Experiment description of studies that identified GNL2 in exosomes

1 Experiment ID 224 MISEV standards ✔ EM|AFM Biophysical techniques ✔ Alix|TSG101|CD63|CD81 Enriched markers ✔ GOLGA2 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25944692     Organism Homo sapiens Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S" Journal name Oncotarget Publication year 2015 Sample Neuroblastoma cells Sample name SH-SY5Y Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.10 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting

Protein-protein interactions for GNL2

Protein Interactor ExoCarta ID Identification method PubMed Species 1 IWS1   Affinity Capture-MS Homo sapiens 2 RPL11 6135 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 3 CDC14B 8555 Proximity Label-MS Homo sapiens 4 SRP19 6728 Affinity Capture-MS Homo sapiens 5 MLLT4 4301 Affinity Capture-MS Homo sapiens 6 ZNF668   Affinity Capture-MS Homo sapiens 7 RPSAP58 388524 Affinity Capture-MS Homo sapiens 8 UBE2H 7328 Affinity Capture-MS Homo sapiens 9 RPL26L1 51121 Affinity Capture-MS Homo sapiens 10 RSL1D1 26156 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 11 DNAJC9 23234 Proximity Label-MS Homo sapiens 12 SET 6418 Affinity Capture-MS Homo sapiens 13 DNAJC8 22826 Proximity Label-MS Homo sapiens 14 RPS3A 6189 Affinity Capture-MS Homo sapiens 15 SPATS2   Affinity Capture-MS Homo sapiens 16 TCEB3 6924 Affinity Capture-MS Homo sapiens 17 RPL30 6156 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 18 SRPK2 6733 Affinity Capture-MS Homo sapiens 19 MRPS27 23107 Affinity Capture-MS Homo sapiens 20 HIST1H1D 3007 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 21 LHX2   Proximity Label-MS Homo sapiens 22 RPL13A 23521 Affinity Capture-MS Homo sapiens 23 RPL37A 6168 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 24 THAP3   Affinity Capture-MS Homo sapiens 25 NOP56 10528 Proximity Label-MS Homo sapiens 26 RBMXL1   Affinity Capture-MS Homo sapiens 27 RPS19 6223 Affinity Capture-MS Homo sapiens 28 RPL10 6134 Affinity Capture-MS Homo sapiens 29 CHCHD1   Proximity Label-MS Homo sapiens 30 ADD3 120 Affinity Capture-MS Homo sapiens 31 RPL14 9045 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 32 PNMAL1   Affinity Capture-MS Homo sapiens 33 CAND1 55832 Affinity Capture-MS Homo sapiens 34 FGF3   Affinity Capture-MS Homo sapiens 35 RBM15B   Affinity Capture-MS Homo sapiens 36 SRP72 6731 Affinity Capture-MS Homo sapiens 37 SNIP1   Affinity Capture-MS Homo sapiens 38 APP 351 Reconstituted Complex Homo sapiens Reconstituted Complex Homo sapiens 39 CENPA   Proximity Label-MS Homo sapiens 40 DNAJB6 10049 Proximity Label-MS Homo sapiens 41 USP36   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 42 KIF20B   Affinity Capture-MS Homo sapiens 43 CUL7 9820 Affinity Capture-MS Homo sapiens 44 DDX23 9416 Proximity Label-MS Homo sapiens 45 GPATCH4 54865 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 46 ETV3   Proximity Label-MS Homo sapiens 47 ADARB1 104 Affinity Capture-MS Homo sapiens 48 PRR11   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 49 RBM28 55131 Affinity Capture-MS Homo sapiens 50 RPL7A 6130 Affinity Capture-MS Homo sapiens 51 TFAM 7019 Affinity Capture-MS Homo sapiens 52 GTF2F2 2963 Affinity Capture-MS Homo sapiens 53 GTF2F1 2962 Affinity Capture-MS Homo sapiens 54 CDK11B 984 Affinity Capture-MS Homo sapiens 55 PRPF38B 55119 Affinity Capture-MS Homo sapiens 56 WDR74 54663 Co-fractionation Homo sapiens 57 RRP12 23223 Affinity Capture-MS Homo sapiens 58 MRPS5 64969 Affinity Capture-MS Homo sapiens 59 METAP2 10988 Affinity Capture-MS Homo sapiens 60 PRC1 9055 Affinity Capture-MS Homo sapiens 61 MRPS23 51649 Affinity Capture-MS Homo sapiens 62 MRPS24 64951 Affinity Capture-MS Homo sapiens 63 NPM1 4869 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 