Gene description for CYB5B
Gene name cytochrome b5 type B (outer mitochondrial membrane)
Gene symbol CYB5B
Other names/aliases CYB5-M
CYPB5M
OMB5
Species Homo sapiens
 Database cross references - CYB5B
ExoCarta ExoCarta_80777
Vesiclepedia VP_80777
Entrez Gene 80777
HGNC 24374
MIM 611964
UniProt O43169  
 CYB5B identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Mesenchymal stem cells 36408942    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for CYB5B
Molecular Function
    protein binding GO:0005515 IPI
    enzyme activator activity GO:0008047 IEA
    heme binding GO:0020037 IBA
    heme binding GO:0020037 IDA
    metal ion binding GO:0046872 IEA
    nitrite reductase (NO-forming) activity GO:0050421 IDA
Biological Process
    xenobiotic metabolic process GO:0006805 ISS
    nitric oxide biosynthetic process GO:0006809 IDA
    response to oxidative stress GO:0006979 ISS
Subcellular Localization
    mitochondrial outer membrane GO:0005741 IBA
    mitochondrial outer membrane GO:0005741 TAS
    endoplasmic reticulum membrane GO:0005789 TAS
    membrane GO:0016020 HDA
    intracellular membrane-bounded organelle GO:0043231 IBA
    nitric-oxide synthase complex GO:1903958 IDA
 Experiment description of studies that identified CYB5B in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
15
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for CYB5B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DPY19L1 23333
Affinity Capture-MS Homo sapiens
2 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
3 ATR  
Affinity Capture-MS Homo sapiens
4 CLDN7 1366
Two-hybrid Homo sapiens
5 HSD17B11 51170
Proximity Label-MS Homo sapiens
6 UQCRFS1 7386
Co-fractionation Homo sapiens
7 CLCN7 1186
Affinity Capture-MS Homo sapiens
8 MTCH1 23787
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 ISYNA1 51477
Co-fractionation Homo sapiens
10 COIL  
Proximity Label-MS Homo sapiens
11 C6orf57  
Two-hybrid Homo sapiens
12 METTL7A 25840
Proximity Label-MS Homo sapiens
13 TSC2 7249
Affinity Capture-MS Homo sapiens
14 NOP9 161424
Affinity Capture-MS Homo sapiens
15 DNM1L 10059
Affinity Capture-MS Homo sapiens
16 FRMD3  
Two-hybrid Homo sapiens
17 USP24 23358
Affinity Capture-MS Homo sapiens
18 QKI 9444
Affinity Capture-MS Homo sapiens
19 ATP12A 479
Affinity Capture-MS Homo sapiens
20 MFSD5  
Two-hybrid Homo sapiens
21 SPNS1 83985
Co-fractionation Homo sapiens
22 CSE1L 1434
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
23 CD33 945
Two-hybrid Homo sapiens
24 COG2 22796
Affinity Capture-MS Homo sapiens
25 NDUFA4 4697
Affinity Capture-MS Homo sapiens
26 RTN4 57142
Affinity Capture-MS Homo sapiens
27 APP 351
Reconstituted Complex Homo sapiens
28 KIAA1429 25962
Affinity Capture-MS Homo sapiens
29 FIS1 51024
Proximity Label-MS Homo sapiens
30 STX1A 6804
Two-hybrid Homo sapiens
31 SGPL1 8879
Affinity Capture-MS Homo sapiens
32 VARS 7407
Co-fractionation Homo sapiens
33 CYB5R1 51706
Co-fractionation Homo sapiens
34 BRAT1 221927
Affinity Capture-MS Homo sapiens
