Gene description for KPNA6
Gene name karyopherin alpha 6 (importin alpha 7)
Gene symbol KPNA6
Other names/aliases IPOA7
Species Homo sapiens
 Database cross references - KPNA6
ExoCarta ExoCarta_23633
Entrez Gene 23633
HGNC 6399
MIM 610563
UniProt O60684  
 KPNA6 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for KPNA6
Molecular Function
    protein binding GO:0005515 IPI
    protein transporter activity GO:0008565 IEA
Biological Process
    NLS-bearing protein import into nucleus GO:0006607 TAS
    maternal process involved in female pregnancy GO:0060135 IEA
    positive regulation of transcription from RNA polymerase II promoter GO:0045944 IEA
Subcellular Localization
    membrane GO:0016020 IDA
    cytoplasm GO:0005737 IEA
    nucleus GO:0005634 IEA
 Experiment description of studies that identified KPNA6 in exosomes
Experiment ID 217
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for KPNA6
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RELB  
Affinity Capture-MS Homo sapiens
2 KPNB1 3837
Reconstituted Complex Homo sapiens
3 SPOP  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which KPNA6 is involved
No pathways found

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