Gene description for SLC27A3
Gene name solute carrier family 27 (fatty acid transporter), member 3
Gene symbol SLC27A3
Other names/aliases ACSVL3
FATP3
VLCS-3
Species Homo sapiens
 Database cross references - SLC27A3
ExoCarta ExoCarta_11000
Vesiclepedia VP_11000
Entrez Gene 11000
HGNC 10997
MIM 604193
UniProt Q5K4L6  
 SLC27A3 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for SLC27A3
Molecular Function
    long-chain fatty acid-CoA ligase activity GO:0004467 IBA
    long-chain fatty acid-CoA ligase activity GO:0004467 IDA
    ATP binding GO:0005524 IEA
    very long-chain fatty acid-CoA ligase activity GO:0031957 IDA
    arachidonate-CoA ligase activity GO:0047676 IEA
Biological Process
    long-chain fatty acid metabolic process GO:0001676 IBA
    long-chain fatty acid metabolic process GO:0001676 IDA
    fatty acid transport GO:0015908 IMP
Subcellular Localization
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 IDA
    endoplasmic reticulum GO:0005783 IDA
    endoplasmic reticulum membrane GO:0005789 IBA
    plasma membrane GO:0005886 IBA
    membrane GO:0016020 HDA
    mitochondrial membrane GO:0031966 IEA
 Experiment description of studies that identified SLC27A3 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for SLC27A3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 STUB1 10273
Affinity Capture-MS Homo sapiens
2 NKAIN1  
Affinity Capture-MS Homo sapiens
3 BAG3 9531
Affinity Capture-MS Homo sapiens
4 CYP26B1  
Affinity Capture-MS Homo sapiens
5 FAM189B  
Affinity Capture-MS Homo sapiens
6 KCNMB3  
Affinity Capture-MS Homo sapiens
7 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
8 TMEM9 252839
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 KCNA2  
Affinity Capture-MS Homo sapiens
10 PTH1R  
Affinity Capture-MS Homo sapiens
11 TTYH1  
Affinity Capture-MS Homo sapiens
12 TSPAN17 26262
Affinity Capture-MS Homo sapiens
13 HLA-DMB 3109
Affinity Capture-MS Homo sapiens
14 SIDT2 51092
Affinity Capture-MS Homo sapiens
15 CIB2  
Affinity Capture-MS Homo sapiens
16 ATP5F1 515
Affinity Capture-MS Homo sapiens
17 PCDHGB5 56101
Affinity Capture-MS Homo sapiens
18 HSPA8 3312
Affinity Capture-MS Homo sapiens
19 MFSD4  
Affinity Capture-MS Homo sapiens
20 ZDHHC12  
Affinity Capture-MS Homo sapiens
21 CHRND  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 ADAM33 80332
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 MCOLN3  
Affinity Capture-MS Homo sapiens
24 PIGH  
Affinity Capture-MS Homo sapiens
25 XKR6  
Affinity Capture-MS Homo sapiens
26 CCDC107  
Affinity Capture-MS Homo sapiens
27 SLC12A6 9990
Affinity Capture-MS Homo sapiens
28 C9orf91 203197
Affinity Capture-MS Homo sapiens
29 ERLEC1 27248
Affinity Capture-MS Homo sapiens
30 HSPA4 3308
Affinity Capture-MS Homo sapiens
31 CUL3 8452
Affinity Capture-MS Homo sapiens
32 GPR182  
Affinity Capture-MS Homo sapiens
33 EVA1B 55194
Affinity Capture-MS Homo sapiens
34 SLC12A8  
Affinity Capture-MS Homo sapiens
35 SYVN1 84447
Affinity Capture-MS Homo sapiens
36 SCAP  
Affinity Capture-MS Homo sapiens
37 TMEM150A  
Affinity Capture-MS Homo sapiens
38 TBXA2R 6915
Affinity Capture-MS Homo sapiens
39 KIR3DL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 VSIG4  
Affinity Capture-MS Homo sapiens
41 EVA1C  
Affinity Capture-MS Homo sapiens
42 KIR2DS2  
Affinity Capture-MS Homo sapiens
43 SSTR1 6751
Affinity Capture-MS Homo sapiens
44 ATP5D 513
Affinity Capture-MS Homo sapiens
45 RCCD1  
Affinity Capture-MS Homo sapiens
46 KCNK16  
Affinity Capture-MS Homo sapiens
47 PCDH10 57575
Affinity Capture-MS Homo sapiens
48 ZNRF4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 GPR45  
Affinity Capture-MS Homo sapiens
50 C3orf52  
Affinity Capture-MS Homo sapiens
51 PCDHB3  
Affinity Capture-MS Homo sapiens
52 ASIC1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 AQP3  
Affinity Capture-MS Homo sapiens
54 LHFPL1  
Affinity Capture-MS Homo sapiens
55 TMPRSS3  
Affinity Capture-MS Homo sapiens
56 LIMD1 8994
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 FAM189A2  
Affinity Capture-MS Homo sapiens
58 TGFA  
Affinity Capture-MS Homo sapiens
59 FAM57A  
Affinity Capture-MS Homo sapiens
60 MARCH4  
Affinity Capture-MS Homo sapiens
61 RNF2  
Affinity Capture-MS Homo sapiens
62 GRIN2A  
Affinity Capture-MS Homo sapiens
63 RNF185  
Affinity Capture-MS Homo sapiens
64 LRTM2  
Affinity Capture-MS Homo sapiens
65 SPINT2 10653
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 OR1D4  
Affinity Capture-MS Homo sapiens
67 ATP8  
Affinity Capture-MS Homo sapiens
68 HSPA1B 3304
Affinity Capture-MS Homo sapiens
69 ASB14  
Affinity Capture-MS Homo sapiens
70 ATP5B 506
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 CLRN2  
Affinity Capture-MS Homo sapiens
72 DERL1 79139
Proximity Label-MS Homo sapiens
73 LRFN4  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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