64 ANOS1 3730 Affinity Capture-MS Homo sapiens 65 ZGPAT   Affinity Capture-MS Homo sapiens 66 RPS8 6202 Affinity Capture-MS Homo sapiens 67 BRPF3   Affinity Capture-MS Homo sapiens 68 POLR1E   Proximity Label-MS Homo sapiens 69 ZNF2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 70 RPS9 6203 Affinity Capture-MS Homo sapiens 71 SRP14 6727 Affinity Capture-MS Homo sapiens 72 SRSF3 6428 Affinity Capture-MS Homo sapiens 73 NFATC2IP   Affinity Capture-MS Homo sapiens 74 PRKRA 8575 Affinity Capture-MS Homo sapiens 75 SRP68 6730 Affinity Capture-MS Homo sapiens 76 LEO1 123169 Affinity Capture-MS Homo sapiens 77 DDX18 8886 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 78 RRP8   Affinity Capture-MS Homo sapiens 79 FBL 2091 Proximity Label-MS Homo sapiens 80 MTDH 92140 Affinity Capture-MS Homo sapiens 81 ZNF346   Affinity Capture-MS Homo sapiens 82 MRPS7 51081 Affinity Capture-MS Homo sapiens 83 MECP2 4204 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 84 Eif3a 13669 Affinity Capture-MS Mus musculus 85 MYCN   Affinity Capture-MS Homo sapiens 86 RBM42   Affinity Capture-MS Homo sapiens 87 OASL 8638 Affinity Capture-MS Homo sapiens 88 C12orf43   Affinity Capture-MS Homo sapiens 89 C11orf57   Affinity Capture-MS Homo sapiens 90 OBSL1 23363 Affinity Capture-MS Homo sapiens 91 RBM8A 9939 Affinity Capture-MS Homo sapiens 92 KIF14 9928 Affinity Capture-MS Homo sapiens 93 LIN28A   Affinity Capture-MS Homo sapiens 94 STRBP 55342 Affinity Capture-MS Homo sapiens 95 KLF16   Proximity Label-MS Homo sapiens 96 MRPS35 60488 Affinity Capture-MS Homo sapiens 97 KIFC1 3833 Affinity Capture-MS Homo sapiens 98 MRPS25 64432 Affinity Capture-MS Homo sapiens 99 ING4   Affinity Capture-MS Homo sapiens 100 DDX21 9188 Affinity Capture-MS Homo sapiens 101 LIN28B   Affinity Capture-MS Homo sapiens 102 MRPS26 64949 Affinity Capture-MS Homo sapiens 103 PINX1   Affinity Capture-MS Homo sapiens 104 RPL4 6124 Affinity Capture-MS Homo sapiens 105 MRPS34 65993 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 106 RBM19 9904 Affinity Capture-MS Homo sapiens 107 ZBTB47   Affinity Capture-MS Homo sapiens 108 RBM4B   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 109 YBX2 51087 Affinity Capture-MS Homo sapiens 110 BLM 641 Affinity Capture-MS Homo sapiens 111 MCM10 55388 Affinity Capture-MS Homo sapiens 112 SRSF6 6431 Affinity Capture-MS Homo sapiens 113 PURG   Affinity Capture-MS Homo sapiens 114 ZBTB48   Affinity Capture-MS Homo sapiens 115 RPL5 6125 Affinity Capture-MS Homo sapiens 116 HIST1H2AM 8336 Affinity Capture-MS Homo sapiens 117 RPL18A 6142 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 118 ZCCHC17   Affinity Capture-MS Homo sapiens 119 ADD2 119 Affinity Capture-MS Homo sapiens 120 Srp72   Affinity Capture-MS Mus musculus 121 NUMB 8650 Affinity Capture-MS Homo sapiens 122 RPS10 6204 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 123 NTRK1 4914 Affinity Capture-MS Homo sapiens 124 RPL31 6160 Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 125 IFI16 3428 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 126 HIST1H1E 3008 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 127 REXO4   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 128 TJP2 9414 Affinity Capture-MS Homo sapiens 129 DICER1   Affinity Capture-MS Homo sapiens 130 HIST1H2BG 8339 Proximity Label-MS Homo sapiens 131 NOB1   Co-fractionation Homo sapiens 132 REPS2   Co-fractionation Homo sapiens 133 UTP11L   Affinity Capture-MS Homo sapiens 134 SNRNP27   Affinity Capture-MS Homo sapiens 135 HECTD1 25831 Affinity Capture-MS Homo sapiens 136 RPLP0 6175 Affinity Capture-MS Homo sapiens 137 SRPK3   Affinity Capture-MS Homo sapiens 138 MAGEB2 4113 Affinity Capture-MS Homo sapiens 139 RANBP6 26953 Affinity Capture-MS Homo sapiens 