35 OTULIN 90268
Affinity Capture-MS Homo sapiens
36 MUC1 4582
Two-hybrid Homo sapiens
37 SLC10A6  
Two-hybrid Homo sapiens
38 COQ9  
Affinity Capture-MS Homo sapiens
39 ORC5  
Affinity Capture-MS Homo sapiens
40 MLST8 64223
Affinity Capture-MS Homo sapiens
41 SSR1 6745
Proximity Label-MS Homo sapiens
42 MARCH5  
Proximity Label-MS Homo sapiens
43 SQLE 6713
Affinity Capture-MS Homo sapiens
44 SRP14 6727
Co-fractionation Homo sapiens
45 XPO7 23039
Affinity Capture-MS Homo sapiens
46 HELLS 3070
Affinity Capture-MS Homo sapiens
47 PGRMC2 10424
Co-fractionation Homo sapiens
48 RPN2 6185
Proximity Label-MS Homo sapiens
49 HIATL1 84641
Two-hybrid Homo sapiens
50 TMEM192 201931
Affinity Capture-MS Homo sapiens
51 CCDC47 57003
Co-fractionation Homo sapiens
52 UTP20 27340
Affinity Capture-MS Homo sapiens
53 MXRA7 439921
Co-fractionation Homo sapiens
54 ALCAM 214
Co-fractionation Homo sapiens
55 BTAF1 9044
Affinity Capture-MS Homo sapiens
56 KIR2DL3  
Two-hybrid Homo sapiens
57 ARFGEF2 10564
Affinity Capture-MS Homo sapiens
58 CLN8 2055
Two-hybrid Homo sapiens
59 GNPAT 8443
Affinity Capture-MS Homo sapiens
60 TFRC 7037
Co-fractionation Homo sapiens
61 BTNL9  
Two-hybrid Homo sapiens
62 PDS5B 23047
Affinity Capture-MS Homo sapiens
63 CLASP2 23122
Affinity Capture-MS Homo sapiens
64 FAS 355
Proximity Label-MS Homo sapiens
65 LMAN1 3998
Proximity Label-MS Homo sapiens
66 CCT2 10576
Co-fractionation Homo sapiens
67 KIAA1715 80856
Proximity Label-MS Homo sapiens
68 BSG 682
Co-fractionation Homo sapiens
69 KIAA0391  
Affinity Capture-MS Homo sapiens
70 MTCH2 23788
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 EMC10 284361
Co-fractionation Homo sapiens
72 COX15 1355
Affinity Capture-MS Homo sapiens
73 EMD 2010
Proximity Label-MS Homo sapiens
74 INTS5 80789
Affinity Capture-MS Homo sapiens
75 TMX1 81542
Co-fractionation Homo sapiens
76 REEP4  
Two-hybrid Homo sapiens
77 PRKCSH 5589
Co-fractionation Homo sapiens
78 STOM 2040
Two-hybrid Homo sapiens
79 TMEM165 55858
Co-fractionation Homo sapiens
80 DCUN1D5 84259
Affinity Capture-MS Homo sapiens
81 GBF1 8729
Affinity Capture-MS Homo sapiens
82 SPARC 6678
Co-fractionation Homo sapiens
83 MCAM 4162
Co-fractionation Homo sapiens
84 RRBP1 6238
Cross-Linking-MS (XL-MS) Homo sapiens
85 TMEM139  
Two-hybrid Homo sapiens
86 PUM1 9698
Affinity Capture-MS Homo sapiens
87 DNAJC5 80331
Co-fractionation Homo sapiens
88 C12orf49  
Negative Genetic Homo sapiens
89 UCHL5 51377
Affinity Capture-MS Homo sapiens
90 ATM 472
Affinity Capture-MS Homo sapiens
91 TNPO2 30000
Affinity Capture-MS Homo sapiens
92 PDS5A 23244
Affinity Capture-MS Homo sapiens
93 VCP 7415
Affinity Capture-MS Homo sapiens
94 ACTN4 81
Co-fractionation Homo sapiens
95 CKAP5 9793
Affinity Capture-MS Homo sapiens
96 TNPO3 23534
Affinity Capture-MS Homo sapiens
97 RAB2A 5862
Proximity Label-MS Homo sapiens
98 CREB3  
Two-hybrid Homo sapiens
99 PDZK1IP1 10158
Two-hybrid Homo sapiens
100 MARCH8  
Two-hybrid Homo sapiens
101 RPN1 6184
