Gene description for PIP4K2A
Gene name phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
Gene symbol PIP4K2A
Other names/aliases PI5P4KA
PIP5K2A
PIP5KII-alpha
PIP5KIIA
PIPK
Species Homo sapiens
 Database cross references - PIP4K2A
ExoCarta ExoCarta_5305
Vesiclepedia VP_5305
Entrez Gene 5305
HGNC 8997
MIM 603140
UniProt P48426  
 PIP4K2A identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells 36408942    
Neuroblastoma cells 25944692    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Thymus 23844026    
 Gene ontology annotations for PIP4K2A
Molecular Function
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 IDA
    1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 NAS
    1-phosphatidylinositol-5-phosphate 4-kinase activity GO:0016309 IBA
    1-phosphatidylinositol-5-phosphate 4-kinase activity GO:0016309 IDA
    protein homodimerization activity GO:0042803 IDA
Biological Process
    regulation of autophagy GO:0010506 IMP
    regulation of autophagy GO:0010506 ISS
    megakaryocyte development GO:0035855 IEA
    negative regulation of insulin receptor signaling pathway GO:0046627 IMP
    phosphatidylinositol phosphate biosynthetic process GO:0046854 IBA
    autophagosome-lysosome fusion GO:0061909 ISS
    vesicle-mediated cholesterol transport GO:0090119 IMP
    1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process GO:1902635 IDA
    positive regulation of autophagosome assembly GO:2000786 IMP
Subcellular Localization
    photoreceptor outer segment GO:0001750 IEA
    photoreceptor inner segment GO:0001917 IEA
    nucleoplasm GO:0005654 TAS
    lysosome GO:0005764 ISS
    autophagosome GO:0005776 IMP
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
 Experiment description of studies that identified PIP4K2A in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
6
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
8
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
10
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 255
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name G1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 256
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 260
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
16
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
17
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
21
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
22
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PIP4K2A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RPSA 3921
Affinity Capture-MS Homo sapiens
2 PIN1 5300
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 UBE2H 7328
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 SLIT2 9353
Affinity Capture-MS Homo sapiens
5 ATPIF1 93974
Affinity Capture-MS Homo sapiens
6 FAM98A 25940
Affinity Capture-MS Homo sapiens
7 HOXA5  
Affinity Capture-MS Homo sapiens
8 NOS1AP  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 RPL30 6156
Affinity Capture-MS Homo sapiens
10 PRPF38B 55119
Affinity Capture-MS Homo sapiens
11 EIF3K 27335
Affinity Capture-MS Homo sapiens
12 PPIL4  
Affinity Capture-MS Homo sapiens
13 PRPF38A 84950
Affinity Capture-MS Homo sapiens
14 PNISR  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 EPB41L5 57669
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 GTF2F1 2962
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 ARL6IP4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 GPALPP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 BRD2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 CSNK2A1 1457
Co-fractionation Homo sapiens
21 PRPF3  
Affinity Capture-MS Homo sapiens
22 CHD8 57680
Affinity Capture-MS Homo sapiens
23 CCDC9  
Affinity Capture-MS Homo sapiens
24 AFF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 PPP1R10  
Affinity Capture-MS Homo sapiens
26 WDR26 80232
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 SRSF8 10929
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 ATG4C  
Affinity Capture-MS Homo sapiens
29 CAB39 51719
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 TCEB3 6924
Affinity Capture-MS Homo sapiens
31 CAPZB 832
Co-fractionation Homo sapiens
32 DDX23 9416
Co-fractionation Homo sapiens
33 Pip4k2c  
Affinity Capture-MS Mus musculus
34 RNPS1 10921
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 AFF4 27125
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 NOLC1 9221
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 LUC7L2 51631
Affinity Capture-MS Homo sapiens
38 H1FX 8971
Cross-Linking-MS (XL-MS) Homo sapiens
39 C18orf25 147339
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 NFKBIL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 SCRIB 23513
Affinity Capture-MS Homo sapiens
42 CPSF7 79869
Affinity Capture-MS Homo sapiens
43 SRRM2 23524
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 PIP4K2B 8396
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 SUN2 25777
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 TULP3 7289
Affinity Capture-MS Homo sapiens
47 PDIA6 10130
Affinity Capture-MS Homo sapiens
48 NUSAP1 51203
Affinity Capture-MS Homo sapiens
49 AP3M1 26985
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 PPRC1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 MECP2 4204
Affinity Capture-MS Homo sapiens
52 ARHGAP22 58504
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 TACO1  
Affinity Capture-MS Homo sapiens
54 MLLT1 4298
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 CSNK2B 1460
Co-fractionation Homo sapiens
56 TP53BP1 7158
Affinity Capture-MS Homo sapiens
57 PRNP 5621
Affinity Capture-MS Homo sapiens
58 EPB41L3 23136
Affinity Capture-MS Homo sapiens
59 RPS23 6228
Affinity Capture-MS Homo sapiens
60 BRPF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
61 TCOF1 6949
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
62 EAF2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 JMJD6 23210
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
64 PIP4K2C 79837
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
65 PRPF8 10594
Co-fractionation Homo sapiens
66 IPO9 55705
Co-fractionation Homo sapiens
67 CUL4B 8450
Affinity Capture-MS Homo sapiens
68 MEPCE 56257
Affinity Capture-MS Homo sapiens
69 STRADA 92335
