SF3B1 23451
Affinity Capture-MS Homo sapiens
39 BRD7  
Affinity Capture-MS Homo sapiens
40 RPL24 6152
Affinity Capture-MS Homo sapiens
41 NPM1 4869
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
42 SRRM2 23524
Affinity Capture-MS Homo sapiens
43 SNRPC 6631
Affinity Capture-MS Homo sapiens
44 KHDRBS1 10657
Affinity Capture-MS Homo sapiens
45 MCM6 4175
Affinity Capture-MS Homo sapiens
46 SF3A2 8175
Affinity Capture-MS Homo sapiens
47 HIST4H4 121504
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
48 CWC15  
Affinity Capture-MS Homo sapiens
49 ZNF644  
Affinity Capture-MS Homo sapiens
50 SLMO1  
Co-purification Homo sapiens
51 ITGA4 3676
Affinity Capture-MS Homo sapiens
52 SNRPD3 6634
Affinity Capture-MS Homo sapiens
53 RPL29 6159
Affinity Capture-MS Homo sapiens
54 SETD1B 23067
Biochemical Activity Homo sapiens
55 PHF1  
Reconstituted Complex Homo sapiens
56 PFKFB3 5209
Affinity Capture-MS Homo sapiens
57 C11orf84  
Affinity Capture-MS Homo sapiens
58 ASF1A 25842
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
59 CCAR1 55749
Affinity Capture-MS Homo sapiens
60 RPL19 6143
Affinity Capture-MS Homo sapiens
61 MTA1 9112
Affinity Capture-MS Homo sapiens
62 RPS26 6231
Affinity Capture-MS Homo sapiens
63 EEF1A1 1915
Affinity Capture-MS Homo sapiens
64 C1QBP 708
Affinity Capture-MS Homo sapiens
65 PPM1B 5495
Affinity Capture-MS Homo sapiens
66 MTA2 9219
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
67 RPL27 6155
Affinity Capture-MS Homo sapiens
68 TCOF1 6949
Affinity Capture-MS Homo sapiens
69 PHF10  
Affinity Capture-MS Homo sapiens
70 PCNP 57092
Affinity Capture-MS Homo sapiens
71 RBBP7 5931
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 HMG20A  
Affinity Capture-MS Homo sapiens
73 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
74 DDX21 9188
Affinity Capture-MS Homo sapiens
75 MRE11A 4361
Affinity Capture-MS Homo sapiens
76 PSMD4 5710
Affinity Capture-MS Homo sapiens
77 RPS28 6234
Affinity Capture-MS Homo sapiens
78 HIST1H2AA 221613
Affinity Capture-MS Homo sapiens
79 RPS10 6204
Affinity Capture-MS Homo sapiens
80 HIST1H2AG 8969
Affinity Capture-MS Homo sapiens
81 YPEL5 51646
Affinity Capture-MS Homo sapiens
82 NBN 4683
Affinity Capture-MS Homo sapiens
83 DNMT3A 1788
Reconstituted Complex Homo sapiens
Far Western Homo sapiens
84 ACIN1 22985
Affinity Capture-MS Homo sapiens
85 TRIM24  
Co-crystal Structure Homo sapiens
Protein-peptide Homo sapiens
86 CBX3 11335
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
87 SMARCA4 6597
Affinity Capture-MS Homo sapiens
88 PABPC1 26986
Affinity Capture-MS Homo sapiens
89 TIMELESS  
Affinity Capture-MS Homo sapiens
90 RAN 5901
Co-purification Homo sapiens
91 TRIM21 6737
Affinity Capture-MS Homo sapiens
92 RPL31 6160
Affinity Capture-MS Homo sapiens
93 ACTL6A 86
Affinity Capture-MS Homo sapiens
94 CBX5 23468
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
95 RBM17 84991
Affinity Capture-MS Homo sapiens
96 GTF3C2  
Affinity Capture-MS Homo sapiens
97 HIST2H4A 8370
Affinity Capture-MS Homo sapiens
98 RPL36 25873
Affinity Capture-MS Homo sapiens
99 HIST2H2AC 8338
Co-purification Homo sapiens
100 HIST1H1C 3006
Affinity Capture-MS Homo sapiens
101 RPL27A 6157
Affinity Capture-MS Homo sapiens
102 SMC1A 8243
Affinity Capture-MS Homo sapiens
103 MBD3 53615
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
104 CSTB 1476
Affinity Capture-MS Homo sapiens
105 PRPF31 26121
Affinity Capture-MS Homo sapiens
106 ACTG1 71
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
107 RAD21 5885
Affinity Capture-MS Homo sapiens
108 HIST1H2AB 8335
Affinity Capture-MS Homo sapiens
109 U2SURP 23350
Affinity Capture-MS Homo sapiens
110 RBM10  
Affinity Capture-MS Homo sapiens
111 MAT2A 4144
Affinity Capture-MS Homo sapiens
