Gene description for RRP1B
Gene name ribosomal RNA processing 1B
Gene symbol RRP1B
Other names/aliases KIAA0179
Species Homo sapiens
 Database cross references - RRP1B
ExoCarta ExoCarta_23076
Entrez Gene 23076
HGNC 23818
MIM 610654
UniProt Q14684  
 RRP1B identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells 20124223    
 Gene ontology annotations for RRP1B
Molecular Function
    poly(A) RNA binding GO:0044822 IDA
Biological Process
    negative regulation of phosphatase activity GO:0010923 IDA
    rRNA processing GO:0006364 IEA
Subcellular Localization
    cytosol GO:0005829 IDA
    heterochromatin GO:0000792 IEA
    preribosome, small subunit precursor GO:0030688 IEA
    euchromatin GO:0000791 IEA
    nucleolus GO:0005730 IDA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified RRP1B in exosomes
Experiment ID 191
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RRP1B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PPP1CA 5499
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which RRP1B is involved
No pathways found

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