Proximity Label-MS Homo sapiens
102 NCAPG 64151
Affinity Capture-MS Homo sapiens
103 UQCRH 7388
Co-fractionation Homo sapiens
104 COG5 10466
Affinity Capture-MS Homo sapiens
105 RHOT2 89941
Proximity Label-MS Homo sapiens
106 ELOVL5 60481
Proximity Label-MS Homo sapiens
107 MFF 56947
Two-hybrid Homo sapiens
108 GJB5  
Two-hybrid Homo sapiens
109 SEC61B 10952
Proximity Label-MS Homo sapiens
110 ATP6V1E1 529
Co-fractionation Homo sapiens
111 SYNJ2BP 55333
Co-fractionation Homo sapiens
112 TMEM35  
Two-hybrid Homo sapiens
113 ENO1 2023
Affinity Capture-RNA Homo sapiens
114 DUSP22  
Affinity Capture-MS Homo sapiens
115 ACTN1 87
Co-fractionation Homo sapiens
116 C15orf48  
Affinity Capture-MS Homo sapiens
117 PLAA 9373
Affinity Capture-MS Homo sapiens
118 C4orf32  
Affinity Capture-MS Homo sapiens
119 FNDC9  
Two-hybrid Homo sapiens
120 QSOX1 5768
Affinity Capture-MS Homo sapiens
121 EMC3 55831
Co-fractionation Homo sapiens
122 TMX3 54495
Co-fractionation Homo sapiens
123 AIFM1 9131
Proximity Label-MS Homo sapiens
124 CANX 821
Co-fractionation Homo sapiens
125 TARBP1 6894
Affinity Capture-MS Homo sapiens
126 MCCC2 64087
Affinity Capture-MS Homo sapiens
127 GLMN 11146
Affinity Capture-MS Homo sapiens
128 ATP1A1 476
Co-fractionation Homo sapiens
129 SLC44A1 23446
Affinity Capture-MS Homo sapiens
130 NPTN 27020
Co-fractionation Homo sapiens
131 SYMPK 8189
Affinity Capture-MS Homo sapiens
132 TMEM41A  
Two-hybrid Homo sapiens
133 BCAP31 10134
Proximity Label-MS Homo sapiens
134 GDE1 51573
Affinity Capture-MS Homo sapiens
135 NR3C1 2908
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
136 BNIP3L  
Two-hybrid Homo sapiens
137 ATRIP  
Affinity Capture-MS Homo sapiens
138 HNRNPA1 3178
Co-fractionation Homo sapiens
139 ATP1B3 483
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
140 KIAA1524 57650
Affinity Capture-MS Homo sapiens
141 CORO1C 23603
Co-fractionation Homo sapiens
142 SLC30A5 64924
Affinity Capture-MS Homo sapiens
143 OCIAD1 54940
Proximity Label-MS Homo sapiens
144 NXF1 10482
Affinity Capture-RNA Homo sapiens
145 XPO6 23214
Affinity Capture-MS Homo sapiens
146 GPR152  
Two-hybrid Homo sapiens
147 FAM209A 200232
Two-hybrid Homo sapiens
148 PHB2 11331
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
149 NCEH1 57552
Affinity Capture-MS Homo sapiens
150 XPO4 64328
Affinity Capture-MS Homo sapiens
151 FAM134C 162427
Two-hybrid Homo sapiens
152 CD79A  
Two-hybrid Homo sapiens
153 TMEM237 65062
Two-hybrid Homo sapiens
154 RPA3 6119
Proximity Label-MS Homo sapiens
155 SEC31A 22872
Co-fractionation Homo sapiens
156 ATP2A1 487
Proximity Label-MS Homo sapiens
157 EMC2 9694
Co-fractionation Homo sapiens
158 CPLX4  
Two-hybrid Homo sapiens
159 MTOR 2475
Affinity Capture-MS Homo sapiens
160 RAB9A 9367
Proximity Label-MS Homo sapiens
161 FOCAD 54914
Affinity Capture-MS Homo sapiens
162 PPAPDC1A  
Two-hybrid Homo sapiens
163 KCNK5  
Two-hybrid Homo sapiens
164 ZW10 9183
Affinity Capture-MS Homo sapiens
165 DUSP9  
Affinity Capture-MS Homo sapiens