140 CDX1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 141 MYBBP1A 10514 Affinity Capture-MS Homo sapiens 142 GTPBP4 23560 Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens 143 GLTSCR2   Affinity Capture-MS Homo sapiens 144 H1FNT   Affinity Capture-MS Homo sapiens 145 CD3EAP   Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 146 WDR46   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 147 CNBP 7555 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 148 FGFBP1 9982 Affinity Capture-MS Homo sapiens 149 HABP4   Affinity Capture-MS Homo sapiens 150 ZBTB2 57621 Affinity Capture-MS Homo sapiens 151 ESF1 51575 Affinity Capture-MS Homo sapiens 152 ZAK 51776 Affinity Capture-MS Homo sapiens 153 IPO5 3843 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 154 SPATS2L 26010 Affinity Capture-MS Homo sapiens 155 ABT1 29777 Affinity Capture-MS Homo sapiens 156 SRSF7 6432 Affinity Capture-MS Homo sapiens 157 MRTO4 51154 Co-fractionation Homo sapiens 158 RPS2 6187 Affinity Capture-MS Homo sapiens 159 RPL15 6138 Affinity Capture-MS Homo sapiens 160 EIF6 3692 Proximity Label-MS Homo sapiens 161 RC3H2   Affinity Capture-MS Homo sapiens 162 SIRT7   Affinity Capture-MS Homo sapiens 163 SRSF4 6429 Affinity Capture-MS Homo sapiens 164 SRSF1 6426 Affinity Capture-MS Homo sapiens 165 NPM3 10360 Affinity Capture-MS Homo sapiens 166 TJP1 7082 Affinity Capture-MS Homo sapiens 167 ISG20L2 81875 Affinity Capture-MS Homo sapiens 168 RPS6 6194 Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 169 DCAF13 25879 Affinity Capture-MS Homo sapiens 170 SRSF5 6430 Affinity Capture-MS Homo sapiens 171 RPL3 6122 Affinity Capture-MS Homo sapiens 172 DNAJC17   Proximity Label-MS Homo sapiens 173 RBM27   Affinity Capture-MS Homo sapiens 174 RPL35 11224 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 175 MYC   Affinity Capture-MS Homo sapiens 176 ZC3H10   Affinity Capture-MS Homo sapiens 177 RFC1 5981 Affinity Capture-MS Homo sapiens 178 RP9   Affinity Capture-MS Homo sapiens 179 SOX15   Affinity Capture-MS Homo sapiens 180 ZNF512   Affinity Capture-MS Homo sapiens 181 BBX 56987 Affinity Capture-MS Homo sapiens 182 RPL36 25873 Affinity Capture-MS Homo sapiens 183 DKC1 1736 Co-fractionation Homo sapiens 184 MYO6 4646 Proximity Label-MS Homo sapiens 185 PSPC1 55269 Affinity Capture-MS Homo sapiens 186 RPA3 6119 Proximity Label-MS Homo sapiens 187 RPP25   Affinity Capture-MS Homo sapiens 188 CEBPZ   Affinity Capture-MS Homo sapiens 189 INO80B 83444 Affinity Capture-MS Homo sapiens 190 NOL12 79159 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 191 MAP9 79884 Affinity Capture-MS Homo sapiens 192 PRRC2A 7916 Affinity Capture-MS Homo sapiens 193 RPL22 6146 Affinity Capture-MS Homo sapiens 194 FAM133B 257415 Affinity Capture-MS Homo sapiens 195 HIST1H1A 3024 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 196 C1D   Affinity Capture-MS Homo sapiens 197 RPL23A 6147 Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 198 RPL18 6141 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 199 DDRGK1 65992 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 200 NSRP1   Affinity Capture-MS Homo sapiens 201 ZC3HAV1 56829 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 202 LYAR 55646 Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens 203 H2AFB2   Affinity Capture-MS Homo sapiens 204 MRPS17 51373 Affinity Capture-MS Homo sapiens 205 FSCN1 6624 Affinity Capture-MS Homo sapiens 206 HIST1H1T 3010 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 207 RPL26 6154 Affinity Capture-MS Homo sapiens 208 ZC3H3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 209 DDX52   Affinity Capture-MS Homo sapiens 210 MAP1A 4130 Affinity Capture-MS Homo sapiens 211 DDX55   Affinity Capture-MS Homo sapiens 212 KIAA1522 57648 Affinity Capture-MS