112 BCLAF1 9774
Affinity Capture-MS Homo sapiens
113 LIMA1 51474
Affinity Capture-MS Homo sapiens
114 TONSL  
Affinity Capture-Western Homo sapiens
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
115 SF3B2 10992
Affinity Capture-MS Homo sapiens
116 RPL32 6161
Affinity Capture-MS Homo sapiens
117 BMS1  
Affinity Capture-MS Homo sapiens
118 NASP 4678
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
119 RPL7A 6130
Affinity Capture-MS Homo sapiens
120 TMPO 7112
Affinity Capture-MS Homo sapiens
121 CHERP 10523
Affinity Capture-MS Homo sapiens
122 UBR7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
123 SMARCD1 6602
Affinity Capture-MS Homo sapiens
124 MGA  
Affinity Capture-MS Homo sapiens
125 RPL35 11224
Affinity Capture-MS Homo sapiens
126 CAMSAP3  
Affinity Capture-MS Homo sapiens
127 RLIM 51132
Affinity Capture-MS Homo sapiens
128 RPS7 6201
Affinity Capture-MS Homo sapiens
129 E2F7  
Affinity Capture-MS Homo sapiens
130 GADD45GIP1  
Affinity Capture-MS Homo sapiens
131 MCM4 4173
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
132 RBBP4 5928
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
133 SART1 9092
Affinity Capture-MS Homo sapiens
134 SPTBN1 6711
Affinity Capture-MS Homo sapiens
135 ATRX 546
Affinity Capture-MS Homo sapiens
136 MTA3 57504
Affinity Capture-MS Homo sapiens
137 SF3A1 10291
Affinity Capture-MS Homo sapiens
138 HIST1H3B 8358
Affinity Capture-MS Homo sapiens
139 PRMT5 10419
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
140 SLAIN2  
Affinity Capture-MS Homo sapiens
141 SERBP1 26135
Affinity Capture-MS Homo sapiens
142 DNAJC9 23234
Two-hybrid Homo sapiens
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
143 TMOD3 29766
Affinity Capture-MS Homo sapiens
144 TOP1 7150
Affinity Capture-MS Homo sapiens
145 PHF5A 84844
Affinity Capture-MS Homo sapiens
146 HIRA  
Affinity Capture-MS Homo sapiens
147 HSPA4 3308
Co-purification Homo sapiens
148 MMS22L  
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
149 FBLIM1 54751
Affinity Capture-MS Homo sapiens
150 SF3B3 23450
Affinity Capture-MS Homo sapiens
151 RPS18 6222
Affinity Capture-MS Homo sapiens
152 HSPD1 3329
Co-purification Homo sapiens
153 HAT1 8520
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
154 NEPNP  
Co-purification Homo sapiens
155 LMNA 4000
Co-purification Homo sapiens
156 RPL26 6154
Affinity Capture-MS Homo sapiens
157 SUPT16H 11198
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
158 TAF4 6874
Affinity Capture-MS Homo sapiens
159 ILF3 3609
Affinity Capture-MS Homo sapiens
160 XRCC5 7520
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
161 SNRPD2 6633
Affinity Capture-MS Homo sapiens
162 DSP 1832
Co-purification Homo sapiens
163 WDR77 79084
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
164 GATAD2A 54815
Affinity Capture-MS Homo sapiens
165 KRT18 3875
Co-purification Homo sapiens
166 MYCBP 26292
Affinity Capture-MS Homo sapiens
167 RPS27A 6233
Affinity Capture-MS Homo sapiens
168 SPTAN1 6709
Affinity Capture-MS Homo sapiens
169 PRRC2A 7916
Affinity Capture-MS Homo sapiens
170 PARP1 142
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
171 ARID2  
Affinity Capture-MS Homo sapiens
172 HDGF 3068
Affinity Capture-MS Homo sapiens
173 CHAF1B  
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
174 CCDC86  
Affinity Capture-MS Homo sapiens
175 RBM25 58517
Affinity Capture-MS Homo sapiens
176 ASF1B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
177 MRPS28  
Affinity Capture-MS Homo sapiens
178 STK38 11329
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
179 MCM5 4174
Affinity Capture-MS Homo sapiens
180 SMARCC1 6599
Affinity Capture-MS Homo sapiens
181 NSRP1  
Affinity Capture-MS Homo sapiens
182 DNMT1 1786