166 DHFRL1  
Proximity Label-MS Homo sapiens
167 AHNAK2 113146
Two-hybrid Homo sapiens
168 KIAA0368 23392
Affinity Capture-MS Homo sapiens
169 THADA 63892
Affinity Capture-MS Homo sapiens
170 TSR1 55720
Co-fractionation Homo sapiens
171 PEX3 8504
Proximity Label-MS Homo sapiens
172 HIP1R 9026
Affinity Capture-MS Homo sapiens
173 THY1 7070
Co-fractionation Homo sapiens
174 AKAP1 8165
Proximity Label-MS Homo sapiens
175 MLEC 9761
Co-fractionation Homo sapiens
176 SCCPDH 51097
Affinity Capture-MS Homo sapiens
177 ACBD5 91452
Proximity Label-MS Homo sapiens
178 ATP6V1H 51606
Affinity Capture-MS Homo sapiens
179 FLVCR1 28982
Affinity Capture-MS Homo sapiens
180 MBOAT7 79143
Affinity Capture-MS Homo sapiens
181 MRPL42  
Co-fractionation Homo sapiens
182 FASN 2194
Positive Genetic Homo sapiens
183 NDUFAF2  
Two-hybrid Homo sapiens
184 TBRG4 9238
Affinity Capture-MS Homo sapiens
185 PRAF2 11230
Affinity Capture-MS Homo sapiens
186 FBXL6  
Affinity Capture-MS Homo sapiens
187 TOR1AIP2 163590
Co-fractionation Homo sapiens
188 COG1 9382
Affinity Capture-MS Homo sapiens
189 SLC16A2  
Two-hybrid Homo sapiens
190 KIAA1586  
Affinity Capture-MS Homo sapiens
191 BOD1  
Affinity Capture-MS Homo sapiens
192 M6PR 4074
Co-fractionation Homo sapiens
193 LRBA 987
Affinity Capture-MS Homo sapiens
194 BCKDHA 593
Co-fractionation Homo sapiens
195 TMCC3  
Affinity Capture-MS Homo sapiens
196 DNAAF5 54919
Affinity Capture-MS Homo sapiens
197 TMEM86B  
Two-hybrid Homo sapiens
198 NDUFA12 55967
Co-fractionation Homo sapiens
199 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
200 USP22 23326
Affinity Capture-MS Homo sapiens
201 EBP  
Two-hybrid Homo sapiens
202 VPS8 23355
Affinity Capture-MS Homo sapiens
203 HNRNPA3 220988
Co-fractionation Homo sapiens
204 ERGIC1 57222
Proximity Label-MS Homo sapiens
205 TIMELESS  
Affinity Capture-MS Homo sapiens
206 STOML2 30968
Co-fractionation Homo sapiens
207 KNTC1 9735
Affinity Capture-MS Homo sapiens
208 COG6 57511
Affinity Capture-MS Homo sapiens
209 NCAPD2 9918
Affinity Capture-MS Homo sapiens
210 MOV10 4343
Affinity Capture-RNA Homo sapiens
211 SEC62 7095
Proximity Label-MS Homo sapiens
212 GOLGA5 9950
Affinity Capture-MS Homo sapiens
213 STX3 6809
Co-fractionation Homo sapiens
214 POMK  
Co-fractionation Homo sapiens
215 TMEM38B  
Affinity Capture-MS Homo sapiens
216 CYB5R3 1727
Co-fractionation Homo sapiens
217 HSDL1 83693
Affinity Capture-MS Homo sapiens
218 EVA1B 55194
Co-fractionation Homo sapiens
219 RAB5C 5878
Proximity Label-MS Homo sapiens
220 CYCS 54205
Co-fractionation Homo sapiens
221 CKAP4 10970
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
222 COG7 91949
Affinity Capture-MS Homo sapiens
223 SCARB2 950
Co-fractionation Homo sapiens
224 INTS1 26173
Affinity Capture-MS Homo sapiens
225 FAM210B  
Two-hybrid Homo sapiens
226 IPO11 51194
Affinity Capture-MS Homo sapiens
227 KIAA1919  
Two-hybrid Homo sapiens
228 SLC3A2 6520
Co-fractionation Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here