Homo sapiens 213 RSBN1L   Affinity Capture-MS Homo sapiens 214 RPS16 6217 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 215 RPL19 6143 Affinity Capture-MS Homo sapiens 216 DDX46 9879 Affinity Capture-MS Homo sapiens 217 RPL13 6137 Affinity Capture-MS Homo sapiens 218 YBX1 4904 Affinity Capture-MS Homo sapiens 219 DHX16 8449 Affinity Capture-MS Homo sapiens 220 SURF6   Affinity Capture-MS Homo sapiens 221 PLEKHA4 57664 Affinity Capture-MS Homo sapiens 222 RIT1 6016 Negative Genetic Homo sapiens 223 RBM34   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 224 SIRT6   Affinity Capture-MS Homo sapiens 225 PARP1 142 Proximity Label-MS Homo sapiens 226 HMGN4   Affinity Capture-MS Homo sapiens 227 PDGFB   Affinity Capture-MS Homo sapiens 228 ILF3 3609 Affinity Capture-MS Homo sapiens 229 ZFC3H1 196441 Affinity Capture-MS Homo sapiens 230 FBXL6   Affinity Capture-MS Homo sapiens 231 TP53 7157 Affinity Capture-MS Homo sapiens 232 HMMR   Affinity Capture-MS Homo sapiens 233 NLE1 54475 Affinity Capture-MS Homo sapiens 234 MNDA 4332 Affinity Capture-MS Homo sapiens 235 APEX1 328 Proximity Label-MS Homo sapiens 236 MRPS31   Affinity Capture-MS Homo sapiens 237 MEN1 4221 Affinity Capture-MS Homo sapiens 238 UIMC1   Affinity Capture-MS Homo sapiens 239 DGCR8   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 240 KNOP1 400506 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 241 SMURF1 57154 Affinity Capture-MS Homo sapiens 242 G3BP1 10146 Affinity Capture-MS Homo sapiens 243 MRPS15   Affinity Capture-MS Homo sapiens 244 PTBP3 9991 Affinity Capture-MS Homo sapiens 245 NSA2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 246 G3BP2 9908 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 247 H2AFB3   Affinity Capture-MS Homo sapiens 248 MRPS18C   Affinity Capture-MS Homo sapiens 249 CENPU   Affinity Capture-MS Homo sapiens 250 MKI67   Affinity Capture-MS Homo sapiens 251 NIFK 84365 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 252 WBP11   Affinity Capture-MS Homo sapiens 253 ESR1   Affinity Capture-MS Homo sapiens 254 DRG1 4733 Affinity Capture-MS Homo sapiens 255 UFL1 23376 Affinity Capture-MS Homo sapiens 256 KRR1 11103 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 257 RBM4 5936 Affinity Capture-MS Homo sapiens 258 NEIL1   Affinity Capture-MS Homo sapiens 259 OTUD4   Affinity Capture-MS Homo sapiens 260 RPS24 6229 Proximity Label-MS Homo sapiens 261 FGF13   Affinity Capture-MS Homo sapiens 262 DHX38 9785 Affinity Capture-MS Homo sapiens 263 PARK2   Affinity Capture-MS Homo sapiens 264 GLI4   Affinity Capture-MS Homo sapiens 265 CIT 11113 Affinity Capture-MS Homo sapiens 266 RPL8 6132 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 267 POLR3G   Co-fractionation Homo sapiens 268 MFAP1   Affinity Capture-MS Homo sapiens 269 PPAN 56342 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 270 KRAS 3845 Negative Genetic Homo sapiens 271 HNRNPU 3192 Affinity Capture-MS Homo sapiens 272 GNB2L1 10399 Affinity Capture-MS Homo sapiens 273 ZC3H13 23091 Affinity Capture-MS Homo sapiens 274 SRP9 6726 Affinity Capture-MS Homo sapiens 275 RPL36AL 6166 Affinity Capture-MS Homo sapiens 276 RC3H1 149041 Affinity Capture-MS Homo sapiens 277 RBM26 64062 Affinity Capture-MS Homo sapiens 278 RPS3 6188 Affinity Capture-MS Homo sapiens 279 NEMF 9147 Affinity Capture-MS Homo sapiens 280 ZNF467   Affinity Capture-MS Homo sapiens 281 REPIN1   Affinity Capture-MS Homo sapiens 282 DDX56   Affinity Capture-MS Homo sapiens 283 MRPS9 64965 Affinity Capture-MS Homo sapiens 284 RPL17 6139 Affinity Capture-MS Homo sapiens 285 CDC5L 988 Affinity Capture-MS Homo sapiens 286 NHLH1   Proximity Label-MS Homo sapiens 287 ESCO2   Affinity Capture-MS Homo sapiens View the network

Pathways in which GNL2 is involved

No pathways found