Gene description for YY1
Gene name	YY1 transcription factor
Gene symbol	YY1
Other names/aliases	DELTA INO80S NF-E1 UCRBP YIN-YANG-1
Species	Homo sapiens
Database cross references - YY1
ExoCarta	ExoCarta_7528
Vesiclepedia	VP_7528
Entrez Gene	7528
HGNC	12856
MIM	600013
UniProt	P25490
YY1 identified in sEVs derived from the following tissue/cell type
Endothelial cells	26027894

Gene ontology annotations for YY1

Molecular Function     four-way junction DNA binding GO:0000400 IDA     transcription cis-regulatory region binding GO:0000976 IDA     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IDA     DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 IBA     DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 IDA     cis-regulatory region sequence-specific DNA binding GO:0000987 IDA     cis-regulatory region sequence-specific DNA binding GO:0000987 IMP     DNA-binding transcription repressor activity GO:0001217 TAS     DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227 IDA     DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227 ISS     DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 IDA     DNA binding GO:0003677 IDA     chromatin binding GO:0003682 IEA     RNA binding GO:0003723 IDA     protein binding GO:0005515 IPI     SMAD binding GO:0046332 IMP     metal ion binding GO:0046872 IEA     DNA-binding transcription factor binding GO:0140297 IPI     sequence-specific double-stranded DNA binding GO:1990837 IDA Biological Process     negative regulation of transcription by RNA polymerase II GO:0000122 IDA     negative regulation of transcription by RNA polymerase II GO:0000122 IDA     telomere maintenance GO:0000723 ISO     double-strand break repair via homologous recombination GO:0000724 IMP     regulation of DNA replication GO:0006275 IMP     regulation of DNA repair GO:0006282 ISO     chromatin remodeling GO:0006338 IDA     regulation of transcription by RNA polymerase II GO:0006357 IBA     regulation of transcription by RNA polymerase II GO:0006357 IDA     RNA localization GO:0006403 IEA     DNA damage response GO:0006974 IMP     spermatogenesis GO:0007283 IEA     anterior/posterior pattern specification GO:0009952 IEA     response to UV-C GO:0010225 IMP     positive regulation of gene expression GO:0010628 IEA     negative regulation of gene expression GO:0010629 IMP     B cell differentiation GO:0030183 IEA     negative regulation of interferon-beta production GO:0032688 IDA     regulation of chromosome organization GO:0033044 IMP     cellular response to UV GO:0034644 IMP     response to prostaglandin F GO:0034696 IEA     positive regulation of DNA repair GO:0045739 ISO     positive regulation of DNA-templated transcription GO:0045893 IMP     positive regulation of transcription by RNA polymerase II GO:0045944 IC     regulation of embryonic development GO:0045995 ISO     camera-type eye morphogenesis GO:0048593 IEA     regulation of cell cycle GO:0051726 IMP     regulation of DNA strand elongation GO:0060382 IMP     negative regulation of cell growth involved in cardiac muscle cell development GO:0061052 IEA     cellular response to interleukin-1 GO:0071347 IEA     immunoglobulin heavy chain V-D-J recombination GO:0071707 IEA     negative regulation of miRNA transcription GO:1902894 IEA     positive regulation of telomere maintenance in response to DNA damage GO:1904507 ISO Subcellular Localization     chromatin GO:0000785 IBA     nucleus GO:0005634 IDA     nucleus GO:0005634 IMP     nucleoplasm GO:0005654 TAS     transcription regulator complex GO:0005667 IBA     chromatin silencing complex GO:0005677 IEA     nuclear matrix GO:0016363 IEA     Ino80 complex GO:0031011 IDA     PcG protein complex GO:0031519 IBA