Affinity Capture-MS Homo sapiens
183 RPS21 6227
Affinity Capture-MS Homo sapiens
184 PDHA1 5160
Affinity Capture-MS Homo sapiens
185 PBRM1 55193
Affinity Capture-MS Homo sapiens
186 ERH 2079
Affinity Capture-MS Homo sapiens
187 HDAC1 3065
Affinity Capture-MS Homo sapiens
188 CHD4 1108
Affinity Capture-MS Homo sapiens
189 STK38L 23012
Affinity Capture-MS Homo sapiens
190 GTF2I 2969
Affinity Capture-MS Homo sapiens
191 BUB3 9184
Affinity Capture-MS Homo sapiens
192 BOLA2 552900
Affinity Capture-MS Homo sapiens
193 SPTY2D1  
Affinity Capture-MS Homo sapiens
194 HNRNPK 3190
Affinity Capture-MS Homo sapiens
195 SSBP1 6742
Co-purification Homo sapiens
196 RAD50 10111
Affinity Capture-MS Homo sapiens
197 PCNA 5111
Co-purification Homo sapiens
198 RPL39 6170
Affinity Capture-MS Homo sapiens
199 OTUD4  
Affinity Capture-MS Homo sapiens
200 PARP2  
Affinity Capture-MS Homo sapiens
201 HNRNPL 3191
Affinity Capture-MS Homo sapiens
202 SUPT6H 6830
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
203 EIF4B 1975
Affinity Capture-MS Homo sapiens
204 IPO4 79711
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
205 YBX3 8531
Affinity Capture-MS Homo sapiens
206 FLNA 2316
Affinity Capture-MS Homo sapiens
207 SF3A3 10946
Affinity Capture-MS Homo sapiens
208 GLYR1 84656
Affinity Capture-MS Homo sapiens
209 XRCC6 2547
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
210 PRPF4 9128
Affinity Capture-MS Homo sapiens
211 UHRF1 29128
Affinity Capture-MS Homo sapiens
212 CKAP4 10970
Affinity Capture-MS Homo sapiens
213 SNRPA1 6627
Affinity Capture-MS Homo sapiens
214 HSPA5 3309
Affinity Capture-MS Homo sapiens
215 SRSF7 6432
Affinity Capture-MS Homo sapiens
216 RPL17 6139
Affinity Capture-MS Homo sapiens
217 SMARCC2 6601
Affinity Capture-MS Homo sapiens
218 PFKFB2 5208
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which HIST1H3E is involved
PathwayEvidenceSource
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 TAS Reactome
Activation of anterior HOX genes in hindbrain development during early embryogenesis IEA Reactome
Activation of HOX genes during differentiation IEA Reactome
Amyloid fiber formation TAS Reactome
Assembly of the ORC complex at the origin of replication TAS Reactome
Assembly of the pre-replicative complex TAS Reactome
B-WICH complex positively regulates rRNA expression TAS Reactome
Cell Cycle IEA Reactome
Cell Cycle TAS Reactome
Cell Cycle, Mitotic TAS Reactome
Cellular responses to stimuli TAS Reactome
Cellular responses to stress TAS Reactome
Cellular Senescence TAS Reactome
Chromatin modifications during the maternal to zygotic transition (MZT) IEA Reactome
Chromatin modifying enzymes TAS Reactome
Chromatin modifying enzymes IEA Reactome
Chromatin organization TAS Reactome
Chromatin organization IEA Reactome
Condensation of Prophase Chromosomes TAS Reactome
Cytokine Signaling in Immune system TAS Reactome
Cytokine Signaling in Immune system IEA Reactome
Defective pyroptosis TAS Reactome
Developmental Biology IEA Reactome
Disease TAS Reactome
Diseases of programmed cell death TAS Reactome
DNA methylation IEA Reactome
DNA Replication TAS Reactome
DNA Replication Pre-Initiation TAS Reactome
Epigenetic regulation by WDR5-containing histone modifying complexes IEA Reactome
Epigenetic regulation by WDR5-containing histone modifying complexes TAS Reactome
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes IEA Reactome
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes TAS Reactome
Epigenetic regulation of gene expression TAS Reactome
Epigenetic regulation of gene expression IEA Reactome
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes IEA Reactome
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes TAS Reactome