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 MEX3C 51320
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 ACIN1 22985
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 RTF1 23168
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
73 MEIS3  
Two-hybrid Homo sapiens
74 RPS6KB1 6198
Biochemical Activity Homo sapiens
75 IWS1  
Affinity Capture-MS Homo sapiens
76 ST6GAL1 6480
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
77 RAD18  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
78 SPRR2E  
Affinity Capture-MS Homo sapiens
79 NSRP1  
Affinity Capture-MS Homo sapiens
80 UBTF 7343
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 CSNK1E 1454
Affinity Capture-MS Homo sapiens
82 GPBP1L1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
83 EHBP1L1 254102
Co-fractionation Homo sapiens
84 AP3B1 8546
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
85 BRD4 23476
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
86 AFF3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
87 GTPBP4 23560
Affinity Capture-MS Homo sapiens
88 CCNT1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
89 CHD9 80205
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
90 LARP1 23367
Co-fractionation Homo sapiens
91 ELL2 22936
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
92 CXCR4 7852
Affinity Capture-MS Homo sapiens
93 RAB11FIP1 80223
Affinity Capture-MS Homo sapiens
94 AHCYL1 10768
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
95 PNN 5411
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
96 LAMP1 3916
Proximity Label-MS Homo sapiens
97 CD6 923
Affinity Capture-MS Homo sapiens
98 SETD2  
Affinity Capture-MS Homo sapiens
99 MADD 8567
Affinity Capture-MS Homo sapiens
100 DCAF13 25879
Affinity Capture-MS Homo sapiens
101 CTTN 2017
Affinity Capture-MS Homo sapiens
102 YY1 7528
Affinity Capture-MS Homo sapiens
103 FAM90A1  
Affinity Capture-MS Homo sapiens
104 TMEM194A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
105 ELL  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
106 NAF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
107 SLTM 79811
Affinity Capture-MS Homo sapiens
108 CCDC85A  
Affinity Capture-MS Homo sapiens
109 ELL3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
110 DDX42 11325
Affinity Capture-MS Homo sapiens
111 MEX3B 84206
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
112 SPEN 23013
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
113 RPA3 6119
Proximity Label-MS Homo sapiens
114 PHF6  
Affinity Capture-MS Homo sapiens
115 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
116 RPS14 6208
Affinity Capture-MS Homo sapiens
117 GSTK1 373156
Two-hybrid Homo sapiens
118 CLASRP  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
119 PRPF4 9128
Affinity Capture-MS Homo sapiens
120 C12orf43  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
121 GPATCH8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
122 MTMR1 8776
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
123 RFWD3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
124 SBF1 6305
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
125 LYAR 55646
Affinity Capture-MS Homo sapiens
126 CA2 760
Affinity Capture-MS Homo sapiens
127 BRD3 8019
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
128 DIP2C 22982
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
129 XRCC5 7520
Co-fractionation Homo sapiens
130 NKAP 79576
Affinity Capture-MS Homo sapiens
131 DNAJC13 23317
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
132 PIP5K1A 8394
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
133 PRICKLE3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
134 GRK5 2869
Affinity Capture-MS Homo sapiens
135 NUDT21 11051
Affinity Capture-MS Homo sapiens
136 ARRB2 409
Affinity Capture-MS Homo sapiens
137 GLUD1 2746
Affinity Capture-MS Homo sapiens
138 ZNF428  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
139 MTPN 136319
Co-fractionation Homo sapiens
140 UBE2O 63893
Affinity Capture-MS Homo sapiens
141 ZRANB2 9406
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
142 MAX  
Affinity Capture-MS Homo sapiens
143 RRP1B 23076
Affinity Capture-MS Homo sapiens
144 RPS21 6227
Affinity Capture-MS Homo sapiens
145 CCDC102A 92922
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
146 C9orf114  
Affinity Capture-MS Homo sapiens
147 PPIG 9360
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
148 CXXC1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
149 KANK1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
150 NUFIP2 57532
Affinity Capture-MS Homo sapiens
151 PLCD3 113026
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
152 EDEM1  
Affinity Capture-MS Homo sapiens
153 SKP1 6500
Co-fractionation Homo sapiens
154 KNOP1 400506
Affinity Capture-MS Homo sapiens
155 LENG8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
156 LZTS2 84445
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
157 C1orf35  
Affinity Capture-MS Homo sapiens
158 TAF2  
Affinity Capture-MS Homo sapiens
159 SETD1B 23067
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
160 AHCYL2 23382
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
161 TMA16  
Affinity Capture-MS Homo sapiens
162 HDGFRP2 84717
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
163 EDC4 23644
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
164 LRPAP1 4043
Affinity Capture-MS Homo sapiens
165 SP100 6672
Affinity Capture-MS Homo sapiens
166 SF3B4 10262
Affinity Capture-MS Homo sapiens
167 EAF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
168 ZCCHC10  
Affinity Capture-MS Homo sapiens
169 STK11 6794
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
170 MLLT3 4300
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
171 STRADB  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
172 CWC22 57703
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
173 PSPC1 55269
Affinity Capture-MS Homo sapiens
174 CKAP4 10970
Affinity Capture-MS Homo sapiens
175 PTCH1  
Affinity Capture-MS Homo sapiens
176 C11orf31  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
177 DDX56  
Affinity Capture-MS Homo sapiens
178 RANBP2 5903
Cross-Linking-MS (XL-MS) Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here