Experiment description of studies that identified TMEM41B in sEVs

1 Experiment ID 834 MISEV standards ✔ EM Biophysical techniques ✔ LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 835 MISEV standards ✔ EM Biophysical techniques ✔ CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for TMEM41B

Protein Interactor ExoCarta ID Identification method PubMed Species 1 HNRNPH1 3187 Affinity Capture-RNA Homo sapiens 2 PDE4B   Protein-RNA Homo sapiens 3 MFSD4   Affinity Capture-MS Homo sapiens 4 DYNC1I2 1781 Proximity Label-MS Homo sapiens 5 APOB 338 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 6 TMEM184A   Affinity Capture-MS Homo sapiens 7 HIST1H4A 8359 Affinity Capture-MS Homo sapiens 8 ELAVL1 1994 Affinity Capture-RNA Homo sapiens 9 TMEM72   Affinity Capture-MS Homo sapiens 10 DPYS 1807 Affinity Capture-MS Homo sapiens 11 SLC2A8 29988 Affinity Capture-MS Homo sapiens 12 TTC30B   Affinity Capture-MS Homo sapiens 13 MFSD11   Affinity Capture-MS Homo sapiens 14 MAPK6   Affinity Capture-MS Homo sapiens 15 SREBF2 6721 Negative Genetic Homo sapiens 16 ATP2A1 487 Proximity Label-MS Homo sapiens 17 SPPL2B 56928 Affinity Capture-MS Homo sapiens 18 FPR2   Affinity Capture-MS Homo sapiens 19 VIPR1   Affinity Capture-MS Homo sapiens 20 BMI1   Affinity Capture-MS Homo sapiens 21 KRAS 3845 Negative Genetic Homo sapiens 22 SLC1A1 6505 Affinity Capture-MS Homo sapiens 23 LMNA 4000 Proximity Label-MS Homo sapiens 24 TMEM63A 9725 Affinity Capture-MS Homo sapiens 25 PPP2CB 5516 Affinity Capture-MS Homo sapiens 26 DERL1 79139 Proximity Label-MS Homo sapiens View the network

Pathways in which TMEM41B is involved

No pathways found