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression IEA Reactome
ESR-mediated signaling TAS Reactome
Estrogen-dependent gene expression TAS Reactome
Factors involved in megakaryocyte development and platelet production TAS Reactome
Formation of the beta-catenin:TCF transactivating complex TAS Reactome
Gene expression (Transcription) TAS Reactome
Gene expression (Transcription) IEA Reactome
Gene Silencing by RNA TAS Reactome
Generic Transcription Pathway TAS Reactome
Generic Transcription Pathway IEA Reactome
HATs acetylate histones TAS Reactome
HATs acetylate histones IEA Reactome
HCMV Early Events TAS Reactome
HCMV Infection TAS Reactome
HCMV Late Events TAS Reactome
HDACs deacetylate histones TAS Reactome
HDMs demethylate histones TAS Reactome
Hemostasis TAS Reactome
Immune System TAS Reactome
Immune System IEA Reactome
Infectious disease TAS Reactome
Interleukin-7 signaling TAS Reactome
Interleukin-7 signaling IEA Reactome
M Phase TAS Reactome
Maternal to zygotic transition (MZT) IEA Reactome
Meiosis IEA Reactome
Meiotic recombination IEA Reactome
Metabolism of proteins TAS Reactome
Mitotic Prophase TAS Reactome
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis IEA Reactome
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis TAS Reactome
Negative epigenetic regulation of rRNA expression TAS Reactome
Negative epigenetic regulation of rRNA expression IEA Reactome
NoRC negatively regulates rRNA expression IEA Reactome
NoRC negatively regulates rRNA expression TAS Reactome
Oxidative Stress Induced Senescence TAS Reactome
PKMTs methylate histone lysines TAS Reactome
Positive epigenetic regulation of rRNA expression TAS Reactome
Positive epigenetic regulation of rRNA expression IEA Reactome
PRC2 methylates histones and DNA TAS Reactome
Pre-NOTCH Expression and Processing IEA Reactome
Pre-NOTCH Transcription and Translation IEA Reactome
Regulation of endogenous retroelements TAS Reactome
Regulation of endogenous retroelements IEA Reactome
Regulation of endogenous retroelements by KRAB-ZFP proteins TAS Reactome
Regulation of endogenous retroelements by KRAB-ZFP proteins IEA Reactome
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) IEA Reactome
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex TAS Reactome
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex IEA Reactome
Reproduction IEA Reactome
RHO GTPase Effectors TAS Reactome
RHO GTPases activate PKNs TAS Reactome
RMTs methylate histone arginines TAS Reactome
RNA Polymerase I Promoter Clearance TAS Reactome
RNA Polymerase I Promoter Escape TAS Reactome
RNA Polymerase I Promoter Opening TAS Reactome
RNA Polymerase I Transcription TAS Reactome
RNA Polymerase II Transcription TAS Reactome
RNA Polymerase II Transcription IEA Reactome
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function TAS Reactome
RUNX1 regulates transcription of genes involved in differentiation of HSCs IEA Reactome
Senescence-Associated Secretory Phenotype (SASP) TAS Reactome
Signal Transduction TAS Reactome
Signal Transduction IEA Reactome
Signaling by Interleukins TAS Reactome
Signaling by Interleukins IEA Reactome
Signaling by NOTCH IEA Reactome
Signaling by Nuclear Receptors TAS Reactome
Signaling by Rho GTPases TAS Reactome
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 TAS Reactome
Signaling by WNT TAS Reactome
SIRT1 negatively regulates rRNA expression TAS Reactome
TCF dependent signaling in response to WNT TAS Reactome
Transcriptional regulation by RUNX1 TAS Reactome
Transcriptional regulation by RUNX1 IEA Reactome
Transcriptional regulation by small RNAs TAS Reactome
Transcriptional regulation of granulopoiesis IEA Reactome
Viral Infection Pathways TAS Reactome





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